Deliverables
Discrete electronics ASICs data management and packaging developments to integrate the developed large area neural interfaces with multiplexed channels into electrophysiological recording systems using wireless communication
Characterization of inner speech signalsThis deliverable will provide an exhaustive neuroanatomical and neurophysiological description of inner speech signals which will ultimately contribute to optimize neural decoding of inner speech
Initial evaluation of the newly developed technologyFunctionality of the implants and ASIC as well as biocompatibility will be tested in freely moving animals.
Functional plasticity of speech using neurofeedbackThis deliverable will describe whether and how inner speech production systems can use neurofeedback to reorganize and improve speech synthesis
Multiplexed surface conformal µECoGPrototype and report of prototype assessment. The prototype will integrate the developed capabilities of multiplexing technology and the novel µECoG designs. The report will assess the device performance in terms of number of active sites, site dimension, electronic noise, and maximum sampling frequency.
Report on novel cortical µECoG and intracortical technologiesReport on the performance of non-multiplexed µECoG surface probes and intracortical devices based on graphene field-effect transistors and PEDOT:PSS organic-electrochemical transistors and electrodes. Benchmarking with competing technologies (metal electrode arrays).
System integration of first multiplexed neural interfaces with digital outputDiscrete electronics, ASIC, data management and packaging developments to integrate the developed small area neural interfaces with frequency-domain multiple access (FDMA) multiplexing technique of up to 8x8 recording sites into electrophysiological recording systems. This first ASIC also includes the A/D conversion of all the multiplexed channels but not any digital post-processing oriented to data compression. This deliverable improves the initial description of D2.1 by introducing a novel continuous-time multiplexing capability, whose number of channels can be up-scaled in the subsequent deliverables.
System integration of scaled multiplexed neural interfaces with digital signal processingDiscrete electronics ASIC data management and packaging developments to integrate the developed large area neural interfaces with frequencydomain multiplexing FDM or timedomain multiplexing TDM of up to 32x32 1024 recording sites and digital postprocessing for data compression into electrophysiological recording systems This deliverable improves the initial description of D22 by scaling up the number of recording channels and by developing two candidate technologies for multiplexing in order to increase the possibility of success
Dissemination materials and eventsBest ethical practice guidelines for clinicians information pack for device regulators public event at science museums
A series 68 of academic publications on ethical issues as indicated above
Publications
Author(s):
Han S, Polyravas AG, Wustoni S, Inal S, Malliaras GG
Published in:
Advanced Materials Technologies, Issue 2021-08-19, 2021, Page(s) 6, 2100763, ISSN 2365-709X
Publisher:
Wiley VCH
DOI:
10.1002/admt.202100763
Author(s):
Amy E. Rochford, Alejandro Carnicer‐Lombarte, Vincenzo F. Curto, George G. Malliaras, Damiano G. Barone
Published in:
Advanced Materials, Issue 32/15, 2020, Page(s) 1903182, ISSN 0935-9648
Publisher:
United Nations Industrial Developement Organization
DOI:
10.1002/adma.201903182
Author(s):
Stephen Rainey, Kevin McGillivray, Simi Akintoye, Tyr Fothergill, Christoph Bublitz, Bernd Stahl
Published in:
Journal of Law and the Biosciences, Issue Journal of law and the Biosciences, 2020, Page(s) 1-19, ISSN 2053-9711
Publisher:
Oxford University Press
DOI:
10.1093/jlb/lsaa051
Author(s):
Erez Shor; Pedro Herrero-Vidal; Adam Dewan; Ilke Uguz; Vincenzo F. Curto; George G. Malliaras; Cristina Savin; Thomas Bozza; Dmitry Rinberg
Published in:
Biosensors and Bioelectronics, Issue 28/09/2021, 2021, ISSN 0956-5663
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.bios.2021.113664
Author(s):
Stephen Rainey, Hannah Maslen, Julian Savulescu
Published in:
AJOB Neuroscience, Issue 11/1, 2020, Page(s) 46-58, ISSN 2150-7740
Publisher:
Taylor and Francis
DOI:
10.1080/21507740.2019.1704918
Author(s):
Middya S, Curto VF, Fernández-Villegas A, Robbins M, Gurke J, Moonen EJM, Kaminski Schierle GS, Malliaras GG
Published in:
Advanced Science, Issue 2021-05-11, 2021, Page(s) 8, 2004434, ISSN 2198-3844
Publisher:
Wiley VCH
DOI:
10.1002/advs.202004434
Author(s):
Javier Martínez-Aguilar; Javier Martínez-Aguilar; Sara Santiago; Anton Sirota; Ramon Garcia-Cortadella; Ramon Garcia-Cortadella; Clement Hébert; Rosa Villa; Rosa Villa; Anton Guimerà-Brunet; Anton Guimerà-Brunet; Gonzalo Guirado; Jose A. Garrido; Xavi Illa; Xavi Illa; Ana Moya Lara; Ana Moya Lara; Gerrit Schwesig; Nathan Schaefer; Nathan Schaefer
Published in:
2D Materials, Issue Vol 7, Issue 2, 2020, ISSN 2053-1583
Publisher:
IOP Publishing Ltd
DOI:
10.1088/2053-1583/ab7976
Author(s):
R.M. Santos, A. Sirota.
Published in:
Feb 15, 2021, 2021, Page(s) 10:e61940, ISSN 2050-084X
Publisher:
eLife Sciences Publications
DOI:
10.7554/elife.61940
Author(s):
Stephen Rainey, Yasemin J. Erden
Published in:
Science and Engineering Ethics, Issue 26/5, 2020, Page(s) 2439-2454, ISSN 1353-3452
Publisher:
Opragen Publications
DOI:
10.1007/s11948-020-00240-2
Author(s):
Eric Fourneret, Blaise Yvert
Published in:
Frontiers in Artificial Intelligence, Issue 3, 2020, ISSN 2624-8212
Publisher:
Frontiers Media SA
DOI:
10.3389/frai.2020.00027
Author(s):
Eduard Masvidal-Codina, Trevor M Smith, Daman Rathore, Yunan Gao, Xavi Illa, Elisabet Prats-Alfonso, Elena Del Corro, Andrea Bonaccini Calia, Gemma Rius, Iñigo Martin-Fernandez, Christoph Guger, Patrick Reitner, Rosa Villa, Jose A Garrido, Anton Guimerà-Brunet, Rob C Wykes
Published in:
Journal of Neural Engineering, Issue 18/5, 2021, Page(s) 055002, ISSN 1741-2560
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1741-2552/abecf3
Author(s):
Palma M, Khoshnevis M, Lion M, Zenga C, Kefs S, Fallegger F, Gabelle Flandin I, Lacour S, Yvert B
Published in:
J Neurosci Meths, Issue 15 Jan 2022, 2022, Page(s) 366: 109427, ISSN 3397-7054
Publisher:
Elsevier
DOI:
10.1016/j.jneumeth.2021.109427
Author(s):
Ramon Garcia-Cortadella, Nathan Schäfer, Jose Cisneros-Fernandez, Lucia Ré, Xavi Illa, Gerrit Schwesig, Ana Moya, Sara Santiago, Gonzalo Guirado, Rosa Villa, Anton Sirota, Francesc Serra-Graells, Jose A. Garrido, Anton Guimerà-Brunet
Published in:
Nano Letters, Issue 20/5, 2020, Page(s) 3528-3537, ISSN 1530-6984
Publisher:
American Chemical Society
DOI:
10.1021/acs.nanolett.0c00467
Author(s):
Stephen Rainey, Jan Christoph Bublitz, Hannah Maslen, Hannah Thornton
Published in:
AJOB Neuroscience, Issue 10/4, 2019, Page(s) 180-182, ISSN 2150-7740
Publisher:
Taylor and Francis
DOI:
10.1080/21507740.2019.1665134
Author(s):
N. Karalis, A. Sirota
Published in:
24/01/2022, 2021, Page(s) 13, 467, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-022-28090-5
Author(s):
STEPHEN RAINEY, HANNAH MASLEN, PIERRE MÉGEVAND, LUC H. ARNAL, ERIC FOURNERET, BLAISE YVERT
Published in:
Cambridge Quarterly of Healthcare Ethics, Issue 28/04, 2019, Page(s) 657-670, ISSN 0963-1801
Publisher:
Cambridge University Press
DOI:
10.1017/s0963180119000604
Author(s):
Hannah Maslen, Stephen Rainey
Published in:
Philosophy & Technology, 2020, ISSN 2210-5433
Publisher:
Springer Verlag
DOI:
10.1007/s13347-019-00389-0
Author(s):
Stephen Rainey; Pierre Mégevand; Eric Fourneret; Andy Christen; Stephanie Martin
Published in:
Science and Engineering Ethics, Issue 26, 2020, Page(s) 2295–2311, ISSN 1353-3452
Publisher:
Opragen Publications
DOI:
10.1007/s11948-020-00218-0
Author(s):
Cisneros-Fernández, J.; Guimerà-Brunet, Anton; Garcia Cortadella, Ramon; Schäfer, Nathan; Garrido, Jose A.; Terés, Lluís; Serra-Graells, Francesc
Published in:
IEEE Transactions on Biomedical Circuits and Systems, Issue October 2021, 2021, ISSN 1932-4545
Publisher:
Institute of Electrical and Electronics Engineers
DOI:
10.1109/tbcas.2021.3113556
Author(s):
Christian M. Schaefer, José M. Caicedo Roque, Guillaume Sauthier, Jessica Bousquet, Clément Hébert, Justin R. Sperling, Amador Pérez-Tomás, José Santiso, Elena del Corro, Jose A. Garrido
Published in:
Chemistry of Materials, 2021, ISSN 0897-4756
Publisher:
American Chemical Society
DOI:
10.1021/acs.chemmater.1c00646
Author(s):
Ramon Garcia Cortadella; Nikolaos Mavredakis; Jose A. Garrido; Andrea Bonaccini Calia; Henri Happy; D. Vignaud; David Jiménez; Emiliano Pallecchi; W. Wei
Published in:
Applied Electronic Materials, Issue Vol 1, Issue 12, 2019, Page(s) 2626-2636, ISSN 2637-6113
Publisher:
American Chemical Society
DOI:
10.1021/acsaelm.9b00604
Author(s):
Anton Guimerà-Brunet; Eduard Masvidal-Codina; Jose Cisneros-Fernandez; Francesc Serra-Graells; Jose A. Garrido
Published in:
Current Opinion in Biotechnology, Issue December 2021, 2021, ISSN 1879-0429
Publisher:
Elsevier
DOI:
10.1016/j.copbio.2021.10.002
Author(s):
Nathan Schaefer; Anton Guimerà-Brunet; Andrea Bonaccini Calia; George G. Malliaras; Jose A. Garrido; Anastasios G. Polyravas; Vincenzo F. Curto
Published in:
Flexible and Printed Electronics, Issue 4, 2019, Page(s) 044003, ISSN 2058-8585
Publisher:
IOP
DOI:
10.17863/cam.44933
Author(s):
Florent Bocquelet, Thomas Hueber, Laurent Girin, Stéphan Chabardès, Blaise Yvert
Published in:
Journal of Physiology-Paris, Issue 110/4, 2016, Page(s) 392-401, ISSN 0928-4257
Publisher:
Elsevier BV
DOI:
10.1016/j.jphysparis.2017.07.002
Author(s):
Masvidal Codina, Eduard; Illa Vila, Xavier; Dasilva, Miguel; Bonaccini Calia, Andrea; Dragojević, Tanja; Vidal Rosas, Ernesto E.; Prats Alfonso, Elisabet; Martínez Aguilar, Javier; De la Cruz Sánchez, José M.; Garcia Cortadella, Ramon; Godignon, Philippe; Rius Suñé, Gemma; Camassa, Alessandra; Del Corro Garcia, Elena; Bousquet, Jessica; Hébert, Clement; Durduran, Turgut; Villa, Rosa; Sánch
Published in:
Nature Materials, Issue 18, 2019, Page(s) 280–288, ISSN 1476-1122
Publisher:
Nature Publishing Group
DOI:
10.1038/s41563-018-0249-4
Author(s):
Jonathan Rivnay, Sahika Inal, Alberto Salleo, Róisín M. Owens, Magnus Berggren, George G. Malliaras
Published in:
Nature Reviews Materials, Issue 3/2, 2018, Page(s) 17086, ISSN 2058-8437
Publisher:
Nature Research (Springer Nature)
DOI:
10.1038/natrevmats.2017.86
Author(s):
Jolien Pas, Alexandra L Rutz, Pascale P Quilichini, Andrea Slézia, Antoine Ghestem, Attila Kaszas, Mary J Donahue, Vincenzo F Curto, Rodney P O’Connor, Christophe Bernard, Adam Williamson, George G Malliaras
Published in:
Journal of Neural Engineering, Issue 15/6, 2018, Page(s) 065001, ISSN 1741-2560
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1741-2552/aadc1d
Author(s):
Stephen Rainey
Published in:
Journal of law and medicine, Issue 26, 2018, Page(s) 44-53, ISSN 1320-159X
Publisher:
Lawbook Co.
DOI:
10.5281/zenodo.2535459
Author(s):
Bijan Pesaran, Martin Vinck, Gaute T. Einevoll, Anton Sirota, Pascal Fries, Markus Siegel, Wilson Truccolo, Charles E. Schroeder, Ramesh Srinivasan
Published in:
Nature Neuroscience, Issue 21/7, 2018, Page(s) 903-919, ISSN 1097-6256
Publisher:
Nature Publishing Group
DOI:
10.1038/s41593-018-0171-8
Author(s):
Marie Bernert, Blaise Yvert
Published in:
International Journal of Neural Systems, Issue 29, 2019, Page(s) 1850059, ISSN 0129-0657
Publisher:
World Scientific Publishing Co
DOI:
10.1142/s0129065718500594
Author(s):
Jaime Delgado Saa, Andy Christen, Stephanie Martin, Brian N. Pasley, Robert T. Knight, Anne-Lise Giraud
Published in:
Scientific Reports, Issue 10/1, 2020, Page(s) 7637, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-020-63303-1
Author(s):
Jose Manuel de la Cruz; Jessica Bousquet; Clement Hébert; Ramon Garcia-Cortadella; Ramon Garcia-Cortadella; Anton Guimerà-Brunet; Anton Guimerà-Brunet; Nikolaos Mavredakis; Rosa Villa; Rosa Villa; Andrea Bonaccini Calia; Andrea Bonaccini Calia; David Jiménez; Laura Rodríguez; Jose A. Garrido; Javier Martínez-Aguilar; Javier Martínez-Aguilar; Xavi Illa; Xavi Illa; Nathan Schaefer; Nathan Sch
Published in:
Carbon, Issue Vol 161, 2020, Page(s) 647-655, ISSN 0008-6223
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.carbon.2020.01.066
Author(s):
Maria V. Sanchez-Vives; Christoph Jeschke; Anton Guimerà; Anton Guimerà; Javier Martínez-Aguilar; Javier Martínez-Aguilar; Nathan Schäfer; Anton Sirota; Jose Manuel de la Cruz; Xavi Illa; Xavi Illa; Rosa Villa; Rosa Villa; Ramon Garcia-Cortadella; Jose A. Garrido; Eduard Masvidal-Codina; Gerrit Schwesig
Published in:
Small, Issue 8, 2020, ISSN 1613-6829
Publisher:
Wiley-VCH
DOI:
10.1002/smll.201906640
Author(s):
Philémon Roussel, Gaël Le Godais, Florent Bocquelet, Marie Palma, Jiang Hongjie, Shaomin Zhang, Anne-Lise Giraud, Pierre Mégevand, Kai Miller, Johannes Gehrig, Christian Kell, Philippe Kahane, Stéphan Chabardés, Blaise Yvert
Published in:
Journal of Neural Engineering, Issue 17/5, 2020, Page(s) 056028, ISSN 1741-2552
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1741-2552/abb25e
Author(s):
T. Proix, J. Delgado-Saa, A. Christien, S. Martin, B. Pasley, R.T. Knight, X. Tian, D. Poeppel, W.K. Doyle, O. Devinsky, L.H. Arnal, P. Mégevand, A.L. Giraud
Published in:
Nature Communications, Issue 10/01/2022, 2022, Page(s) 13, 48, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-021-27725-3
Author(s):
Anastasios G. Polyravas, Nathan Schaefer, Vincenzo F. Curto, Andrea Bonaccini Calia, Anton Guimera-Brunet, Jose A. Garrido, George G. Malliaras
Published in:
Applied Physics Letters, Issue 117/7, 2020, Page(s) 073302, ISSN 0003-6951
Publisher:
American Institute of Physics
DOI:
10.1063/5.0019693
Author(s):
Stephen Rainey
Published in:
Philosophy, Psychiatry, & Psychology, 2022, ISSN 1071-6076
Publisher:
Johns Hopkins University Press
DOI:
10.1353/ppp.2022.0005
Author(s):
Woodington BJ, Curto VF, Yu Y-L, Martínez-Domínguez H, Coles L, Malliaras GG, Proctor CM, Barone DG
Published in:
Science Advances, Issue 5 May 2021, 2021, ISSN 2375-2548
Publisher:
AAAS
DOI:
10.1126/sciadv.abg7833
Author(s):
Florian Fallegger; Giuseppe Schiavone; Elvira Pirondini; Fabien Wagner; Fabien Wagner; Nicolas Vachicouras; Ludovic Serex; Gregory Zegarek; Adrien May; Paul E. Constanthin; Marie Palma; Mehrdad Khoshnevis; Dirk Van Roost; Blaise Yvert; Grégoire Courtine; Grégoire Courtine; Karl Lothard Schaller; Jocelyne Bloch; Stéphanie P. Lacour
Published in:
Advanced Science, Issue 8 March 2021, 2021, Page(s) 2003761:1–9, ISSN 3397-7054
Publisher:
Wiley
DOI:
10.1002/advs.202003761
Author(s):
Gurke J, Naegele TE, Hilton S, Pezone R, Curto VF, Barone DG, List-Kratochvil EJW, Carnicer-Lombarte A, Malliaras GG
Published in:
Materials Horizons, Issue 2022-04-27, 2022, ISSN 2051-6347
Publisher:
RSC
DOI:
10.1039/d1mh01855h
Author(s):
R. Garcia-Cortadella, G. Schwesig, C. Jeschke, X. Illa, Anna L. Gray, S. Savage, E. Stamatidou, I. Schiessl, E. Masvidal-Codina, K. Kostarelos, A. Guimerà-Brunet, A. Sirota, J. A. Garrido
Published in:
Nature Communications, Issue 12/1, 2021, Page(s) 211, ISSN 2041-1723
Publisher:
Nature Publishing Group
DOI:
10.1038/s41467-020-20546-w
Author(s):
Stephen Rainey
Published in:
Philosophy, Psychiatry, & Psychology, 2022, ISSN 1071-6076
Publisher:
Johns Hopkins University Press
DOI:
10.1353/ppp.2022.0007
Author(s):
E. Fourneret
Published in:
La vulnérabilité au prisme du monde technologique : Enjeux éthiques, 2020, Page(s) Chapter 2, ISBN 2868207529
Publisher:
Presses Universitaires de Strasbourg
Author(s):
S. Rainey
Published in:
Future Morality, 2021, Page(s) Chapter 15, ISBN 9780198862086
Publisher:
Future Morality
Author(s):
Astobiza, A., Ausin, T., Ferrer., R., Rainey., S.
Published in:
The Age of Artificial Intelligence: An Exploration, 2020, ISBN 978-1-62273-872-4
Publisher:
Vernon Press
Author(s):
Stephen Rainey, Kevin McGillivray, Tyr Fothergill, Hannah Maslen, Bernd Stahl, Christoph Bublitz
Published in:
Clinical Neurotechnology Meets Artificial Intelligence: Philosophical, Ethical, Legal and Social Implications, 2021, Page(s) 141-154
Publisher:
Springer Nature Switzerland
DOI:
10.1007/978-3-030-64590-8
Author(s):
Stephen Rainey
Published in:
Clinical Neurotechnology meets Artificial Intelligence: Philosophical, Ethical, Legal and Social Implications, 2021, Page(s) 169-181
Publisher:
Springer Nature Switzerland
Author(s):
Christopher J. Bettinger, Melanie Ecker, Takashi Daniel Yoshida Kozai, George G. Malliaras, Ellis Meng, Walter Voit
Published in:
MRS Bulletin, Issue 45/8, 2020, Page(s) 655-668, ISSN 0883-7694
Publisher:
Materials Research Society
DOI:
10.1557/mrs.2020.195
Author(s):
Jose Cisneros-Fernandez, Anton Guimera-Brunet, Ramon Garcia-Cortadella, Nathan Schafer, Jose A. Garrido, Lluis Teres, Francisco Serra-Graells
Published in:
2020 27th IEEE International Conference on Electronics, Circuits and Systems (ICECS), Issue Proceedings of the IEEE ICECS 2020, 2020, Page(s) 1-4, ISBN 978-1-7281-6044-3
Publisher:
IEEE
DOI:
10.1109/icecs49266.2020.9294890
Author(s):
Jose Cisneros-Fernandez, Michele Dei, Lluis Teres, Francisco Serra-Graells
Published in:
2019 IEEE International Symposium on Circuits and Systems (ISCAS), 2019, Page(s) 1-5, ISBN 978-1-7281-0397-6
Publisher:
IEEE
DOI:
10.1109/iscas.2019.8702544
Author(s):
Delgado J, Christen A, Martin S, Pasley B, Knight R, Giraud A
Published in:
BioRxiv, 2018
Publisher:
Cold Spring Harbor Laboratory
DOI:
10.1101/481572
Author(s):
Nikolaos Karalis, Anton Sirota
Published in:
bioRxiv, 2018
Publisher:
Cold Spring Harbor Laboratory
DOI:
10.1101/392530
Intellectual Property Rights
Application/Publication number:
ES
1641.1420
Date:
2018-11-06
Applicant(s):
FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
Application/Publication number:
20
382819
Date:
2020-09-17
Application/Publication number:
18
382593
Date:
2018-08-03
Application/Publication number:
18
382593
Date:
2018-08-03
Applicant(s):
FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
Application/Publication number:
ES
1641.1420
Date:
2018-11-06
Application/Publication number:
20
382819
Date:
2020-09-17
Applicant(s):
FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA
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