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Early-life stressors and LifeCycle health

Deliverables

Report on the relationships of early-life exposures with trajectories of cardiovascular and metabolic risk factors from birth to adulthood

We will study the associations of individual earlylife stressors and the integrated earlylife exposome with cardiometabolic phenotypes at various ages across the life course and with trajectories of those phenotypes

Report on the associations of early-life stressors during preconception, pregnancy, infancy and early childhood with lung function developmental trajectories and the risk of asthma from childhood until young adulthood

We will use individual participant data from the EU Child Cohort Network to identify earlylife stressors individually and integrated in the earlylife exposome with lung function trajectories and symptoms diagnosis and medication related to asthma Main outcomes include lung function FEV1 FEV1FVC FEF2575 FEF75 bronchial hyperresponsiveness and symptoms and diseases respiratory infections wheezing asthma

Report on internalizing and externalizing behavior and other mental health trajectories from birth to childhood, and their associations with psychopathology outcomes

We will model longitudinal life course trajectories of mental function from early life to adulthood using data from the EU Child Cohort Network These trajectories will include both tracking and stability of internalizing and externalizing behavioural indicators measured with the Child Behaviour Check List CBCL throughout childhood and the relationships of these behavioural indicators with psychopathology indicators in adolescence and adulthood

Report on associations of early-life stressors with DNA methylation at birth

We will use an EWAS approach to study the associations of the main indicators of early-life stressors and the integrated early-life exposome, before and during pregnancy on DNA methylation at birth measured in cord blood. We will also explore the associations of the overall early-life exposome, developed in WP3, during pregnancy, on cord blood methylation at birth.

Report on review of interventions focused on lifestyle stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on lifestyle stressors of parents and young children. In line with WP3, these stressors will include parental smoking, alcohol consumption, illicit drug use, sleep, physical activity and parent and childhood nutritional intake and status.

Report on exposome models based on proof-of-principle studies

We will develop protocols for analysis of associations of a fully integrated earlylife stressor model the earlylife exposome with lifecycle health outcomes and test these in proofofprinciple studies As input we will use the main earlylife stressors WP1 WP3 Deliverable 31 34 Proofofprinciple datasets will be those of the EUFP7 funded HELIX project wwwprojecthelixeu including six cohorts across Europe n1200 plus the Generation R Study n7000 and DNBC n70000

Report on review of interventions focused on migration stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence on interventions on stressors related to migration. In line with WP3, the stressors will include indicators at individual, neighbourhood and macro-levels such as country of origin of the individual, its parents, or grandparents, generation after migration, measurements of integration.

Report on approaches to analyse multiple stressor data in the context of longitudinal modelling

In WP3 we will develop models to analyse associations of multiple stressors many of which are multidimensional with health outcomes This task will further develop these methods by assessing approaches to analyse multiple correlated stressor data in the context of longitudinal modelling

Report on the persistence of DNA methylation differences related to early-life stressors

To establish the role of DNA methylation differences on later life health outcomes in more detail and to better understand how these differences may exert effects, we will examine DNA methylation differences from birth to early adulthood in relation to early-life stressors.

Report on review of interventions focused on urban environment stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on urban environment stressors. In line with WP3, these stressors will include measurements of air pollution, noise, green space, connectivity and walkability.

Report on the effects of early-life stressors on mental health and psychopathology life course trajectories

We will use data from the EU Child Cohort Network to study the associations of earlylife stressors including socioeconomic migrant urban environment and lifestyle related indicators and the integrated earlylife exposome with mental development mental health and risk factors for psychiatric diseases at various ages across the life course

Report on early-life stressors that are related to both asthma throughout childhood and lung function and COPD in adulthood

We will explore whether individual earlylife stressors and the integrated earlylife exposome related to impaired respiratory health at younger age also affect lung function and risk of COPD in adulthood

Report on review of interventions focused on socio-economic stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on socio-economic inequalities In line with WP3, socio-economic related stressors will include parental education, occupation, type of employment contract, family income, family size, child care and house property and size.

Report on cardiovascular developmental trajectories during fetal life, infancy and early childhood, and the relationship with early-life exposures and cardiovascular risk factors in childhood

We will use data from the EU Child Cohort Network partners that collected data before or during pregnancy and have detailed fetal and infant growth and cardiovascular development data. We will study associations of early-life stressors and the early-life exposome with adiposity and cardio-metabolic developmental trajectories in fetal life, infancy and early childhood (fetal and placental blood flow, cardiac and vascular dimensions, adiposity), and subsequently associations of these trajectories with risk factors for childhood for cardio-metabolic disease.

Report on various life course models for the effects of early-life exposures on later cardio-metabolic risk factors and disease

In line with deliverable 41 and WP7 we will compare various potential life course models to best explain the relationships of earlylife stressors and potential mediators with trajectories of cardiometabolic risk factors and disease All EU Child Cohort Network cohorts will contribute to one or more of these trajectories

Report on the relationships of early-life stressors with transient and persistent common allergies, and the extent to which these mediate associations of early-life stressors with life course chronic obstructive respiratory health and disease trajectories

We will relate individual earlylife stressors and the integrated earlylife exposome with common allergies from birth to young adulthood We will also examine if we can identify subgroups based on allergic and nonallergic pathways

Report on approaches for longitudinal data/health trajectories in the context of life course analyses

We will provide a detailed description of analytical options to analyse repeated measurements data. We will cover theoretical biostatical aspects, the link between statistical modelling and the underlying biological frameworks and more practical applications dealing with issues of implementation and interpretation.

Report on patterns of core and integrated socio-economic, migration, urban environment and lifestyle related stressors across Europe

We will use all core and integrated data from WP3 deliverables 3.1 - 3.4 and apply factor analysis and model-based latent class analysis to uncover the nature of the underlying dependencies between stressors and to define stressor patterns. Participating partner cohorts are those that have collected key variables in each of the areas. Particular attention will be paid to comparing of stressor patterns between regions

Report on approaches for causal inference in the context of life course trajectory analyses

We will develop an analysis plan providing a detailed description of options in study design and statistical analyses to apply causal inference methods to life course research. This will integrate theoretical and applied aspects, focusing on implementation and interpretation.

External project website launched

Project website accessible for general public and specific public. The website will be multi-layered. The homepage will be accessible to everyone; it will be based mainly on visual communication (videoclips, data visualisations, etc.); and it will link to specific pages for various stakeholder or target groups, including researchers, health care providers, patient organizations, patients and policymakers.

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Publications

Associations of Hair Cortisol Concentrations With Cardiometabolic Risk Factors in Childhood

Author(s): Florianne O L Vehmeijer, Susana Santos, Yolanda B de Rijke, Erica L T van den Akker, Janine F Felix, Elisabeth F C van Rossum, Vincent W V Jaddoe
Published in: The Journal of Clinical Endocrinology & Metabolism, 106/9, 2021, Page(s) e3400-e3413, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgab379

Genome‐wide DNA methylation patterns associated with sleep and mental health in children: a population‐based study

Author(s): Maria Elisabeth Koopman‐Verhoeff, Rosa H. Mulder, Jared M. Saletin, Irwin Reiss, Gijsbertus T.J. Horst, Janine F. Felix, Mary A. Carskadon, Henning Tiemeier, Charlotte A.M. Cecil
Published in: Journal of Child Psychology and Psychiatry, 61/10, 2020, Page(s) 1061-1069, ISSN 0021-9630
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jcpp.13252

Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

Author(s): Edwina H. Yeung, Weihua Guan, Xuehuo Zeng, Lucas A. Salas, Sunni L. Mumford, Paula de Prado Bert, Evelien R. van Meel, Anni Malmberg, Jordi Sunyer, Liesbeth Duijts, Janine F. Felix, Darina Czamara, Esa Hämäläinen, Elisabeth B. Binder, Katri Räikkönen, Jari Lahti, Stephanie J. London, Robert M. Silver, Enrique F. Schisterman
Published in: Clinical Epigenetics, 12/1, 2020, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-020-00852-2

Prevention of noncommunicable diseases by interventions in the preconception period: A FIGO position paper for action by healthcare practitioners

Author(s): Chandni Maria Jacob, Sarah Louise Killeen, Fionnuala M. McAuliffe, Judith Stephenson, Moshe Hod, Ivonne Diaz Yamal, Jaideep Malhotra, Edgar Mocanu, H. David McIntyre, Anne B. Kihara, Ronald C. Ma, Hema Divakar, Anil Kapur, Rui Ferriani, Ernest Ng, Laurie Henry, Zephne Van Der Spuy, Zev Rosenwaks, Mark A. Hanson
Published in: International Journal of Gynecology & Obstetrics, 151/S1, 2020, Page(s) 6-15, ISSN 0020-7292
Publisher: Elsevier BV
DOI: 10.1002/ijgo.13331

Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study

Author(s): Giulietta S. Monasso, Leanne K. Küpers, Vincent W. V. Jaddoe, Sandra G. Heil, Janine F. Felix
Published in: Clinical Epigenetics, 13/1, 2021, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-021-01065-x

Large-scale association analyses identify host factors influencing human gut microbiome composition

Author(s): Alexander Kurilshikov, Carolina Medina-Gomez, Rodrigo Bacigalupe, Djawad Radjabzadeh, Jun Wang, Ayse Demirkan, Caroline I. Le Roy, Juan Antonio Raygoza Garay, Casey T. Finnicum, Xingrong Liu, Daria V. Zhernakova, Marc Jan Bonder, Tue H. Hansen, Fabian Frost, Malte C. Rühlemann, Williams Turpin, Jee-Young Moon, Han-Na Kim, Kreete Lüll, Elad Barkan, Shiraz A. Shah, Myriam Fornage, Joanna Szopinska
Published in: Nature Genetics, 53/2, 2021, Page(s) 156-165, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-020-00763-1

Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium

Author(s): Justiina Ronkainen, Anni Heiskala, Florianne O.L. Vehmeijer, Estelle Lowry, Doretta Caramaschi, Guadalupe Estrada Gutierrez, Jonathan A. Heiss, Nadine Hummel, Elina Keikkala, Tuomas Kvist, Allison Kupsco, Phillip E. Melton, Giancarlo Pesce, Munawar H. Soomro, Marta Vives-Usano, Nour Baiz, Elisabeth Binder, Darina Czamara, Mònica Guxens, Sanna Mustaniemi, Stephanie J. London, Sebastian Rauschert,
Published in: Epigenetics, 2021, Page(s) 1-13, ISSN 1559-2294
Publisher: Landes Bioscience
DOI: 10.1080/15592294.2020.1864171

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

Author(s): Alexander Neumann, Esther Walton, Silvia Alemany, Charlotte Cecil, Juan Ramon González, Dereje D. Jima, Jari Lahti, Samuli T. Tuominen, Edward D. Barker, Elisabeth Binder, Doretta Caramaschi, Ángel Carracedo, Darina Czamara, Jorunn Evandt, Janine F. Felix, Bernard F. Fuemmeler, Kristine B. Gutzkow, Cathrine Hoyo, Jordi Julvez, Eero Kajantie, Hannele Laivuori, Rachel Maguire, Léa Maitre, Susan K
Published in: Translational Psychiatry, 10/1, 2020, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-020-01058-z

Fibre Intake Is Associated with Cardiovascular Health in European Children

Author(s): Susana Larrosa, Veronica Luque, Veit Grote, Ricardo Closa-Monasterolo, Natalia Ferré, Berthold Koletzko, Elvira Verduci, Dariusz Gruszfeld, Annick Xhonneux, Joaquin Escribano
Published in: Nutrients, 13/1, 2021, Page(s) 12, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13010012

Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

Author(s): R.C. Huang, P.E. Melton, M.A. Burton, L.J. Beilin, R Clarke-Harris, E Cook, K.M. Godfrey, G.C. Burdge, T.A. Mori, D Anderson, S. Rauschert, J. M. Craig, M.S. Kobor, J.L. MacIsaac, A.M. Morin, W.H. Oddy, C.E. Pennell, J.D. Holbrook, K.A. Lillycrop
Published in: Epigenetics, 2021, Page(s) 1-18, ISSN 1559-2294
Publisher: Landes Bioscience
DOI: 10.1080/15592294.2021.1876297

Applying the exposome concept in birth cohort research: a review of statistical approaches

Author(s): Susana Santos, Léa Maitre, Charline Warembourg, Lydiane Agier, Lorenzo Richiardi, Xavier Basagaña, Martine Vrijheid
Published in: European Journal of Epidemiology, 35/3, 2020, Page(s) 193-204, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-020-00625-4

Associations of Plasma Fatty Acid Patterns during Pregnancy with Respiratory and Allergy Outcomes at School Age

Author(s): Sara M. Mensink-Bout, Trudy Voortman, Marsela Dervishaj, Irwin K. M. Reiss, Johan C. De Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Published in: Nutrients, 12/10, 2020, Page(s) 3057, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12103057

Measuring Child Socio-Economic Position in Birth Cohort Research: The Development of a Novel Standardized Household Income Indicator

Author(s): Costanza Pizzi, Matteo Richiardi, Marie-Aline Charles, Barbara Heude, Jean-Louis Lanoe, Sandrine Lioret, Sonia Brescianini, Virgilia Toccaceli, Martine Vrijheid, Franco Merletti, Daniela Zugna, Lorenzo Richiardi
Published in: International Journal of Environmental Research and Public Health, 17/5, 2020, Page(s) 1700, ISSN 1660-4601
Publisher: MDPI
DOI: 10.3390/ijerph17051700

Global e-Learning in Early Nutrition and Lifestyle for International Healthcare Professionals: Design and Evaluation of the Early Nutrition Specialist Programme (ENS)

Author(s): Brigitte Brands, Ngoc Nhan Tran, Erin Baudendistel-Happ, Marina Sanchez-Garcia, Martin R. Fischer, Berthold Koletzko
Published in: Nutrients, 13/3, 2021, Page(s) 775, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13030775

Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium

Author(s): Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James R. Hébert, Fionnuala M. McAuliffe, Cecily C.
Published in: BMC Medicine, 19/1, 2021, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-021-01908-7

Most associations of early‐life environmental exposures and genetic risk factors poorly differentiate between eczema phenotypes: the Generation R Study

Author(s): C. Hu, L. Duijts, N.S. Erler, N.J. Elbert, C. Piketty, V. Bourdès, S. Blanchet‐Réthoré, J.C. Jongste, S.G.M.A. Pasmans, J.F. Felix, T. Nijsten
Published in: British Journal of Dermatology, 181/6, 2019, Page(s) 1190-1197, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.17879

Neonatal DNA methylation and childhood low prosocial behavior: An epigenome‐wide association meta‐analysis

Author(s): Mannan Luo, Alan J. Meehan, Esther Walton, Stefan Röder, Gunda Herberth, Ana C. Zenclussen, Marta Cosín‐Tomás, Jordi Sunyer, Rosa H. Mulder, Andrea P. Cortes Hidalgo, Marian J. Bakermans‐Kranenburg, Janine F. Felix, Caroline Relton, Matthew Suderman, Irene Pappa, Rianne Kok, Henning Tiemeier, Marinus H. IJzendoorn, Edward D. Barker, Charlotte A. M. Cecil
Published in: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 186/4, 2021, Page(s) 228-241, ISSN 1552-4841
Publisher: Wiley-Liss Inc
DOI: 10.1002/ajmg.b.32862

DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural conception

Author(s): B Penova-Veselinovic, P E Melton, R C Huang, J L Yovich, P Burton, L A Wijs, R J Hart
Published in: Human Reproduction, 36/7, 2021, Page(s) 2035-2049, ISSN 0268-1161
Publisher: Oxford University Press
DOI: 10.1093/humrep/deab078

Building resilient societies after COVID-19: the case for investing in maternal, neonatal, and child health

Author(s): Chandni Maria Jacob, Despina D Briana, Gian Carlo Di Renzo, Neena Modi, Flavia Bustreo, Gabriella Conti, Ariadne Malamitsi-Puchner, Mark Hanson
Published in: The Lancet Public Health, 5/11, 2020, Page(s) e624-e627, ISSN 2468-2667
Publisher: Elsevier Ltd.
DOI: 10.1016/s2468-2667(20)30200-0

Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis

Author(s): Hugo G. Quezada-Pinedo, Florian Cassel, Liesbeth Duijts, Martina U. Muckenthaler, Max Gassmann, Vincent W. V. Jaddoe, Irwin K. M. Reiss, Marijn J. Vermeulen
Published in: Nutrients, 13/7, 2021, Page(s) 2221, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13072221

Health of women and children is central to covid-19 recovery

Author(s): Neena Modi, Mark Hanson
Published in: BMJ, 2021, Page(s) n899, ISSN 1756-1833
Publisher: BMJ
DOI: 10.1136/bmj.n899

Sleep duration and problem behaviour in 8-year-old children in the Childhood Obesity Project

Author(s): Kathrin Guerlich, Dariusz Gruszfeld, Justyna Czech-Kowalska, Natàlia Ferré, Ricardo Closa-Monasterolo, Françoise Martin, Pascale Poncelet, Elvira Verduci, Berthold Koletzko, Veit Grote
Published in: European Child & Adolescent Psychiatry, 2021, ISSN 1018-8827
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00787-021-01731-8

Effect of Maternal Prepregnancy/Early‐Pregnancy Body Mass Index and Pregnancy Smoking and Alcohol on Congenital Heart Diseases: A Parental Negative Control Study

Author(s): Kurt Taylor, Ahmed Elhakeem, Johanna Lucia Thorbjørnsrud Nader, Tiffany C. Yang, Elena Isaevska, Lorenzo Richiardi, Tanja Vrijkotte, Angela Pinot de Moira, Deirdre M. Murray, Daragh Finn, Dan Mason, John Wright, Sam Oddie, Nel Roeleveld, Jennifer R. Harris, Anne‐Marie Nybo Andersen, Massimo Caputo, Deborah A. Lawlor
Published in: Journal of the American Heart Association, 10/11, 2021, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.120.020051

Impact of Treatment with RUTF on Plasma Lipid Profiles of Severely Malnourished Pakistani Children

Author(s): Engy Shokry, Kamran Sadiq, Sajid Soofi, Atif Habib, Naveed Bhutto, Arjumand Rizvi, Imran Ahmad, Hans Demmelmair, Olaf Uhl, Zulfiqar Bhutta, Berthold Koletzko
Published in: Nutrients, 12/7, 2020, Page(s) 2163, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12072163

Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

Author(s): Oliver Robinson, Marc Chadeau Hyam, Ibrahim Karaman, Rui Climaco Pinto, Mika Ala-Korpela, Evangelos Handakas, Giovanni Fiorito, He Gao, Andy Heard, Marjo‐Riitta Jarvelin, Matthew Lewis, Raha Pazoki, Silvia Polidoro, Ioanna Tzoulaki, Matthias Wielscher, Paul Elliott, Paolo Vineis
Published in: Aging Cell, 19/6, 2020, ISSN 1474-9718
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/acel.13149

Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries

Author(s): Jordi Julvez, Mónica López-Vicente, Charline Warembourg, Lea Maitre, Claire Philippat, Kristine B. Gützkow, Monica Guxens, Jorunn Evandt, Sandra Andrusaityte, Miguel Burgaleta, Maribel Casas, Leda Chatzi, Montserrat de Castro, David Donaire-González, Regina Gražulevičienė, Carles Hernandez-Ferrer, Barbara Heude, Rosie Mceachan, Mark Mon-Williams, Mark Nieuwenhuijsen, Oliver Robinson, Amrit
Published in: Environmental Pollution, 284, 2021, Page(s) 117404, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2021.117404

New guidelines, position paper, and insights from the FIGO Pregnancy Obesity and Nutrition Initiative (PONI)

Author(s): Mark A. Hanson, Fionnuala M. McAuliffe, Sarah Louise Killeen, Chandni Maria Jacob, Moshe Hod
Published in: International Journal of Gynecology & Obstetrics, 151/S1, 2020, Page(s) 1-3, ISSN 0020-7292
Publisher: Elsevier BV
DOI: 10.1002/ijgo.13321

Urban environment during early-life and blood pressure in young children

Author(s): Charline Warembourg, Mark Nieuwenhuijsen, Ferran Ballester, Montserrat de Castro, Leda Chatzi, Ana Esplugues, Barbara Heude, Léa Maitre, Rosemary McEachan, Oliver Robinson, Rémy Slama, Jordi Sunyer, Jose Urquiza, John Wright, Xavier Basagaña, Martine Vrijheid
Published in: Environment International, 146, 2021, Page(s) 106174, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2020.106174

Parental migrant status and health inequalities at birth: The role of immigrant educational selectivity

Author(s): Sandra Florian, Mathieu Ichou, Lidia Panico
Published in: Social Science & Medicine, 278, 2021, Page(s) 113915, ISSN 0277-9536
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.socscimed.2021.113915

Cardio‐metabolic risk factors during childhood in relation to lung function and asthma

Author(s): Sara M. Mensink‐Bout, Susana Santos, Johan C. Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Published in: Pediatric Allergy and Immunology, 32/5, 2021, Page(s) 945-952, ISSN 0905-6157
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pai.13509

First trimester fetal proportion volumetric measurements using a Virtual Reality approach

Author(s): Clarissa J. Wiertsema, Jan S. Erkamp, Annemarie G. M. G. J. Mulders, Eric A. P. Steegers, Liesbeth Duijts, Anton H. J. Koning, Romy Gaillard, Vincent W. V. Jaddoe
Published in: Prenatal Diagnosis, 41/7, 2021, Page(s) 868-876, ISSN 0197-3851
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/pd.5947

Associations of eczema phenotypes with emotional and behavioural problems from birth until school age. The Generation R Study

Author(s): C. Hu, T. Nijsten, S.G.M.A. Pasmans, J.C. Jongste, P.W. Jansen, L. Duijts
Published in: British Journal of Dermatology, 183/2, 2020, Page(s) 311-320, ISSN 0007-0963
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjd.18705

Associations of maternal early-pregnancy blood glucose and insulin concentrations with DNA methylation in newborns

Author(s): Madelon L. Geurtsen, Vincent W. V. Jaddoe, Romy Gaillard, Janine F. Felix
Published in: Clinical Epigenetics, 12/1, 2020, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-020-00924-3

Development of a prediction model to target screening for high blood pressure in children

Author(s): Marleen Hamoen, Marieke Welten, Daan Nieboer, Guannan Bai, Martijn W. Heymans, Jos W.R. Twisk, Hein Raat, Yvonne Vergouwe, Alet H. Wijga, Marlou L.A. de Kroon
Published in: Preventive Medicine, 132, 2020, Page(s) 105997, ISSN 0091-7435
Publisher: Academic Press
DOI: 10.1016/j.ypmed.2020.105997

Higher carotid-radial pulse wave velocity is associated with non-melancholic depressive symptoms in men – findings from Helsinki Birth Cohort Study

Author(s): Mia D. Eriksson, Johan G. Eriksson, Hannu Kautiainen, Minna K. Salonen, Tuija M. Mikkola, Eero Kajantie, Niko Wasenius, Mikaela von Bonsdorff, Päivi Korhonen, Merja K. Laine
Published in: Annals of Medicine, 53/1, 2021, Page(s) 531-540, ISSN 0785-3890
Publisher: Taylor & Francis
DOI: 10.1080/07853890.2021.1904277

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

Author(s): Florianne O. L. Vehmeijer, Leanne K. Küpers, Gemma C. Sharp, Lucas A. Salas, Samantha Lent, Dereje D. Jima, Gwen Tindula, Sarah Reese, Cancan Qi, Olena Gruzieva, Christian Page, Faisal I. Rezwan, Philip E. Melton, Ellen Nohr, Geòrgia Escaramís, Peter Rzehak, Anni Heiskala, Tong Gong, Samuli T. Tuominen, Lu Gao, Jason P. Ross, Anne P. Starling, John W. Holloway, Paul Yousefi, Gunn Marit Aasvang,
Published in: Genome Medicine, 12/1, 2020, ISSN 1756-994X
Publisher: BioMed Central
DOI: 10.1186/s13073-020-00810-w

Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations

Author(s): Fernando Pires Hartwig, Kate Tilling, George Davey Smith, Deborah A Lawlor, Maria Carolina Borges
Published in: International Journal of Epidemiology, 2021, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyaa266

Association between nasal and nasopharyngeal bacterial colonization in early life and eczema phenotypes

Author(s): Chen Hu, Liesbeth Duijts, Evelien R. Meel, Kirsten I. M. Looman, Jessica C. Kiefte‐de Jong, Luba M. Pardo, DirkJan Hijnen, Suzanne G. M. A. Pasmans, Johan C. Jongste, Henriette A. Moll, Tamar Nijsten
Published in: Clinical & Experimental Allergy, 51/5, 2021, Page(s) 716-725, ISSN 0954-7894
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cea.13869

Associations Between Intake of Sugar‐Containing Beverages in Infancy With Liver Fat Accumulation at School Age

Author(s): Madelon L. Geurtsen, Susana Santos, Romy Gaillard, Janine F. Felix, Vincent W. V. Jaddoe
Published in: Hepatology, 73/2, 2021, Page(s) 560-570, ISSN 0270-9139
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hep.31611

Allergenic food introduction and risk of childhood atopic diseases

Author(s): Niels J. Elbert, Jessica C. Kiefte-de Jong, Trudy Voortman, Tamar E. C. Nijsten, Nicolette W. de Jong, Vincent W. V. Jaddoe, Johan C. de Jongste, Roy Gerth van Wijk, Liesbeth Duijts, Suzanne G. M. A. Pasmans
Published in: PLOS ONE, 12/11, 2017, Page(s) e0187999, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0187999

Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births

Author(s): Elise M. Philips, Susana Santos, Leonardo Trasande, Juan J. Aurrekoetxea, Henrique Barros, Andrea von Berg, Anna Bergström, Philippa K. Bird, Sonia Brescianini, Carol Ní Chaoimh, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Nathalie Costet, Rachel Criswell, Sarah Crozier, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Marleen M. H. J. van Gelder
Published in: PLOS Medicine, 17/8, 2020, Page(s) e1003182, ISSN 1549-1676
Publisher: PLOS
DOI: 10.1371/journal.pmed.1003182

Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study

Author(s): Saranya Palaniswamy, Dipender Gill, N Maneka De Silva, Estelle Lowry, Jari Jokelainen, Toni Karhu, Shivaprakash J Mutt, Abbas Dehghan, Eeva Sliz, Daniel I Chasman, Markku Timonen, Heimo Viinamäki, Sirkka Keinänen-Kiukaanniemi, Elina Hyppönen, Karl-Heinz Herzig, Sylvain Sebert, Marjo-Riitta Järvelin
Published in: The American Journal of Clinical Nutrition, 111/5, 2020, Page(s) 1036-1047, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqaa056

Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study

Author(s): Tuija M. Mikkola, Hannu Kautiainen, Mikaela B. von Bonsdorff, Minna K. Salonen, Niko Wasenius, Eero Kajantie, Johan G. Eriksson
Published in: Quality of Life Research, 29/8, 2020, Page(s) 2039-2050, ISSN 0962-9343
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s11136-020-02453-1

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Author(s): Suzanne Vogelezang, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo A. Lakka, Niels Grarup, Markus Scholz, Peter J. van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O. Fedko, Natalia Vilor-Tejedor, Diana L. Cousminer, Marie Standl, Carol A. Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bace
Published in: PLOS Genetics, 16/10, 2020, Page(s) e1008718, ISSN 1553-7404
Publisher: PLOS
DOI: 10.1371/journal.pgen.1008718

Increased Th22 cell numbers in a general pediatric population with filaggrin haploinsufficiency: The Generation R Study

Author(s): Kirsten I. M. Looman, Minke M. F. Mierlo, Menno C. Zelm, Chen Hu, Liesbeth Duijts, Johan C. Jongste, Tamar Nijsten, Luba M. Pardo, Jessica C. Kiefte‐de Jong, Henriëtte A. Moll, Suzanne G. M. A. Pasmans
Published in: Pediatric Allergy and Immunology, 32/6, 2021, Page(s) 1360-1368, ISSN 0905-6157
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pai.13502

Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts

Author(s): Rozenn Nedelec, Jouko Miettunen, Minna Männikkö, Marjo-Riitta Järvelin, Sylvain Sebert
Published in: International Journal of Obesity, 45/2, 2021, Page(s) 404-414, ISSN 0307-0565
Publisher: Nature Publishing Group
DOI: 10.1038/s41366-020-00695-0

Living environment and its relationship to depressive mood: A systematic review

Author(s): Nina Rautio, Svetlana Filatova, Heli Lehtiniemi, Jouko Miettunen
Published in: International Journal of Social Psychiatry, 64/1, 2018, Page(s) 92-103, ISSN 0020-7640
Publisher: SAGE Publications
DOI: 10.1177/0020764017744582

Socioeconomic inequalities in reproductive outcomes in the Italian NINFEA birth cohort and the Piedmont Birth Registry

Author(s): Pizzi, C; Popovic, M; Isaevska, E; Rusconi, F; Moirano, G; Merletti, F; Richiardi, L
Published in: Epidemiologia & Prevenzione, 18, 2020, ISSN 2385-1937
Publisher: Inferenze Scarl
DOI: 10.19191/ep20.5-6.s1.p136.083

Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies

Author(s): Robin N. Beaumont, Sarah J. Kotecha, Andrew R. Wood, Bridget A. Knight, Sylvain Sebert, Mark I. McCarthy, Andrew T. Hattersley, Marjo-Riitta Järvelin, Nicholas J. Timpson, Rachel M. Freathy, Sailesh Kotecha
Published in: PLOS Genetics, 16/12, 2020, Page(s) e1009191, ISSN 1553-7404
Publisher: Public Library of Science (PLOS)
DOI: 10.1371/journal.pgen.1009191

Associations of Fat and Lean Body Mass with Circulating Amino Acids in Older Men and Women

Author(s): Tuija M Mikkola, Minna K Salonen, Eero Kajantie, Hannu Kautiainen, Johan G Eriksson
Published in: The Journals of Gerontology: Series A, 75/5, 2019, Page(s) 885-891, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glz126

Does smoking during pregnancy mediate educational disparities in preterm delivery? Findings from three large birth cohorts

Author(s): Gry Poulsen, Anne‐Marie Nybo Andersen, Vincent W. V. Jaddoe, Per Magnus, Hein Raat, Camilla Stoltenberg, Merete Osler, Laust Hvas Mortensen
Published in: Paediatric and Perinatal Epidemiology, 33/2, 2019, Page(s) 164-171, ISSN 0269-5022
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ppe.12544

Maternal iron status during early pregnancy and school‐age, lung function, asthma, and allergy: The Generation R Study

Author(s): Hugo G. Quezada‐Pinedo, Sara M. Mensink‐Bout, Irwin K. Reiss, Vincent W. V. Jaddoe, Marijn J. Vermeulen, Liesbeth Duijts
Published in: Pediatric Pulmonology, 56/6, 2021, Page(s) 1771-1778, ISSN 8755-6863
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ppul.25324

Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

Author(s): S. Rauschert, K. Raubenheimer, P. E. Melton, R. C. Huang
Published in: Clinical Epigenetics, 12/1, 2020, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-020-00842-4

Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

Author(s): Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R. Hébert, Fionnuala M. McAuliffe, Cecily C. Kelleher, Catherine M. Phillips
Published in: PLOS Medicine, 18/1, 2021, Page(s) e1003491, ISSN 1549-1676
Publisher: PLOS
DOI: 10.1371/journal.pmed.1003491

Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts

Author(s): Ahmed Ehakeem, Celia L. Gregson, Jon H. Tobias, Deborah A. Lawlor
Published in: Annals of Human Biology, 47/4, 2020, Page(s) 391-399, ISSN 0301-4460
Publisher: Taylor & Francis
DOI: 10.1080/03014460.2019.1707284

Prenatal exposure to organophosphate pesticides and brain morphology and white matter microstructure in preadolescents

Author(s): Michiel A. van den Dries, Sander Lamballais, Hanan El Marroun, Anjoeka Pronk, Suzanne Spaan, Kelly K. Ferguson, Matthew P. Longnecker, Henning Tiemeier, Mònica Guxens
Published in: Environmental Research, 191, 2020, Page(s) 110047, ISSN 0013-9351
Publisher: Academic Press
DOI: 10.1016/j.envres.2020.110047

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

Author(s): Monica del C. Gomez-Alonso, Anja Kretschmer, Rory Wilson, Liliane Pfeiffer, Ville Karhunen, Ilkka Seppälä, Weihua Zhang, Kirstin Mittelstraß, Simone Wahl, Pamela R. Matias-Garcia, Holger Prokisch, Sacha Horn, Thomas Meitinger, Luis R. Serrano-Garcia, Sylvain Sebert, Olli Raitakari, Marie Loh, Wolfgang Rathmann, Martina Müller-Nurasyid, Christian Herder, Michael Roden, Mikko Hurme, Marjo-Riitta
Published in: Clinical Epigenetics, 13/1, 2021, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-020-00957-8

Phthalate and Bisphenol Exposure during Pregnancy and Offspring Nonverbal IQ

Author(s): Michiel A. van den Dries, Mònica Guxens, Suzanne Spaan, Kelly K. Ferguson, Elise Philips, Susana Santos, Vincent W.V. Jaddoe, Akhgar Ghassabian, Leonardo Trasande, Henning Tiemeier, Anjoeka Pronk
Published in: Environmental Health Perspectives, 128/7, 2020, Page(s) 077009, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp6047

Estimated whole-brain and lobe-specific radiofrequency electromagnetic fields doses and brain volumes in preadolescents

Author(s): Alba Cabré-Riera, Hanan El Marroun, Ryan Muetzel, Luuk van Wel, Ilaria Liorni, Arno Thielens, Laura Ellen Birks, Livia Pierotti, Anke Huss, Wout Joseph, Joe Wiart, Myles Capstick, Manon Hillegers, Roel Vermeulen, Elisabeth Cardis, Martine Vrijheid, Tonya White, Martin Röösli, Henning Tiemeier, Mònica Guxens
Published in: Environment International, 142, 2020, Page(s) 105808, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2020.105808

Understanding the cumulative risk of maternal prenatal biopsychosocial factors on birth weight: a DynaHEALTH study on two birth cohorts

Author(s): Priyanka Parmar, Estelle Lowry, Florianne Vehmeijer, Hanan El Marroun, Alex Lewin, Mimmi Tolvanen, Evangelia Tzala, Leena Ala-Mursula, Karl-Heinz Herzig, Jouko Miettunen, Inga Prokopenko, Nina Rautio, Vincent WV Jaddoe, Marjo-Riitta Järvelin, Janine Felix, Sylvain Sebert
Published in: Journal of Epidemiology and Community Health, 2020, Page(s) jech-2019-213154, ISSN 0143-005X
Publisher: British Medical Association
DOI: 10.1136/jech-2019-213154

The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents

Author(s): Vincent W. V. Jaddoe, Janine F. Felix, Anne-Marie Nybo Andersen, Marie-Aline Charles, Leda Chatzi, Eva Corpeleijn, Nina Donner, Ahmed Elhakeem, Johan G. Eriksson, Rachel Foong, Veit Grote, Sido Haakma, Mark Hanson, Jennifer R. Harris, Barbara Heude, Rae-Chi Huang, Hazel Inskip, Marjo-Riitta Järvelin, Berthold Koletzko, Deborah A. Lawlor, Maarten Lindeboom, Rosemary R. C. McEachan, Tuija M. Mikkol
Published in: European Journal of Epidemiology, 35/7, 2020, Page(s) 709-724, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-020-00662-z

The EU Child Cohort Network’s core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables

Author(s): Angela Pinot de Moira, Sido Haakma, Katrine Strandberg-Larsen, Esther van Enckevort, Marjolein Kooijman, Tim Cadman, Marloes Cardol, Eva Corpeleijn, Sarah Crozier, Liesbeth Duijts, Ahmed Elhakeem, Johan G. Eriksson, Janine F. Felix, Sílvia Fernández-Barrés, Rachel E. Foong, Anne Forhan, Veit Grote, Kathrin Guerlich, Barbara Heude, Rae-Chi Huang, Marjo-Riitta Järvelin, Anne Cathrine Jørgensen,
Published in: European Journal of Epidemiology, 36/5, 2021, Page(s) 565-580, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-021-00733-9

APOE ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns—Helsinki Birth Cohort Study

Author(s): Ville Rantalainen, Jari Lahti, Eero Kajantie, Pentti Tienari, Johan G. Eriksson, Katri Raikkonen
Published in: Neurobiology of Aging, 73, 2019, Page(s) 230.e5-230.e8, ISSN 0197-4580
Publisher: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2018.09.005

Association of Gestational Age at Birth With Brain Morphometry

Author(s): Hanan El Marroun, Runyu Zou, Michelle F. Leeuwenburg, Eric A. P. Steegers, Irwin K. M. Reiss, Ryan L. Muetzel, Steven A. Kushner, Henning Tiemeier
Published in: JAMA Pediatrics, 174/12, 2020, Page(s) 1149, ISSN 2168-6203
Publisher: American Medical Association
DOI: 10.1001/jamapediatrics.2020.2991

Body Fat Distribution, Overweight, and Cardiac Structures in School‐Age Children: A Population‐Based Cardiac Magnetic Resonance Imaging Study

Author(s): Liza Toemen, Susana Santos, Arno A. Roest, Gavro Jelic, Aad van der Lugt, Janine F. Felix, Willem A. Helbing, Romy Gaillard, Vincent W. V. Jaddoe
Published in: Journal of the American Heart Association, 9/13, 2020, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.119.014933

Genome-wide DNA methylation patterns associated with general psychopathology in children

Author(s): Jolien Rijlaarsdam, Edward D. Barker, Chiara Caserini, M. Elisabeth Koopman-Verhoeff, Rosa H. Mulder, Janine F. Felix, Charlotte A.M. Cecil
Published in: Journal of Psychiatric Research, 140, 2021, Page(s) 214-220, ISSN 0022-3956
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.jpsychires.2021.05.029

Early-life environmental exposure determinants of child behavior in Europe: A longitudinal, population-based study

Author(s): Léa Maitre, Jordi Julvez, Monica López-Vicente, Charline Warembourg, Ibon Tamayo-Uria, Claire Philippat, Kristine B. Gützkow, Monica Guxens, Sandra Andrusaityte, Xavier Basagaña, Maribel Casas, Montserrat de Castro, Leda Chatzi, Jorunn Evandt, Juan R. Gonzalez, Regina Gražulevičienė, Line Smastuen Haug, Barbara Heude, Carles Hernandez-Ferrer, Mariza Kampouri, Dan Manson, Sandra Marquez, Ros
Published in: Environment International, 153, 2021, Page(s) 106523, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106523

Association of the serum metabolomic profile by nuclear magnetic resonance spectroscopy with sperm parameters: a cross-sectional study of 325 men

Author(s): Karema Al Rashid, Amy Taylor, Mary Ann Lumsden, Neil Goulding, Deborah A. Lawlor, Scott M. Nelson
Published in: F&S Science, 1/2, 2020, Page(s) 142-160, ISSN 2666-335X
Publisher: Elsevier
DOI: 10.1016/j.xfss.2020.10.003

Dynamic prediction of childhood high blood pressure in a population-based birth cohort: a model development study

Author(s): Marleen Hamoen, Yvonne Vergouwe, Alet H Wijga, Martijn W Heymans, Vincent W V Jaddoe, Jos W R Twisk, Hein Raat, Marlou L A de Kroon
Published in: BMJ Open, 8/11, 2018, Page(s) e023912, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2018-023912

Frequent Bullying Involvement and Brain Morphology in Children

Author(s): Ryan L. Muetzel, Rosa H. Mulder, Sander Lamballais, Andrea P. Cortes Hidalgo, Pauline Jansen, Berna Güroğlu, Meike W. Vernooiji, Manon Hillegers, Tonya White, Hanan El Marroun, Henning Tiemeier
Published in: Frontiers in Psychiatry, 10, 2019, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2019.00696

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Author(s): Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers, Alvin T. Kho, Ritu Roy, Lu Gao, Isabella Annesi-Maesano, Pooja Jain, Michelle Plusquin, Manolis Kogevinas, Catherine Allard, Florianne O. Vehmeijer, Nabila Kazmi, Lucas A. Salas, Faisal I. Rezwan, Hongmei Zhang, Sylvain Sebert, Darina Czamara, Sheryl L. Rifas-Shiman, Phillip E. Melton, Debbie A. Lawlor, Göran Pershagen, Carr
Published in: Genome Medicine, 12/1, 2020, ISSN 1756-994X
Publisher: BioMed Central
DOI: 10.1186/s13073-020-0716-9

Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics

Author(s): Joshua A. Bell, Diana L. Santos Ferreira, Abigail Fraser, Ana Luiza G. Soares, Laura D. Howe, Deborah A. Lawlor, David Carslake, George Davey Smith, Linda M. O’Keeffe
Published in: BMC Medicine, 19/1, 2021, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-021-01929-2

A population-based resource for intergenerational metabolomics analyses in pregnant women and their children: the Generation R Study

Author(s): Ellis Voerman, Vincent W. V. Jaddoe, Olaf Uhl, Engy Shokry, Jeannie Horak, Janine F. Felix, Berthold Koletzko, Romy Gaillard
Published in: Metabolomics, 16/4, 2020, ISSN 1573-3882
Publisher: Springer Verlag
DOI: 10.1007/s11306-020-01667-1

Radiofrequency electromagnetic fields from mobile communication: Description of modeled dose in brain regions and the body in European children and adolescents

Author(s): Laura Ellen Birks, Luuk van Wel, Ilaria Liorni, Livia Pierotti, Mònica Guxens, Anke Huss, Milena Foerster, Myles Capstick, Marloes Eeftens, Hanan El Marroun, Marisa Estarlich, Mara Gallastegi, Llúcia González Safont, Wout Joseph, Loreto Santa-Marina, Arno Thielens, Maties Torrent, Tanja Vrijkotte, Joe Wiart, Martin Röösli, Elisabeth Cardis, Roel Vermeulen, Martine Vrijheid
Published in: Environmental Research, 193, 2021, Page(s) 110505, ISSN 0013-9351
Publisher: Academic Press
DOI: 10.1016/j.envres.2020.110505

Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

Author(s): Lise G. Bjerregaard, Niko Wasenius, Rozenn Nedelec, Line K. Gjærde, Lars Ängquist, Karl-Heinz Herzig, Gorm B. Jensen, Erik L. Mortensen, Merete Osler, Kim Overvad, Tea Skaaby, Anne Tjønneland, Thorkild I.A. Sørensen, Marjo-Riitta Järvelin, Johan G. Eriksson, Sylvain Sebert, Jennifer L. Baker
Published in: Diabetes Care, 43/5, 2020, Page(s) 1000-1007, ISSN 0149-5992
Publisher: American Diabetes Association
DOI: 10.2337/dc19-1726

Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register

Author(s): Alina Rodriguez, Yingbo Wang, Anohki Ali Khan, Rufus Cartwright, Mika Gissler, Marjo-Riitta Järvelin
Published in: PLOS Medicine, 16/2, 2019, Page(s) e1002746, ISSN 1549-1676
Publisher: PLOS
DOI: 10.1371/journal.pmed.1002746

Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking: Development and Validation in Samples Collected from Adolescents and Adults

Author(s): Sebastian Rauschert, Phillip E. Melton, Anni Heiskala, Ville Karhunen, Graham Burdge, Jeffrey M. Craig, Keith M. Godfrey, Karen Lillycrop, Trevor A. Mori, Lawrence J. Beilin, Wendy H. Oddy, Craig Pennell, Marjo-Riitta Järvelin, Sylvain Sebert, Rae-Chi Huang
Published in: Environmental Health Perspectives, 128/9, 2020, Page(s) 097003, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp6076

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

Author(s): Sara Sammallahti, Andrea P. Cortes Hidalgo, Samuli Tuominen, Anni Malmberg, Rosa H. Mulder, Kelly J. Brunst, Silvia Alemany, Nancy S. McBride, Paul Yousefi, Jonathan A. Heiss, Nia McRae, Christian M. Page, Jianping Jin, Giancarlo Pesce, Doretta Caramaschi, Sheryl L. Rifas-Shiman, Nastassja Koen, Charleen D. Adams, Maria C. Magnus, Nour Baïz, Andrew Ratanatharathorn, Darina Czamara, Siri E. Håber
Published in: Molecular Psychiatry, 2021, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-020-00976-0

Combining Longitudinal Data From Different Cohorts to Examine the Life-Course Trajectory

Author(s): Rachael A Hughes, Kate Tilling, Deborah A Lawlor
Published in: American Journal of Epidemiology, 2021, ISSN 0002-9262
Publisher: Oxford University Press
DOI: 10.1093/aje/kwab190

Parental psychological distress during pregnancy and the risk of childhood lower lung function and asthma: a population-based prospective cohort study

Author(s): Evelien R van Meel, Gautam Saharan, Vincent WV Jaddoe, Johan C de Jongste, Irwin KM Reiss, Henning Tiemeier, Hanan El Marroun, Liesbeth Duijts
Published in: Thorax, 75/12, 2020, Page(s) 1074-1081, ISSN 0040-6376
Publisher: BMJ Publishing Group
DOI: 10.1136/thoraxjnl-2019-214099

ERS International Congress 2020: highlights from the Paediatric Assembly

Author(s): Cristina Ardura-Garcia, Sara Cuevas-Ocaña, Nadine Freitag, Asterios Kampouras, John A. King, Panayiotis Kouis, Sara M. Mensink-Bout, Abigail L. Whitehouse, Emma Williams, Theodore Dassios, Liesbeth Duijts, Refika H Ersu, Erol A. Gaillard, Alex R. Horsley, Marijke Proesmans, Robbert Rottier, Dirk Schramm, Alexander Moeller, Marielle W. Pijnenburg
Published in: ERJ Open Research, 7/1, 2021, Page(s) 00893-2020, ISSN 2312-0541
Publisher: European Respiratory Society
DOI: 10.1183/23120541.00893-2020

Timing- and Dose-Specific Associations of Prenatal Smoke Exposure With Newborn DNA Methylation

Author(s): Giulietta S Monasso, Vincent W V Jaddoe, Johan C de Jongste, Liesbeth Duijts, Janine F Felix
Published in: Nicotine & Tobacco Research, 22/10, 2020, Page(s) 1917-1922, ISSN 1469-994X
Publisher: Oxford University Press
DOI: 10.1093/ntr/ntaa069

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

Author(s): Jenny van Dongen, Fiona A. Hagenbeek, Matthew Suderman, Peter J. Roetman, Karen Sugden, Andreas G. Chiocchetti, Khadeeja Ismail, Rosa H. Mulder, Jonathan D. Hafferty, Mark J. Adams, Rosie M. Walker, Stewart W. Morris, Jari Lahti, Leanne K. Küpers, Georgia Escaramis, Silvia Alemany, Marc Jan Bonder, Mandy Meijer, Hill F. Ip, Rick Jansen, Bart M. L. Baselmans, Priyanka Parmar, Estelle Lowry, Fabian
Published in: Molecular Psychiatry, 2021, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-020-00987-x

Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts

Author(s): Estelle Lowry, Nina Rautio, Niko Wasenius, Tom A. Bond, Jari Lahti, Ioanna Tzoulaki, Abbas Dehghan, Anni Heiskala, Leena Ala-Mursula, Jouko Miettunen, Johan Eriksson, Marjo-Riitta Järvelin, Sylvain Sebert
Published in: BMC Public Health, 20/1, 2020, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/s12889-020-08763-w

Eczema phenotypes and risk of allergic and respiratory conditions in school age children

Author(s): Chen Hu, Tamar Nijsten, Evelien R. van Meel, Nicole S. Erler, Christophe Piketty, Nicolette W. de Jong, Suzanne G. M. A. Pasmans, Johan C. de Jongste, Liesbeth Duijts
Published in: Clinical and Translational Allergy, 10/1, 2020, ISSN 2045-7022
Publisher: BMC
DOI: 10.1186/s13601-020-0310-7

Associations of Th2, Th17, Treg cells, and IgA + memory B cells with atopic disease in children: The Generation R Study

Author(s): Kirsten I. M. Looman, Evelien R. Meel, Christina Grosserichter‐Wagener, Floor J. M. Vissers, Janice H. Klingenberg, Nicolette W. Jong, Johan C. Jongste, Suzanne G. M. A. Pasmans, Liesbeth Duijts, Menno C. Zelm, Henriëtte A. Moll
Published in: Allergy, 75/1, 2020, Page(s) 178-187, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14010

The early-life exposome and epigenetic age acceleration in children

Author(s): Paula de Prado-Bert, Carlos Ruiz-Arenas, Marta Vives-Usano, Sandra Andrusaityte, Solène Cadiou, Ángel Carracedo, Maribel Casas, Leda Chatzi, Payam Dadvand, Juan R. González, Regina Grazuleviciene, Kristine B. Gutzkow, Line S. Haug, Carles Hernandez-Ferrer, Hector C. Keun, Johanna Lepeule, Léa Maitre, Rosie McEachan, Mark J. Nieuwenhuijsen, Dolors Pelegrí, Oliver Robinson, Rémy Slama, Marina
Published in: Environment International, 155, 2021, Page(s) 106683, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106683

Maternal hemoglobin associates with preterm delivery and small for gestational age in two Finnish birth cohorts

Author(s): Justiina Ronkainen, Estelle Lowry, Anni Heiskala, Iida Uusitalo, Peppi Koivunen, Eero Kajantie, Marja Vääräsmäki, Marjo-Riitta Järvelin, Sylvain Sebert
Published in: European Journal of Obstetrics & Gynecology and Reproductive Biology, 238, 2019, Page(s) 44-48, ISSN 0301-2115
Publisher: Elsevier BV
DOI: 10.1016/j.ejogrb.2019.04.045

Metabolomic Signatures in Pediatric Crohn’s Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study

Author(s): Jair Gonzalez Marques, Engy Shokry, Klara Frivolt, Katharina Julia Werkstetter, Annecarin Brückner, Tobias Schwerd, Sibylle Koletzko, Berthold Koletzko
Published in: SLAS TECHNOLOGY: Translating Life Sciences Innovation, 26/2, 2021, Page(s) 165-177, ISSN 2472-6303
Publisher: SAGE Choice
DOI: 10.1177/2472630320969147

Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age

Author(s): Giulietta S Monasso, Susana Santos, Madelon L Geurtsen, Sandra G Heil, Janine F Felix, Vincent W V Jaddoe
Published in: The Journal of Nutrition, 151/6, 2021, Page(s) 1628-1636, ISSN 0022-3166
Publisher: American Society for Nutritional Sciences
DOI: 10.1093/jn/nxab039

Availability, use of, and satisfaction with green space, and children's mental wellbeing at age 4 years in a multicultural, deprived, urban area: results from the Born in Bradford cohort study

Author(s): Rosemary R C McEachan, Tiffany C Yang, Hannah Roberts, Kate E Pickett, Diana Arseneau-Powell, Christopher J Gidlow, John Wright, Mark Nieuwenhuijsen
Published in: The Lancet Planetary Health, 2/6, 2018, Page(s) e244-e254, ISSN 2542-5196
Publisher: Elsevier
DOI: 10.1016/S2542-5196(18)30119-0

Increased correlation between methylation sites in epigenome-wide replication studies: impact on analysis and results

Author(s): Maja Popovic, Francesca Fasanelli, Valentina Fiano, Annibale Biggeri, Lorenzo Richiardi
Published in: Epigenomics, 9/12, 2017, Page(s) 1489-1502, ISSN 1750-1911
Publisher: Future Medicine Ltd.
DOI: 10.2217/epi-2017-0073

Effects decomposition in mediation analysis: a numerical example

Author(s): Zugna D, Richiardi L
Published in: Epidemiologia & Prevenzione, 42-2, 2018, Page(s) 127-133, ISSN 1120-9763
Publisher: Zadig srl
DOI: 10.19191/EP18.2.P127.041

Maternal psychological distress during pregnancy and childhood health outcomes: a narrative review

Author(s): F. O. L. Vehmeijer, M. Guxens, L. Duijts, H. El Marroun
Published in: Journal of Developmental Origins of Health and Disease, 10/3, 2019, Page(s) 274-285, ISSN 2040-1744
Publisher: Cambridge University Press
DOI: 10.1017/s2040174418000557

Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts

Author(s): Zuelma A. Contreras, Zhanghua Chen, Theano Roumeliotaki, Isabella Annesi-Maesano, Nour Baïz, Andrea von Berg, Anna Bergström, Sarah Crozier, Liesbeth Duijts, Sandra Ekström, Esben Eller, Maria P. Fantini, Henrik Fomsgaard Kjaer, Francesco Forastiere, Beatrix Gerhard, Davide Gori, Margreet W. Harskamp-van Ginkel, Joachim Heinrich, Carmen Iñiguez, Hazel Inskip, Thomas Keil, Manolis Kogevinas, S
Published in: European Respiratory Journal, 52/3, 2018, Page(s) 1800504, ISSN 0903-1936
Publisher: European Respiratory Society
DOI: 10.1183/13993003.00504-2018

Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn

Author(s): Emilie M. Herzog, Alex J. Eggink, Sten P. Willemsen, Roderick C. Slieker, Kim P.J. Wijnands, Janine F. Felix, Jun Chen, Andrew Stubbs, Peter J. van der Spek, Joyce B. van Meurs, Régine P.M. Steegers-Theunissen
Published in: Placenta, 58, 2017, Page(s) 122-132, ISSN 0143-4004
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.placenta.2017.08.070

Population DNA methylation studies in the Developmental Origins of Health and Disease (DOHaD) framework

Author(s): J. F. Felix, C. A. M. Cecil
Published in: Journal of Developmental Origins of Health and Disease, 2018, Page(s) 1-8, ISSN 2040-1744
Publisher: Cambridge University Press
DOI: 10.1017/S2040174418000442

The effect of early growth patterns and lung function on the development of childhood asthma: a population based study

Author(s): Maribel Casas, Herman T den Dekker, Claudia J Kruithof, Irwin K Reiss, Martine Vrijheid, Jordi Sunyer, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
Published in: Thorax, 2018, Page(s) thoraxjnl-2017-211216, ISSN 0040-6376
Publisher: BMJ Publishing Group
DOI: 10.1136/thoraxjnl-2017-211216

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Author(s): Janine F Felix, Bonnie R Joubert, Andrea A Baccarelli, Gemma C Sharp, Catarina Almqvist, Isabella Annesi-Maesano, Hasan Arshad, Nour Baïz, Marian J Bakermans-Kranenburg, Kelly M Bakulski, Elisabeth B Binder, Luigi Bouchard, Carrie V Breton, Bert Brunekreef, Kelly J Brunst, Esteban G Burchard, Mariona Bustamante, Leda Chatzi, Monica Cheng Munthe-Kaas, Eva Corpeleijn, Darina Czamara, Dana Dabelea,
Published in: International Journal of Epidemiology, 47/1, 2017, Page(s) 22-23u, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyx190

Premature birth and circadian preference in young adulthood: evidence from two birth cohorts

Author(s): Johan Björkqvist, Anu-Katriina Pesonen, Liisa Kuula, Hanna-Maria Matinolli, Aulikki Lano, Marika Sipola-Leppänen, Marjaana Tikanmäki, Dieter Wolke, Marjo-Riitta Järvelin, Johan G Eriksson, Sture Andersson, Marja Vääräsmäki, Kati Heinonen, Katri Räikkönen, Petteri Hovi, Eero Kajantie
Published in: Chronobiology International, 35/4, 2018, Page(s) 555-564, ISSN 0742-0528
Publisher: Marcel Dekker Inc.
DOI: 10.1080/07420528.2017.1420078

Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

Author(s): Rebecca C. Richmond, Nicholas J. Timpson, Janine F. Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W. Jaddoe, Debbie A. Lawlor
Published in: PLOS Medicine, 14/1, 2017, Page(s) e1002221, ISSN 1549-1277
Publisher: Public Library of Science
DOI: 10.1371/journal.pmed.1002221

The role of respiratory tract infections and the microbiome in the development of asthma: A narrative review

Author(s): Evelien R. van Meel, Vincent W. V. Jaddoe, Klaus Bønnelykke, Johan C. de Jongste, Liesbeth Duijts
Published in: Pediatric Pulmonology, 52/10, 2017, Page(s) 1363-1370, ISSN 8755-6863
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ppul.23795

Sources of confounding in life course epidemiology

Author(s): S. Santos, D. Zugna, C. Pizzi, L. Richiardi
Published in: Journal of Developmental Origins of Health and Disease, 2018, Page(s) 1-7, ISSN 2040-1744
Publisher: Cambridge University Press
DOI: 10.1017/S2040174418000582

Exposure to elemental composition of outdoor PM 2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts

Author(s): Małgorzata J. Lubczyńska, Jordi Sunyer, Henning Tiemeier, Daniela Porta, Monika Kasper-Sonnenberg, Vincent W.V. Jaddoe, Xavier Basagaña, Albert Dalmau-Bueno, Francesco Forastiere, Jürgen Wittsiepe, Barbara Hoffmann, Mark Nieuwenhuijsen, Gerard Hoek, Kees de Hoogh, Bert Brunekreef, Mònica Guxens
Published in: Environment International, 109, 2017, Page(s) 170-180, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2017.09.015

Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study

Author(s): Herman T. den Dekker, Vincent W. V. Jaddoe, Irwin K. Reiss, Johan C. de Jongste, Liesbeth Duijts
Published in: American Journal of Respiratory and Critical Care Medicine, 197/2, 2018, Page(s) 183-192, ISSN 1073-449X
Publisher: American Thoracic Society
DOI: 10.1164/rccm.201703-0631oc

Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study

Author(s): Maria C Magnus, Kozeta Miliku, Anna Bauer, Stephanie M Engel, Janine F Felix, Vincent W V Jaddoe, Debbie A Lawlor, Stephanie J London, Per Magnus, Ralph McGinnis, Wenche Nystad, Christian M Page, Fernando Rivadeneira, Lars C Stene, German Tapia, Nicholas Williams, Carolina Bonilla, Abigail Fraser
Published in: BMJ, 2018, Page(s) k2167, ISSN 0959-8138
Publisher: British Medical Association
DOI: 10.1136/bmj.k2167

Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

Author(s): Gemma C Sharp, Ryan Arathimos, Sarah E Reese, Christian M Page, Janine Felix, Leanne K Küpers, Sheryl L Rifas-Shiman, Chunyu Liu, Kimberley Burrows, Shanshan Zhao, Maria C Magnus, Liesbeth Duijts, Eva Corpeleijn, Dawn L DeMeo, Augusto Litonjua, Andrea Baccarelli, Marie-France Hivert, Emily Oken, Harold Snieder, Vincent Jaddoe, Wenche Nystad, Stephanie J London, Caroline L Relton, Luisa Zuccolo
Published in: Epigenomics, 10/1, 2018, Page(s) 27-42, ISSN 1750-1911
Publisher: Future Medicine Ltd.
DOI: 10.2217/epi-2017-0095

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Author(s): Robin N Beaumont, Nicole M Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C Richmond, Lavinia Paternoster, Jonathan P Bradfield, Eskil Kreiner-Møller, Ville Huikari, Sarah Metrustry, Kathryn L Lunetta, Jodie N Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J Barton, Ana Espinosa, Julie A Marsh, Catherine Potter, Ge Zhang
Published in: Human Molecular Genetics, 27/4, 2018, Page(s) 742-756, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx429

A population-based prospective cohort study examining the influence of early-life respiratory tract infections on school-age lung function and asthma

Author(s): Evelien R van Meel, Herman T den Dekker, Niels J Elbert, Pauline W Jansen, Henriëtte A Moll, Irwin K Reiss, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
Published in: Thorax, 73/2, 2018, Page(s) 167-173, ISSN 0040-6376
Publisher: BMJ Publishing Group
DOI: 10.1136/thoraxjnl-2017-210149

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Author(s): Johannes Waage, Marie Standl, John A. Curtin, Leon E. Jessen, Jonathan Thorsen, Chao Tian, Nathan Schoettler, Carlos Flores, Abdel Abdellaoui, Tarunveer S. Ahluwalia, Alexessander C. Alves, Andre F. S. Amaral, Josep M. Antó, Andreas Arnold, Amalia Barreto-Luis, Hansjörg Baurecht, Catharina E. M. van Beijsterveldt, Eugene R. Bleecker, Sílvia Bonàs-Guarch, Dorret I. Boomsma, Susanne Brix, Supind
Published in: Nature Genetics, 50/8, 2018, Page(s) 1072-1080, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-018-0157-1

Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children

Author(s): Mònica Guxens, Małgorzata J. Lubczyńska, Ryan L. Muetzel, Albert Dalmau-Bueno, Vincent W.V. Jaddoe, Gerard Hoek, Aad van der Lugt, Frank C. Verhulst, Tonya White, Bert Brunekreef, Henning Tiemeier, Hanan El Marroun
Published in: Biological Psychiatry, 84/4, 2018, Page(s) 295-303, ISSN 0006-3223
Publisher: Elsevier BV
DOI: 10.1016/j.biopsych.2018.01.016

Maternal and fetal genetic contribution to gestational weight gain

Author(s): N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe Jr, T Rou
Published in: International Journal of Obesity, 42/4, 2017, Page(s) 775-784, ISSN 0307-0565
Publisher: Nature Publishing Group
DOI: 10.1038/ijo.2017.248

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Author(s): Florence Demenais, Patricia Margaritte-Jeannin, Kathleen C. Barnes, William O. C. Cookson, Janine Altmüller, Wei Ang, R. Graham Barr, Terri H. Beaty, Allan B. Becker, John Beilby, Hans Bisgaard, Unnur Steina Bjornsdottir, Eugene Bleecker, Klaus Bønnelykke, Dorret I. Boomsma, Emmanuelle Bouzigon, Christopher E. Brightling, Myriam Brossard, Guy G. Brusselle, Esteban Burchard, Kristin M. Burkart, A
Published in: Nature Genetics, 50/1, 2018, Page(s) 42-53, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-017-0014-7

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

Author(s): Gemma C Sharp, Lucas A Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W Holloway, Akram Ghantous, Simon K Merid, Kelly M Bakulski, Leanne K Küpers, Hongmei Zhang, Rebecca C Richmond, Christian M Page, Liesbeth Duijts, Rolv T Lie, Phillip E Melton, J
Published in: Human Molecular Genetics, 26/20, 2017, Page(s) 4067-4085, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddx290

Baseline selection on a collider: a ubiquitous mechanism occurring in both representative and selected cohort studies

Author(s): Lorenzo Richiardi, Neil Pearce, Eva Pagano, Daniela Di Cuonzo, Daniela Zugna, Costanza Pizzi
Published in: Journal of Epidemiology and Community Health, 73/5, 2019, Page(s) 475-480, ISSN 0143-005X
Publisher: British Medical Association
DOI: 10.1136/jech-2018-211829

Narrative review of reviews of preconception interventions to prevent an increased risk of obesity and non‐communicable diseases in children

Author(s): Chandni Maria Jacob, Marie‐Louise Newell, Mark Hanson
Published in: Obesity Reviews, 20/S1, 2019, Page(s) 5-17, ISSN 1467-7881
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/obr.12769

Do the concepts of “life course approach” and “developmental origins of health and disease” underpin current maternity care? Study protocol

Author(s): Chandni Maria Jacob, Wendy T. Lawrence, Hazel M. Inskip, Fionnuala M. McAuliffe, Sarah Louise Killeen, Mark Hanson
Published in: International Journal of Gynecology & Obstetrics, 147/2, 2019, Page(s) 140-146, ISSN 0020-7292
Publisher: Elsevier BV
DOI: 10.1002/ijgo.12955

Research question and study validity

Author(s): Richiardi L
Published in: Epidemiologia e prevenzione, 43/4, 2019, Page(s) 217-219, ISSN 1120-9763
Publisher: Zadig srl
DOI: 10.19191/ep19.4.p217.073

Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva

Author(s): Maja Popovic, Valentina Fiano, Francesca Fasanelli, Morena Trevisan, Chiara Grasso, Manuela Bianca Assumma, Anna Gillio‐Tos, Silvia Polidoro, Laura De Marco, Franca Rusconi, Franco Merletti, Daniela Zugna, Lorenzo Richiardi
Published in: Pediatric Allergy and Immunology, 30/3, 2019, Page(s) 305-314, ISSN 0905-6157
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pai.13023

Infant breastfeeding and childhood general, visceral, liver, and pericardial fat measures assessed by magnetic resonance imaging

Author(s): Suzanne Vogelezang, Susana Santos, Eline M van der Beek, Marieke Abrahamse-Berkeveld, Liesbeth Duijts, Aad van der Lugt, Janine F Felix, Vincent W V Jaddoe
Published in: The American Journal of Clinical Nutrition, 108/4, 2018, Page(s) 722-729, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqy137

Exposure to Maternal Depressive Symptoms in Fetal Life or Childhood and Offspring Brain Development: A Population-Based Imaging Study

Author(s): Runyu Zou, Henning Tiemeier, Jan van der Ende, Frank C. Verhulst, Ryan L. Muetzel, Tonya White, Manon Hillegers, Hanan El Marroun
Published in: American Journal of Psychiatry, 176/9, 2019, Page(s) 702-710, ISSN 0002-953X
Publisher: American Psychiatric Publishing, Inc.
DOI: 10.1176/appi.ajp.2019.18080970

Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort

Author(s): Judith S. Brand, Jane West, Derek Tuffnell, Philippa K. Bird, John Wright, Kate Tilling, Debbie A. Lawlor
Published in: BMC Medicine, 16/1, 2018, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-018-1191-7

The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial

Author(s): Harriet L. Mills, Nashita Patel, Sara L. White, Dharmintra Pasupathy, Annette L. Briley, Diana L. Santos Ferreira, Paul T. Seed, Scott M. Nelson, Naveed Sattar, Kate Tilling, Lucilla Poston, Deborah A. Lawlor
Published in: BMC Medicine, 17/1, 2019, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-018-1248-7

Epigenome-wide association study of seizures in childhood and adolescence

Author(s): Doretta Caramaschi, Charlie Hatcher, Rosa H. Mulder, Janine F. Felix, Charlotte A. M. Cecil, Caroline L. Relton, Esther Walton
Published in: Clinical Epigenetics, 12/1, 2020, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-019-0793-z

Income inequality and social gradients in children’s height: a comparison of cohort studies from five high-income countries

Author(s): Philippa K Bird, Kate E Pickett, Hilary Graham, Tomas Faresjö, Vincent W V Jaddoe, Johnny Ludvigsson, Hein Raat, Louise Seguin, Anne I Wijtzes, Jennifer J McGrath
Published in: BMJ Paediatrics Open, 3/1, 2019, Page(s) e000568, ISSN 2399-9772
Publisher: BMJ publishing group
DOI: 10.1136/bmjpo-2019-000568

Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

Author(s): Susana Santos, Iris Eekhout, Ellis Voerman, Romy Gaillard, Henrique Barros, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Luigi Gagliardi, Vagelis Georgiu, Keith M. Godfrey, Davide Gori, Veit Grote, Wojciech Hanke, Irva Hertz-Picciotto, Barb
Published in: BMC Medicine, 16/1, 2018, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-018-1189-1

Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood

Author(s): Andres Cardenas, Sabrina Faleschini, Andrea Cortes Hidalgo, Sheryl L. Rifas-Shiman, Andrea A. Baccarelli, Dawn L. DeMeo, Augusto A. Litonjua, Alexander Neumann, Janine F. Felix, Vincent W. V. Jaddoe, Hanan El Marroun, Henning Tiemeier, Emily Oken, Marie-France Hivert, Heather H. Burris
Published in: Clinical Epigenetics, 11/1, 2019, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-019-0653-x

Observed infant-parent attachment and brain morphology in middle childhood– A population-based study

Author(s): Andrea P. Cortes Hidalgo, Ryan Muetzel, Maartje P.C.M. Luijk, Marian J. Bakermans-Kranenburg, Hanan El Marroun, Meike W. Vernooij, Marinus H. van IJzendoorn, Tonya White, Henning Tiemeier
Published in: Developmental Cognitive Neuroscience, 40, 2019, Page(s) 100724, ISSN 1878-9293
Publisher: Elsevier BV
DOI: 10.1016/j.dcn.2019.100724

DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

Author(s): Petri Wiklund, Ville Karhunen, Rebecca C. Richmond, Priyanka Parmar, Alina Rodriguez, Maneka De Silva, Matthias Wielscher, Faisal I. Rezwan, Tom G. Richardson, Juha Veijola, Karl-Heinz Herzig, John W. Holloway, Caroline L. Relton, Sylvain Sebert, Marjo-Riitta Järvelin
Published in: Clinical Epigenetics, 11/1, 2019, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-019-0683-4

Newborn and childhood differential DNA methylation and liver fat in school-age children

Author(s): Madelon L. Geurtsen, Vincent W. V. Jaddoe, Lucas A. Salas, Susana Santos, Janine F. Felix
Published in: Clinical Epigenetics, 12/1, 2020, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-019-0799-6

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Author(s): Priyanka Parmar, Estelle Lowry, Giovanni Cugliari, Matthew Suderman, Rory Wilson, Ville Karhunen, Toby Andrew, Petri Wiklund, Matthias Wielscher, Simonetta Guarrera, Alexander Teumer, Benjamin Lehne, Lili Milani, Niek de Klein, Pashupati P. Mishra, Phillip E. Melton, Pooja R. Mandaviya, Silva Kasela, Jana Nano, Weihua Zhang, Yan Zhang, Andre G. Uitterlinden, Annette Peters, Ben Schöttker, Christi
Published in: EBioMedicine, 38, 2018, Page(s) 206-216, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2018.10.066

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis

Author(s): Olena Gruzieva, Cheng-Jian Xu, Paul Yousefi, Caroline Relton, Simon Kebede Merid, Carrie V. Breton, Lu Gao, Heather E. Volk, Jason I. Feinberg, Christine Ladd-Acosta, Kelly Bakulski, Charles Auffray, Nathanaël Lemonnier, Michelle Plusquin, Akram Ghantous, Zdenko Herceg, Tim S. Nawrot, Costanza Pizzi, Lorenzo Richiardi, Franca Rusconi, Paolo Vineis, Manolis Kogevinas, Janine F. Felix, Liesbeth Dui
Published in: Environmental Health Perspectives, 127/5, 2019, Page(s) 057012, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp4522

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

Author(s): Sinjini Sikdar, Roby Joehanes, Bonnie R Joubert, Cheng-Jian Xu, Marta Vives-Usano, Faisal I Rezwan, Janine F Felix, James M Ward, Weihua Guan, Rebecca C Richmond, Jennifer A Brody, Leanne K Küpers, Nour Baïz, Siri E Håberg, Jennifer A Smith, Sarah E Reese, Stella Aslibekyan, Cathrine Hoyo, Radhika Dhingra, Christina A Markunas, Tao Xu, Lindsay M Reynolds, Allan C Just, Pooja R Mandaviya, Akram
Published in: Epigenomics, 11/13, 2019, Page(s) 1487-1500, ISSN 1750-1911
Publisher: Future Medicine Ltd.
DOI: 10.2217/epi-2019-0066

Exposure to Air Pollution during Pregnancy and Childhood, and White Matter Microstructure in Preadolescents

Author(s): Małgorzata J. Lubczyńska, Ryan L. Muetzel, Hanan El Marroun, Xavier Basagaña, Maciej Strak, William Denault, Vincent W.V. Jaddoe, Manon Hillegers, Meike W. Vernooij, Gerard Hoek, Tonya White, Bert Brunekreef, Henning Tiemeier, Mònica Guxens
Published in: Environmental Health Perspectives, 128/2, 2020, Page(s) 027005, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp4709

Epigenomics of being bullied: changes in DNA methylation following bullying exposure

Author(s): Rosa H. Mulder, Esther Walton, Alexander Neumann, Lotte C. Houtepen, Janine F. Felix, Marian J. Bakermans-Kranenburg, Matthew Suderman, Henning Tiemeier, Marinus H. van IJzendoorn, Caroline L. Relton, Charlotte A. M. Cecil
Published in: Epigenetics, 2020, Page(s) 1-15, ISSN 1559-2294
Publisher: Landes Bioscience
DOI: 10.1080/15592294.2020.1719303

Residential Proximity to Major Roadways at Birth, DNA Methylation at Birth and Midchildhood, and Childhood Cognitive Test Scores: Project Viva(Massachusetts, USA)

Author(s): Cheng Peng, Martijn den Dekker, Andres Cardenas, Sheryl L. Rifas-Shiman, Heike Gibson, Golareh Agha, Maria H. Harris, Brent A. Coull, Joel Schwartz, Augusto A. Litonjua, Dawn L. DeMeo, Marie-France Hivert, Matthew W. Gilman, Sharon K. Sagiv, Yvonne de Kluizenaar, Janine F. Felix, Vincent W. Jaddoe, Emily Oken, Liesbeth Duijts, Diane R. Gold, Andrea A. Baccarelli
Published in: Environmental Health Perspectives, 126/9, 2018, Page(s) 097006, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp2034

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

Author(s): Herman T. den Dekker, Kimberley Burrows, Janine F. Felix, Lucas A. Salas, Ivana Nedeljkovic, Jin Yao, Sheryl L. Rifas-Shiman, Carlos Ruiz-Arenas, N. Amin, Mariona Bustamante, Dawn L. DeMeo, A. John Henderson, Caitlin G. Howe, Marie-France Hivert, M. Arfan Ikram, Johan C. de Jongste, Lies Lahousse, Pooja R. Mandaviya, Joyce B. van Meurs, Mariona Pinart, Gemma C. Sharp, Lisette Stolk, André G. U
Published in: European Respiratory Journal, 53/4, 2019, Page(s) 1801795, ISSN 0903-1936
Publisher: European Respiratory Society
DOI: 10.1183/13993003.01795-2018

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

Author(s): Jonathan P Bradfield, Suzanne Vogelezang, Janine F Felix, Alessandra Chesi, Øyvind Helgeland, Momoko Horikoshi, Ville Karhunen, Estelle Lowry, Diana L Cousminer, Tarunveer S Ahluwalia, Elisabeth Thiering, Eileen Tai-Hui Boh, Mohammad H Zafarmand, Natalia Vilor-Tejedor, Carol A Wang, Raimo Joro, Zhanghua Chen, William J Gauderman, Niina Pitkänen, Esteban J Parra, Lindsay Fernandez-Rhodes, Akram A
Published in: Human Molecular Genetics, 28/19, 2019, Page(s) 3327-3338, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddz161

Epigenome-wide meta-analysis of DNA methylation and childhood asthma

Author(s): Sarah E. Reese, Cheng-Jian Xu, Herman T. den Dekker, Mi Kyeong Lee, Sinjini Sikdar, Carlos Ruiz-Arenas, Simon K. Merid, Faisal I. Rezwan, Christian M. Page, Vilhelmina Ullemar, Phillip E. Melton, Sam S. Oh, Ivana V. Yang, Kimberley Burrows, Cilla Söderhäll, Dereje D. Jima, Lu Gao, Ryan Arathimos, Leanne K. Küpers, Matthias Wielscher, Peter Rzehak, Jari Lahti, Catherine Laprise, Anne-Marie Mador
Published in: Journal of Allergy and Clinical Immunology, 143/6, 2019, Page(s) 2062-2074, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2018.11.043

Maternal body mass index, gestational weight gain, and childhood abdominal, pericardial, and liver fat assessed by magnetic resonance imaging

Author(s): Susana Santos, Claire Monnereau, Janine F. Felix, Liesbeth Duijts, Romy Gaillard, Vincent W. V. Jaddoe
Published in: International Journal of Obesity, 43/3, 2019, Page(s) 581-593, ISSN 0307-0565
Publisher: Nature Publishing Group
DOI: 10.1038/s41366-018-0186-y

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

Author(s): Liang-Dar Hwang, Deborah A Lawlor, Rachel M Freathy, David M Evans, Nicole M Warrington
Published in: International Journal of Epidemiology, 48/5, 2019, Page(s) 1457-1467, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyz160

Maternal prepregnancy body mass index and offspring white matter microstructure: results from three birth cohorts

Author(s): Juan Verdejo-Román, Lassi Björnholm, Ryan L. Muetzel, Francisco José Torres-Espínola, Johannes Lieslehto, Vincent Jaddoe, Daniel Campos, Juha Veijola, Tonya White, Andrés Catena, Juha Nikkinen, Vesa Kiviniemi, Marjo-Riitta Järvelin, Henning Tiemeier, Cristina Campoy, Sylvain Sebert, Hanan El Marroun
Published in: International Journal of Obesity, 43/10, 2019, Page(s) 1995-2006, ISSN 0307-0565
Publisher: Nature Publishing Group
DOI: 10.1038/s41366-018-0268-x

Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts

Author(s): Tom A Bond, Ville Karhunen, Matthias Wielscher, Juha Auvinen, Minna Männikkö, Sirkka Keinänen-Kiukaanniemi, Marc J Gunter, Janine F Felix, Inga Prokopenko, Jian Yang, Peter M Visscher, David M Evans, Sylvain Sebert, Alex Lewin, Paul F O’Reilly, Debbie A Lawlor, Marjo-Riitta Jarvelin
Published in: International Journal of Epidemiology, 2019, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyz095

A Cross‐Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children

Author(s): Markus Juonala, Susan Ellul, Debbie A. Lawlor, Diana L. Santos Ferreira, John B. Carlin, Michael Cheung, Terence Dwyer, Melissa Wake, Richard Saffery, David P. Burgner
Published in: Journal of the American Heart Association, 8/14, 2019, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.118.011852

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Author(s): Leanne K. Küpers, Claire Monnereau, Gemma C. Sharp, Paul Yousefi, Lucas A. Salas, Akram Ghantous, Christian M. Page, Sarah E. Reese, Allen J. Wilcox, Darina Czamara, Anne P. Starling, Alexei Novoloaca, Samantha Lent, Ritu Roy, Cathrine Hoyo, Carrie V. Breton, Catherine Allard, Allan C. Just, Kelly M. Bakulski, John W. Holloway, Todd M. Everson, Cheng-Jian Xu, Rae-Chi Huang, Diana A. van der Plaat
Published in: Nature Communications, 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09671-3

Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes

Author(s): Ellis Voerman, Susana Santos, Hazel Inskip, Pilar Amiano, Henrique Barros, Marie-Aline Charles, Leda Chatzi, George P. Chrousos, Eva Corpeleijn, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Davide Gori, Wojciech Hanke, Irva Hertz-Picciotto, Barbara Heude, Marie-France Hivert, Daniel Hryhorczuk, Carmen Iñiguez, Anne M. Karvone
Published in: JAMA, 321/17, 2019, Page(s) 1702, ISSN 0098-7484
Publisher: American Medical Association
DOI: 10.1001/jama.2019.3820

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Author(s): Simon Haworth, Chin Yang Shapland, Caroline Hayward, Bram P. Prins, Janine F. Felix, Carolina Medina-Gomez, Fernando Rivadeneira, Carol Wang, Tarunveer S. Ahluwalia, Martine Vrijheid, Mònica Guxens, Jordi Sunyer, Ioanna Tachmazidou, Klaudia Walter, Valentina Iotchkova, Andrew Jackson, Louise Cleal, Jennifer Huffmann, Josine L. Min, Lærke Sass, Paul R. H. J. Timmers, George Davey Smith, Simon E.
Published in: Nature Communications, 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-07863-x

Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis

Author(s): Bernadeta Patro Golab, Susana Santos, Ellis Voerman, Debbie A Lawlor, Vincent W V Jaddoe, Romy Gaillard, Bernadeta Patro Golab, Susana Santos, Ellis Voerman, Henrique Barros, Anna Bergström, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Graham Devereux, Merete Eggesbø, Sandra Ekström, Maria P Fantini, Sara Farchi, Francesc
Published in: The Lancet Child & Adolescent Health, 2/11, 2018, Page(s) 812-821, ISSN 2352-4642
Publisher: Elsevier
DOI: 10.1016/s2352-4642(18)30273-6

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Author(s): Alexander Teumer, Yong Li, Sahar Ghasemi, Bram P. Prins, Matthias Wuttke, Tobias Hermle, Ayush Giri, Karsten B. Sieber, Chengxiang Qiu, Holger Kirsten, Adrienne Tin, Audrey Y. Chu, Nisha Bansal, Mary F. Feitosa, Lihua Wang, Jin-Fang Chai, Massimiliano Cocca, Christian Fuchsberger, Mathias Gorski, Anselm Hoppmann, Katrin Horn, Man Li, Jonathan Marten, Damia Noce, Teresa Nutile, Sanaz Sedaghat, Gard
Published in: Nature Communications, 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-11576-0

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Author(s): Jun Liu, Elena Carnero-Montoro, Jenny van Dongen, Samantha Lent, Ivana Nedeljkovic, Symen Ligthart, Pei-Chien Tsai, Tiphaine C. Martin, Pooja R. Mandaviya, Rick Jansen, Marjolein J. Peters, Liesbeth Duijts, Vincent W. V. Jaddoe, Henning Tiemeier, Janine F. Felix, Gonneke Willemsen, Eco J. C. de Geus, Audrey Y. Chu, Daniel Levy, Shih-Jen Hwang, Jan Bressler, Rahul Gondalia, Elias L. Salfati, Christ
Published in: Nature Communications, 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-10487-4

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

Author(s): Ellis Voerman, Susana Santos, Bernadeta Patro Golab, Pilar Amiano, Ferran Ballester, Henrique Barros, Anna Bergström, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Graham Devereux, Merete Eggesbø, Sandra Ekström, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Keith M. Godfrey, Davide Gori, Veit Gro
Published in: PLOS Medicine, 16/2, 2019, Page(s) e1002744, ISSN 1549-1676
Publisher: Public Library of Science
DOI: 10.1371/journal.pmed.1002744

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Author(s): M. Wuttke; Y. Li; M. Li; K. B. Sieber; M. F. Feitosa; M. Gorski; A. Tin; L. Wang; A. Y. Chu; A. Hoppmann; H. Kirsten; A. Giri; J. F. Chai; G. Sveinbjornsson; B. O. Tayo; T. Nutile; C. Fuchsberger; J. Marten; M. Cocca; S. Ghasemi; Y. Xu; K. Horn; D. Noce; P. J. van der Most; S. Sedaghat; Z. Yu; M. Akiyama; S. Afaq; T. S. Ahluwalia; P. Almgren; N. Amin; J. Arnlov; S. J. L. Bakker; N. Bansal; D. Bapt
Published in: Nature Genetics, 2019, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-019-0407-x

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Author(s): Nicole M. Warrington, Robin N. Beaumont, Momoko Horikoshi, Felix R. Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R. Wood, Anubha Mahajan, Jessica Tyrrell, Neil R. Robertson, N. William Rayner, Zhen Qiao, Gunn-Helen Moen, Marc Vaudel, Carmen J. Marsit, Jia Chen, Michael Nodzenski, Theresia M. Schnurr, Mohammad H. Zafarmand, Jonathan P. Bradfi
Published in: Nature Genetics, 51/5, 2019, Page(s) 804-814, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-019-0403-1

Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and parental negative control studies

Author(s): Judith S. Brand, Romy Gaillard, Jane West, Rosemary R. C. McEachan, John Wright, Ellis Voerman, Janine F. Felix, Kate Tilling, Deborah A. Lawlor
Published in: PLOS Medicine, 16/11, 2019, Page(s) e1002972, ISSN 1549-1676
Publisher: Public Library of Science
DOI: 10.1371/journal.pmed.1002972

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

Author(s): Alexessander Couto Alves, N. Maneka G. De Silva, Ville Karhunen, Ulla Sovio, Shikta Das, H. Rob Taal, Nicole M. Warrington, Alexandra M. Lewin, Marika Kaakinen, Diana L. Cousminer, Elisabeth Thiering, Nicholas J. Timpson, Tom A. Bond, Estelle Lowry, Christopher D. Brown, Xavier Estivill, Virpi Lindi, Jonathan P. Bradfield, Frank Geller, Doug Speed, Lachlan J. M. Coin, Marie Loh, Sheila J. Barton,
Published in: Science Advances, 5/9, 2019, Page(s) eaaw3095, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aaw3095

Caesarean section, but not induction of labour, is associated with major changes in cord blood metabolome

Author(s): Linda Marchioro, Engy Shokry, Aisling A. Geraghty, Eileen C. O’Brien, Olaf Uhl, Berthold Koletzko, Fionnuala M. McAuliffe
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-53810-1

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

Author(s): Nabila Kazmi, Gemma C. Sharp, Sarah E. Reese, Florianne O. Vehmeijer, Jari Lahti, Christian M. Page, Weiming Zhang, Sheryl L. Rifas-Shiman, Faisal I. Rezwan, Andrew J. Simpkin, Kimberley Burrows, Tom G. Richardson, Diana L. Santos Ferreira, Abigail Fraser, Quaker E. Harmon, Shanshan Zhao, Vincent W.V. Jaddoe, Darina Czamara, Elisabeth B. Binder, Maria C. Magnus, Siri E. Håberg, Wenche Nystad, Ell
Published in: Hypertension, 74/2, 2019, Page(s) 375-383, ISSN 0194-911X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.119.12634

Impact of infant protein supply and other early life factors on plasma metabolome at 5.5 and 8 years of age: a randomized trial

Author(s): Franca Fabiana Kirchberg, Christian Hellmuth, Martina Totzauer, Olaf Uhl, Ricardo Closa-Monasterolo, Joaquin Escribano, Dariusz Gruszfeld, Kinga Gradowska, Elvira Verduci, Benedetta Mariani, Melissa Moretti, Déborah Rousseaux, Berthold Koletzko
Published in: International Journal of Obesity, 44/1, 2020, Page(s) 69-81, ISSN 0307-0565
Publisher: Nature Publishing Group
DOI: 10.1038/s41366-019-0398-9

Validated inference of smoking habits from blood with a finite DNA methylation marker set

Author(s): Silvana C. E. Maas, Athina Vidaki, Rory Wilson, Alexander Teumer, Fan Liu, Joyce B. J. van Meurs, André G. Uitterlinden, Dorret I. Boomsma, Eco J. C. de Geus, Gonneke Willemsen, Jenny van Dongen, Carla J. H. van der Kallen, P. Eline Slagboom, Marian Beekman, Diana van Heemst, Leonard H. van den Berg, Liesbeth Duijts, Vincent W. V. Jaddoe, Karl-Heinz Ladwig, Sonja Kunze, Annette Peters, M. Arfan I
Published in: European Journal of Epidemiology, 34/11, 2019, Page(s) 1055-1074, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-019-00555-w

Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors

Author(s): Kozeta Miliku, Janine F. Felix, Trudy Voortman, Henning Tiemeier, Darryl W. Eyles, Thomas H. Burne, John J. McGrath, Vincent W.V. Jaddoe
Published in: Maternal & Child Nutrition, 15/2, 2018, Page(s) e12672, ISSN 1740-8695
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mcn.12672

Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age

Author(s): Ahmed Elhakeem, Monika Frysz, Kate Tilling, Jon H. Tobias, Deborah A. Lawlor
Published in: JAMA Network Open, 2/8, 2019, Page(s) e198918, ISSN 2574-3805
Publisher: American Medical Association
DOI: 10.1001/jamanetworkopen.2019.8918

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits

Author(s): Tao Huang, Tiange Wang, Yan Zheng, Christina Ellervik, Xiang Li, Meng Gao, Zhe Fang, Jin-Fang Chai, Tarun veer S. Ahluwalia, Yujie Wang, Trudy Voortman, Raymond Noordam, Alexis Frazier-Wood, Markus Scholz, Emily Sonestedt, Masato Akiyama, Rajkumar Dorajoo, Ang Zhou, Tuomas O. Kilpeläinen, Marcus E. Kleber, Sarah R. Crozier, Keith M. Godfrey, Rozenn Lemaitre, Janine F. Felix, Yuan Shi, Preeti Gupt
Published in: JAMA Network Open, 2/9, 2019, Page(s) e1910915, ISSN 2574-3805
Publisher: American Medical Association
DOI: 10.1001/jamanetworkopen.2019.10915

Which modifiable prenatal factors mediate the relation between socio‐economic position and a child's weight and length at birth?

Author(s): Morgane Ballon, Jérémie Botton, Anne Forhan, Blandine Lauzon‐Guillain, Maria Melchior, Fabienne El Khoury, Aurélie Nakamura, Marie Aline Charles, Sandrine Lioret, Barbara Heude
Published in: Maternal & Child Nutrition, 15/4, 2019, ISSN 1740-8695
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/mcn.12878

Effect of a low glycaemic index diet during pregnancy on maternal and cord blood metabolomic profiles: results from the ROLO randomized controlled trial

Author(s): Linda Marchioro, Aisling A. Geraghty, Olaf Uhl, Engy Shokry, Eileen C. O’Brien, Berthold Koletzko, Fionnuala M. McAuliffe
Published in: Nutrition & Metabolism, 16/1, 2019, ISSN 1743-7075
Publisher: BioMed Central
DOI: 10.1186/s12986-019-0378-z

A prospective population-based study of gestational vitamin D status and brain morphology in preadolescents

Author(s): Runyu Zou, Hanan El Marroun, John J. McGrath, Ryan L. Muetzel, Manon Hillegers, Tonya White, Henning Tiemeier
Published in: NeuroImage, 209, 2020, Page(s) 116514, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2020.116514

Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children

Author(s): A. C. Viuff, G. C. Sharp, D. Rai, T. B. Henriksen, L. H. Pedersen, K. J. Kyng, N. H. Staunstrup, A. Cortes, A. Neumann, J. F. Felix, H. Tiemeier, V. W. V. Jaddoe, C. L. Relton
Published in: Translational Psychiatry, 8/1, 2018, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-018-0286-4

Deriving the Dietary Approaches to Stop Hypertension (DASH) Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium

Author(s): Adrien M. Aubert, Anne Forhan, Blandine de Lauzon-Guillain, Ling-Wei Chen, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Sara M. Mensink-Bout, Liesbeth Duijts, Matthew Suderman, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Fionnuala M. McAuliffe, Cecily C. Kelleher, Catherine M. Phillips, Barbara Heude, Jonathan Y. Bernard
Published in: Nutrients, 11/11, 2019, Page(s) 2706, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11112706

Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health: The Early Nutrition Project Recommendations

Author(s): Berthold Koletzko, K.M. Godfrey, Lucilla Poston, Hania Szajewska, Johannes B. van Goudoever, Marita de Waard, Brigitte Brands, Rosalie M. Grivell, Andrea R. Deussen, Jodie M. Dodd, Bernadeta Patro-Golab, Bartlomiej M. Zalewski
Published in: Annals of Nutrition and Metabolism, 74/2, 2019, Page(s) 93-106, ISSN 0250-6807
Publisher: S. Karger AG
DOI: 10.1159/000496471

Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

Author(s): Jacob P. Thyssen, Tarunveer S. Ahluwalia, Lavinia Paternoster, Natalia Ballardini, Anna Bergström, Erik Melén, Bo L. Chawes, Jakob Stokholm, Jonathan O'B Hourihane, Donnchadh M. O'Sullivan, Peter Bager, Mads Melbye, Mariona Bustamante, Maties Torrent, Ana Esplugues, Liesbeth Duijts, Chen Hu, Niels J. Elbert, Suzanne G. M. A. Pasmans, Tamar E. C. Nijsten, Andrea Berg, Marie Standl, Tamara Schikow
Published in: Allergy, 2020, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.14162

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American, and Australian cohorts

Author(s): S Santos, E Voerman, P Amiano, H Barros, LJ Beilin, A Bergström, M‐A Charles, L Chatzi, C Chevrier, GP Chrousos, E Corpeleijn, O Costa, N Costet, S Crozier, G Devereux, M Doyon, M Eggesbø, MP Fantini, S Farchi, F Forastiere, V Georgiu, KM Godfrey, D Gori, V Grote, W Hanke, I Hertz‐Picciotto, B Heude, M‐F Hivert, D Hryhorczuk, R‐C Huang, H Inskip, AM Karvonen, LC Kenny, B Koletzko, LK Kü
Published in: BJOG: An International Journal of Obstetrics & Gynaecology, 2019, ISSN 1470-0328
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1471-0528.15661

Causal Inference in Environmental Epidemiology

Author(s): Neil Pearce, Jan P. Vandenbroucke, Deborah A. Lawlor
Published in: Epidemiology, 30/3, 2019, Page(s) 311-316, ISSN 1044-3983
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/ede.0000000000000987

Commercial complementary food use amongst European infants and children: results from the EU Childhood Obesity Project

Author(s): Melissa A. Theurich, Marta Zaragoza-Jordana, Veronica Luque, Dariusz Gruszfeld, Kinga Gradowska, Annick Xhonneux, Enrica Riva, Elvira Verduci, Pascale Poncelet, Louiza Damianidi, Berthold Koletzko, Veit Grote
Published in: European Journal of Nutrition, 2019, ISSN 1436-6207
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-019-02023-3

Are All Breast-fed Infants Equal? Clustering Metabolomics Data to Identify Predictive Risk Clusters for Childhood Obesity

Author(s): Franca Fabiana Kirchberg, Veit Grote, Dariusz Gruszfeld, Piotr Socha, Ricardo Closa-Monasterolo, Joaquin Escribano, Elvira Verduci, Benedetta Mariani, Jean-Paul Langhendries, Pascale Poncelet, Berthold Koletzko, Christian Hellmuth
Published in: Journal of Pediatric Gastroenterology and Nutrition, 68/3, 2019, Page(s) 408-415, ISSN 0277-2116
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mpg.0000000000002184

Maternal Early‐Pregnancy Glucose Concentrations and Liver Fat Among School‐Age Children

Author(s): Madelon L. Geurtsen, Rama J. Wahab, Janine F. Felix, Romy Gaillard, Vincent W.V. Jaddoe
Published in: Hepatology, 2021, ISSN 0270-9139
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hep.31910

Impaired glucose regulation, depressive symptoms, and health-related quality of life

Author(s): Jannica S Selenius, Niko S Wasenius, Hannu Kautiainen, Minna Salonen, Mikaela von Bonsdorff, Johan G Eriksson
Published in: BMJ Open Diabetes Research & Care, 8/1, 2020, Page(s) e001568, ISSN 2052-4897
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjdrc-2020-001568

The influence of Epstein‐Barr virus and cytomegalovirus on childhood respiratory health: A population‐based prospective cohort study

Author(s): Evelien R. Meel, Vincent W. V. Jaddoe, Irwin K. M. Reiss, Menno C. Zelm, Johan C. Jongste, Henriëtte A. Moll, Liesbeth Duijts
Published in: Clinical & Experimental Allergy, 50/4, 2020, Page(s) 499-507, ISSN 0954-7894
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cea.13579

Epigenome-wide associations between observed maternal sensitivity and offspring DNA methylation: a population-based prospective study in children

Author(s): Lorenza Dall’ Aglio, Jolien Rijlaarsdam, Rosa H. Mulder, Alexander Neumann, Janine F. Felix, Rianne Kok, Marian J. Bakermans-Kranenburg, Marinus H. van Ijzendoorn, Henning Tiemeier, Charlotte A.M. Cecil
Published in: Psychological Medicine, 2020, Page(s) 1-11, ISSN 0033-2917
Publisher: Cambridge University Press
DOI: 10.1017/s0033291720004353

Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review

Author(s): Romy Gaillard, John Wright, Vincent W.V. Jaddoe
Published in: Journal of Developmental Origins of Health and Disease, 10/3, 2019, Page(s) 314-321, ISSN 2040-1744
Publisher: Cambridge University Press
DOI: 10.1017/s2040174418000855

Maternal blood pressure and hypertensive disorders during pregnancy and childhood respiratory morbidity: the Generation R Study

Author(s): Freke A. Wilmink, Herman T. den Dekker, Johan C. de Jongste, Irwin K.M. Reiss, Vincent W.V. Jaddoe, Eric A. Steegers, Liesbeth Duijts
Published in: European Respiratory Journal, 52/5, 2018, Page(s) 1800378, ISSN 0903-1936
Publisher: European Respiratory Society
DOI: 10.1183/13993003.00378-2018

Dietary Quality and Dietary Inflammatory Potential During Pregnancy and Offspring Emotional and Behavioral Symptoms in Childhood: An Individual Participant Data Meta-analysis of Four European Cohorts

Author(s): Kinga Polanska, Pawel Kaluzny, Adrien M. Aubert, Jonathan Y. Bernard, Liesbeth Duijts, Hanan El Marroun, Wojciech Hanke, James R. Hébert, Barbara Heude, Agnieszka Jankowska, Giulia Mancano, Sara M. Mensink-Bout, Caroline Relton, Nitin Shivappa, Matthew Suderman, Elzbieta Trafalska, Ewelina Wesolowska, Raquel Garcia-Esteban, Mònica Guxens, Maribel Casas, Catherine M. Phillips
Published in: Biological Psychiatry, 89/6, 2021, Page(s) 550-559, ISSN 0006-3223
Publisher: Elsevier BV
DOI: 10.1016/j.biopsych.2020.10.008

Associations of Hair Cortisol Concentrations with General and Organ Fat Measures in Childhood

Author(s): Florianne O L Vehmeijer, Susana Santos, Romy Gaillard, Yolanda B de Rijke, Trudy Voortman, Erica L T van den Akker, Janine F Felix, Elisabeth F C van Rossum, Vincent W V Jaddoe
Published in: The Journal of Clinical Endocrinology & Metabolism, 106/2, 2020, Page(s) e551-e561, ISSN 0021-972X
Publisher: The Endocrine Society
DOI: 10.1210/clinem/dgaa785

Cognitive mediation in people with dementia: Development, structural, and construct validity of the first dementia‐specific measure

Author(s): Joshua Stott, Tim Cadman, Katrina Scior, Janina Brede, Eleanor Chadwick, Georgina Charlesworth
Published in: International Journal of Geriatric Psychiatry, 34/11, 2019, Page(s) 1590-1598, ISSN 0885-6230
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/gps.5169

Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

Author(s): Silvia Alemany, Philip R. Jansen, Ryan L. Muetzel, Natália Marques, Hanan El Marroun, Vincent W.V. Jaddoe, Tinca J.C. Polderman, Henning Tiemeier, Danielle Posthuma, Tonya White
Published in: Journal of the American Academy of Child & Adolescent Psychiatry, 58/6, 2019, Page(s) 600-607, ISSN 0890-8567
Publisher: Elsevier BV
DOI: 10.1016/j.jaac.2018.09.443

Birthweight DNA methylation signatures in infant saliva

Author(s): Chiara Moccia, Maja Popovic, Elena Isaevska, Valentina Fiano, Morena Trevisan, Franca Rusconi, Silvia Polidoro, Lorenzo Richiardi
Published in: Clinical Epigenetics, 13/1, 2021, ISSN 1868-7075
Publisher: Springer Verlag
DOI: 10.1186/s13148-021-01053-1

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Author(s): Christel M. Middeldorp, Janine F. Felix, Anubha Mahajan, Mark I. McCarthy
Published in: European Journal of Epidemiology, 34/3, 2019, Page(s) 279-300, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-019-00502-9

Nutritional Adequacy of Commercial Complementary Cereals in Germany

Author(s): Melissa A. Theurich, Berthold Koletzko, Veit Grote
Published in: Nutrients, 12/6, 2020, Page(s) 1590, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12061590

Physical heaviness of work and sitting at work as predictors of mortality: a 26-year follow-up of the Helsinki Birth Cohort Study

Author(s): Tuija M Mikkola, Mikaela B von Bonsdorff, Minna K Salonen, Hannu Kautiainen, Leena Ala-Mursula, Svetlana Solovieva, Eira Viikari-Juntura, Johan G Eriksson
Published in: BMJ Open, 9/5, 2019, Page(s) e026280, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2018-026280

A population-based study on associations of stool microbiota with atopic diseases in school-age children

Author(s): Chen Hu, Evelien R. van Meel, Carolina Medina-Gomez, Robert Kraaij, Monica Barroso, Jessica Kiefte-de Jong, Djawad Radjabzadeh, Suzanne G.M.A. Pasmans, Nicolette W. de Jong, Johan C. de Jongste, Henriette A. Moll, Tamar Nijsten, Fernando Rivadeneira, Luba M. Pardo, Liesbeth Duijts
Published in: Journal of Allergy and Clinical Immunology, 148/2, 2021, Page(s) 612-620, ISSN 0091-6749
Publisher: Mosby Inc.
DOI: 10.1016/j.jaci.2021.04.001

A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years

Author(s): Chandni Maria Jacob, Polly Louise Hardy-Johnson, Hazel M. Inskip, Taylor Morris, Camille M. Parsons, Millie Barrett, Mark Hanson, Kathryn Woods-Townsend, Janis Baird
Published in: International Journal of Behavioral Nutrition and Physical Activity, 18/1, 2021, ISSN 1479-5868
Publisher: BioMed Central
DOI: 10.1186/s12966-020-01065-9

Maternal polyunsaturated fatty acids during pregnancy and offspring brain development in childhood

Author(s): Runyu Zou, Hanan El Marroun, Trudy Voortman, Manon Hillegers, Tonya White, Henning Tiemeier
Published in: The American Journal of Clinical Nutrition, 114/1, 2021, Page(s) 124-133, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1093/ajcn/nqab049

Prenatal exposure to non‐steroidal anti‐inflammatory drugs (NSAIDs) and neurodevelopmental outcomes in children

Author(s): Maja Markovic, Sonja A. Swanson, Bruno H. Stricker, Vincent W.V. Jaddoe, Frank C. Verhulst, Henning Tiemeier, Hanan El Marroun
Published in: Pharmacoepidemiology and Drug Safety, 28/4, 2019, Page(s) 452-459, ISSN 1053-8569
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/pds.4625

Air pollution exposure during pregnancy and childhood and brain morphology in preadolescents

Author(s): Małgorzata J. Lubczyńska, Ryan L. Muetzel, Hanan El Marroun, Gerard Hoek, Ingeborg M. Kooter, Errol M. Thomson, Manon Hillegers, Meike W. Vernooij, Tonya White, Henning Tiemeier, Mònica Guxens
Published in: Environmental Research, 198, 2021, Page(s) 110446, ISSN 0013-9351
Publisher: Academic Press
DOI: 10.1016/j.envres.2020.110446

Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence

Author(s): Rosa H Mulder, Alexander Neumann, Charlotte A M Cecil, Esther Walton, Lotte C Houtepen, Andrew J Simpkin, Jolien Rijlaarsdam, Bastiaan T Heijmans, Tom R Gaunt, Janine F Felix, Vincent W V Jaddoe, Marian J Bakermans-Kranenburg, Henning Tiemeier, Caroline L Relton, Marinus H van IJzendoorn, Matthew Suderman
Published in: Human Molecular Genetics, 30/1, 2021, Page(s) 119-134, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddaa280

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

Author(s): Yan Zheng, Tao Huang, Tiange Wang, Zhendong Mei, Zhonghan Sun, Tao Zhang, Christina Ellervik, Jin-Fang Chai, Xueling Sim, Rob M. van Dam, E-Shyong Tai, Woon-Puay Koh, Rajkumar Dorajoo, Seang-Mei Saw, Charumathi Sabanayagam, Tien Yin Wong, Preeti Gupta, Peter Rossing, Tarunveer S. Ahluwalia, Rebecca K. Vinding, Hans Bisgaard, Klaus Bønnelykke, Yujie Wang, Mariaelisa Graff, Trudy Voortman, Frank J.
Published in: European Journal of Epidemiology, 35/7, 2020, Page(s) 685-697, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-020-00638-z

Determination of saliva epigenetic age in infancy, and its association with parental socio-economic characteristics and pregnancy outcomes

Author(s): Maja Popovic, Valentina Fiano, Elena Isaevska, Chiara Moccia, Morena Trevisan, Franca Rusconi, Laura De Marco, Silvia Polidoro, Franco Merletti, Costanza Pizzi, Lorenzo Richiardi
Published in: Journal of Developmental Origins of Health and Disease, 12/2, 2021, Page(s) 319-327, ISSN 2040-1744
Publisher: Cambridge University Press
DOI: 10.1017/s2040174420000380

Implications of the Developmental Origins of Health and Disease concept for policy-making

Author(s): Chandni Maria Jacob, Mark Hanson
Published in: Current Opinion in Endocrine and Metabolic Research, 13, 2020, Page(s) 20-27, ISSN 2451-9650
Publisher: Elsevier Ltd.
DOI: 10.1016/j.coemr.2020.08.001

Paternal body mass index and offspring DNA methylation: findings from the PACE consortium

Author(s): Gemma C Sharp, Rossella Alfano, Akram Ghantous, Jose Urquiza, Sheryl L Rifas-Shiman, Christian M Page, Jianping Jin, Silvia Fernández-Barrés, Gillian Santorelli, Gwen Tindula, Gemma C Sharp, Rossella Alfano, Akram Ghantous, Jose Urquiza, Sheryl L Rifas-Shiman, Christian M Page, Jianping Jin, Silvia Fernández-Barrés, Gillian Santorelli, Gwen Tindula, Paul Yousefi, Leanne Kupers, Carlos Ruiz-Are
Published in: International Journal of Epidemiology, 2021, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyaa267

Duration and exclusiveness of breastfeeding and risk of childhood atopic diseases

Author(s): N. J. Elbert, E. R. van Meel, H. T. den Dekker, N. W. de Jong, T. E. C. Nijsten, V. W. V. Jaddoe, J. C. de Jongste, S. G. M. A. Pasmans, L. Duijts
Published in: Allergy, 72/12, 2017, Page(s) 1936-1943, ISSN 0105-4538
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/all.13195

What quantitative and qualitative methods have been developed to measure the implementation of a life-course approach in public health policies at the national level?

Author(s): Jacob CM, Cooper C, Baird J, Hanson M
Published in: WHO Health Evidence Network Synthesis Reports, 2019
Publisher: World Health Organisation