Molecular Mechanical Adhesives

Publicaciones

High force catch bond mechanism of bacterial adhesion in the human gut

Autores: Zhaowei Liu, Haipei Liu, Andrés M. Vera, Rafael C. Bernardi, Philip Tinnefeld, Michael A. Nash
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-18063-x

Next Generation Methods for Single-Molecule Force Spectroscopy on Polyproteins and Receptor-Ligand Complexes

Autores: Byeongseon Yang, Zhaowei Liu, Haipei Liu, Michael A. Nash
Publicado en: Frontiers in Molecular Biosciences, Edición 7, 2020, ISSN 2296-889X
Editor: Frontiers
DOI: 10.3389/fmolb.2020.00085

Adhesive Virulence Factors of Staphylococcus aureus Resist Digestion by Coagulation Proteases Thrombin and Plasmin

Autores: Fanny Risser, Joanan López-Morales, and Michael A. Nash
Publicado en: ACS Bio Med Chem Au, 2022, ISSN 2694-2437
Editor: american chemical society
DOI: 10.1021/acsbiomedchemau.2c00042

Titrating Avidity of Yeast-Displayed Proteins Using a Transcriptional Regulator

Autores: Joanan Lopez-Morales; Rosario Vanella; Gordana Kovacevic; Mariana Sá Santos; Michael A. Nash
Publicado en: ACS Synthetic Biology, Edición 12 (2), 2022, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000601183

Influence of Fluorination on Single-Molecule Unfolding and Rupture Pathways of a Mechanostable Protein Adhesion Complex

Autores: Byeongseon Yang, Haipei Liu, Zhaowei Liu, Regina Doenen, Michael A. Nash
Publicado en: Nano Letters, Edición 20/12, 2020, Página(s) 8940-8950, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c04178

Optimal Sacrificial Domains in Mechanical Polyproteins: S. epidermidis Adhesins Are Tuned for Work Dissipation

Autores: Haipei Liu; Zhaowei Liu; Byeongseon Yang; Joanan Lopez Morales; Michael A. Nash
Publicado en: JACS Au, Edición 2(6), 2022, ISSN 2691-3704
Editor: american chemical society
DOI: 10.1021/jacsau.2c00121

Bioorthogonal Elastin-like Polypeptide Scaffolds for Immunoassay Enhancement

Autores: Duy Tien Ta, Rosario Vanella, Michael A. Nash
Publicado en: ACS Applied Materials & Interfaces, Edición 10/36, 2018, Página(s) 30147-30154, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.8b10092

Combining in Vitro and in Silico Single-Molecule Force Spectroscopy to Characterize and Tune Cellulosomal Scaffoldin Mechanics

Autores: Tobias Verdorfer, Rafael C. Bernardi, Aylin Meinhold, Wolfgang Ott, Zaida Luthey-Schulten, Michael A. Nash, Hermann E. Gaub
Publicado en: Journal of the American Chemical Society, Edición 139/49, 2017, Página(s) 17841-17852, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.7b07574

Mechanical Polyprotein Assembly Using Sfp and Sortase-Mediated Domain Oligomerization for Single-Molecule Studies

Autores: Haipei Liu, Duy Tien Ta, Michael A. Nash
Publicado en: Small Methods, Edición 2/6, 2018, Página(s) 1800039, ISSN 2366-9608
Editor: Wiley
DOI: 10.1002/smtd.201800039

Elastin-like Polypeptide Linkers for Single-Molecule Force Spectroscopy

Autores: Wolfgang Ott, Markus A. Jobst, Magnus S. Bauer, Ellis Durner, Lukas F. Milles, Michael A. Nash, Hermann E. Gaub
Publicado en: ACS Nano, Edición 11/6, 2017, Página(s) 6346-6354, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.7b02694

Removal of a Conserved Disulfide Bond Does Not Compromise Mechanical Stability of a VHH Antibody Complex

Autores: Haipei Liu, Valentin Schittny, Michael A. Nash
Publicado en: Nano Letters, Edición 19/8, 2019, Página(s) 5524-5529, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.9b02062

Mechanisms of Nanonewton Mechanostability in a Protein Complex Revealed by Molecular Dynamics Simulations and Single-Molecule Force Spectroscopy

Autores: Rafael C. Bernardi, Ellis Durner, Constantin Schoeler, Klara H. Malinowska, Bruna G. Carvalho, Edward A. Bayer, Zaida Luthey-Schulten, Hermann E. Gaub, Michael A. Nash
Publicado en: Journal of the American Chemical Society, Edición 141/37, 2019, Página(s) 14752-14763, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.9b06776

Phase Separation of Intrinsically Disordered Protein Polymers Mechanically Stiffens Fibrin Clots

Autores: Ivan Urosev, Joanan Lopez Morales, Michael A. Nash
Publicado en: Advanced Functional Materials, Edición 30/51, 2020, Página(s) 2005245, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202005245

Engineered Molecular Therapeutics Targeting Fibrin and the Coagulation System: a Biophysical Perspective

Autores: Fanny Risser; Ivan Urosev; Joanan López-Morales; Yang Sun; Michael A. Nash
Publicado en: Biophysical Reviews, Edición 14 (2), 2022, ISSN 1867-2469
Editor: Springer
DOI: 10.3929/ethz-b-000544951

Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex

Autores: Zhaowei Liu; Rodrigo A. Moreira; Ana Dujmović; Haipei Liu; Byeongseon Yang; Adolfo B. Poma; Michael A. Nash
Publicado en: Nano Letters, Edición 22 (1), 2022, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.3929/ethz-b-000523717

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