European Training Network for Continuous Sonication and Microwave Reactors

Project Information

COSMIC

Grant agreement ID: 721290

DOI 10.3030/721290

Project closed

EC signature date 16 August 2016

Start date 1 October 2016

End date 30 September 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 3 833 301,24

EU contribution € 3 833 301,24

Coordinated by

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

Deliverables

Other (2)

1 COSMIC Symposium
1 COSMIC Summer School

Documents, reports (11)

First paper by ESR14-15
Second paper by ESR10-13
Newsletters

Two newsletters (including policy statements), one in M24 and one in M48.

First paper by ESR5-9
First paper by ESR1-4
First paper by ESR10-13
Final report on COSMIC project
Second paper by ESR5-9
Special Issue Chemical Engineering and Processing: Process Intensification
Second paper by ESR14-15
Second paper by ESR1-4

Websites, patent fillings, videos etc. (2)

Promo videos

Two promo videos, one in M8 and one in M46

Website (external part)

Publications

Peer reviewed articles (47)

Continuous flow synthesis of menthol via tandem cyclisation–hydrogenation of citronellal catalysed by scrap catalytic converters

Author(s): Alessio Zuliani, Camilla Maria Cova, Roberta Manno, Victor Sebastian, Antonio A. Romero, Rafael Luque
Published in: Green Chemistry, Issue 22/2, 2020, Page(s) 379-387, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9gc03299a

Co-precipitation synthesis of stable iron oxide nanoparticles with NaOH: New insights and continuous production via flow chemistry

Author(s): Maximilian O. Besenhard, Alec P. LaGrow, Aden Hodzic, Manfred Kriechbaum, Luca Panariello, Giorgio Bais, Katerina Loizou, Spyridon Damilos, M. Margarida Cruz, Nguyen Thi Kim Thanh, Asterios Gavriilidis
Published in: Chemical Engineering Journal, Issue 399, 2020, Page(s) 125740, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2020.125740

Cavitation bubble dynamics and sonochemiluminescence activity inside sonicated submerged flow tubes

Author(s): Busra Ekim Sarac, Dwayne Savio Stephens, Julian Eisener, Juan Manuel Rosselló, Robert Mettin
Published in: Chemical Engineering and Processing - Process Intensification, Issue 150, 2020, Page(s) 107872, ISSN 0255-2701
Publisher: Elsevier BV
DOI: 10.1016/j.cep.2020.107872

Scrap waste automotive converters as efficient catalysts for the continuous-flow hydrogenations of biomass derived chemicals

Author(s): Camilla Maria Cova, Alessio Zuliani, Roberta Manno, Victor Sebastian, Rafael Luque
Published in: Green Chemistry, Issue 22/4, 2020, Page(s) 1414-1423, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/C9GC04091A

Regeneration of Raney®-Nickel Catalyst for the Synthesis of High-Value Amino-Ester Renewable Monomers

Author(s): Ana Soutelo-Maria, Jean-Luc Dubois, Jean-Luc Couturier, Magali Brebion, Giancarlo Cravotto
Published in: Catalysts, Issue 10/2, 2020, Page(s) 229, ISSN 2073-4344
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal10020229

On the Effect of Secondary Nucleation on Deracemization through Temperature Cycles

Author(s): Fabio Cameli, Joop H. ter Horst, René R. E. Steendam, Christos Xiouras, Georgios D. Stefanidis
Published in: Chemistry – A European Journal, Issue 26/6, 2020, Page(s) 1344-1354, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201904239

Life cycle assessment and cost evaluation of emerging technologies at early stages: The case of continuous flow synthesis of Rufinamide

Author(s): Fabio Grimaldi, Gerardo A. Leon Izeppi, Dirk Kirschneck, Paola Lettieri, Marc Escribà‐Gelonch, Volker Hessel
Published in: Journal of Advanced Manufacturing and Processing, Issue 2/2, 2020, ISSN 2637-403X
Publisher: Wiley
DOI: 10.1002/amp2.10043

Effects of ultrasonic irradiation on crystallization kinetics, morphological and structural properties of zeolite FAU

Author(s): Heidy Ramirez Mendoza, Jeroen Jordens, Mafalda Valdez Lancinha Pereira, Cécile Lutz, Tom Van Gerven
Published in: Ultrasonics Sonochemistry, Issue 64, 2020, Page(s) 105010, ISSN 1350-4177
Publisher: Elsevier BV
DOI: 10.1016/j.ultsonch.2020.105010

Continuous Ultrasonic Reactors: Design, Mechanism and Application

Author(s): Zhengya Dong, Claire Delacour, Keiran Mc Carogher, Aniket Pradip Udepurkar, Simon Kuhn
Published in: Materials, Issue 13/2, 2020, Page(s) 344, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13020344

Highly reproducible, high-yield flow synthesis of gold nanoparticles based on a rational reactor design exploiting the reduction of passivated Au( iii )

Author(s): Luca Panariello, Spyridon Damilos, Hendrik du Toit, Gaowei Wu, Anand N. P. Radhakrishnan, Ivan P. Parkin, Asterios Gavriilidis
Published in: Reaction Chemistry & Engineering, Issue 5/4, 2020, Page(s) 663-676, ISSN 2058-9883
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9re00469f

Economic risk assessment using Monte Carlo simulation for the production of azelaic acid and pelargonic acid from vegetable oils

Author(s): Gerardo Antonio De Leon Izeppi, Jean-Luc Dubois, Antonin Balle, Ana Soutelo-Maria
Published in: Industrial Crops and Products, Issue 150, 2020, Page(s) 112411, ISSN 0926-6690
Publisher: Elsevier BV
DOI: 10.1016/j.indcrop.2020.112411

Theoretical Study of the Scalability of a Sonicated Continuous Crystallizer for the Production of Aspirin

Author(s): Symeon V. Savvopoulos, Mohammed N. Hussain, Tom Van Gerven, Simon Kuhn
Published in: Industrial & Engineering Chemistry Research, Issue 59/45, 2020, Page(s) 19952-19963, ISSN 0888-5885
Publisher: American Chemical Society
DOI: 10.1021/acs.iecr.0c03975

Ligand Enabled Palladium–Catalysed Through‐Space C‐H Bond Activation via a Carbopalladation/1,4‐Pd Migration/C‐H Functionalization Sequence

Author(s): Su Chen, Prabhat Ranjan, Nagarajan Ramkumar, Luc Van Meervelt, Erik V. Van der Eycken, Upendra K. Sharma
Published in: Chemistry – A European Journal, 2020, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202001582

Combining the Ugi-azide multicomponent reaction and rhodium(III)-catalyzed annulation for the synthesis of tetrazole-isoquinolone/pyridone hybrids

Author(s): Gerardo M Ojeda, Prabhat Ranjan, Pavel Fedoseev, Lisandra Amable, Upendra K Sharma, Daniel G Rivera, Erik V Van der Eycken
Published in: Beilstein Journal of Organic Chemistry, Issue 15, 2019, Page(s) 2447-2457, ISSN 1860-5397
Publisher: Beilstein-Institut
DOI: 10.3762/bjoc.15.237

Anticipatory life cycle assessment of gold nanoparticles production: Comparison of milli-continuous flow and batch synthesis

Author(s): Fabio Grimaldi, Martina Pucciarelli, Asterios Gavriilidis, Peter Dobson, Paola Lettieri
Published in: Journal of Cleaner Production, Issue 269, 2020, Page(s) 122335, ISSN 0959-6526
Publisher: Elsevier BV
DOI: 10.1016/j.jclepro.2020.122335

Continuous Microwave-Assisted Synthesis of Silver Nanoclusters Confined in Mesoporous SBA-15: Application in Alkyne Cyclizations

Author(s): Roberta Manno, Prabhat Ranjan, Victor Sebastian, Reyes Mallada, Silvia Irusta, Upendra K. Sharma, Erik V. Van der Eycken, Jesús Santamaria
Published in: Chemistry of Materials, Issue 32/7, 2020, Page(s) 2874-2883, ISSN 0897-4756
Publisher: American Chemical Society
DOI: 10.1021/acs.chemmater.9b04935

Efficient and Environmentally Friendly Microwave-Assisted Synthesis of Catalytically Active Magnetic Metallic Ni Nanoparticles

Author(s): Alessio Zuliani, Alina M. Balu, Rafael Luque
Published in: ACS Sustainable Chemistry & Engineering, Issue 5/12, 2017, Page(s) 11584-11587, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.7b02945

Advances in Nanocatalyst Design for Biofuel Production

Author(s): Alessio Zuliani, Francisco Ivars, Rafael Luque
Published in: ChemCatChem, Issue 10/9, 2018, Page(s) 1968-1981, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201701712

Microwave-assisted valorization of pig bristles: towards visible light photocatalytic chalcocite composites

Author(s): Alessio Zuliani, Mario J. Muñoz-Batista, Rafael Luque
Published in: Green Chemistry, Issue 20/13, 2018, Page(s) 3001-3007, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8GC00669E

Modelling the synthesis of nanoparticles in continuous microreactors: The role of diffusion and residence time distribution on nanoparticle characteristics

Author(s): Luca Panariello, Luca Mazzei, Asterios Gavriilidis
Published in: Chemical Engineering Journal, Issue 350, 2018, Page(s) 1144-1154, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2018.03.167

Intensified deracemization via rapid microwave-assisted temperature cycling

Author(s): Fabio Cameli, Christos Xiouras, Georgios D. Stefanidis
Published in: CrystEngComm, Issue 20/21, 2018, Page(s) 2897-2901, ISSN 1466-8033
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8ce00575c

Ex Situ Generation of Sulfuryl Fluoride for the Synthesis of Aryl Fluorosulfates

Author(s): Cedrick Veryser, Joachim Demaerel, Vidmantas Bieliu̅nas, Philippe Gilles, Wim M. De Borggraeve
Published in: Organic Letters, Issue 19/19, 2017, Page(s) 5244-5247, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.7b02522

Novel Applications of Microbial Fuel Cells in Sensors and Biosensors

Author(s): Francisco Ivars-Barceló, Alessio Zuliani, Marjan Fallah, Mehrdad Mashkour, Mostafa Rahimnejad, Rafael Luque
Published in: Applied Sciences, Issue 8/7, 2018, Page(s) 1184, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/app8071184

Microwave-assisted preparation of Ag/Ag 2 S carbon hybrid structures from pig bristles as efficient HER catalysts

Author(s): Camilla Maria Cova, Alessio Zuliani, Alain R. Puente Santiago, Alvaro Caballero, Mario J. Muñoz-Batista, Rafael Luque
Published in: Journal of Materials Chemistry A, Issue 6/43, 2018, Page(s) 21516-21523, ISSN 2050-7488
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8TA06417B

Oxidative Cleavage of Fatty Acid Derivatives for Monomer Synthesis

Author(s): Ana Soutelo-Maria, Jean-Luc Dubois, Jean-Luc Couturier, Giancarlo Cravotto
Published in: Catalysts, Issue 8/10, 2018, Page(s) 464, ISSN 2073-4344
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal8100464

Heterogeneously Catalyzed Synthesis of Imidazolones via Cycloisomerizations of Propargylic Ureas Using Ag and Au/Al SBA-15 Systems

Author(s): Alessio Zuliani, Prabhat Ranjan, Rafael Luque, Erik V. Van der Eycken
Published in: ACS Sustainable Chemistry & Engineering, Issue 7/5, 2019, Page(s) 5568-5575, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.9b00198

Preliminary economic assessment of a polymer production plant in batch and continuous manufacturing

Author(s): DE LEON IZEPPI, GERARDO ANTONIO; DREXLER, CHRISTIAN; KIRSCHNECK, DIRK
Published in: Chimica Oggi - Chemistry Today 36(5) 35-39, Issue 36(5), 2018, Page(s) 36-39, ISSN 0392-839X
Publisher: Teknoscienze s.r.l.
DOI: 10.5281/zenodo.1584963

110th Anniversary: Nucleation of Ag Nanoparticles in Helical Microfluidic Reactor. Comparison between Microwave and Conventional Heating

Author(s): Roberta Manno, Victor Sebastian, Reyes Mallada, Jesús Santamaria
Published in: Industrial & Engineering Chemistry Research, Issue 58/28, 2019, Page(s) 12702-12711, ISSN 0888-5885
Publisher: American Chemical Society
DOI: 10.1021/acs.iecr.9b01460

Pulsed ultrasound for temperature control and clogging prevention in micro-reactors

Author(s): Claire Delacour, Cecile Lutz, Simon Kuhn
Published in: Ultrasonics Sonochemistry, Issue 55, 2019, Page(s) 67-74, ISSN 1350-4177
Publisher: Elsevier BV
DOI: 10.1016/j.ultsonch.2019.03.012

Sonochemically-Promoted Preparation of Silica-Anchored Cyclodextrin Derivatives for Efficient Copper Catalysis

Author(s): Katia Martina, Federica Calsolaro, Alessio Zuliani, Gloria Berlier, Fernando Chávez-Rivas, Maria Jesus Moran, Rafael Luque, Giancarlo Cravotto
Published in: Molecules, Issue 24/13, 2019, Page(s) 2490, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24132490

Sonocrystallisation: Observations, theories and guidelines

Author(s): Jeroen Jordens, Bjorn Gielen, Christos Xiouras, Mohammed Noorul Hussain, Georgios D. Stefanidis, Leen C.J. Thomassen, Leen Braeken, Tom Van Gerven
Published in: Chemical Engineering and Processing - Process Intensification, Issue 139, 2019, Page(s) 130-154, ISSN 0255-2701
Publisher: Elsevier BV
DOI: 10.1016/j.cep.2019.03.017

A Mathematical Model of the Ultrasound-Assisted Continuous Tubular Crystallization of Aspirin

Author(s): Symeon V. Savvopoulos, Mohammed N. Hussain, Jeroen Jordens, Steffen Waldherr, Tom Van Gerven, Simon Kuhn
Published in: Crystal Growth & Design, Issue 19/9, 2019, Page(s) 5111-5122, ISSN 1528-7483
Publisher: American Chemical Society
DOI: 10.1021/acs.cgd.9b00466

Enhancing pharmaceutical crystallization in a flow crystallizer with ultrasound: Anti-solvent crystallization

Author(s): M.N. Hussain, J. Jordens, J.J. John, L. Braeken, T. Van Gerven
Published in: Ultrasonics Sonochemistry, Issue 59, 2019, Page(s) 104743, ISSN 1350-4177
Publisher: Elsevier BV
DOI: 10.1016/j.ultsonch.2019.104743

Glycerol: An Optimal Hydrogen Source for Microwave-Promoted Cu-Catalyzed Transfer Hydrogenation of Nitrobenzene to Aniline

Author(s): Maria Jesus Moran, Katia Martina, Georgios D. Stefanidis, Jeroen Jordens, Tom Van Gerven, Vincent Goovaerts, Maela Manzoli, Carlo Groffils, Giancarlo Cravotto
Published in: Frontiers in Chemistry, Issue 8, 2020, ISSN 2296-2646
Publisher: Frontiers
DOI: 10.3389/fchem.2020.00034

Tuneable Copper Catalysed Transfer Hydrogenation of Nitrobenzenes to Aniline or Azo Derivatives

Author(s): Maria Jesus Moran, Katia Martina, Francesca Baricco, Silvia Tagliapietra, Maela Manzoli, Giancarlo Cravotto
Published in: Advanced Synthesis & Catalysis, Issue 362, 2020, ISSN 1615-4150
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.202000127

A model for the formation of gold nanoparticles in the citrate synthesis method

Author(s): Emmanuel Agunloye, Luca Panariello, Asterios Gavriilidis, Luca Mazzei
Published in: Chemical Engineering Science, Issue 191, 2018, Page(s) 318-331, ISSN 0009-2509
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.ces.2018.06.046

Introduction of Aryl Fluorosulfates into the Realm of Catellani Reaction Substrates

Author(s): Vidmantas Bieliu̅nas, Wim M. De Borggraeve
Published in: The Journal of Organic Chemistry, Issue 84/23, 2019, Page(s) 15706-15717, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.9b02352

Multistep Solvent-Free 3 m 2 Footprint Pilot Miniplant for the Synthesis of Annual Half-Ton Rufinamide Precursor

Author(s): Marc Escribà-Gelonch, Gerardo Antonio de Leon Izeppi, Dirk Kirschneck, Volker Hessel
Published in: ACS Sustainable Chemistry & Engineering, Issue 7/20, 2019, Page(s) 17237-17251, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.9b03931

Metal‐Free Dearomatization: Direct Access to Spiroindol(en)ines in Batch and Continuous‐Flow

Author(s): Prabhat Ranjan, Gerardo M. Ojeda, Upendra K. Sharma, Erik V. Van der Eycken
Published in: Chemistry – A European Journal, Issue 25/10, 2019, Page(s) 2442-2446, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201805945

A Sustainable Approach for the Synthesis of Catalytically Active Peroxidase-Mimic ZnS Catalysts

Author(s): Camilla M. Cova, Alessio Zuliani, Mario J. Muñoz-Batista, Rafael Luque
Published in: ACS Sustainable Chemistry & Engineering, Issue 7/1, 2018, Page(s) 1300-1307, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.8b04968

Ultrasound as a tool for polymorph control and high yield in flow crystallization

Author(s): Mohammed Noorul Hussain, Jeroen Jordens, Simon Kuhn, Leen Braeken, Tom Van Gerven
Published in: Chemical Engineering Journal, 2020, Page(s) 127272, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2020.127272

Synthetic guidelines for the precision engineering of gold nanoparticles

Author(s): Jakub W Trzciński, Luca Panariello, Maximilian O Besenhard, Ye Yang, Asterios Gavriilidis, Stefan Guldin
Published in: Current Opinion in Chemical Engineering, Issue 29, 2020, Page(s) 59-66, ISSN 2211-3398
Publisher: Elsevier BV
DOI: 10.1016/j.coche.2020.05.004

Process intensified anti-solvent crystallization of o-aminobenzoic acid via sonication and flow

Author(s): Mohammed Noorul Hussain, Stijn Baeten, Jeroen Jordens, Leen Braeken, Tom Van Gerven
Published in: Chemical Engineering and Processing - Process Intensification, Issue 149, 2020, Page(s) 107823, ISSN 0255-2701
Publisher: Elsevier BV
DOI: 10.1016/j.cep.2020.107823

Sustainable Protocol for the Reduction of Nitroarenes by Heterogeneous Au@SBA‐15 with NaBH 4 under Flow Conditions

Author(s): Francesco Ferlin, Tommaso Giannoni, Alessio Zuliani, Oriana Piermatti, Rafael Luque, Luigi Vaccaro
Published in: ChemSusChem, Issue 12/13, 2019, Page(s) 3178-3184, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.201802359

Continuous flow synthesis of zeolite FAU in an oscillatory baffled reactor

Author(s): Heidy Ramirez Mendoza, Mafalda Valdez Lancinha Pereira, Tom Van Gerven, Cécile Lutz
Published in: Journal of Advanced Manufacturing and Processing, Issue 2/2, 2020, ISSN 2637-403X
Publisher: Wiley
DOI: 10.1002/amp2.10038

A Modular Millifluidic Platform for the Synthesis of Iron Oxide Nanoparticles with Control over Dissolved Gas and Flow Configuration

Author(s): Luca Panariello, Gaowei Wu, Maximilian O. Besenhard, Katerina Loizou, Liudmyla Storozhuk, Nguyen Thi Kim Thanh, Asterios Gavriilidis
Published in: Materials, Issue 13/4, 2020, Page(s) 1019, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13041019

Efficient Ru-based scrap waste automotive converter catalysts for the continuous-flow selective hydrogenation of cinnamaldehyde

Author(s): Camilla Maria Cova, Alessio Zuliani, Mario J. Muñoz-Batista, Rafael Luque
Published in: Green Chemistry, Issue 21/17, 2019, Page(s) 4712-4722, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9gc01596e

Thesis and dissertations (2)

Microwave-assisted synthesis of nanocatalysts in batch conditions

Author(s): Zuliani, Alessio
Published in: Issue 1, 2019
Publisher: University of Cordoba, UCOPress

ULTRASOUND-ASSISTED SYNTHESIS OF ZEOLITE CATALYSTS

Author(s): Heidy RAMIREZ MENDOZA
Published in: 2020
Publisher: KU leuven

Conference proceedings (1)

Can the use of captured CO2 lower the environmental impacts of formate production?

Author(s): Pucciarelli, M; Grimaldi, F; Paulillo, A; Lettieri, P
Published in: Proceedings of Chemeca 2019: Chemical Engineering Megatrends and Elements, Issue Chemeca 2019, 2019, Page(s) 324-335
Publisher: Informit

Book chapters (2)

Flow Chemistry for the Synthesis of Heterocycles

Author(s): Joachim Demaerel, Vidmantas Bieliūnas, Wim M. De Borggraeve
Published in: Functionalization of Heteroarenes Under Continuous Flow, Issue Volume 56, 2018, Page(s) 237-317, ISBN 3319-943286
Publisher: Springer International Publishing
DOI: 10.1007/7081_2018_22

Continuous Synthesis of Gold Nanoparticles in Micro- and Milli-fluidic Systems

Author(s): Huang, H.; Du Toit, H.; Panariello, L.; Mazzei, L.; Gavriilidis, A.
Published in: In: Kumar, C, (ed.) Chemistry of Nanomaterials: A Practical Guide. Volume 1: Metallic Nanomaterials (Part A). (pp. 157-220). De Gruyter: Berlin, Germany. (2018), Issue 2, 2019
Publisher: De Gruyter
DOI: 10.1515/9783110345100-004