PREcision medicine Drug combination testing In neuroblastoma organoids to guide Clinical Trials

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The landscape of genomic alterations across childhood cancers

Autori: Susanne N. Gröbner, Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vasilisa A. Rudneva, Pascal D. Johann, Gnana Prakash Balasubramanian, Maia Segura-Wang, Sebastian Brabetz, Sebastian Bender, Barbara Hutter, Dominik Sturm, Elke Pfaff, Daniel Hübschmann, Gideon Zipprich, Michael Heinold, Jürgen Eils, Christian Lawerenz, Serap Erkek, Sander Lambo, Sebastian Waszak, C
Pubblicato in: Nature, Numero 555/7696, 2018, Pagina/e 321-327, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/nature25480

Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours

Autori: David T. W. Jones, Ana Banito, Thomas G. P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Till Milde, Jan J. Molenaar, Arash Nabbi, Trevor J. Pugh, Gudrun Schleiermacher, Malcolm A. Smith, Frank Westermann, Stefan M. Pfister
Pubblicato in: Nature Reviews Cancer, Numero 19/8, 2019, Pagina/e 420-438, ISSN 1474-175X
Editore: Nature Publishing Group
DOI: 10.1038/s41568-019-0169-x

High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells.

Autori: Vernooij, Lindy; Bate-Eya, Laurel T; Alles, Lindy K; Lee, Jasmine Y; Koopmans, Bianca; Jonus, Hunter C; Schubert, Nil A; Schild, Linda; Lelieveld, Daphne; Egan, David A; Kerstjens, Mark; Stam, Ronald W; Koster, Jan; Goldsmith, Kelly C; Molenaar, Jan J; Dolman, M Emmy M; Afd Pharmaceutics; Pharmaceutics
Pubblicato in: Mol Cancer Ther, Numero 1, 2021, ISSN 1535-7163
Editore: American Association for Cancer Research
DOI: 10.1158/1535-7163.mct-20-0666

Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma

Autori: Wellens, Lianne M; Deken, Marion M; Sier, Cornelis F M; Johnson, Hannah R; de la Jara Ortiz, Fàtima; Bhairosingh, Shadhvi S; Houvast, Ruben D; Kholosy, Waleed M; Baart, Victor M; Pieters, Annique M M J; de Krijger, Ronald R; Molenaar, Jan J; Wehrens, Ellen J; Dekkers, Johanna F; Wijnen, Marc H W A; Vahrmeijer, Alexander L; Rios, Anne C; UU BETA RESEARCH
Pubblicato in: Scientific Reports, Numero 1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-74464-4

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