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PREcision medicine Drug combination testing In neuroblastoma organoids to guide Clinical Trials

Publications

The landscape of genomic alterations across childhood cancers

Author(s): Susanne N. Gröbner, Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vasilisa A. Rudneva, Pascal D. Johann, Gnana Prakash Balasubramanian, Maia Segura-Wang, Sebastian Brabetz, Sebastian Bender, Barbara Hutter, Dominik Sturm, Elke Pfaff, Daniel Hübschmann, Gideon Zipprich, Michael Heinold, Jürgen Eils, Christian Lawerenz, Serap Erkek, Sander Lambo, Sebastian Waszak, C
Published in: Nature, Issue 555/7696, 2018, Page(s) 321-327, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature25480

Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours

Author(s): David T. W. Jones, Ana Banito, Thomas G. P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Till Milde, Jan J. Molenaar, Arash Nabbi, Trevor J. Pugh, Gudrun Schleiermacher, Malcolm A. Smith, Frank Westermann, Stefan M. Pfister
Published in: Nature Reviews Cancer, Issue 19/8, 2019, Page(s) 420-438, ISSN 1474-175X
Publisher: Nature Publishing Group
DOI: 10.1038/s41568-019-0169-x

High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells.

Author(s): Vernooij, Lindy; Bate-Eya, Laurel T; Alles, Lindy K; Lee, Jasmine Y; Koopmans, Bianca; Jonus, Hunter C; Schubert, Nil A; Schild, Linda; Lelieveld, Daphne; Egan, David A; Kerstjens, Mark; Stam, Ronald W; Koster, Jan; Goldsmith, Kelly C; Molenaar, Jan J; Dolman, M Emmy M; Afd Pharmaceutics; Pharmaceutics
Published in: Mol Cancer Ther, Issue 1, 2021, ISSN 1535-7163
Publisher: American Association for Cancer Research
DOI: 10.1158/1535-7163.mct-20-0666

Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma

Author(s): Wellens, Lianne M; Deken, Marion M; Sier, Cornelis F M; Johnson, Hannah R; de la Jara Ortiz, Fàtima; Bhairosingh, Shadhvi S; Houvast, Ruben D; Kholosy, Waleed M; Baart, Victor M; Pieters, Annique M M J; de Krijger, Ronald R; Molenaar, Jan J; Wehrens, Ellen J; Dekkers, Johanna F; Wijnen, Marc H W A; Vahrmeijer, Alexander L; Rios, Anne C; UU BETA RESEARCH
Published in: Scientific Reports, Issue 1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-74464-4

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