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Chemical proteome mining for functional annotation of disease relevant proteins

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Publications

Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping

Author(s): Jonas Drechsel, Christina Kyrousi, Silvia Cappello, Stephan A. Sieber
Published in: RSC Chemical Biology, 1/4, 2020, Page(s) 209-213, ISSN 2633-0679
Publisher: RSC
DOI: 10.1039/d0cb00048e

Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome

Author(s): Anja Fux, Martin Pfanzelt, Volker C. Kirsch, Annabelle Hoegl, Stephan A. Sieber
Published in: Cell Chemical Biology, 26/10, 2019, Page(s) 1461-1468.e7, ISSN 2451-9456
Publisher: Elsivier
DOI: 10.1016/j.chembiol.2019.08.003

Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics

Author(s): Annabelle Hoegl, Matthew B. Nodwell, Volker C. Kirsch, Nina C. Bach, Martin Pfanzelt, Matthias Stahl, Sabine Schneider, Stephan A. Sieber
Published in: Nature Chemistry, 10/12, 2018, Page(s) 1234-1245, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-018-0144-2

A Pronucleotide Probe for Live‐Cell Imaging of Protein AMPylation

Author(s): Pavel Kielkowski, Isabel Y. Buchsbaum, Tobias Becker, Kathrin Bach, Silvia Cappello, Stephan A. Sieber
Published in: ChemBioChem, 2020, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201900716

FICD activity and AMPylation remodelling modulate human neurogenesis

Author(s): Pavel Kielkowski, Isabel Y. Buchsbaum, Volker C. Kirsch, Nina C. Bach, Micha Drukker, Silvia Cappello, Stephan A. Sieber
Published in: Nature Communications, 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-14235-6

Biochemical and Proteomic Studies of Human Pyridoxal 5′-Phosphate-Binding Protein (PLPBP)

Author(s): Anja Fux, Stephan A. Sieber
Published in: ACS Chemical Biology, 15/1, 2019, Page(s) 254-261, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.9b00857

A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling

Author(s): Patrick W. A. Allihn, Mathias W. Hackl, Christina Ludwig, Stephan M. Hacker, Stephan A. Sieber
Published in: Chemical Science, 12/13, 2021, Page(s) 4763-4770, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc06226j

MS-Based in Situ Proteomics Reveals AMPylation of Host Proteins during Bacterial Infection

Author(s): Theresa Rauh, Sophie Brameyer, Pavel Kielkowski, Kirsten Jung, Stephan A. Sieber
Published in: ACS Infectious Diseases, 6/12, 2020, Page(s) 3277-3289, ISSN 2373-8227
Publisher: ACS
DOI: 10.1021/acsinfecdis.0c00740