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The role of three-dimensional genome architecture in antigenic variation

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Publications

Genome organization and DNA accessibility control antigenic variation in trypanosomes

Author(s): Laura S. M. Müller, Raúl O. Cosentino, Konrad U. Förstner, Julien Guizetti, Carolin Wedel, Noam Kaplan, Christian J. Janzen, Panagiota Arampatzi, Jörg Vogel, Sascha Steinbiss, Thomas D. Otto, Antoine-Emmanuel Saliba, Robert P. Sebra, T. Nicolai Siegel
Published in: Nature, Issue 563/7729, 2018, Page(s) 121-125, ISSN 0028-0836
DOI: 10.1038/s41586-018-0619-8

Exploiting CRISPR–Cas9 technology to investigate individual histone modifications

Author(s): Juan-José Vasquez, Carolin Wedel, Raul O Cosentino, T Nicolai Siegel
Published in: Nucleic Acids Research, Issue 46/18, 2018, Page(s) e106-e106, ISSN 0305-1048
DOI: 10.1093/nar/gky517

Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes

Author(s): Amelie J. Kraus, Jens T. Vanselow, Stephanie Lamer, Benedikt G. Brink, Andreas Schlosser, T. Nicolai Siegel
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-15274-0

Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes

Author(s): Faria J, Luzak V, Müller LS, Brink BG, Hutchinson S, Glover L, Horn D, Siegel TN
Published in: BioRxiv, 2020
DOI: 10.1101/2020.01.27.921452