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Glaucoma – Advanced, LAbel-free High resolution Automated OCT Diagnostics

Objective

The project GALAHAD targets the critical need for better glaucoma diagnostic systems. Glaucoma is an age-related major cause of blindness. The eye disease is characterized by an irreversible damage to the optic nerve head caused by increased intra-ocular pressure. The current screening and basic diagnostics for the disease involve intra-ocular pressure measurement, visual field tests and detection of structural damage to the optic nerve head and retinal nerve fibre layer. The present methods have high rates of false positive or false negative results since the in depth analysis of optical nerve head damage is not possible due to the poor resolution of available optical technologies. A leading candidate is optical coherence tomography (OCT), but the required axial resolution is ~1 μm, well beyond the 3-5 μm resolution of commercial systems. GALAHAD aims to develop a label free, compact and easy to operate high resolution diagnostic OCT system. The multiband and multimodal system will use submicron ultra-high resolution polarisation sensitive OCT (UHR PS OCT). The key breakthrough elements are: (i) A revolutionary low cost multiband supercontinuum light source. (ii.) Ground-breaking ultra-broadband photonic components required to exploit such a source. (iii.) Automated glaucoma screening algorithms: using end user evaluation of cell and animal models and tissue samples, automated algorithms will be developed, trained and tested so that non-expert operators will be able to perform glaucoma screening. The GALAHAD in depth glaucoma diagnostics after a positive screening with conventional methods will dramatically reduce false positive and false negative screening results and decrease the number of patients suffering from glaucoma-related disability. The project is driven by world leading companies and manufacturers of OCT systems and guided by requirement specifications and validated by high ranking clinical and experimental ophthalmologists in their clinical settings.

Call for proposal

H2020-ICT-2016-2017

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Sub call

H2020-ICT-2016-1

Coordinator

GOOCH & HOUSEGO (TORQUAY) LIMITED
Net EU contribution
€ 779 156,00
Address
Broomhill Way Unit A
TQ2 7QL Torquay Devon
United Kingdom

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Region
South West (England) Devon Torbay
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,25

Participants (9)

OPTOS PUBLIC LIMITED COMPANY
United Kingdom
Net EU contribution
€ 490 227,00
Address
Queensferry House Carnegie Campus
KY11 8GR Dunfermline Fife

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Region
Eastern Scotland Clackmannanshire and Fife
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,50
NKT PHOTONICS A/S
Denmark
Net EU contribution
€ 543 793,00
Address
Blokken 84
3460 Birkerod

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Region
Danmark Hovedstaden Nordsjælland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,75
IBSEN PHOTONICS AS
Denmark
Net EU contribution
€ 480 240,00
Address
Ryttermarken 15-21
3520 Farum

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Region
Danmark Hovedstaden Nordsjælland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
VIVID COMPONENTS LTD
United Kingdom
Net EU contribution
€ 214 487,00
Address
Sigma House Oak View Close
TQ27FF Torquay

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South West (England) Devon Torbay
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,50
DANMARKS TEKNISKE UNIVERSITET
Denmark
Net EU contribution
€ 317 002,00
Address
Anker Engelunds Vej 101
2800 Kongens Lyngby

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Region
Danmark Hovedstaden Københavns omegn
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,50
UNIVERSITAT POLITECNICA DE VALENCIA
Spain
Net EU contribution
€ 329 390,00
Address
Camino De Vera Sn Edificio 3a
46022 Valencia

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Region
Este Comunitat Valenciana Valencia/València
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
GLOUCESTERSHIRE HOSPITALS NHS FOUNDATION TRUST
United Kingdom
Net EU contribution
€ 129 580,00
Address
Trust Headquarters Alexandra House Cheltenham General Hospital Sandford Road
GL53 7AN Cheltenham

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Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Gloucestershire
Activity type
Research Organisations
Other funding
€ 0,00
WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER
Germany
Net EU contribution
€ 473 246,00
Address
Schlossplatz 2
48149 Muenster

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Region
Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,25
REGION HOVEDSTADEN
Denmark
Net EU contribution
€ 239 659,00
Address
Kongens Vaenge 2
3400 Hillerod

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Region
Danmark Hovedstaden Nordsjælland
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 1,00