Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development

Información del proyecto

LinPro

Identificador del acuerdo de subvención: 725780

DOI

10.3030/725780

Proyecto cerrado

Fecha de la firma de la CE 16 Noviembre 2017

Fecha de inicio 1 Diciembre 2017

Fecha de finalización 30 Noviembre 2022

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 996 030,00

Aportación de la UE

€ 1 996 030,00

Coordinado por

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (23)

SymposiumThe Logic of Developing Neocortical Circuits in Health and Disease

Autores: Hanganu-Opatz IL, Butt SJB, Hippenmeyer S, De Marco García NV, Cardin JA, Voytek B, Muotri AR
Publicado en: The Journal of Neuroscience, 2021, ISSN 1529-2401
Editor: Society for Neuroscience
DOI: 10.1523/jneurosci.1655-20.2020

GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells

Autores: Yukari H.Takeo, Andrew Shuster, LinnieJiang, Miley C.Hu, David J.Luginbuhl, Thomas Rülicke, Ximena Contreras, Simon Hippenmeyer, Mark J.Wagner, Surya Ganguli, LiqunLuo
Publicado en: Neuron, 2021, ISSN 1097-4199
Editor: Science Direct
DOI: 10.1016/j.neuron.2020.11.028

A genome-wide library of MADM mice for single-cell genetic mosaic analysis

Autores: Contreras X, Amberg N, Davaatseren A, Hansen AH, Sonntag J, Andersen L, Bernthaler T, Streicher C, Heger A-M, Johnson RL, Schwarz LA, Luo L, Rülicke T, Hippenmeyer S
Publicado en: Cell Reports, 2021, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2021.109274

Principles of neural stem cell lineage progression: Insights from developing cerebral cortex

Autores: Simon Hippenmeyer
Publicado en: Current Opinion in Neurobiology, Edición 102695, 2023, ISSN 0959-4388
Editor: Elsevier BV
DOI: 10.1016/j.conb.2023.102695

Clonal analysis of gliogenesis in the cerebral cortex reveals stochastic expansion of glia and cell autonomous responses to Egfr dosage

Autores: Xuying Zhang, Christine V. Mennicke, Guanxi Xiao, Robert Beattie, Mansoor A. Haider, Simon Hippenmeyer and H. Troy Ghashghaei
Publicado en: Cells, 2020, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells9122662

Oncogenic State and Cell Identity Combinatorially Dictate the Susceptibility of Cells within Glioma Development Hierarchy to IGF1R Targeting

Autores: Anhao Tian, Bo Kang, Baizhou Li, Biying Qiu, Wenhong Jiang, Fangjie Shao, Qingqing Gao, Rui Liu, Chengwei Cai, Rui Jing, Wei Wang, Pengxiang Chen, Qinghui Liang, Lili Bao, Jianghong Man, Yan Wang, Yu Shi, Jin Li, Minmin Yang, Lisha Wang, Jianmin Zhang, Simon Hippenmeyer, Junming Zhu, Xiuwu Bian, Ying‐Jie Wang, Chong Liu
Publicado en: Advanced Science, Edición 7/21, 2020, Página(s) 2001724, ISSN 2198-3844
Editor: Advanced Science
DOI: 10.1002/advs.202001724

Generation and isolation of single cells from mouse brain with mosaic analysis with double markers-induced uniparental chromosome disomy

Autores: Laukoter, Susanne; Amberg, Nicole ; Pauler, Florian; Hippenmeyer, Simon
Publicado en: STAR Protocols, 2020, ISSN 2666-1667
Editor: Cell Press OA
DOI: 10.1016/j.xpro.2020.100215

Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum

Autores: Zhang T, Liu T, Mora N, Guegan J, Bertrand M, Contreras X, Hansen AH, Streicher C, Anderle M, Danda N, Tiberi L, Hippenmeyer S, Hassan BA.
Publicado en: Cell Reports, 2021, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2021.109208

Tissue-wide Genetic and Cellular Landscape Shapes the Execution of Sequential PRC2 Functions in Neural Stem Cell Lineage Progression

Autores: Amberg, N., Pauler, FM., Streicher, C. & Hippenmeyer, S.
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abq1263

Inducible uniparental chromosome disomy to probe genomic imprinting at single-cell level in brain and beyond

Autores: Florian M.Pauler, Quanah J.Hudson, Susanne Laukoter, Simon Hippenmeyer
Publicado en: Neurochemistry International, 2021, ISSN 0197-0186
Editor: Elsevier BV
DOI: 10.1016/j.neuint.2021.104986

A mathematical insight into cell labelling experiments for clonal analysis

Autores: Noemi Picco, Simon Hippenmeyer, Julio Rodarte, Carmen Streicher, Zoltán Molnár, Philip K. Maini, Thomas E. Woolley
Publicado en: Journal of Anatomy, 2019, ISSN 0021-8782
Editor: Blackwell Publishing Inc.
DOI: 10.1111/joa.13001

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex

Autores: L. Telley, G. Agirman, J. Prados, N. Amberg, S. Fièvre, P. Oberst, G. Bartolini, I. Vitali, C. Cadilhac, S. Hippenmeyer, L. Nguyen, A. Dayer, D. Jabaudon
Publicado en: Science, Edición 364/6440, 2019, Página(s) eaav2522, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aav2522

Adult Neural Stem Cells and Multiciliated Ependymal Cells Share a Common Lineage Regulated by the Geminin Family Members

Autores: Gonzalo Ortiz-Álvarez, Marie Daclin, Asm Shihavuddin, Pauline Lansade, Aurélien Fortoul, Marion Faucourt, Solène Clavreul, Maria-Eleni Lalioti, Stavros Taraviras, Simon Hippenmeyer, Jean Livet, Alice Meunier, Auguste Genovesio, Nathalie Spassky
Publicado en: Neuron, Edición 102/1, 2019, Página(s) 159-172.e7, ISSN 0896-6273
Editor: Cell Press
DOI: 10.1016/j.neuron.2019.01.051

Epigenetic cues modulating the generation of cell‐type diversity in the cerebral cortex

Autores: Nicole Amberg, Susanne Laukoter, Simon Hippenmeyer
Publicado en: Journal of Neurochemistry, Edición 149/1, 2019, Página(s) 12-26, ISSN 0022-3042
Editor: Blackwell Publishing Inc.
DOI: 10.1111/jnc.14601

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Autores: Robert Beattie, Carmen Streicher, Nicole Amberg, Giselle Cheung, Ximena Contreras, Andi H. Hansen, Simon Hippenmeyer
Publicado en: Journal of Visualized Experiments, Edición 159, 2020, ISSN 1940-087X
Editor: MYJoVE Corporation
DOI: 10.3791/61147

A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture

Autores: Alfredo Llorca, Gabriele Ciceri, Robert Beattie, Fong Kuan Wong, Giovanni Diana, Eleni Serafeimidou-Pouliou, Marian Fernández-Otero, Carmen Streicher, Sebastian J Arnold, Martin Meyer, Simon Hippenmeyer, Miguel Maravall, Oscar Marin
Publicado en: eLife, Edición 8, 2019, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.51381

SCOPES: Sparking Curiosity Through Open-Source Platforms in Education and Science

Autores: Robert Beattie, Simon Hippenmeyer, Florian M. Pauler
Publicado en: Frontiers in Education, Edición 5, 2020, ISSN 2504-284X
Editor: Frontiers in Education
DOI: 10.3389/feduc.2020.00048

Imprinted Cdkn1c genomic locus cell-autonomously promotes cell survival in cerebral cortex development

Autores: Susanne Laukoter, Robert Beattie, Florian M. Pauler, Nicole Amberg, Keiichi I. Nakayama, Simon Hippenmeyer
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-14077-2

Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex

Autores: Susanne Laukoter, Florian M. Pauler, Robert Beattie, Nicole Amberg, Andi H. Hansen, Carmen Streicher, Thomas Penz, Christoph Bock, Simon Hippenmeyer
Publicado en: Neuron, Edición 107/6, 2020, Página(s) 1160-1179.e9, ISSN 0896-6273
Editor: Cell Press
DOI: 10.1016/j.neuron.2020.06.031

Genetic mosaic dissection of candidate genes in mice using mosaic analysis with double markers.

Autores: Nicole Amberg; Simon Hippenmeyer
Publicado en: STAR Protocols, Edición 1, 2021, ISSN 2666-1667
Editor: STAR Protocols
DOI: 10.1016/j.xpro.2021.100939

Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped cortical development

Autores: Anderson, Donovan J.; Pauler, Florian; Mckenna, Aaron; Shendure, Jay; Hippenmeyer, Simon; Horwitz, Marshall S.
Publicado en: Cell Systems, 2021, ISSN 2405-4720
Editor: Cell Press
DOI: 10.1016/j.cels.2022.03.006

HepaCAM controls astrocyte self-organization and coupling

Autores: Baldwin KT, Tan CX, Strader ST, Jiang C, Savage JT, Elorza-Vidal X, Contreras X, Rülicke T, Hippenmeyer S, Estévez R, Ji R-R, Eroglu C.
Publicado en: Neuron, 2021, ISSN 1097-4199
Editor: Cell Press
DOI: 10.1016/j.neuron.2021.05.025

Large neutral amino acid levels tune perinatal neuronal excitability and survival

Autores: Lisa S Knaus, Bernadette Basilico, Daniel Malzl, Maria Gerykova Bujalkova, Mateja Smogavec, Lena A Schwarz, Sarah Gorkiewicz, Nicole Amberg, Florian M Pauler, Christian Knittl-Frank, Marianna Tassinari, Nuno Maulide, Thomas Rlicke, Jrg Menche, Simon Hippenmeyer, Gaia Novarino
Publicado en: Cell, 2023, ISSN 0092-8674
Editor: Cell Press
DOI: 10.1016/j.cell.2023.02.037

Other (7)

Reduction of neuronal activity mediated by blood-vessel regression in the brain

Autores: Gao, Xiaofei; Li, Jun-Liszt; Chen, Xingjun; Ci, Bo; Chen, Fei; Lu, Nannan; Shen, Bo; Zheng, Lijun; Jia, Jie-Min; Yi, Yating; Zhang, Shiwen; Shi, Ying-Chao ; Shi, Kaibin ; Propson, Nicholas E ; Huang, Yubin ; Poinsatte, Katherine ; Zhang, Zhaohuan ; Yue, Yuanlei ; Bosco, Dale B ; Lu, Ying-mei ; Yang, Shi-bing ; Adams, Ralf H. ; Lindner, Volkhard ; Huang, Fen ; Wu, Long-Jun ; Zheng, Hui ; Han, Feng
Publicado en: The Preprint Server for Biology, 2020
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.09.15.262782

Simultaneous Identification of Brain Cell Type and Lineage via Single Cell RNA Sequencing

Autores: Anderson DJ, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS
Publicado en: bioRxiv, 2021
Editor: bioRxiv
DOI: 10.1101/2020.12.31.425016

Tissue-wide Genetic and Cellular Landscape Shapes the Execution of Sequential PRC2 Functions in Neural Stem Cell Lineage Progression

Autores: Amberg N, Pauler F, Streicher C, Hippenmeyer S
Publicado en: bioRxiv, 2021
Editor: bioRxiv
DOI: 10.1101/2022.04.04.487003

Heterogeneous progenitor cell behaviors underlie the assembly of neocortical cytoarchitecture

Autores: Alfredo Llorca, Gabriele Ciceri, Robert Beattie, Fong K. Wong, Giovanni Diana, Eleni Serafeimidou, Marian Fernández-Otero, Carmen Streicher, Sebastian J. Arnold, Martin Meyer, Simon Hippenmeyer, Miguel Maravall, Oscar Marín
Publicado en: The Preprint Server for Biology, Edición 494088, 2018
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/494088

Generation of neuronal diversity from common progenitors via Notch signaling in the cerebellum

Autores: Tingting Zhang, Tengyuan Liu, Natalia Mora, Justine Guegan, Mathilde Bertrand, Ximena Contreras, Andi H. Hansen, Carmen Streicher, Marica Anderle, Luca Tiberi, Simon Hippenmeyer, Bassem A. Hassan
Publicado en: The Preprint Server for Biology, 2020
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.03.18.997205

A Genome-wide Library of MADM Mice for Single-Cell Genetic Mosaic Analysis

Autores: Ximena Contreras, Amarbayasgalan Davaatseren, Nicole Amberg, Andi. H. Hansen, Johanna Sonntag, Lill Andersen, Tina Bernthaler, Anna Heger, Randy Johnson, Lindsay A. Schwarz, Liqun Luo, Thomas Rülicke, Simon Hippenmeyer
Publicado en: The Preprint Server for Biology, 2020
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.06.05.136192

GluD2- and Cbln1-mediated Competitive Synaptogenesis Shapes the Dendritic Arbors of Cerebellar Purkinje Cells

Autores: Yukari H. Takeo, Andrew S. Shuster, Linnie Jiang, Miley Hu, David J. Luginbuhl, Thomas Rülicke, Ximena Contreras, Simon Hippenmeyer, Mark J. Wagner, Surya Ganguli, Liqun Luo
Publicado en: The Preprint Server for Biology, 2020
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.06.14.151258