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Reverse Engineering Gene Regulatory Networks

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A partially self-regenerating synthetic cell

Author(s): Barbora Lavickova, Nadanai Laohakunakorn, Sebastian J. Maerkl
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-20180-6

A high-throughput microfluidic nanoimmunoassay for detecting anti–SARS-CoV-2 antibodies in serum or ultralow-volume blood samples

Author(s): Zoe Swank, Grégoire Michielin, Hon Ming Yip, Patrick Cohen, Diego O. Andrey, Nicolas Vuilleumier, Laurent Kaiser, Isabella Eckerle, Benjamin Meyer, Sebastian J. Maerkl
Published in: Proceedings of the National Academy of Sciences, Issue 118/18, 2021, Page(s) e2025289118, ISSN 0027-8424
DOI: 10.1073/pnas.2025289118

Microfluidic Module for Real-Time Generation of Complex Multimolecule Temporal Concentration Profiles

Author(s): Kristina Woodruff, Sebastian J. Maerkl
Published in: Analytical Chemistry, Issue 90/1, 2017, Page(s) 696-701, ISSN 0003-2700
DOI: 10.1021/acs.analchem.7b04099

Microfluidic device for real-time formulation of reagents and their subsequent encapsulation into double emulsions

Author(s): Jui-Chia Chang, Zoe Swank, Oliver Keiser, Sebastian J. Maerkl, Esther Amstad
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-26542-x

Cell-free gene-regulatory network engineering with synthetic transcription factors

Author(s): Zoe Swank, Nadanai Laohakunakorn, Sebastian J. Maerkl
Published in: Proceedings of the National Academy of Sciences, Issue 116/13, 2019, Page(s) 5892-5901, ISSN 0027-8424
DOI: 10.1073/pnas.1816591116

Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory

Author(s): Poonam Bheda, Diana Aguilar-Gómez, Nils B. Becker, Johannes Becker, Emmanouil Stavrou, Igor Kukhtevich, Thomas Höfer, Sebastian Maerkl, Gilles Charvin, Carsten Marr, Antonis Kirmizis, Robert Schneider
Published in: Molecular Cell, 2020, ISSN 1097-2765
DOI: 10.1016/j.molcel.2020.04.016

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Author(s): Ardjan J. van der Linden, Maaruthy Yelleswarapu, Pascal A. Pieters, Zoe Swank, Wilhelm T. S. Huck, Sebastian J. Maerkl, Tom F. A. de Greef
Published in: Journal of Visualized Experiments, Issue 152, 2019, ISSN 1940-087X
DOI: 10.3791/59655

Bottom-Up Construction of Complex Biomolecular Systems With Cell-Free Synthetic Biology

Author(s): Nadanai Laohakunakorn, Laura Grasemann, Barbora Lavickova, Grégoire Michielin, Amir Shahein, Zoe Swank, Sebastian J. Maerkl
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, ISSN 2296-4185
DOI: 10.3389/fbioe.2020.00213

A Simple, Robust, and Low-Cost Method To Produce the PURE Cell-Free System

Author(s): Barbora Lavickova, Sebastian J. Maerkl
Published in: ACS Synthetic Biology, Issue 8/2, 2019, Page(s) 455-462, ISSN 2161-5063
DOI: 10.1021/acssynbio.8b00427

CFPU: A Cell-Free Processing Unit for High-Throughput, Automated In Vitro Circuit Characterization in Steady-State Conditions

Author(s): Zoe Swank, Sebastian J. Maerkl
Published in: BioDesign Research, Issue 2021, 2021, Page(s) 1-11, ISSN 2693-1257
DOI: 10.34133/2021/2968181