Functional Biology of Hepatic CD8+ T cells

Publicaciones

A subset of Kupffer cells regulates metabolism through the expression of CD36.

Autores: Blériot C, Barreby E, Dunsmore G, Ballaire R, Chakarov S, Ficht X, De Simone G, Andreata F, Fumagalli V, Guo W, Wan G, Gessain G, Khalilnezhad A, Zhang XM, Ang N, Chen P, Morgantini C, Azzimato V, Kong WT, Liu Z, Pai R, Lum J, Shihui F, Low I, Xu C, Malleret B, Kairi MFM, Balachander A, Cexus O, Larbi A, Lee B, Newell EW, Ng LG, Phoo WW, Sobota RM, Sharma A, Howland SW, Chen J, Bajenoff M, Yvan-C
Publicado en: Immunity, 2021, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2021.08.006

The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response

Autores: Cohen M, Giladi A, Barboy O, Hamon P, Li B, Zada M, Gurevich-Shapiro A, Beccaria CG, David E, Maier BB, Buckup M, Kamer I, Deczkowska A, Le Berichel J, Bar J, Iannacone M, Tanay A, Merad M, Amit I.
Publicado en: Nature cancer, 2022, ISSN 2662-1347
Editor: Nature Publishing Group
DOI: 10.1038/s43018-022-00338-5

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming.

Autores: De Simone G, Andreata F, Bleriot C, Fumagalli V, Laura C, Garcia-Manteiga JM, Di Lucia P, Gilotto S, Ficht X, De Ponti FF, Bono EB, Giustini L, Ambrosi G, Mainetti M, Zordan P, Bénéchet AP, Ravà M, Chakarov S, Moalli F, Bajenoff M, Guidotti LG, Ginhoux F, Iannacone M.
Publicado en: Immunity, 2021, ISSN 1074-7613
Editor: Cell Press
DOI: 10.1016/j.immuni.2021.05.005

CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential.

Autores: "De Simone, G.; Mazza, E.M.C.; Cassotta, A.; Davydov, A.N.; Kuka, M.; Zanon, V.; De Paoli, F.; Scamardella, E.; Metsger, M.; Roberto, A.; Pilipow, K.; Colombo, F.S.; Tenedini, E.; Tagliafico, E.; Gattinoni, L.; Mavilio, D.; Peano, C.; Price, D.A.; Singh, S.P.; Farber, J.M.; Serra, V.; Cucca, F.; Ferrari, F.; Orrù , V.; Fiorillo, E.; Iannacone, M.; Chudakov, D.M.; Sallusto, F.; Lugli, E."
Publicado en: The Journal of Immunology, Edición 1, 2019, ISSN 1550-6606
Editor: AAI
DOI: 10.4049/jimmunol.1901072

Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability

Autores: Fumagalli V, Venzin V, Di Lucia P, Moalli F, Ficht X, Ambrosi G, Giustini L, Andreata F, Grillo M, Magini D, Ravà M, Friedrich C, Fontenot JD, Bousso P, Gilmore SA, Khan S, Baca M, Vivier E, Gasteiger G, Kuka M, Guidotti LG, Iannacone M.
Publicado en: Science immunology, 2022, ISSN 2470-9468
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.abi6112

Heterogeneity in antiviral B cell responses: Lessons from the movies.

Autores: Mirela Kuka; Matteo Iannacone
Publicado en: Immunological Reviews, Edición 1, 2021, ISSN 1600-065X
Editor: Wiley
DOI: 10.1111/imr.13041

Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection.

Autores: Valeria Fumagalli; Pietro Di Lucia; Valentina Venzin; Elisa Bono; Robert Jordan; Christian R. Frey; William Delaney; Francis V. Chisari; Luca G. Guidotti; Matteo Iannacone
Publicado en: The Journal of Experimental Medicine, Edición 1, 2021, ISSN 0022-1007
Editor: Rockefeller University Press
DOI: 10.1084/jem.20200298

The conduit system exports locally secreted IgM from lymph nodes

Autores: Guilhem R. Thierry, Mirela Kuka, Marco De Giovanni, Isabelle Mondor, Nicolas Brouilly, Matteo Iannacone, Marc Bajénoff
Publicado en: The Journal of Experimental Medicine, Edición 215/12, 2018, Página(s) 2972-2983, ISSN 0022-1007
Editor: Rockefeller University Press
DOI: 10.1084/jem.20180344

The role of type I interferons in CD4+ T cell differentiation

Autores: Mirela Kuka, Marco De Giovanni, Matteo Iannacone
Publicado en: Immunology Letters, 2019, ISSN 0165-2478
Editor: Elsevier BV
DOI: 10.1016/j.imlet.2019.01.013

Viral subversion of B cell responses within secondary lymphoid organs

Autores: Mirela Kuka, Matteo Iannacone
Publicado en: Nature Reviews Immunology, Edición 18/4, 2018, Página(s) 255-265, ISSN 1474-1733
Editor: Nature Publishing Group
DOI: 10.1038/nri.2017.133

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Autores: Alexandre P. Bénéchet, Giorgia De Simone, Pietro Di Lucia, Francesco Cilenti, Giulia Barbiera, Nina Le Bert, Valeria Fumagalli, Eleonora Lusito, Federica Moalli, Valentina Bianchessi, Francesco Andreata, Paola Zordan, Elisa Bono, Leonardo Giustini, Weldy V. Bonilla, Camille Bleriot, Kamini Kunasegaran, Gloria Gonzalez-Aseguinolaza, Daniel D. Pinschewer, Patrick T. F. Kennedy, Luigi Naldini, Mire
Publicado en: Nature, Edición 574/7777, 2019, Página(s) 200-205, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-019-1620-6

Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4+ T cells

Autores: Marco De Giovanni, Valeria Cutillo, Amir Giladi, Eleonora Sala, Carmela G. Maganuco, Chiara Medaglia, Pietro Di Lucia, Elisa Bono, Claudia Cristofani, Eleonora Consolo, Leonardo Giustini, Alessandra Fiore, Sarah Eickhoff, Wolfgang Kastenmüller, Ido Amit, Mirela Kuka, Matteo Iannacone
Publicado en: Nature Immunology, Edición 21/3, 2020, Página(s) 321-330, ISSN 1529-2908
Editor: Nature Publishing Group
DOI: 10.1038/s41590-020-0596-6

Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators

Autores: Ivanova Bencheva L, Donnici L, Ferrante L, Prandi A, Sinisi R, De Matteo M, Randazzo P, Conti M, Di Lucia P, Bono E, Giustini L, Vittoria Orsale M, Patsilinakos A, Monteagudo E, Iannacone M, Summa V, Guidotti LG, De Francesco R, Di Fabio R.
Publicado en: Bioorganic & medicinal chemistry letters, 2022, ISSN 0960-894X
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.bmcl.2022.128904

Immune surveillance of the liver by T cells.

Autores: Xenia Ficht; Matteo Iannacone
Publicado en: Science Immunology, Edición 1, 2020, ISSN 2470-9468
Editor: AAAS
DOI: 10.1126/sciimmunol.aba2351

In vivo imaging of adaptive immune responses to viruses.

Autores: Marco De Giovanni; Matteo Iannacone
Publicado en: Current Opinion in Virology, Edición 1, 2018, ISSN 1879-6265
Editor: Elsevier
DOI: 10.1016/j.coviro.2017.12.002

Immunological insights in the treatment of chronic hepatitis B

Autores: Matteo Iannacone, Francesco Andreata, Luca G Guidotti
Publicado en: Current opinion in immunology, 2022, ISSN 0952-7915
Editor: Elsevier BV
DOI: 10.1016/j.coi.2022.102207

Immunobiology and pathogenesis of hepatitis B virus infection.

Autores: Iannacone M, Guidotti LG.
Publicado en: Nature reviews. Immunology., 2022, ISSN 1474-1733
Editor: Nature Publishing Group
DOI: 10.1038/s41577-021-00549-4

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