A study of the roles of the immune and inflammatory systems in hypertension.

Informazioni relative al progetto

InflammaTENSION

ID dell’accordo di sovvenzione: 726318

DOI

10.3030/726318

Progetto chiuso

Data della firma CE 28 Marzo 2017

Data di avvio 1 Maggio 2017

Data di completamento 30 Aprile 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 957 573,75

Contributo UE

€ 1 957 573,75

Coordinato da

THE UNIVERSITY OF EDINBURGH
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (45)

Nox1/4 inhibition exacerbates age dependent perivascular inflammation and fibrosis in a model of spontaneous hypertension. Pharmacol Res. 2020 Nov;161:105235.

Autori: Nosalski R, Mikolajczyk T, Siedlinski M, Saju B, Koziol J, Maffia P, Guzik TJ.
Pubblicato in: Pharmacological Research, Numero 10436618, 2020, Pagina/e 161, 105235, ISSN 1043-6618
Editore: Academic Press
DOI: 10.1016/j.phrs.2020.105235

Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism

Autori: Piotr Szczepaniak, Mateusz Siedlinski, Diana Hodorowicz-Zaniewska, Ryszard Nosalski, Tomasz P. Mikolajczyk, Aneta M. Dobosz, Anna Dikalova, Sergey Dikalov, Joanna Streb, Katarzyna Gara, Pawel Basta, Jaroslaw Krolczyk, Joanna Sulicka-Grodzicka, Ewelina Jozefczuk, Anna Dziewulska, Blessy Saju, Iwona Laksa, Wei Chen, John Dormer, Maciej Tomaszewski, Pasquale Maffia, Marta Czesnikiewicz-Guzik, Filippo
Pubblicato in: Journal of Clinical Investigation, Numero 132, 2023, ISSN 1558-8238
Editore: American Society for Clinical Investigation
DOI: 10.1172/jci149117

Immune mechanisms of hypertension

Autori: Grant R. Drummond, Antony Vinh, Tomasz J. Guzik, Christopher G. Sobey
Pubblicato in: Nature Reviews Immunology, Numero 19, 2023, Pagina/e 517-532, ISSN 1474-1733
Editore: Nature Publishing Group
DOI: 10.1038/s41577-019-0160-5

White Blood Cells and Blood PressureA Mendelian Randomization Study

Autori: Siedlinski M, Jozefczuk E, Xu X, Teumer A, Evangelou E, Schnabel RB, Welsh P, Maffia P, Erdmann J, Tomaszewski M, Caulfield MJ, Sattar N, Holmes MV, Guzik TJ.:
Pubblicato in: Circulation, Numero 00097322, 2020, Pagina/e 141(16):1307-1317, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.119.045102

Significance of sphingosine-1-phosphate in cardiovascular physiology and pathology

Autori: E. Jozefczuk, T.J. Guzik, M. Siedlinski
Pubblicato in: Pharmacological Research, Numero 156, 2022, Pagina/e 104793, ISSN 1043-6618
Editore: Academic Press
DOI: 10.1016/j.phrs.2020.104793

Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis

Autori: James M. Eales, Akhlaq A. Maan, Xiaoguang Xu, Tom Michoel, Pille Hallast, Chiara Batini, Daniel Zadik, Priscilla R. Prestes, Elsa Molina, Matthew Denniff, Juliane Schroeder, Johan L.M. Bjorkegren, John Thompson, Pasquale Maffia, Tomasz J. Guzik, Bernard Keavney, Mark A. Jobling, Nilesh J. Samani, Fadi J. Charchar, Maciej Tomaszewski
Pubblicato in: Arteriosclerosis, Thrombosis, and Vascular Biology, Numero 39, 2024, Pagina/e 2386-2401, ISSN 1079-5642
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.119.312405

Obesity as a cause of kidney disease – insights from Mendelian randomisation studies

Autori: Xiaoguang Xu, James M. Eales, Xiao Jiang, Eleanor Sanderson, David Scannali, Andrew P. Morris, Tomasz J. Guzik, Fadi J. Charchar, Michael V. Holmes, Maciej Tomaszewski
Pubblicato in: Cardiovascular Research, 2022, ISSN 1755-3245
Editore: OUP
DOI: 10.1101/2020.09.13.20155234

Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective.

Autori: Eleanor Murray; Ryszard Nosalski; Ryszard Nosalski; Neil MacRitchie; Maciej Tomaszewski; Maciej Tomaszewski; Pasquale Maffia; Pasquale Maffia; David G. Harrison; Tomasz J. Guzik; Tomasz J. Guzik
Pubblicato in: Cardiovascular Research, Numero 00086363, 2021, Pagina/e 117(13):2589-2609, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab330

Rivaroxaban plus aspirin in obese and overweight patients with vascular disease in the COMPASS trial.

Autori: Guzik TJ., Ramasundarahettige C., Pogosova N., Lopez-Jaramillo P., Dyal L., Berkowitz SD, Muehlhofer E., Bhatt DL., Fox KAA, Yusuf S, Eikelboom JWE:
Pubblicato in: Journal of the American College of Cardiology,, Numero 07351097, 2021, Pagina/e 77(5), pp. 511-525., ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/j.jacc.2020.11.061

T Cells Are Dominant Population in Human Abdominal Aortic Aneurysms and Their Infiltration in the Perivascular Tissue Correlates With Disease Severity

Autori: Agnieszka Sagan, Tomasz P. Mikolajczyk, Wojciech Mrowiecki, Neil MacRitchie, Kevin Daly, Alan Meldrum, Serena Migliarino, Christian Delles, Karol Urbanski, Grzegorz Filip, Boguslaw Kapelak, Pasquale Maffia, Rhian Touyz, Tomasz J. Guzik
Pubblicato in: Frontiers in Immunology, Numero 10, 2019, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2019.01979

Nanoparticle theranostics in cardiovascular inflammation.

Autori: Neil MacRitchie; Valentina Di Francesco; Miguel Ferreira; Tomasz J. Guzik; Tomasz J. Guzik; Paolo Decuzzi; Pasquale Maffia
Pubblicato in: Seminars in Immunology, Numero 10963618, 2021, Pagina/e 56:101536, ISSN 1096-3618
Editore: Academic Press
DOI: 10.1016/j.smim.2021.101536

Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population‐based surveys

Autori: E. Muñoz Aguilera, Y. Leira, Q. Miró Catalina, M. Orlandi, M. Czesnikiewicz‐Guzik, T. J. Guzik, A. D. Hingorani, J. Nart, F. D’Aiuto
Pubblicato in: Journal of Internal Medicine, Numero 289, 2023, Pagina/e 532-546, ISSN 0954-6820
Editore: Blackwell Publishing Inc.
DOI: 10.1111/joim.13180

Neuroimmune cardiovascular interfaces control atherosclerosis

Autori: Sarajo K. Mohanta, Li Peng, Yuanfang Li, Shu Lu, Ting Sun, Lorenzo Carnevale, Marialuisa Perrotta, Zhe Ma, Benjamin Förstera, Karen Stanic, Chuankai Zhang, Xi Zhang, Piotr Szczepaniak, Mariaelvy Bianchini, Borhan R. Saeed, Raimondo Carnevale, Desheng Hu, Ryszard Nosalski, Fabio Pallante, Michael Beer, Donato Santovito, Ali Ertürk, Thomas C. Mettenleiter, Barbara G. Klupp, Remco T. A. Megens, Sab
Pubblicato in: Nature, Numero 605, 2022, Pagina/e 152-159, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-022-04673-6

White Blood Cells and Blood Pressure

Autori: Siedlinski, Mateusz; Jozefczuk, Ewelina; Xu, Xiaoguang; Teumer, Alexander; Evangelou, Evangelos; Schnabel, Renate B.; Welsh, Paul; Maffia, Pasquale; Erdmann, Jeanette; Tomaszewski, Maciej; Caulfield, Mark J.; Sattar, Naveed; Holmes, Michael V.; Guzik, Tomasz J.
Pubblicato in: Circulation, Numero 5, 2020, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.

Inflammatory Signature of Human Hypertension: From Regulatory to Exhausted T Cells.

Autori: Mikolajczyk, Tomasz P.; Guzik, Tomasz J.
Pubblicato in: JACC Basic Transl Sci, Numero 1, 2023, ISSN 2452-302X
Editore: Elsevier

Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

Autori: Mateusz Siedlinski, Lorenzo Carnevale, Xiaoguang Xu, Daniela Carnevale, Evangelos Evangelou, Mark J Caulfield, Pasquale Maffia, Joanna Wardlaw, Nilesh J Samani, Maciej Tomaszewski, Giuseppe Lembo, Michael V Holmes, Tomasz J Guzik
Pubblicato in: European Heart Journal, Numero 44, 2023, Pagina/e 2114-2125, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehad101

Vascular phenotypes in early hypertension

Autori: Eleanor C. Murray, Christian Delles, Patryk Orzechowski, Pawel Renc, Arkadiusz Sitek, Joost Wagenaar, Tomasz J. Guzik
Pubblicato in: Journal of Human Hypertension, Numero 37, 2023, Pagina/e 898-906, ISSN 1476-5527
Editore: Springer - Nature
DOI: 10.1038/s41371-022-00794-7

GLUT-1/PKM2 loop dysregulation in patients with non-ST-segment elevation myocardial infarction promotes metainflammation

Autori: Francesco Canonico, Daniela Pedicino, Anna Severino, Ramona Vinci, Davide Flego, Eugenia Pisano, Alessia d’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Astrid De Ciutiis, Sara Russo, Marianna Di Sario, Giulia Angelini, Piotr Szczepaniak, Alfonso Baldi, Boguslaw Kapelak, Karol Wierzbicki, Rocco A Montone, Domenico D’Amario, Massimo Massetti, Tomasz J Guzik, Filippo Crea, Giovanna Li
Pubblicato in: Cardiovascular Research, Numero 119, 2023, Pagina/e 2653-2662, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvac184

Role of inflammatory chemokines in hypertension

Autori: Tomasz Mikolajczyk; Piotr Szczepaniak; Francesca Vidler; Pasquale Maffia; Gerard J. Graham; Tomasz J. Guzik; Tomasz J. Guzik
Pubblicato in: Jaournal Of Pharmacology and Therapeutics, Numero 01637258, 2021, Pagina/e 223, July 2021, 107799, ISSN 0163-7258
Editore: Pergamon Press
DOI: 10.1016/j.pharmthera.2020.107799

Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomised trials

Autori: Elisabetta Caiazzo, Asma O.M. Rezig, Dario Bruzzese, Armando Ialenti, Carla Cicala, John G.F. Cleland, Tomasz J. Guzik, Pasquale Maffia, Pierpaolo Pellicori
Pubblicato in: Pharmacological Research, Numero 176, 2023, Pagina/e 106053, ISSN 1043-6618
Editore: Academic Press
DOI: 10.1016/j.phrs.2021.106053

COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options.

Autori: Tomasz J. Guzik; Tomasz J. Guzik; Saidi A Mohiddin; Anthony Dimarco; Vimal Patel; K Savvatis; Federica M. Marelli-Berg; Meena S. Madhur; Maciej Tomaszewski; Pasquale Maffia; Pasquale Maffia; Fulvio D'Acquisto; Stuart A. Nicklin; Ali J. Marian; Ryszard Nosalski; Ryszard Nosalski; Eleanor Murray; Bartłomiej Guzik; Colin Berry; Rhian M. Touyz; Reinhold Kreutz; Dao Wen Wang; David Bhella; Orlando Sag
Pubblicato in: Cardiovascular Research, Numero 14, 2020, Pagina/e 1755-3245, ISSN 1755-3245
Editore: OXFORD UNIVERSITY PRESS
DOI: 10.1093/cvr/cvaa106

Monocytes M( <i>MP</i> )aking Way for T-Cell Vascular Infiltration

Autori: Ryszard Nosalski, Pasquale Maffia, Tomasz J. Guzik
Pubblicato in: Circulation Research, Numero 123, 2024, Pagina/e 638-640, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.118.313668

Molecular imaging of cardiovascular inflammation.

Autori: MacRitchie, N., Noonan, J., Guzik, T. J. and Maffia, P.
Pubblicato in: British Journal of Pharmacology,, Numero 00071188, 2021, Pagina/e 178(21), pp. 4216-4245, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.15654

Epigenetics and Immunometabolism in Diabetes and Aging

Autori: Tomasz J. Guzik, Francesco Cosentino
Pubblicato in: Antioxidants & Redox Signaling, Numero 29/3, 2018, Pagina/e 257-274, ISSN 1523-0864
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2017.7299

Heterogenous treatment effects: secrets for a reliable treat-to-target trial?

Autori: Tomasz J Guzik
Pubblicato in: Cardiovascular Research, Numero 113/7, 2017, Pagina/e e18-e20, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvx081

When, where, and how to target vascular inflammation in the post-CANTOS era?

Autori: Pasquale Maffia, Tomasz J Guzik
Pubblicato in: European Heart Journal, 2019, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehz133

Involvement of CD8+ T cell subsets in early response to vascular injury in patients with peripheral artery disease in vivo

Autori: Pawel Maga, Tomasz P. Mikolajczyk, Lukasz Partyka, Mateusz Siedlinski, Mikolaj Maga, Marek Krzanowski, Krzysztof Malinowski, Kevin Luc, Rafal Nizankowski, Deepak L. Bhatt, Tomasz J. Guzik
Pubblicato in: Clinical Immunology, Numero 194, 2018, Pagina/e 26-33, ISSN 1521-6616
Editore: Academic Press
DOI: 10.1016/j.clim.2018.06.006

Th1-type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II-dependent hypertension and vascular dysfunction

Autori: Marta Czesnikiewicz-Guzik, Ryszard Nosalski, Tomasz P Mikolajczyk, Francesca Vidler, Tomasz Dohnal, Elzbieta Dembowska, Delyth Graham, David G Harrison, Tomasz J Guzik
Pubblicato in: British Journal of Pharmacology, 2018, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.14536

1,2,3,4,6‐Penta‐ O ‐galloyl‐β‐ d ‐glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II‐induced hypertension

Autori: Tomasz P. Mikolajczyk, Ryszard Nosalski, Dominik S. Skiba, Joanna Koziol, Magdalena Mazur, Amauri S. Justo‐Junior, Paulina Kowalczyk, Zofia Kusmierczyk, Agata Schramm‐Luc, Kevin Luc, Pasquale Maffia, Delyth Graham, Anna K. Kiss, Marek Naruszewicz, Tomasz J. Guzik
Pubblicato in: British Journal of Pharmacology, Numero 2019 Jan 18, 2019, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.14583

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy

Autori: Marta Czesnikiewicz-Guzik, Grzegorz Osmenda, Mateusz Siedlinski, Richard Nosalski, Piotr Pelka, Daniel Nowakowski, Grzegorz Wilk, Tomasz P Mikolajczyk, Agata Schramm-Luc, Aneta Furtak, Pawel Matusik, Joanna Koziol, Miroslaw Drozdz, Eva Munoz-Aguilera, Maciej Tomaszewski, Evangelos Evangelou, Mark Caulfield, Tomasz Grodzicki, Francesco D'Aiuto, Tomasz J Guzik
Pubblicato in: European Heart Journal, Numero 40/42, 2019, Pagina/e 3459-3470, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehz646

T-Cell–Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension

Autori: Ryszard Nosalski, Mateusz Siedlinski, Laura Denby, Eilidh McGinnigle, Michal Nowak, Aurelie Nguyen Dinh Cat, Laura Medina-Ruiz, Marco Cantini, Dominik Skiba, Grzegorz Wilk, Grzegorz Osmenda, Julie Rodor, Manuel Salmeron-Sanchez, Gerard Graham, Pasquale Maffia, Delyth Graham, Andrew H. Baker, Tomasz J. Guzik
Pubblicato in: Circulation Research, Numero 126/8, 2020, Pagina/e 988-1003, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315428

Cardiovascular Effects of Pharmacological Targeting of Sphingosine Kinase 1

Autori: Ewelina Józefczuk, Ryszard Nosalski, Blessy Saju, Eva Crespo, Piotr Szczepaniak, Tomasz Jan Guzik, Mateusz Siedlinski
Pubblicato in: Hypertension, Numero 75/2, 2020, Pagina/e 383-392, ISSN 0194-911X
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.119.13450

Why do some asthma patients respond poorly to glucocorticoid therapy?

Autori: Ishbel Henderson, Elisabetta Caiazzo, Charles McSharry, Tomasz J. Guzik, Pasquale Maffia
Pubblicato in: Pharmacological Research, Numero 160, 2022, Pagina/e 105189, ISSN 1043-6618
Editore: Academic Press
DOI: 10.1016/j.phrs.2020.105189

Cytokines at the Interplay Between Asthma and Atherosclerosis?

Autori: Danila Gurgone, Lucy McShane, Charles McSharry, Tomasz J. Guzik, Pasquale Maffia
Pubblicato in: Frontiers in Pharmacology, Numero 11, 2020, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00166

Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions

Autori: Nicola Riccardo Pugliese, Pierpaolo Pellicori, Francesco Filidei, Nicolò De Biase, Pasquale Maffia, Tomasz J Guzik, Stefano Masi, Stefano Taddei, John G F Cleland
Pubblicato in: Cardiovascular Research, Numero 118, 2023, Pagina/e 3536-3555, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvac133

Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.

Autori: 3. Eales JM, Jiang X, Xu X, Saluja S, Akbarov A, Cano-Gamez E, McNulty MT, Finan C, Guo H, Wystrychowski W, Szulinska M, Thomas H, Pramanik S, Chopade S, Prestes P, Wise I, Evangelou E, Salehi M, Shakanti Y, Ekholm M, Denniff M, Nazgiewicz A, Eichinger F, Godfrey B, Antczak A, Glyda M, Król R, Eyre S, Brown J, Berzuini C, Bowes J, Caulfield M, Zukowska-Szczechowska E, Zywiec J, Bogdanski P, Kret
Pubblicato in: Nature Genetics, Numero 12, 2021, Pagina/e 53(5), pp. 630-637., ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-021-00835-w

JCAD: a new GWAS target to reduce residual cardiovascular risk?

Autori: Tomasz J Guzik, Keith M Channon
Pubblicato in: European Heart Journal, Numero 44, 2023, Pagina/e 1834-1836, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehac708

Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications

Autori: Maciej Tomaszewski, Andrew P. Morris, Joanna M.M. Howson, Nora Franceschini, James M. Eales, Xiaoguang Xu, Sergey Dikalov, Tomasz J. Guzik, Benjamin D. Humphreys, Stephen Harrap, Fadi J. Charchar
Pubblicato in: Kidney International, Numero 102, 2024, Pagina/e 492-505, ISSN 0085-2538
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2022.04.045

Sex-specific relationships of inflammatory biomarkers with blood pressure in older adults

Autori: Joanna Sulicka-Grodzicka, Barbara Wizner, Tomasz Zdrojewski, Małgorzata Mossakowska, Monika Puzianowska-Kuźnicka, Jerzy Chudek, Andrzej Więcek, Mariusz Korkosz, Elisabetta Caiazzo, Pasquale Maffia, Mateusz Siedlinski, Franz H. Messerli, Tomasz J. Guzik
Pubblicato in: GeroScience, Numero 46, 2024, Pagina/e 4603-4614, ISSN 2509-2723
Editore: Springer
DOI: 10.1007/s11357-024-01170-8

Immune and inflammatory mechanisms in hypertension

Autori: Tomasz J. Guzik, Ryszard Nosalski, Pasquale Maffia, Grant R. Drummond
Pubblicato in: Nature Reviews Cardiology, Numero 21, 2024, Pagina/e 396-416, ISSN 1759-5002
Editore: Nature Publishing Group
DOI: 10.1038/s41569-023-00964-1

Contributions of obesity to kidney health and disease: insights from Mendelian randomization and the human kidney transcriptomics

Autori: Xiaoguang Xu, James M Eales, Xiao Jiang, Eleanor Sanderson, Maciej Drzal, Sushant Saluja, David Scannali, Bryan Williams, Andrew P Morris, Tomasz J Guzik, Fadi J Charchar, Michael V Holmes, Maciej Tomaszewski
Pubblicato in: Cardiovascular Research, Numero 118, 2022, Pagina/e 3151-3161, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab357

The importance of microvascular inflammation in ageing and age-related diseases: a position paper from the ESH working group on small arteries, section of microvascular inflammation

Autori: Alessandro Mengozzi, Carolina de Ciuceis, Raffaella Dell’oro, Georgios Georgiopoulos, Antonios Lazaridis, Ryszard Nosalski, George Pavlidis, Simon Tual-Chalot, Claudia Agabiti-Rosei, Panagiota Anyfanti, Livia L. Camargo, Edyta Dąbrowska, Fosca Quarti-Trevano, Marcin Hellmann, Stefano Masi, Georgios Mavraganis, Augusto C. Montezano, Francesco J. Rios, Pawel J. Winklewski, Jacek Wolf, Sarah Costa
Pubblicato in: Journal of Hypertension, Numero 41, 2024, Pagina/e 1521-1543, ISSN 0263-6352
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/hjh.0000000000003503

Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney.

Autori: Jiang X, Eales JM, Scannali D, Nazgiewicz A, Prestes P, Maier M, Denniff M, Xu X, Saluja S, Cano-Gamez E, Wystrychowski W, Szulinska M, Antczak A, Byars S, Skrypnik D, Glyda M, Król R, Zywiec J, Zukowska-Szczechowska E, Burrell LM, Woolf AS, Greenstein A, Bogdanski P, Keavney B, Morris AP, Heagerty A, Williams B, Harrap SB, Trynka G, Samani NJ, Guzik TJ, Charchar FJ, Tomaszewski M.:
Pubblicato in: Eur Heart J, Numero 56, 2020, Pagina/e 4580-4588, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehaa794

Hypertension: Focus on autoimmunity and oxidative stress

Autori: Heather Y. Small, Serena Migliarino, Marta Czesnikiewicz-Guzik, Tomasz J. Guzik
Pubblicato in: Free Radical Biology and Medicine, Numero 125, 2024, Pagina/e 104-115, ISSN 0891-5849
Editore: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.05.085

Skin sodium, lymphatics, and blood pressure: a non-canonical mechanism of salt-sensitive hypertension

Autori: Ryszard Nosalski, Tomasz J Guzik
Pubblicato in: European Heart Journal, Numero 44, 2023, Pagina/e 2743-2745, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehad290