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Smart optical and ultrasound diagnostics of breast cancer

Objetivo

SOLUS is a trans-disciplinary 54-month project bringing together 9 partners: industries (4), academic and clinical institutions from 5 countries (engineers, physicists and radiologists) representing cutting-edge expertise in their fields, to develop an innovative non-invasive, point-of-care, low-cost, easy-to-operate, multi-modal imaging system (diffuse optics and ultrasounds/shear wave elastography) for high-specificity diagnosis of breast cancer, the most common female cancer in Europe. Mammographic screening is effective in reducing mortality, however the 10-year cumulative false-positive risk is 50-60%, leading to needless additional invasive procedures (e.g. biopsy). The project addresses the unmet clinical need for higher specificity in breast cancer imaging following screening by fully combining photonics with non-photonics techniques, developing and clinically validating innovative and previously unthinkable photonics concepts and components: time-domain small source-detector distance optical tomography, miniaturized picosecond pulsed laser sources, high-dynamic-range time-gated single-photons detectors to achieve unprecedented sensitivity and depth penetration. For the first time, this allows a comprehensive quantitative characterization of breast tissue including composition (water, lipids, collagen), functional blood parameters, morphologic information and mechanical parameters (stiffness). This innovative multi-parametric characterization will significantly improve the specificity of breast screening, with great impact on the quality of life of millions of European women every year, and huge savings for the healthcare systems. The strong involvement of leading industrial players at all levels in the value chain will push the European innovation process and make a significant contribution to ensuring Europe’s industrial leadership in the biophotonics healthcare market, while addressing one of the largest societal challenges in health and well-being.

Ámbito científico

  • /ciencias naturales/informática y ciencias de la información/software/software de sistemas
  • /ciencias sociales/sociología/demografía/mortalidad
  • /ciencias naturales/ciencias físicas/óptica/física del láser/láseres pulsados
  • /ciencias médicas y de la salud/medicina clínica/radiología/imagen médica
  • /ciencias naturales/informática y ciencias de la información/internet/internet de las cosas
  • /ciencias médicas y de la salud/medicina clínica/oncología/cáncer/cáncer de mama
  • /ciencias naturales/ciencias físicas/acústica/ultrasonido
  • /ciencias naturales/ciencias físicas/física nuclear

Convocatoria de propuestas

H2020-ICT-2016-1
Consulte otros proyectos de esta convocatoria

Régimen de financiación

RIA - Research and Innovation action

Coordinador

POLITECNICO DI MILANO
Dirección
Piazza Leonardo Da Vinci 32
20133 Milano
Italia
Tipo de actividad
Higher or Secondary Education Establishments
Aportación de la UE
€ 726 988,75

Participantes (8)

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Francia
Aportación de la UE
€ 518 783,75
Dirección
Rue Leblanc 25
75015 Paris 15
Tipo de actividad
Research Organisations
SUPERSONIC IMAGINE
Francia
Aportación de la UE
€ 407 500
Dirección
510 Rue Rene Descartes Les Jardins De La Duranne B Et Bat F
13857 Aix En Provence
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VERMON SA
Francia
Aportación de la UE
€ 555 312,50
Dirección
Rue General Renault 180
37000 Tours
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITY COLLEGE LONDON
United Kingdom
Aportación de la UE
€ 300 213,75
Dirección
Gower Street
WC1E 6BT London
Tipo de actividad
Higher or Secondary Education Establishments
MICRO PHOTON DEVICES SRL
Italia
Aportación de la UE
€ 400 711,25
Dirección
Via Waltraud Gebert Deeg 3/F
39100 Bolzano
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OSPEDALE SAN RAFFAELE SRL
Italia
Aportación de la UE
€ 212 500
Dirección
Via Olgettina 60
20132 Milano
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EIBIR GEMEINNUTZIGE GMBH ZUR FORDERUNG DER ERFORSCHUNG DER BIOMEDIZINISCHEN BILDGEBUNG
Austria
Aportación de la UE
€ 366 250
Dirección
Am Gestade 1
1010 Wien
Tipo de actividad
Research Organisations
IC-HAUS GMBH
Alemania
Aportación de la UE
€ 327 000
Dirección
Am Kuemmerling 18
55294 Bodenheim
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)