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A study of the roles of the immune and inflammatory systems in hypertension.

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Publications

Epigenetics and Immunometabolism in Diabetes and Aging

Author(s): Tomasz J. Guzik, Francesco Cosentino
Published in: Antioxidants & Redox Signaling, 29/3, 2018, Page(s) 257-274, ISSN 1523-0864
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2017.7299

Heterogenous treatment effects: secrets for a reliable treat-to-target trial?

Author(s): Tomasz J Guzik
Published in: Cardiovascular Research, 113/7, 2017, Page(s) e18-e20, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvx081

When, where, and how to target vascular inflammation in the post-CANTOS era?

Author(s): Pasquale Maffia, Tomasz J Guzik
Published in: European Heart Journal, 2019, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehz133

Involvement of CD8+ T cell subsets in early response to vascular injury in patients with peripheral artery disease in vivo

Author(s): Pawel Maga, Tomasz P. Mikolajczyk, Lukasz Partyka, Mateusz Siedlinski, Mikolaj Maga, Marek Krzanowski, Krzysztof Malinowski, Kevin Luc, Rafal Nizankowski, Deepak L. Bhatt, Tomasz J. Guzik
Published in: Clinical Immunology, 194, 2018, Page(s) 26-33, ISSN 1521-6616
Publisher: Academic Press
DOI: 10.1016/j.clim.2018.06.006

Th1-type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II-dependent hypertension and vascular dysfunction

Author(s): Marta Czesnikiewicz-Guzik, Ryszard Nosalski, Tomasz P Mikolajczyk, Francesca Vidler, Tomasz Dohnal, Elzbieta Dembowska, Delyth Graham, David G Harrison, Tomasz J Guzik
Published in: British Journal of Pharmacology, 2018, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.14536

1,2,3,4,6‐Penta‐ O ‐galloyl‐β‐ d ‐glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II‐induced hypertension

Author(s): Tomasz P. Mikolajczyk, Ryszard Nosalski, Dominik S. Skiba, Joanna Koziol, Magdalena Mazur, Amauri S. Justo‐Junior, Paulina Kowalczyk, Zofia Kusmierczyk, Agata Schramm‐Luc, Kevin Luc, Pasquale Maffia, Delyth Graham, Anna K. Kiss, Marek Naruszewicz, Tomasz J. Guzik
Published in: British Journal of Pharmacology, 2019 Jan 18, 2019, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.14583

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy

Author(s): Marta Czesnikiewicz-Guzik, Grzegorz Osmenda, Mateusz Siedlinski, Richard Nosalski, Piotr Pelka, Daniel Nowakowski, Grzegorz Wilk, Tomasz P Mikolajczyk, Agata Schramm-Luc, Aneta Furtak, Pawel Matusik, Joanna Koziol, Miroslaw Drozdz, Eva Munoz-Aguilera, Maciej Tomaszewski, Evangelos Evangelou, Mark Caulfield, Tomasz Grodzicki, Francesco D'Aiuto, Tomasz J Guzik
Published in: European Heart Journal, 40/42, 2019, Page(s) 3459-3470, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehz646

T-Cell–Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension

Author(s): Ryszard Nosalski, Mateusz Siedlinski, Laura Denby, Eilidh McGinnigle, Michal Nowak, Aurelie Nguyen Dinh Cat, Laura Medina-Ruiz, Marco Cantini, Dominik Skiba, Grzegorz Wilk, Grzegorz Osmenda, Julie Rodor, Manuel Salmeron-Sanchez, Gerard Graham, Pasquale Maffia, Delyth Graham, Andrew H. Baker, Tomasz J. Guzik
Published in: Circulation Research, 126/8, 2020, Page(s) 988-1003, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315428

Cardiovascular Effects of Pharmacological Targeting of Sphingosine Kinase 1

Author(s): Ewelina Józefczuk, Ryszard Nosalski, Blessy Saju, Eva Crespo, Piotr Szczepaniak, Tomasz Jan Guzik, Mateusz Siedlinski
Published in: Hypertension, 75/2, 2020, Page(s) 383-392, ISSN 0194-911X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.119.13450