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Smart optical and ultrasound diagnostics of breast cancer

Objective

SOLUS is a trans-disciplinary 54-month project bringing together 9 partners: industries (4), academic and clinical institutions from 5 countries (engineers, physicists and radiologists) representing cutting-edge expertise in their fields, to develop an innovative non-invasive, point-of-care, low-cost, easy-to-operate, multi-modal imaging system (diffuse optics and ultrasounds/shear wave elastography) for high-specificity diagnosis of breast cancer, the most common female cancer in Europe. Mammographic screening is effective in reducing mortality, however the 10-year cumulative false-positive risk is 50-60%, leading to needless additional invasive procedures (e.g. biopsy). The project addresses the unmet clinical need for higher specificity in breast cancer imaging following screening by fully combining photonics with non-photonics techniques, developing and clinically validating innovative and previously unthinkable photonics concepts and components: time-domain small source-detector distance optical tomography, miniaturized picosecond pulsed laser sources, high-dynamic-range time-gated single-photons detectors to achieve unprecedented sensitivity and depth penetration. For the first time, this allows a comprehensive quantitative characterization of breast tissue including composition (water, lipids, collagen), functional blood parameters, morphologic information and mechanical parameters (stiffness). This innovative multi-parametric characterization will significantly improve the specificity of breast screening, with great impact on the quality of life of millions of European women every year, and huge savings for the healthcare systems. The strong involvement of leading industrial players at all levels in the value chain will push the European innovation process and make a significant contribution to ensuring Europe’s industrial leadership in the biophotonics healthcare market, while addressing one of the largest societal challenges in health and well-being.

Call for proposal

H2020-ICT-2016-1
See other projects for this call

Coordinator

POLITECNICO DI MILANO
Address
Piazza Leonardo Da Vinci 32
20133 Milano
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 726 988,75

Participants (8)

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
EU contribution
€ 518 783,75
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
SUPERSONIC IMAGINE
France
EU contribution
€ 407 500
Address
510 Rue Rene Descartes Les Jardins De La Duranne B Et Bat F
13857 Aix En Provence
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VERMON SA
France
EU contribution
€ 555 312,50
Address
67 Rue Fromentel
37000 Tours
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 300 213,75
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
MICRO PHOTON DEVICES SRL
Italy
EU contribution
€ 400 711,25
Address
Via Waltraud Gebert Deeg 3/F
39100 Bolzano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OSPEDALE SAN RAFFAELE SRL
Italy
EU contribution
€ 212 500
Address
Via Olgettina 60
20132 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG
Austria
EU contribution
€ 366 250
Address
Am Gestade 1
1010 Wien
Activity type
Research Organisations
IC-HAUS GMBH
Germany
EU contribution
€ 327 000
Address
Am Kuemmerling 18
55294 Bodenheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)