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CORDIS - Résultats de la recherche de l’UE
CORDIS

Early-life stressors and LifeCycle health

Livrables

Report on the relationships of early-life exposures with trajectories of cardiovascular and metabolic risk factors from birth to adulthood

We will study the associations of individual earlylife stressors and the integrated earlylife exposome with cardiometabolic phenotypes at various ages across the life course and with trajectories of those phenotypes

Report on differences in DNA methylation loci that mediate the associations of early-life exposures with mental health and psychopathology life course trajectories

We will identify DNA methylation loci that mediate the relationships of earlylife stressors and the integrated earlylife exposome with mental health and disease trajectories

Report on the associations of DNA methylation loci related to early-life stressors with functional outcomes, including RNA expression

We will explore associations of differences in DNA methylation at specific CpG sites discovered in EWAS with RNA expression levels methylationtranscription analyses using RNA expression data measured in some of the participating cohorts at various ages in childhood

Report on impact of early-life policies and interventions based on dynamic microsimulation models

Dynamic microsimulation modelling involves the generation of simulated data on individual units and is particularly suited for policy evaluations and scenario analyses It is a multiprocess simulation model in which each process is estimated at an individual level and feeds back into the other processes In LIFECYCLE the analytical framework and the specific models will be informed with populationspecific exposure prevalences and effect estimates of distal earlylife stressors and intermediates obtained from the EU Child Cohort Network and external data

Report on the associations of early-life stressors during preconception, pregnancy, infancy and early childhood with lung function developmental trajectories and the risk of asthma from childhood until young adulthood

We will use individual participant data from the EU Child Cohort Network to identify earlylife stressors individually and integrated in the earlylife exposome with lung function trajectories and symptoms diagnosis and medication related to asthma Main outcomes include lung function FEV1 FEV1FVC FEF2575 FEF75 bronchial hyperresponsiveness and symptoms and diseases respiratory infections wheezing asthma

Report on internalizing and externalizing behavior and other mental health trajectories from birth to childhood, and their associations with psychopathology outcomes

We will model longitudinal life course trajectories of mental function from early life to adulthood using data from the EU Child Cohort Network These trajectories will include both tracking and stability of internalizing and externalizing behavioural indicators measured with the Child Behaviour Check List CBCL throughout childhood and the relationships of these behavioural indicators with psychopathology indicators in adolescence and adulthood

Report on associations of early-life stressors with DNA methylation at birth

We will use an EWAS approach to study the associations of the main indicators of early-life stressors and the integrated early-life exposome, before and during pregnancy on DNA methylation at birth measured in cord blood. We will also explore the associations of the overall early-life exposome, developed in WP3, during pregnancy, on cord blood methylation at birth.

Report on review of interventions focused on lifestyle stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on lifestyle stressors of parents and young children. In line with WP3, these stressors will include parental smoking, alcohol consumption, illicit drug use, sleep, physical activity and parent and childhood nutritional intake and status.

Report on exposome models based on proof-of-principle studies

We will develop protocols for analysis of associations of a fully integrated earlylife stressor model the earlylife exposome with lifecycle health outcomes and test these in proofofprinciple studies As input we will use the main earlylife stressors WP1 WP3 Deliverable 31 34 Proofofprinciple datasets will be those of the EUFP7 funded HELIX project wwwprojecthelixeu including six cohorts across Europe n1200 plus the Generation R Study n7000 and DNBC n70000

Report on review of interventions focused on migration stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence on interventions on stressors related to migration. In line with WP3, the stressors will include indicators at individual, neighbourhood and macro-levels such as country of origin of the individual, its parents, or grandparents, generation after migration, measurements of integration.

Report on approaches to analyse multiple stressor data in the context of longitudinal modelling

In WP3 we will develop models to analyse associations of multiple stressors many of which are multidimensional with health outcomes This task will further develop these methods by assessing approaches to analyse multiple correlated stressor data in the context of longitudinal modelling

Report on the persistence of DNA methylation differences related to early-life stressors

To establish the role of DNA methylation differences on later life health outcomes in more detail and to better understand how these differences may exert effects, we will examine DNA methylation differences from birth to early adulthood in relation to early-life stressors.

Report on review of interventions focused on urban environment stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on urban environment stressors. In line with WP3, these stressors will include measurements of air pollution, noise, green space, connectivity and walkability.

Report on the effects of early-life stressors on mental health and psychopathology life course trajectories

We will use data from the EU Child Cohort Network to study the associations of earlylife stressors including socioeconomic migrant urban environment and lifestyle related indicators and the integrated earlylife exposome with mental development mental health and risk factors for psychiatric diseases at various ages across the life course

Recommendations for public health strategies focused on future parents and young children to improve life course health trajectories from early life onwards

We will develop recommendations for public health strategies based on findings from LIFECYCLE and systematic reviews of literature on interventions about modifications of earlylife stressors WP9

Report on early-life stressors that are related to both asthma throughout childhood and lung function and COPD in adulthood

We will explore whether individual earlylife stressors and the integrated earlylife exposome related to impaired respiratory health at younger age also affect lung function and risk of COPD in adulthood

Report on review of interventions focused on socio-economic stressors, to improve life course health trajectories

We will perform literature searches and reviews based on the developed strategies from deliverable 9.1. We will review evidence focused on interventions on socio-economic inequalities In line with WP3, socio-economic related stressors will include parental education, occupation, type of employment contract, family income, family size, child care and house property and size.

Report on cardiovascular developmental trajectories during fetal life, infancy and early childhood, and the relationship with early-life exposures and cardiovascular risk factors in childhood

We will use data from the EU Child Cohort Network partners that collected data before or during pregnancy and have detailed fetal and infant growth and cardiovascular development data. We will study associations of early-life stressors and the early-life exposome with adiposity and cardio-metabolic developmental trajectories in fetal life, infancy and early childhood (fetal and placental blood flow, cardiac and vascular dimensions, adiposity), and subsequently associations of these trajectories with risk factors for childhood for cardio-metabolic disease.

Report on the relationship of early-life exposures with differences in metabolic profiles and the extent to which these mediate associations of early-life exposures with cardio-metabolic risk factors and disease

We will explore the associations of individual earlylife stressors and the integrated earlylife exposome with a wide range of metabolites reflecting systemic metabolism that might mediate associations of earlylife exposures with subsequent cardiometabolic disease

Report on various life course models for the effects of early-life exposures on later cardio-metabolic risk factors and disease

In line with deliverable 41 and WP7 we will compare various potential life course models to best explain the relationships of earlylife stressors and potential mediators with trajectories of cardiometabolic risk factors and disease All EU Child Cohort Network cohorts will contribute to one or more of these trajectories

Report on DNA methylation changes as measures of early-life exposures

We will explore if DNA methylation patterns can be used as markers for earlylife stressors Building on deliverables 8184 we will assess if DNA methylation sites or patterns that are related to earlylife stressors are able to accurately identify those exposed ie specific enough to the exposure in question

Report on to what extent differences in DNA methylation mediate the associations between early-life stressors and subsequent life course chronic obstructive respiratory health and disease trajectories

We will identify DNA methylation loci that mediate the relationships of earlylife stressors with chronic obstructive respiratory health and disease throughout the life course We will use data from studies that have epigenomewide data on DNA methylation which can be used for epigenomewide association studies EWAS metaanalyses to identify epigenetic markers associated with respiratory outcomes

Integrated summary report on recommendations on potential interventions focused on modification of early-life stressors

We will integrate results from the reviews from deliverables 92 95 for recommendations for feasible effective and efficient interventions before or during pregnancy in infancy or in early childhood Specific subgroups of interest include socioeconomic and ethnic groups or subgroups identified at increased risk based on other parental or infant characteristics

Report on the relationships of early-life stressors with transient and persistent common allergies, and the extent to which these mediate associations of early-life stressors with life course chronic obstructive respiratory health and disease trajectories

We will relate individual earlylife stressors and the integrated earlylife exposome with common allergies from birth to young adulthood We will also examine if we can identify subgroups based on allergic and nonallergic pathways

Report on differences in DNA methylation loci that mediate the associations of early-life exposures with cardio-metabolic risk factors and disease

We will identify DNA methylation loci that mediate the associations of individual earlylife stressors and the integrated earlylife exposome with cardiometabolic risk factor trajectories and disease We will use data from studies that have epigenomewide data on DNA methylation which can be used for epigenomewide association studies EWAS metaanalyses to identify epigenetic markers associated with cardiometabolic outcomes

Report on approaches for longitudinal data/health trajectories in the context of life course analyses

We will provide a detailed description of analytical options to analyse repeated measurements data. We will cover theoretical biostatical aspects, the link between statistical modelling and the underlying biological frameworks and more practical applications dealing with issues of implementation and interpretation.

Report on patterns of core and integrated socio-economic, migration, urban environment and lifestyle related stressors across Europe

We will use all core and integrated data from WP3 deliverables 3.1 - 3.4 and apply factor analysis and model-based latent class analysis to uncover the nature of the underlying dependencies between stressors and to define stressor patterns. Participating partner cohorts are those that have collected key variables in each of the areas. Particular attention will be paid to comparing of stressor patterns between regions

Report on approaches for causal inference in the context of life course trajectory analyses

We will develop an analysis plan providing a detailed description of options in study design and statistical analyses to apply causal inference methods to life course research. This will integrate theoretical and applied aspects, focusing on implementation and interpretation.

Report on the impact of early-life stressors on population and individual economic outcomes

We will identify links between earlylife stressors and economically related later life outcomes and elucidate mechanisms underlying these links We will use longitudinal data from the EU Child Cohort Network by linking earlylife stressors to economicallyrelated outcomes in childhood adolescence and adulthood Next we will use registrybased data from Statistics Netherlands CBS and Statistics Finland to relate earlylife stressors such as recessions to economically related outcomes later in life

Report on the relationship of early-life stressors with fetal and childhood brain developmental outcomes and the extent to which these mediate associations of early-life exposures with mental health and psychopathology life course trajectories

We will study brain development from the fetal period and childhood onwards by means of advanced imaging studies including repeated fetal ultrasound and childhood MRI brain studies We will first study the role of brain developmental adaptations in fetal life or childhood Generation R Generation R Next INMA ALSPAC BIB NFBC1986 RAINE and subsequently try to replicate the findings in adults NFBC1966 This deliverable will provide insights to the role of developmental structural and functional brain developmental adaptations in the relationships between earlylife stressors and mental health trajectories

eHealth applications for personalized prevention strategies

We will maximize the impact of the main results for individuals by developing a website and mobile applications for individually customized advice to women and men before pregnancy and for pregnant women and young children

External project website launched

Project website accessible for general public and specific public. The website will be multi-layered. The homepage will be accessible to everyone; it will be based mainly on visual communication (videoclips, data visualisations, etc.); and it will link to specific pages for various stakeholder or target groups, including researchers, health care providers, patient organizations, patients and policymakers.

Publications

Longitudinal associations of DNA methylation and sleep in children: a meta-analysis

Auteurs: S. Sammallahti, M. E. Koopman-Verhoeff, A. C. Binter, R. H. Mulder, A. Cabre-Riera, T. Kvist, et al.
Publié dans: Clin Epigenetics, Numéro 18687075, 2022, ISSN 1868-7075
Éditeur: Springer Verlag
DOI: 10.1186/s13148-022-01298-4

Prenatal maternal and cord blood vitamin D concentrations and negative affectivity in infancy

Auteurs: S. Sammallahti, E. Holmlund-Suila, R. Zou, S. Valkama, J. Rosendahl, M. Enlund-Cerullo, et al.
Publié dans: Eur Child Adolesc Psychiatry, Numéro 10188827, 2021, ISSN 1018-8827
Éditeur: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00787-021-01894-4

Associations of physical condition with lung function and asthma in adolescents from the general population

Auteurs: S. M. Mensink-Bout, M. R. Jahangir, J. C. de Jongste, H. Raat, V. W. V. Jaddoe and L. Duijts
Publié dans: Pediatr Allergy Immunol, Numéro 09056157, 2022, ISSN 0905-6157
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/pai.13811

Associations of Hair Cortisol Concentrations With Cardiometabolic Risk Factors in Childhood

Auteurs: Florianne O L Vehmeijer, Susana Santos, Yolanda B de Rijke, Erica L T van den Akker, Janine F Felix, Elisabeth F C van Rossum, Vincent W V Jaddoe
Publié dans: The Journal of Clinical Endocrinology & Metabolism, Numéro 106/9, 2021, Page(s) e3400-e3413, ISSN 0021-972X
Éditeur: The Endocrine Society
DOI: 10.1210/clinem/dgab379

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia

Auteurs: J. Auvinen, J. Tapio, V. Karhunen, J. Kettunen, R. Serpi, E. Y. Dimova, et al.
Publié dans: Sci Adv, Numéro 23752548, 2021, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abi4822

Influence of maternal vomiting during early pregnancy on school-age respiratory health

Auteurs: S. D. Poeran-Bahadoer, E. R. van Meel, R. Gaillard, V. W. V. Jaddoe and L. Duijts
Publié dans: Pediatr Pulmonol, Numéro 10990496, 2022, ISSN 1099-0496
Éditeur: Wiley-Liss Inc.
DOI: 10.1002/ppul.25747

Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

Auteurs: S. Vogelezang, J. P. Bradfield, C. Early Growth Genetics, S. F. A. Grant, J. F. Felix and V. W. V. Jaddoe
Publié dans: BMC Med Genomics, Numéro 17558794, 2022, ISSN 1755-8794
Éditeur: BioMed Central
DOI: 10.1186/s12920-022-01281-1

The link between attention deficit hyperactivity disorder (ADHD) symptoms and obesity-related traits: genetic and prenatal explanations

Auteurs: V. Karhunen, T. A. Bond, V. Zuber, T. Hurtig, I. Moilanen, M. R. Jarvelin, et al.
Publié dans: Transl Psychiatry, Numéro 21583188, 2021, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-021-01584-4

Genome‐wide DNA methylation patterns associated with sleep and mental health in children: a population‐based study

Auteurs: Maria Elisabeth Koopman‐Verhoeff, Rosa H. Mulder, Jared M. Saletin, Irwin Reiss, Gijsbertus T.J. Horst, Janine F. Felix, Mary A. Carskadon, Henning Tiemeier, Charlotte A.M. Cecil
Publié dans: Journal of Child Psychology and Psychiatry, Numéro 61/10, 2020, Page(s) 1061-1069, ISSN 0021-9630
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/jcpp.13252

Early-life famine exposure, hunger recall, and later-life health

Auteurs: Z. Deng, M. Lindeboom
Publié dans: Journal of Applied Econometrics, Numéro 08837252, 2022, ISSN 0883-7252
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jae.2897

Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

Auteurs: Edwina H. Yeung, Weihua Guan, Xuehuo Zeng, Lucas A. Salas, Sunni L. Mumford, Paula de Prado Bert, Evelien R. van Meel, Anni Malmberg, Jordi Sunyer, Liesbeth Duijts, Janine F. Felix, Darina Czamara, Esa Hämäläinen, Elisabeth B. Binder, Katri Räikkönen, Jari Lahti, Stephanie J. London, Robert M. Silver, Enrique F. Schisterman
Publié dans: Clinical Epigenetics, Numéro 12/1, 2020, ISSN 1868-7075
Éditeur: Springer Verlag
DOI: 10.1186/s13148-020-00852-2

Prevention of noncommunicable diseases by interventions in the preconception period: A FIGO position paper for action by healthcare practitioners

Auteurs: Chandni Maria Jacob, Sarah Louise Killeen, Fionnuala M. McAuliffe, Judith Stephenson, Moshe Hod, Ivonne Diaz Yamal, Jaideep Malhotra, Edgar Mocanu, H. David McIntyre, Anne B. Kihara, Ronald C. Ma, Hema Divakar, Anil Kapur, Rui Ferriani, Ernest Ng, Laurie Henry, Zephne Van Der Spuy, Zev Rosenwaks, Mark A. Hanson
Publié dans: International Journal of Gynecology & Obstetrics, Numéro 151/S1, 2020, Page(s) 6-15, ISSN 0020-7292
Éditeur: Elsevier BV
DOI: 10.1002/ijgo.13331

Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study

Auteurs: Giulietta S. Monasso, Leanne K. Küpers, Vincent W. V. Jaddoe, Sandra G. Heil, Janine F. Felix
Publié dans: Clinical Epigenetics, Numéro 13/1, 2021, ISSN 1868-7075
Éditeur: Springer Verlag
DOI: 10.1186/s13148-021-01065-x

The relationship of life-course patterns of adiposity with type 2 diabetes, depression, and their comorbidity in the Northern Finland Birth Cohort 1966

Auteurs: P. Choudhary, J. Ronkainen, R. Nedelec, M. Tolvanen, E. Lowry, J. Miettunen, et al.
Publié dans: Int J Obes (Lond), Numéro 03070565, 2022, ISSN 0307-0565
Éditeur: Nature Publishing Group
DOI: 10.1038/s41366-022-01134-y

Associations of maternal and infant metabolite profiles with foetal growth and the odds of adverse birth outcomes

Auteurs: E. Voerman, V. W. V. Jaddoe, E. Shokry, G. J. G. Ruijter, J. F. Felix, B. Koletzko, et al.
Publié dans: Pediatr Obes, Numéro 20476310, 2022, ISSN 2047-6310
Éditeur: Wiley-Blackwell for the International Association for the Study of Obesity
DOI: 10.1111/ijpo.12844

Large-scale association analyses identify host factors influencing human gut microbiome composition

Auteurs: Alexander Kurilshikov, Carolina Medina-Gomez, Rodrigo Bacigalupe, Djawad Radjabzadeh, Jun Wang, Ayse Demirkan, Caroline I. Le Roy, Juan Antonio Raygoza Garay, Casey T. Finnicum, Xingrong Liu, Daria V. Zhernakova, Marc Jan Bonder, Tue H. Hansen, Fabian Frost, Malte C. Rühlemann, Williams Turpin, Jee-Young Moon, Han-Na Kim, Kreete Lüll, Elad Barkan, Shiraz A. Shah, Myriam Fornage, Joanna Szopinska
Publié dans: Nature Genetics, Numéro 53/2, 2021, Page(s) 156-165, ISSN 1061-4036
Éditeur: Nature Publishing Group
DOI: 10.1038/s41588-020-00763-1

Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium

Auteurs: Justiina Ronkainen, Anni Heiskala, Florianne O.L. Vehmeijer, Estelle Lowry, Doretta Caramaschi, Guadalupe Estrada Gutierrez, Jonathan A. Heiss, Nadine Hummel, Elina Keikkala, Tuomas Kvist, Allison Kupsco, Phillip E. Melton, Giancarlo Pesce, Munawar H. Soomro, Marta Vives-Usano, Nour Baiz, Elisabeth Binder, Darina Czamara, Mònica Guxens, Sanna Mustaniemi, Stephanie J. London, Sebastian Rauschert,
Publié dans: Epigenetics, 2021, Page(s) 1-13, ISSN 1559-2294
Éditeur: Landes Bioscience
DOI: 10.1080/15592294.2020.1864171

Maternal iron status in early pregnancy and DNA methylation in offspring: an epigenome-wide meta-analysis

Auteurs: M. J. Taeubert, P. de Prado-Bert, M. L. Geurtsen, G. Mancano, M. J. Vermeulen, I. K. M. Reiss, et al.
Publié dans: Clin Epigenetics, Numéro 18687075, 2022, ISSN 1868-7075
Éditeur: Springer Verlag
DOI: 10.1186/s13148-022-01276-w

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

Auteurs: Alexander Neumann, Esther Walton, Silvia Alemany, Charlotte Cecil, Juan Ramon González, Dereje D. Jima, Jari Lahti, Samuli T. Tuominen, Edward D. Barker, Elisabeth Binder, Doretta Caramaschi, Ángel Carracedo, Darina Czamara, Jorunn Evandt, Janine F. Felix, Bernard F. Fuemmeler, Kristine B. Gutzkow, Cathrine Hoyo, Jordi Julvez, Eero Kajantie, Hannele Laivuori, Rachel Maguire, Léa Maitre, Susan K
Publié dans: Translational Psychiatry, Numéro 10/1, 2020, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-020-01058-z

Urban environment and health behaviours in children from six European countries

Auteurs: S. Fernandez-Barres, O. Robinson, S. Fossati, S. Marquez, X. Basagana, J. de Bont, et al.
Publié dans: Environ Int, Numéro 01604120, 2022, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107319

Fibre Intake Is Associated with Cardiovascular Health in European Children

Auteurs: Susana Larrosa, Veronica Luque, Veit Grote, Ricardo Closa-Monasterolo, Natalia Ferré, Berthold Koletzko, Elvira Verduci, Dariusz Gruszfeld, Annick Xhonneux, Joaquin Escribano
Publié dans: Nutrients, Numéro 13/1, 2021, Page(s) 12, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13010012

Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

Auteurs: R.C. Huang, P.E. Melton, M.A. Burton, L.J. Beilin, R Clarke-Harris, E Cook, K.M. Godfrey, G.C. Burdge, T.A. Mori, D Anderson, S. Rauschert, J. M. Craig, M.S. Kobor, J.L. MacIsaac, A.M. Morin, W.H. Oddy, C.E. Pennell, J.D. Holbrook, K.A. Lillycrop
Publié dans: Epigenetics, 2021, Page(s) 1-18, ISSN 1559-2294
Éditeur: Landes Bioscience
DOI: 10.1080/15592294.2021.1876297

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills

Auteurs: D. Caramaschi, A. Neumann, A. Cardenas, G. Tindula, S. Alemany, L. Zillich, et al.
Publié dans: Mol Psychiatry, Numéro 13594184, 2022, ISSN 1359-4184
Éditeur: Nature Publishing Group
DOI: 10.1038/s41380-022-01441-w

Applying the exposome concept in birth cohort research: a review of statistical approaches

Auteurs: Susana Santos, Léa Maitre, Charline Warembourg, Lydiane Agier, Lorenzo Richiardi, Xavier Basagaña, Martine Vrijheid
Publié dans: European Journal of Epidemiology, Numéro 35/3, 2020, Page(s) 193-204, ISSN 0393-2990
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10654-020-00625-4

Acceptability of the FIGO Nutrition Checklist in Preconception and Early Pregnancy to Assess Nutritional Status and Prevent Excess Gestational Weight Gain: A Study of Women and Healthcare Practitioners in the UK

Auteurs: C. M. Jacob, H. M. Inskip, W. Lawrence, C. McGrath, F. M. McAuliffe, S. L. Killeen, et al.
Publié dans: Nutrients, Numéro 20726643, 2022, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14173623

Associations of Plasma Fatty Acid Patterns during Pregnancy with Respiratory and Allergy Outcomes at School Age

Auteurs: Sara M. Mensink-Bout, Trudy Voortman, Marsela Dervishaj, Irwin K. M. Reiss, Johan C. De Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Publié dans: Nutrients, Numéro 12/10, 2020, Page(s) 3057, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12103057

Measuring Child Socio-Economic Position in Birth Cohort Research: The Development of a Novel Standardized Household Income Indicator

Auteurs: Costanza Pizzi, Matteo Richiardi, Marie-Aline Charles, Barbara Heude, Jean-Louis Lanoe, Sandrine Lioret, Sonia Brescianini, Virgilia Toccaceli, Martine Vrijheid, Franco Merletti, Daniela Zugna, Lorenzo Richiardi
Publié dans: International Journal of Environmental Research and Public Health, Numéro 17/5, 2020, Page(s) 1700, ISSN 1660-4601
Éditeur: MDPI
DOI: 10.3390/ijerph17051700

Global e-Learning in Early Nutrition and Lifestyle for International Healthcare Professionals: Design and Evaluation of the Early Nutrition Specialist Programme (ENS)

Auteurs: Brigitte Brands, Ngoc Nhan Tran, Erin Baudendistel-Happ, Marina Sanchez-Garcia, Martin R. Fischer, Berthold Koletzko
Publié dans: Nutrients, Numéro 13/3, 2021, Page(s) 775, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13030775

Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium

Auteurs: Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Mark Hanson, Keith M. Godfrey, Romy Gaillard, Liesbeth Duijts, Barbara Heude, James R. Hébert, Fionnuala M. McAuliffe, Cecily C.
Publié dans: BMC Medicine, Numéro 19/1, 2021, ISSN 1741-7015
Éditeur: BioMed Central
DOI: 10.1186/s12916-021-01908-7

Most associations of early‐life environmental exposures and genetic risk factors poorly differentiate between eczema phenotypes: the Generation R Study

Auteurs: C. Hu, L. Duijts, N.S. Erler, N.J. Elbert, C. Piketty, V. Bourdès, S. Blanchet‐Réthoré, J.C. Jongste, S.G.M.A. Pasmans, J.F. Felix, T. Nijsten
Publié dans: British Journal of Dermatology, Numéro 181/6, 2019, Page(s) 1190-1197, ISSN 0007-0963
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/bjd.17879

Neonatal DNA methylation and childhood low prosocial behavior: An epigenome‐wide association meta‐analysis

Auteurs: Mannan Luo, Alan J. Meehan, Esther Walton, Stefan Röder, Gunda Herberth, Ana C. Zenclussen, Marta Cosín‐Tomás, Jordi Sunyer, Rosa H. Mulder, Andrea P. Cortes Hidalgo, Marian J. Bakermans‐Kranenburg, Janine F. Felix, Caroline Relton, Matthew Suderman, Irene Pappa, Rianne Kok, Henning Tiemeier, Marinus H. IJzendoorn, Edward D. Barker, Charlotte A. M. Cecil
Publié dans: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Numéro 186/4, 2021, Page(s) 228-241, ISSN 1552-4841
Éditeur: Wiley-Liss Inc
DOI: 10.1002/ajmg.b.32862

DNA methylation patterns within whole blood of adolescents born from assisted reproductive technology are not different from adolescents born from natural conception

Auteurs: B Penova-Veselinovic, P E Melton, R C Huang, J L Yovich, P Burton, L A Wijs, R J Hart
Publié dans: Human Reproduction, Numéro 36/7, 2021, Page(s) 2035-2049, ISSN 0268-1161
Éditeur: Oxford University Press
DOI: 10.1093/humrep/deab078

Building resilient societies after COVID-19: the case for investing in maternal, neonatal, and child health

Auteurs: Chandni Maria Jacob, Despina D Briana, Gian Carlo Di Renzo, Neena Modi, Flavia Bustreo, Gabriella Conti, Ariadne Malamitsi-Puchner, Mark Hanson
Publié dans: The Lancet Public Health, Numéro 5/11, 2020, Page(s) e624-e627, ISSN 2468-2667
Éditeur: Elsevier Ltd.
DOI: 10.1016/s2468-2667(20)30200-0

Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis

Auteurs: Hugo G. Quezada-Pinedo, Florian Cassel, Liesbeth Duijts, Martina U. Muckenthaler, Max Gassmann, Vincent W. V. Jaddoe, Irwin K. M. Reiss, Marijn J. Vermeulen
Publié dans: Nutrients, Numéro 13/7, 2021, Page(s) 2221, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13072221

Health of women and children is central to covid-19 recovery

Auteurs: Neena Modi, Mark Hanson
Publié dans: BMJ, 2021, Page(s) n899, ISSN 1756-1833
Éditeur: BMJ
DOI: 10.1136/bmj.n899

The preconception period as a platform for preventing diabetes and non-communicable diseases

Auteurs: C. M. Jacob, M. Hanson
Publié dans: Practical Diabetes, Numéro 20472897, 2022, ISSN 2047-2897
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/pdi.2404

Sleep duration and problem behaviour in 8-year-old children in the Childhood Obesity Project

Auteurs: Kathrin Guerlich, Dariusz Gruszfeld, Justyna Czech-Kowalska, Natàlia Ferré, Ricardo Closa-Monasterolo, Françoise Martin, Pascale Poncelet, Elvira Verduci, Berthold Koletzko, Veit Grote
Publié dans: European Child & Adolescent Psychiatry, 2021, ISSN 1018-8827
Éditeur: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00787-021-01731-8

Effect of Maternal Prepregnancy/Early‐Pregnancy Body Mass Index and Pregnancy Smoking and Alcohol on Congenital Heart Diseases: A Parental Negative Control Study

Auteurs: Kurt Taylor, Ahmed Elhakeem, Johanna Lucia Thorbjørnsrud Nader, Tiffany C. Yang, Elena Isaevska, Lorenzo Richiardi, Tanja Vrijkotte, Angela Pinot de Moira, Deirdre M. Murray, Daragh Finn, Dan Mason, John Wright, Sam Oddie, Nel Roeleveld, Jennifer R. Harris, Anne‐Marie Nybo Andersen, Massimo Caputo, Deborah A. Lawlor
Publié dans: Journal of the American Heart Association, Numéro 10/11, 2021, ISSN 2047-9980
Éditeur: Wiley-Blackwell
DOI: 10.1161/jaha.120.020051

Total Fatty Acid and Polar Lipid Species Composition of Human Milk

Auteurs: Talat Bashir Ahmed, Merete Eggesbø, Rachel Criswell, Olaf Uhl, Hans Demmelmair, Berthold Koletzko
Publié dans: Nutrients, Numéro 20726643, 2022, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14010158

Impact of Treatment with RUTF on Plasma Lipid Profiles of Severely Malnourished Pakistani Children

Auteurs: Engy Shokry, Kamran Sadiq, Sajid Soofi, Atif Habib, Naveed Bhutto, Arjumand Rizvi, Imran Ahmad, Hans Demmelmair, Olaf Uhl, Zulfiqar Bhutta, Berthold Koletzko
Publié dans: Nutrients, Numéro 12/7, 2020, Page(s) 2163, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12072163

Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

Auteurs: Oliver Robinson, Marc Chadeau Hyam, Ibrahim Karaman, Rui Climaco Pinto, Mika Ala-Korpela, Evangelos Handakas, Giovanni Fiorito, He Gao, Andy Heard, Marjo‐Riitta Jarvelin, Matthew Lewis, Raha Pazoki, Silvia Polidoro, Ioanna Tzoulaki, Matthias Wielscher, Paul Elliott, Paolo Vineis
Publié dans: Aging Cell, Numéro 19/6, 2020, ISSN 1474-9718
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/acel.13149

Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries

Auteurs: Jordi Julvez, Mónica López-Vicente, Charline Warembourg, Lea Maitre, Claire Philippat, Kristine B. Gützkow, Monica Guxens, Jorunn Evandt, Sandra Andrusaityte, Miguel Burgaleta, Maribel Casas, Leda Chatzi, Montserrat de Castro, David Donaire-González, Regina Gražulevičienė, Carles Hernandez-Ferrer, Barbara Heude, Rosie Mceachan, Mark Mon-Williams, Mark Nieuwenhuijsen, Oliver Robinson, Amrit
Publié dans: Environmental Pollution, Numéro 284, 2021, Page(s) 117404, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2021.117404

Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium

Auteurs: L. K. Kupers, S. Fernandez-Barres, A. Nounu, C. Friedman, R. Fore, G. Mancano, et al.
Publié dans: Epigenetics, Numéro 15592294, 2022, ISSN 1559-2294
Éditeur: Landes Bioscience
DOI: 10.1080/15592294.2022.2038412

New guidelines, position paper, and insights from the FIGO Pregnancy Obesity and Nutrition Initiative (PONI)

Auteurs: Mark A. Hanson, Fionnuala M. McAuliffe, Sarah Louise Killeen, Chandni Maria Jacob, Moshe Hod
Publié dans: International Journal of Gynecology & Obstetrics, Numéro 151/S1, 2020, Page(s) 1-3, ISSN 0020-7292
Éditeur: Elsevier BV
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Urban environment during early-life and blood pressure in young children

Auteurs: Charline Warembourg, Mark Nieuwenhuijsen, Ferran Ballester, Montserrat de Castro, Leda Chatzi, Ana Esplugues, Barbara Heude, Léa Maitre, Rosemary McEachan, Oliver Robinson, Rémy Slama, Jordi Sunyer, Jose Urquiza, John Wright, Xavier Basagaña, Martine Vrijheid
Publié dans: Environment International, Numéro 146, 2021, Page(s) 106174, ISSN 0160-4120
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Parental migrant status and health inequalities at birth: The role of immigrant educational selectivity

Auteurs: Sandra Florian, Mathieu Ichou, Lidia Panico
Publié dans: Social Science & Medicine, Numéro 278, 2021, Page(s) 113915, ISSN 0277-9536
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Cardio‐metabolic risk factors during childhood in relation to lung function and asthma

Auteurs: Sara M. Mensink‐Bout, Susana Santos, Johan C. Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Publié dans: Pediatric Allergy and Immunology, Numéro 32/5, 2021, Page(s) 945-952, ISSN 0905-6157
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First trimester fetal proportion volumetric measurements using a Virtual Reality approach

Auteurs: Clarissa J. Wiertsema, Jan S. Erkamp, Annemarie G. M. G. J. Mulders, Eric A. P. Steegers, Liesbeth Duijts, Anton H. J. Koning, Romy Gaillard, Vincent W. V. Jaddoe
Publié dans: Prenatal Diagnosis, Numéro 41/7, 2021, Page(s) 868-876, ISSN 0197-3851
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Associations of eczema phenotypes with emotional and behavioural problems from birth until school age. The Generation R Study

Auteurs: C. Hu, T. Nijsten, S.G.M.A. Pasmans, J.C. Jongste, P.W. Jansen, L. Duijts
Publié dans: British Journal of Dermatology, Numéro 183/2, 2020, Page(s) 311-320, ISSN 0007-0963
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Associations of maternal early-pregnancy blood glucose and insulin concentrations with DNA methylation in newborns

Auteurs: Madelon L. Geurtsen, Vincent W. V. Jaddoe, Romy Gaillard, Janine F. Felix
Publié dans: Clinical Epigenetics, Numéro 12/1, 2020, ISSN 1868-7075
Éditeur: Springer Verlag
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Acute Metabolic Response in Adults to Toddler Milk Formulas with Alternating Higher and Lower Protein and Fat Contents, a Randomized Cross-Over Trial

Auteurs: E. Newton-Tanzer, H. Demmelmair, J. Horak, L. Holdt, B. Koletzko and V. Grote
Publié dans: Nutrients, Numéro 20726643, 2021, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Vitamin B12, folate and homocysteine concentrations during pregnancy and early signs of atherosclerosis at school-age

Auteurs: G. S. Monasso, J. F. Felix, S. G. Heil, Y. B. de Rijke, R. Gaillard and V. W. V. Jaddoe
Publié dans: Clin Nutr, Numéro 02615614, 2021, ISSN 0261-5614
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DOI: 10.1016/j.clnu.2021.08.001

Development of a prediction model to target screening for high blood pressure in children

Auteurs: Marleen Hamoen, Marieke Welten, Daan Nieboer, Guannan Bai, Martijn W. Heymans, Jos W.R. Twisk, Hein Raat, Yvonne Vergouwe, Alet H. Wijga, Marlou L.A. de Kroon
Publié dans: Preventive Medicine, Numéro 132, 2020, Page(s) 105997, ISSN 0091-7435
Éditeur: Academic Press
DOI: 10.1016/j.ypmed.2020.105997

Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomisation using polygenic risk scores

Auteurs: T. A. Bond, R. C. Richmond, V. Karhunen, G. Cuellar-Partida, M. C. Borges, V. Zuber, et al.
Publié dans: BMC Med, Numéro 17417015, 2022, ISSN 1741-7015
Éditeur: BioMed Central
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Higher carotid-radial pulse wave velocity is associated with non-melancholic depressive symptoms in men – findings from Helsinki Birth Cohort Study

Auteurs: Mia D. Eriksson, Johan G. Eriksson, Hannu Kautiainen, Minna K. Salonen, Tuija M. Mikkola, Eero Kajantie, Niko Wasenius, Mikaela von Bonsdorff, Päivi Korhonen, Merja K. Laine
Publié dans: Annals of Medicine, Numéro 53/1, 2021, Page(s) 531-540, ISSN 0785-3890
Éditeur: Taylor & Francis
DOI: 10.1080/07853890.2021.1904277

Association of self-reported polycystic ovary syndrome, obesity, and weight gain from adolescence to adulthood with hypertensive disorders of pregnancy:a community-based approach

Auteurs: Rantakallio, J. S. (Juhani S.S.); Nevalainen, J. E. (Jaana E.); West, S. I. (Sammeli I.); Ollila, M.-M. (Meri-Maija); Puukka, K. (Katri); Bloigu, A. H. (Aini H.); Järvelin, M.-R. (Marjo-Riitta); Tapanainen, J. S. (Juha S.); Franks, S. (Stephen); Dunkel, L. (Leo); Piltonen, T. T. (Terhi T.); Vääräsmäki, M. S. (Marja S.); Morin-Papunen, L. C. (Laure C.)
Publié dans: Hypertension, Numéro 0194911X, 2021, ISSN 0194-911X
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.15702

DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium

Auteurs: M. Lozano, P. Yousefi, K. Broberg, R. Soler-Blasco, C. Miyashita, G. Pesce, et al.
Publié dans: Environ Res, Numéro 00139351, 2022, ISSN 0013-9351
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DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

Auteurs: Florianne O. L. Vehmeijer, Leanne K. Küpers, Gemma C. Sharp, Lucas A. Salas, Samantha Lent, Dereje D. Jima, Gwen Tindula, Sarah Reese, Cancan Qi, Olena Gruzieva, Christian Page, Faisal I. Rezwan, Philip E. Melton, Ellen Nohr, Geòrgia Escaramís, Peter Rzehak, Anni Heiskala, Tong Gong, Samuli T. Tuominen, Lu Gao, Jason P. Ross, Anne P. Starling, John W. Holloway, Paul Yousefi, Gunn Marit Aasvang,
Publié dans: Genome Medicine, Numéro 12/1, 2020, ISSN 1756-994X
Éditeur: BioMed Central
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Joint associations of parental personality traits and socioeconomic position with trajectories of offspring depression: findings from up to 6925 families in a UK birth cohort.

Auteurs: Tim Cadman; Alex S. F. Kwong; Paul Moran; Heather O’Mahen; Iryna Culpin; Debbie A Lawlor; Rebecca M. Pearson
Publié dans: JCPP Advances, Vol 1, Iss 3, Pp n/a-n/a (2021), Numéro 26929384, 2021, ISSN 2692-9384
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Technical challenges of quantitative chest MRI data analysis in a large cohort pediatric study

Auteurs: Anh H. Nguyen; Adria Perez-Rovira; Piotr A. Wielopolski; Juan A. Hernandez Tamames; Liesbeth Duijts; Marleen de Bruijne; Marleen de Bruijne; Andrea Aliverti; Francesca Pennati; Tetyana Ivanovska; Harm A.W.M. Tiddens; Pierluigi Ciet
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Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations

Auteurs: Fernando Pires Hartwig, Kate Tilling, George Davey Smith, Deborah A Lawlor, Maria Carolina Borges
Publié dans: International Journal of Epidemiology, 2021, ISSN 0300-5771
Éditeur: Oxford University Press
DOI: 10.1093/ije/dyaa266

Association between nasal and nasopharyngeal bacterial colonization in early life and eczema phenotypes

Auteurs: Chen Hu, Liesbeth Duijts, Evelien R. Meel, Kirsten I. M. Looman, Jessica C. Kiefte‐de Jong, Luba M. Pardo, DirkJan Hijnen, Suzanne G. M. A. Pasmans, Johan C. Jongste, Henriette A. Moll, Tamar Nijsten
Publié dans: Clinical & Experimental Allergy, Numéro 51/5, 2021, Page(s) 716-725, ISSN 0954-7894
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cea.13869

Associations Between Intake of Sugar‐Containing Beverages in Infancy With Liver Fat Accumulation at School Age

Auteurs: Madelon L. Geurtsen, Susana Santos, Romy Gaillard, Janine F. Felix, Vincent W. V. Jaddoe
Publié dans: Hepatology, Numéro 73/2, 2021, Page(s) 560-570, ISSN 0270-9139
Éditeur: John Wiley & Sons Inc.
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Association of Assisted Reproductive Technology With Offspring Growth and Adiposity From Infancy to Early Adulthood

Auteurs: A. Elhakeem, A. E. Taylor, H. M. Inskip, J. Huang, M. Tafflet, J. L. Vinther, et al.
Publié dans: JAMA Netw Open, Numéro 25743805, 2022, ISSN 2574-3805
Éditeur: American Medical Association
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Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project - EU Child Cohort Network

Auteurs: J. L. Nader, M. Lopez-Vicente, J. Julvez, M. Guxens, T. Cadman, A. Elhakeem, et al.
Publié dans: J Epidemiol, Numéro 09175040, 2021, ISSN 0917-5040
Éditeur: Tokyo University of Agriculture
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Allergenic food introduction and risk of childhood atopic diseases

Auteurs: Niels J. Elbert, Jessica C. Kiefte-de Jong, Trudy Voortman, Tamar E. C. Nijsten, Nicolette W. de Jong, Vincent W. V. Jaddoe, Johan C. de Jongste, Roy Gerth van Wijk, Liesbeth Duijts, Suzanne G. M. A. Pasmans
Publié dans: PLOS ONE, Numéro 12/11, 2017, Page(s) e0187999, ISSN 1932-6203
Éditeur: Public Library of Science
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Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis of 229,000 singleton births

Auteurs: Elise M. Philips, Susana Santos, Leonardo Trasande, Juan J. Aurrekoetxea, Henrique Barros, Andrea von Berg, Anna Bergström, Philippa K. Bird, Sonia Brescianini, Carol Ní Chaoimh, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Nathalie Costet, Rachel Criswell, Sarah Crozier, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Marleen M. H. J. van Gelder
Publié dans: PLOS Medicine, Numéro 17/8, 2020, Page(s) e1003182, ISSN 1549-1676
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Infant weight growth patterns, childhood BMI, and arterial health at age 10 years

Auteurs: G. S. Monasso, C. C. V. Silva, S. Santos, R. Goncalvez, R. Gaillard, J. F. Felix, et al.
Publié dans: Obesity (Silver Spring), Numéro 19307381, 2022, ISSN 1930-7381
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Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study

Auteurs: Saranya Palaniswamy, Dipender Gill, N Maneka De Silva, Estelle Lowry, Jari Jokelainen, Toni Karhu, Shivaprakash J Mutt, Abbas Dehghan, Eeva Sliz, Daniel I Chasman, Markku Timonen, Heimo Viinamäki, Sirkka Keinänen-Kiukaanniemi, Elina Hyppönen, Karl-Heinz Herzig, Sylvain Sebert, Marjo-Riitta Järvelin
Publié dans: The American Journal of Clinical Nutrition, Numéro 111/5, 2020, Page(s) 1036-1047, ISSN 0002-9165
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Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

Auteurs: O. Solomon, K. Huen, P. Yousefi, L. K. Kupers, J. R. Gonzalez, M. Suderman, et al.
Publié dans: Mutat Res Rev Mutat Res, Numéro 13835742, 2022, ISSN 1383-5742
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Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study

Auteurs: Tuija M. Mikkola, Hannu Kautiainen, Mikaela B. von Bonsdorff, Minna K. Salonen, Niko Wasenius, Eero Kajantie, Johan G. Eriksson
Publié dans: Quality of Life Research, Numéro 29/8, 2020, Page(s) 2039-2050, ISSN 0962-9343
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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Auteurs: Suzanne Vogelezang, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo A. Lakka, Niels Grarup, Markus Scholz, Peter J. van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O. Fedko, Natalia Vilor-Tejedor, Diana L. Cousminer, Marie Standl, Carol A. Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bace
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Body fat, pericardial fat, liver fat and arterial health at age 10 years

Auteurs: G. S. Monasso, S. Santos, C. C. V. Silva, M. L. Geurtsen, E. Oei, R. Gaillard, et al.
Publié dans: Pediatr Obes, Numéro 20476310, 2022, ISSN 2047-6310
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Increased Th22 cell numbers in a general pediatric population with filaggrin haploinsufficiency: The Generation R Study

Auteurs: Kirsten I. M. Looman, Minke M. F. Mierlo, Menno C. Zelm, Chen Hu, Liesbeth Duijts, Johan C. Jongste, Tamar Nijsten, Luba M. Pardo, Jessica C. Kiefte‐de Jong, Henriëtte A. Moll, Suzanne G. M. A. Pasmans
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The role of school enjoyment and connectedness in the association between depressive and externalising symptoms and academic attainment: Findings from a UK prospective cohort study.

Auteurs: Tim Cadman; Amanda Hughes; Caroline F. Wright; José A López-López; Tim T Morris; Frances Rice; George Davey Smith; Laura D Howe
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Maternal and infant prediction of the child BMI trajectories; studies across two generations of Northern Finland birth cohorts

Auteurs: Rozenn Nedelec, Jouko Miettunen, Minna Männikkö, Marjo-Riitta Järvelin, Sylvain Sebert
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Living environment and its relationship to depressive mood: A systematic review

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Socioeconomic inequalities in reproductive outcomes in the Italian NINFEA birth cohort and the Piedmont Birth Registry

Auteurs: Pizzi, C; Popovic, M; Isaevska, E; Rusconi, F; Moirano, G; Merletti, F; Richiardi, L
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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies

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Associations of Fat and Lean Body Mass with Circulating Amino Acids in Older Men and Women

Auteurs: Tuija M Mikkola, Minna K Salonen, Eero Kajantie, Hannu Kautiainen, Johan G Eriksson
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Does smoking during pregnancy mediate educational disparities in preterm delivery? Findings from three large birth cohorts

Auteurs: Gry Poulsen, Anne‐Marie Nybo Andersen, Vincent W. V. Jaddoe, Per Magnus, Hein Raat, Camilla Stoltenberg, Merete Osler, Laust Hvas Mortensen
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Maternal iron status during early pregnancy and school‐age, lung function, asthma, and allergy: The Generation R Study

Auteurs: Hugo G. Quezada‐Pinedo, Sara M. Mensink‐Bout, Irwin K. Reiss, Vincent W. V. Jaddoe, Marijn J. Vermeulen, Liesbeth Duijts
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Developmental Origins of Health and Disease, resilience and social justice in the COVID era

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Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

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Associations of maternal dietary inflammatory potential and quality with offspring birth outcomes: An individual participant data pooled analysis of 7 European cohorts in the ALPHABET consortium

Auteurs: Ling-Wei Chen, Adrien M. Aubert, Nitin Shivappa, Jonathan Y. Bernard, Sara M. Mensink-Bout, Aisling A. Geraghty, John Mehegan, Matthew Suderman, Kinga Polanska, Wojciech Hanke, Elzbieta Trafalska, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Liesbeth Duijts, Barbara Heude, James R. Hébert, Fionnuala M. McAuliffe, Cecily C. Kelleher, Catherine M. Phillips
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Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth

Auteurs: G. S. Monasso, T. Voortman and J. F. Felix
Publié dans: Epigenetics, Numéro 15592294, 2022, ISSN 1559-2294
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Associations of early-life pet ownership with asthma and allergic sensitization: A meta-analysis of more than 77,000 children from the EU Child Cohort Network

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Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts

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Prenatal exposure to organophosphate pesticides and brain morphology and white matter microstructure in preadolescents

Auteurs: Michiel A. van den Dries, Sander Lamballais, Hanan El Marroun, Anjoeka Pronk, Suzanne Spaan, Kelly K. Ferguson, Matthew P. Longnecker, Henning Tiemeier, Mònica Guxens
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Phthalate and Bisphenol Exposure during Pregnancy and Offspring Nonverbal IQ

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Estimated whole-brain and lobe-specific radiofrequency electromagnetic fields doses and brain volumes in preadolescents

Auteurs: Alba Cabré-Riera, Hanan El Marroun, Ryan Muetzel, Luuk van Wel, Ilaria Liorni, Arno Thielens, Laura Ellen Birks, Livia Pierotti, Anke Huss, Wout Joseph, Joe Wiart, Myles Capstick, Manon Hillegers, Roel Vermeulen, Elisabeth Cardis, Martine Vrijheid, Tonya White, Martin Röösli, Henning Tiemeier, Mònica Guxens
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Screening and management options for severe thinness during pregnancy in India

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Early-life respiratory tract infections and the risk of school-age lower lung function and asthma: a meta-analysis of 150 000 European children

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Understanding the cumulative risk of maternal prenatal biopsychosocial factors on birth weight: a DynaHEALTH study on two birth cohorts

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The LifeCycle Project-EU Child Cohort Network: a federated analysis infrastructure and harmonized data of more than 250,000 children and parents

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Dietary Patterns in Early Childhood and the Risk of Childhood Overweight: The GECKO Drenthe Birth Cohort

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The EU Child Cohort Network’s core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables

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Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years

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APOE ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns—Helsinki Birth Cohort Study

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Effect of milk protein content in Toddler formula on later BMI and obesity risk: protocol of the multicentre randomised controlled Toddler Milk Intervention (ToMI) trial

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Tailoring an online breastfeeding course for Southeast Asian paediatric trainees- A qualitative study of user experience from Malaysia and Thailand

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Fetal and Childhood Exposure to Parental Tobacco Smoking and Arterial Health at Age 10 Years

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The determinants and longitudinal changes in vitamin D status in middle-age: a Northern Finland Birth Cohort 1966 study

Auteurs: Helmi Ikonen, Johanna Lumme, Jussi Seppälä, Paula Pesonen, Terhi Piltonen, Marjo-Riitta Järvelin, Karl-Heinz Herzig, Jouko Miettunen, Maarit Niinimäki, Saranya Palaniswamy, Sylvain Sebert, Marja Ojaniemi
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Association of Gestational Age at Birth With Brain Morphometry

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Body Fat Distribution, Overweight, and Cardiac Structures in School‐Age Children: A Population‐Based Cardiac Magnetic Resonance Imaging Study

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Genome-wide DNA methylation patterns associated with general psychopathology in children

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Early-life environmental exposure determinants of child behavior in Europe: A longitudinal, population-based study

Auteurs: Léa Maitre, Jordi Julvez, Monica López-Vicente, Charline Warembourg, Ibon Tamayo-Uria, Claire Philippat, Kristine B. Gützkow, Monica Guxens, Sandra Andrusaityte, Xavier Basagaña, Maribel Casas, Montserrat de Castro, Leda Chatzi, Jorunn Evandt, Juan R. Gonzalez, Regina Gražulevičienė, Line Smastuen Haug, Barbara Heude, Carles Hernandez-Ferrer, Mariza Kampouri, Dan Manson, Sandra Marquez, Ros
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Association of the serum metabolomic profile by nuclear magnetic resonance spectroscopy with sperm parameters: a cross-sectional study of 325 men

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Dynamic prediction of childhood high blood pressure in a population-based birth cohort: a model development study

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In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts

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Frequent Bullying Involvement and Brain Morphology in Children

Auteurs: Ryan L. Muetzel, Rosa H. Mulder, Sander Lamballais, Andrea P. Cortes Hidalgo, Pauline Jansen, Berna Güroğlu, Meike W. Vernooiji, Manon Hillegers, Tonya White, Hanan El Marroun, Henning Tiemeier
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Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Auteurs: Simon Kebede Merid, Alexei Novoloaca, Gemma C. Sharp, Leanne K. Küpers, Alvin T. Kho, Ritu Roy, Lu Gao, Isabella Annesi-Maesano, Pooja Jain, Michelle Plusquin, Manolis Kogevinas, Catherine Allard, Florianne O. Vehmeijer, Nabila Kazmi, Lucas A. Salas, Faisal I. Rezwan, Hongmei Zhang, Sylvain Sebert, Darina Czamara, Sheryl L. Rifas-Shiman, Phillip E. Melton, Debbie A. Lawlor, Göran Pershagen, Carr
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Maternal postnatal depression and offspring depression at age 24 years in a UK-birth cohort: the mediating role of maternal nurturing behaviours concerning feeding, crying and sleeping

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Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics

Auteurs: Joshua A. Bell, Diana L. Santos Ferreira, Abigail Fraser, Ana Luiza G. Soares, Laura D. Howe, Deborah A. Lawlor, David Carslake, George Davey Smith, Linda M. O’Keeffe
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A population-based resource for intergenerational metabolomics analyses in pregnant women and their children: the Generation R Study

Auteurs: Ellis Voerman, Vincent W. V. Jaddoe, Olaf Uhl, Engy Shokry, Jeannie Horak, Janine F. Felix, Berthold Koletzko, Romy Gaillard
Publié dans: Metabolomics, Numéro 16/4, 2020, ISSN 1573-3882
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Developing an integrated microsimulation model for the impact of fiscal policies on child health in Europe: the example of childhood obesity in Italy

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A bit of salt, a trace of life: Gender norms and the impact of a salt iodization program on human capital formation of school aged children

Auteurs: Z. Deng, M. Lindeboom
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A scoping review of nutritional interventions and policy guidelines in the interconception period for prevention of noncommunicable diseases

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Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children's blood

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Maternal and neonatal 25-hydroxyvitamin D concentrations and school-age lung function, asthma and allergy. The Generation R Study.

Auteurs: Sara M. Mensink-Bout; Evelien R. van Meel; Johan C. de Jongste; Trudy Voortman; Irwin K.M. Reiss; Nicolette W. de Jong; Vincent W. V. Jaddoe; Liesbeth Duijts
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Radiofrequency electromagnetic fields from mobile communication: Description of modeled dose in brain regions and the body in European children and adolescents

Auteurs: Laura Ellen Birks, Luuk van Wel, Ilaria Liorni, Livia Pierotti, Mònica Guxens, Anke Huss, Milena Foerster, Myles Capstick, Marloes Eeftens, Hanan El Marroun, Marisa Estarlich, Mara Gallastegi, Llúcia González Safont, Wout Joseph, Loreto Santa-Marina, Arno Thielens, Maties Torrent, Tanja Vrijkotte, Joe Wiart, Martin Röösli, Elisabeth Cardis, Roel Vermeulen, Martine Vrijheid
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Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

Auteurs: Lise G. Bjerregaard, Niko Wasenius, Rozenn Nedelec, Line K. Gjærde, Lars Ängquist, Karl-Heinz Herzig, Gorm B. Jensen, Erik L. Mortensen, Merete Osler, Kim Overvad, Tea Skaaby, Anne Tjønneland, Thorkild I.A. Sørensen, Marjo-Riitta Järvelin, Johan G. Eriksson, Sylvain Sebert, Jennifer L. Baker
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Risk Factors For Hearing Decline From Childhood To Early Adolescence

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Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register

Auteurs: Alina Rodriguez, Yingbo Wang, Anohki Ali Khan, Rufus Cartwright, Mika Gissler, Marjo-Riitta Järvelin
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Prenatal Exposure to Nonpersistent Chemical Mixtures and Fetal Growth: A Population-Based Study

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Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

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Machine Learning-Based DNA Methylation Score for Fetal Exposure to Maternal Smoking: Development and Validation in Samples Collected from Adolescents and Adults

Auteurs: Sebastian Rauschert, Phillip E. Melton, Anni Heiskala, Ville Karhunen, Graham Burdge, Jeffrey M. Craig, Keith M. Godfrey, Karen Lillycrop, Trevor A. Mori, Lawrence J. Beilin, Wendy H. Oddy, Craig Pennell, Marjo-Riitta Järvelin, Sylvain Sebert, Rae-Chi Huang
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Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

Auteurs: Sara Sammallahti, Andrea P. Cortes Hidalgo, Samuli Tuominen, Anni Malmberg, Rosa H. Mulder, Kelly J. Brunst, Silvia Alemany, Nancy S. McBride, Paul Yousefi, Jonathan A. Heiss, Nia McRae, Christian M. Page, Jianping Jin, Giancarlo Pesce, Doretta Caramaschi, Sheryl L. Rifas-Shiman, Nastassja Koen, Charleen D. Adams, Maria C. Magnus, Nour Baïz, Andrew Ratanatharathorn, Darina Czamara, Siri E. Håber
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Combining Longitudinal Data From Different Cohorts to Examine the Life-Course Trajectory

Auteurs: Rachael A Hughes, Kate Tilling, Deborah A Lawlor
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Ethnic differences in adverse iron status in early pregnancy: a cross-sectional population-based study

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Parental psychological distress during pregnancy and the risk of childhood lower lung function and asthma: a population-based prospective cohort study

Auteurs: Evelien R van Meel, Gautam Saharan, Vincent WV Jaddoe, Johan C de Jongste, Irwin KM Reiss, Henning Tiemeier, Hanan El Marroun, Liesbeth Duijts
Publié dans: Thorax, Numéro 75/12, 2020, Page(s) 1074-1081, ISSN 0040-6376
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ERS International Congress 2020: highlights from the Paediatric Assembly

Auteurs: Cristina Ardura-Garcia, Sara Cuevas-Ocaña, Nadine Freitag, Asterios Kampouras, John A. King, Panayiotis Kouis, Sara M. Mensink-Bout, Abigail L. Whitehouse, Emma Williams, Theodore Dassios, Liesbeth Duijts, Refika H Ersu, Erol A. Gaillard, Alex R. Horsley, Marijke Proesmans, Robbert Rottier, Dirk Schramm, Alexander Moeller, Marielle W. Pijnenburg
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Timing- and Dose-Specific Associations of Prenatal Smoke Exposure With Newborn DNA Methylation

Auteurs: Giulietta S Monasso, Vincent W V Jaddoe, Johan C de Jongste, Liesbeth Duijts, Janine F Felix
Publié dans: Nicotine & Tobacco Research, Numéro 22/10, 2020, Page(s) 1917-1922, ISSN 1469-994X
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DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

Auteurs: Jenny van Dongen, Fiona A. Hagenbeek, Matthew Suderman, Peter J. Roetman, Karen Sugden, Andreas G. Chiocchetti, Khadeeja Ismail, Rosa H. Mulder, Jonathan D. Hafferty, Mark J. Adams, Rosie M. Walker, Stewart W. Morris, Jari Lahti, Leanne K. Küpers, Georgia Escaramis, Silvia Alemany, Marc Jan Bonder, Mandy Meijer, Hill F. Ip, Rick Jansen, Bart M. L. Baselmans, Priyanka Parmar, Estelle Lowry, Fabian
Publié dans: Molecular Psychiatry, 2021, ISSN 1359-4184
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Early exposure to social disadvantages and later life body mass index beyond genetic predisposition in three generations of Finnish birth cohorts

Auteurs: Estelle Lowry, Nina Rautio, Niko Wasenius, Tom A. Bond, Jari Lahti, Ioanna Tzoulaki, Abbas Dehghan, Anni Heiskala, Leena Ala-Mursula, Jouko Miettunen, Johan Eriksson, Marjo-Riitta Järvelin, Sylvain Sebert
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Eczema phenotypes and risk of allergic and respiratory conditions in school age children

Auteurs: Chen Hu, Tamar Nijsten, Evelien R. van Meel, Nicole S. Erler, Christophe Piketty, Nicolette W. de Jong, Suzanne G. M. A. Pasmans, Johan C. de Jongste, Liesbeth Duijts
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Associations of Th2, Th17, Treg cells, and IgA + memory B cells with atopic disease in children: The Generation R Study

Auteurs: Kirsten I. M. Looman, Evelien R. Meel, Christina Grosserichter‐Wagener, Floor J. M. Vissers, Janice H. Klingenberg, Nicolette W. Jong, Johan C. Jongste, Suzanne G. M. A. Pasmans, Liesbeth Duijts, Menno C. Zelm, Henriëtte A. Moll
Publié dans: Allergy, Numéro 75/1, 2020, Page(s) 178-187, ISSN 0105-4538
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/all.14010

The early-life exposome and epigenetic age acceleration in children

Auteurs: Paula de Prado-Bert, Carlos Ruiz-Arenas, Marta Vives-Usano, Sandra Andrusaityte, Solène Cadiou, Ángel Carracedo, Maribel Casas, Leda Chatzi, Payam Dadvand, Juan R. González, Regina Grazuleviciene, Kristine B. Gutzkow, Line S. Haug, Carles Hernandez-Ferrer, Hector C. Keun, Johanna Lepeule, Léa Maitre, Rosie McEachan, Mark J. Nieuwenhuijsen, Dolors Pelegrí, Oliver Robinson, Rémy Slama, Marina
Publié dans: Environment International, Numéro 155, 2021, Page(s) 106683, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
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Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies

Auteurs: E. W. Tobi, D. L. Juvinao-Quintero, J. Ronkainen, R. Ott, R. Alfano, M. Canouil, et al.
Publié dans: Diabetes Care, Numéro 01495992, 2022, ISSN 0149-5992
Éditeur: American Diabetes Association
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Maternal hemoglobin associates with preterm delivery and small for gestational age in two Finnish birth cohorts

Auteurs: Justiina Ronkainen, Estelle Lowry, Anni Heiskala, Iida Uusitalo, Peppi Koivunen, Eero Kajantie, Marja Vääräsmäki, Marjo-Riitta Järvelin, Sylvain Sebert
Publié dans: European Journal of Obstetrics & Gynecology and Reproductive Biology, Numéro 238, 2019, Page(s) 44-48, ISSN 0301-2115
Éditeur: Elsevier BV
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Metabolomic Signatures in Pediatric Crohn’s Disease Patients with Mild or Quiescent Disease Treated with Partial Enteral Nutrition: A Feasibility Study

Auteurs: Jair Gonzalez Marques, Engy Shokry, Klara Frivolt, Katharina Julia Werkstetter, Annecarin Brückner, Tobias Schwerd, Sibylle Koletzko, Berthold Koletzko
Publié dans: SLAS TECHNOLOGY: Translating Life Sciences Innovation, Numéro 26/2, 2021, Page(s) 165-177, ISSN 2472-6303
Éditeur: SAGE Choice
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Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age

Auteurs: Giulietta S Monasso, Susana Santos, Madelon L Geurtsen, Sandra G Heil, Janine F Felix, Vincent W V Jaddoe
Publié dans: The Journal of Nutrition, Numéro 151/6, 2021, Page(s) 1628-1636, ISSN 0022-3166
Éditeur: American Society for Nutritional Sciences
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Availability, use of, and satisfaction with green space, and children's mental wellbeing at age 4 years in a multicultural, deprived, urban area: results from the Born in Bradford cohort study

Auteurs: Rosemary R C McEachan, Tiffany C Yang, Hannah Roberts, Kate E Pickett, Diana Arseneau-Powell, Christopher J Gidlow, John Wright, Mark Nieuwenhuijsen
Publié dans: The Lancet Planetary Health, Numéro 2/6, 2018, Page(s) e244-e254, ISSN 2542-5196
Éditeur: Elsevier
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Increased correlation between methylation sites in epigenome-wide replication studies: impact on analysis and results

Auteurs: Maja Popovic, Francesca Fasanelli, Valentina Fiano, Annibale Biggeri, Lorenzo Richiardi
Publié dans: Epigenomics, Numéro 9/12, 2017, Page(s) 1489-1502, ISSN 1750-1911
Éditeur: Future Medicine Ltd.
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Effects decomposition in mediation analysis: a numerical example

Auteurs: Zugna D, Richiardi L
Publié dans: Epidemiologia & Prevenzione, Numéro 42-2, 2018, Page(s) 127-133, ISSN 1120-9763
Éditeur: Zadig srl
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Maternal psychological distress during pregnancy and childhood health outcomes: a narrative review

Auteurs: F. O. L. Vehmeijer, M. Guxens, L. Duijts, H. El Marroun
Publié dans: Journal of Developmental Origins of Health and Disease, Numéro 10/3, 2019, Page(s) 274-285, ISSN 2040-1744
Éditeur: Cambridge University Press
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Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts

Auteurs: Zuelma A. Contreras, Zhanghua Chen, Theano Roumeliotaki, Isabella Annesi-Maesano, Nour Baïz, Andrea von Berg, Anna Bergström, Sarah Crozier, Liesbeth Duijts, Sandra Ekström, Esben Eller, Maria P. Fantini, Henrik Fomsgaard Kjaer, Francesco Forastiere, Beatrix Gerhard, Davide Gori, Margreet W. Harskamp-van Ginkel, Joachim Heinrich, Carmen Iñiguez, Hazel Inskip, Thomas Keil, Manolis Kogevinas, S
Publié dans: European Respiratory Journal, Numéro 52/3, 2018, Page(s) 1800504, ISSN 0903-1936
Éditeur: European Respiratory Society
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Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn

Auteurs: Emilie M. Herzog, Alex J. Eggink, Sten P. Willemsen, Roderick C. Slieker, Kim P.J. Wijnands, Janine F. Felix, Jun Chen, Andrew Stubbs, Peter J. van der Spek, Joyce B. van Meurs, Régine P.M. Steegers-Theunissen
Publié dans: Placenta, Numéro 58, 2017, Page(s) 122-132, ISSN 0143-4004
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Population DNA methylation studies in the Developmental Origins of Health and Disease (DOHaD) framework

Auteurs: J. F. Felix, C. A. M. Cecil
Publié dans: Journal of Developmental Origins of Health and Disease, 2018, Page(s) 1-8, ISSN 2040-1744
Éditeur: Cambridge University Press
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The effect of early growth patterns and lung function on the development of childhood asthma: a population based study

Auteurs: Maribel Casas, Herman T den Dekker, Claudia J Kruithof, Irwin K Reiss, Martine Vrijheid, Jordi Sunyer, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
Publié dans: Thorax, 2018, Page(s) thoraxjnl-2017-211216, ISSN 0040-6376
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Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Auteurs: Janine F Felix, Bonnie R Joubert, Andrea A Baccarelli, Gemma C Sharp, Catarina Almqvist, Isabella Annesi-Maesano, Hasan Arshad, Nour Baïz, Marian J Bakermans-Kranenburg, Kelly M Bakulski, Elisabeth B Binder, Luigi Bouchard, Carrie V Breton, Bert Brunekreef, Kelly J Brunst, Esteban G Burchard, Mariona Bustamante, Leda Chatzi, Monica Cheng Munthe-Kaas, Eva Corpeleijn, Darina Czamara, Dana Dabelea,
Publié dans: International Journal of Epidemiology, Numéro 47/1, 2017, Page(s) 22-23u, ISSN 0300-5771
Éditeur: Oxford University Press
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Premature birth and circadian preference in young adulthood: evidence from two birth cohorts

Auteurs: Johan Björkqvist, Anu-Katriina Pesonen, Liisa Kuula, Hanna-Maria Matinolli, Aulikki Lano, Marika Sipola-Leppänen, Marjaana Tikanmäki, Dieter Wolke, Marjo-Riitta Järvelin, Johan G Eriksson, Sture Andersson, Marja Vääräsmäki, Kati Heinonen, Katri Räikkönen, Petteri Hovi, Eero Kajantie
Publié dans: Chronobiology International, Numéro 35/4, 2018, Page(s) 555-564, ISSN 0742-0528
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Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study

Auteurs: Rebecca C. Richmond, Nicholas J. Timpson, Janine F. Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W. Jaddoe, Debbie A. Lawlor
Publié dans: PLOS Medicine, Numéro 14/1, 2017, Page(s) e1002221, ISSN 1549-1277
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The role of respiratory tract infections and the microbiome in the development of asthma: A narrative review

Auteurs: Evelien R. van Meel, Vincent W. V. Jaddoe, Klaus Bønnelykke, Johan C. de Jongste, Liesbeth Duijts
Publié dans: Pediatric Pulmonology, Numéro 52/10, 2017, Page(s) 1363-1370, ISSN 8755-6863
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Sources of confounding in life course epidemiology

Auteurs: S. Santos, D. Zugna, C. Pizzi, L. Richiardi
Publié dans: Journal of Developmental Origins of Health and Disease, 2018, Page(s) 1-7, ISSN 2040-1744
Éditeur: Cambridge University Press
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Exposure to elemental composition of outdoor PM 2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts

Auteurs: Małgorzata J. Lubczyńska, Jordi Sunyer, Henning Tiemeier, Daniela Porta, Monika Kasper-Sonnenberg, Vincent W.V. Jaddoe, Xavier Basagaña, Albert Dalmau-Bueno, Francesco Forastiere, Jürgen Wittsiepe, Barbara Hoffmann, Mark Nieuwenhuijsen, Gerard Hoek, Kees de Hoogh, Bert Brunekreef, Mònica Guxens
Publié dans: Environment International, Numéro 109, 2017, Page(s) 170-180, ISSN 0160-4120
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Fetal and Infant Growth Patterns and Risk of Lower Lung Function and Asthma. The Generation R Study

Auteurs: Herman T. den Dekker, Vincent W. V. Jaddoe, Irwin K. Reiss, Johan C. de Jongste, Liesbeth Duijts
Publié dans: American Journal of Respiratory and Critical Care Medicine, Numéro 197/2, 2018, Page(s) 183-192, ISSN 1073-449X
Éditeur: American Thoracic Society
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Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study

Auteurs: Maria C Magnus, Kozeta Miliku, Anna Bauer, Stephanie M Engel, Janine F Felix, Vincent W V Jaddoe, Debbie A Lawlor, Stephanie J London, Per Magnus, Ralph McGinnis, Wenche Nystad, Christian M Page, Fernando Rivadeneira, Lars C Stene, German Tapia, Nicholas Williams, Carolina Bonilla, Abigail Fraser
Publié dans: BMJ, 2018, Page(s) k2167, ISSN 0959-8138
Éditeur: British Medical Association
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Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts

Auteurs: Gemma C Sharp, Ryan Arathimos, Sarah E Reese, Christian M Page, Janine Felix, Leanne K Küpers, Sheryl L Rifas-Shiman, Chunyu Liu, Kimberley Burrows, Shanshan Zhao, Maria C Magnus, Liesbeth Duijts, Eva Corpeleijn, Dawn L DeMeo, Augusto Litonjua, Andrea Baccarelli, Marie-France Hivert, Emily Oken, Harold Snieder, Vincent Jaddoe, Wenche Nystad, Stephanie J London, Caroline L Relton, Luisa Zuccolo
Publié dans: Epigenomics, Numéro 10/1, 2018, Page(s) 27-42, ISSN 1750-1911
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Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Auteurs: Robin N Beaumont, Nicole M Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C Richmond, Lavinia Paternoster, Jonathan P Bradfield, Eskil Kreiner-Møller, Ville Huikari, Sarah Metrustry, Kathryn L Lunetta, Jodie N Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J Barton, Ana Espinosa, Julie A Marsh, Catherine Potter, Ge Zhang
Publié dans: Human Molecular Genetics, Numéro 27/4, 2018, Page(s) 742-756, ISSN 0964-6906
Éditeur: Oxford University Press
DOI: 10.1093/hmg/ddx429

A population-based prospective cohort study examining the influence of early-life respiratory tract infections on school-age lung function and asthma

Auteurs: Evelien R van Meel, Herman T den Dekker, Niels J Elbert, Pauline W Jansen, Henriëtte A Moll, Irwin K Reiss, Johan C de Jongste, Vincent W V Jaddoe, Liesbeth Duijts
Publié dans: Thorax, Numéro 73/2, 2018, Page(s) 167-173, ISSN 0040-6376
Éditeur: BMJ Publishing Group
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Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Auteurs: Johannes Waage, Marie Standl, John A. Curtin, Leon E. Jessen, Jonathan Thorsen, Chao Tian, Nathan Schoettler, Carlos Flores, Abdel Abdellaoui, Tarunveer S. Ahluwalia, Alexessander C. Alves, Andre F. S. Amaral, Josep M. Antó, Andreas Arnold, Amalia Barreto-Luis, Hansjörg Baurecht, Catharina E. M. van Beijsterveldt, Eugene R. Bleecker, Sílvia Bonàs-Guarch, Dorret I. Boomsma, Susanne Brix, Supind
Publié dans: Nature Genetics, Numéro 50/8, 2018, Page(s) 1072-1080, ISSN 1061-4036
Éditeur: Nature Publishing Group
DOI: 10.1038/s41588-018-0157-1

Air Pollution Exposure During Fetal Life, Brain Morphology, and Cognitive Function in School-Age Children

Auteurs: Mònica Guxens, Małgorzata J. Lubczyńska, Ryan L. Muetzel, Albert Dalmau-Bueno, Vincent W.V. Jaddoe, Gerard Hoek, Aad van der Lugt, Frank C. Verhulst, Tonya White, Bert Brunekreef, Henning Tiemeier, Hanan El Marroun
Publié dans: Biological Psychiatry, Numéro 84/4, 2018, Page(s) 295-303, ISSN 0006-3223
Éditeur: Elsevier BV
DOI: 10.1016/j.biopsych.2018.01.016

Maternal and fetal genetic contribution to gestational weight gain

Auteurs: N M Warrington, R Richmond, B Fenstra, R Myhre, R Gaillard, L Paternoster, C A Wang, R N Beaumont, S Das, M Murcia, S J Barton, A Espinosa, E Thiering, M Atalay, N Pitkänen, I Ntalla, A E Jonsson, R Freathy, V Karhunen, C M T Tiesler, C Allard, A Crawford, S M Ring, M Melbye, P Magnus, F Rivadeneira, L Skotte, T Hansen, J Marsh, M Guxens, J W Holloway, H Grallert, V W V Jaddoe, W L Lowe Jr, T Rou
Publié dans: International Journal of Obesity, Numéro 42/4, 2017, Page(s) 775-784, ISSN 0307-0565
Éditeur: Nature Publishing Group
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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Auteurs: Florence Demenais, Patricia Margaritte-Jeannin, Kathleen C. Barnes, William O. C. Cookson, Janine Altmüller, Wei Ang, R. Graham Barr, Terri H. Beaty, Allan B. Becker, John Beilby, Hans Bisgaard, Unnur Steina Bjornsdottir, Eugene Bleecker, Klaus Bønnelykke, Dorret I. Boomsma, Emmanuelle Bouzigon, Christopher E. Brightling, Myriam Brossard, Guy G. Brusselle, Esteban Burchard, Kristin M. Burkart, A
Publié dans: Nature Genetics, Numéro 50/1, 2018, Page(s) 42-53, ISSN 1061-4036
Éditeur: Nature Publishing Group
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Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

Auteurs: Gemma C Sharp, Lucas A Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W Holloway, Akram Ghantous, Simon K Merid, Kelly M Bakulski, Leanne K Küpers, Hongmei Zhang, Rebecca C Richmond, Christian M Page, Liesbeth Duijts, Rolv T Lie, Phillip E Melton, J
Publié dans: Human Molecular Genetics, Numéro 26/20, 2017, Page(s) 4067-4085, ISSN 0964-6906
Éditeur: Oxford University Press
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Baseline selection on a collider: a ubiquitous mechanism occurring in both representative and selected cohort studies

Auteurs: Lorenzo Richiardi, Neil Pearce, Eva Pagano, Daniela Di Cuonzo, Daniela Zugna, Costanza Pizzi
Publié dans: Journal of Epidemiology and Community Health, Numéro 73/5, 2019, Page(s) 475-480, ISSN 0143-005X
Éditeur: British Medical Association
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Narrative review of reviews of preconception interventions to prevent an increased risk of obesity and non‐communicable diseases in children

Auteurs: Chandni Maria Jacob, Marie‐Louise Newell, Mark Hanson
Publié dans: Obesity Reviews, Numéro 20/S1, 2019, Page(s) 5-17, ISSN 1467-7881
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Do the concepts of “life course approach” and “developmental origins of health and disease” underpin current maternity care? Study protocol

Auteurs: Chandni Maria Jacob, Wendy T. Lawrence, Hazel M. Inskip, Fionnuala M. McAuliffe, Sarah Louise Killeen, Mark Hanson
Publié dans: International Journal of Gynecology & Obstetrics, Numéro 147/2, 2019, Page(s) 140-146, ISSN 0020-7292
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Research question and study validity

Auteurs: Richiardi L
Publié dans: Epidemiologia e prevenzione, Numéro 43/4, 2019, Page(s) 217-219, ISSN 1120-9763
Éditeur: Zadig srl
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Differentially methylated DNA regions in early childhood wheezing: An epigenome‐wide study using saliva

Auteurs: Maja Popovic, Valentina Fiano, Francesca Fasanelli, Morena Trevisan, Chiara Grasso, Manuela Bianca Assumma, Anna Gillio‐Tos, Silvia Polidoro, Laura De Marco, Franca Rusconi, Franco Merletti, Daniela Zugna, Lorenzo Richiardi
Publié dans: Pediatric Allergy and Immunology, Numéro 30/3, 2019, Page(s) 305-314, ISSN 0905-6157
Éditeur: Blackwell Publishing Inc.
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Infant breastfeeding and childhood general, visceral, liver, and pericardial fat measures assessed by magnetic resonance imaging

Auteurs: Suzanne Vogelezang, Susana Santos, Eline M van der Beek, Marieke Abrahamse-Berkeveld, Liesbeth Duijts, Aad van der Lugt, Janine F Felix, Vincent W V Jaddoe
Publié dans: The American Journal of Clinical Nutrition, Numéro 108/4, 2018, Page(s) 722-729, ISSN 0002-9165
Éditeur: American Society for Clinical Nutrition, Inc.
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Exposure to Maternal Depressive Symptoms in Fetal Life or Childhood and Offspring Brain Development: A Population-Based Imaging Study

Auteurs: Runyu Zou, Henning Tiemeier, Jan van der Ende, Frank C. Verhulst, Ryan L. Muetzel, Tonya White, Manon Hillegers, Hanan El Marroun
Publié dans: American Journal of Psychiatry, Numéro 176/9, 2019, Page(s) 702-710, ISSN 0002-953X
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Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort

Auteurs: Judith S. Brand, Jane West, Derek Tuffnell, Philippa K. Bird, John Wright, Kate Tilling, Debbie A. Lawlor
Publié dans: BMC Medicine, Numéro 16/1, 2018, ISSN 1741-7015
Éditeur: BioMed Central
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The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial

Auteurs: Harriet L. Mills, Nashita Patel, Sara L. White, Dharmintra Pasupathy, Annette L. Briley, Diana L. Santos Ferreira, Paul T. Seed, Scott M. Nelson, Naveed Sattar, Kate Tilling, Lucilla Poston, Deborah A. Lawlor
Publié dans: BMC Medicine, Numéro 17/1, 2019, ISSN 1741-7015
Éditeur: BioMed Central
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Epigenome-wide association study of seizures in childhood and adolescence

Auteurs: Doretta Caramaschi, Charlie Hatcher, Rosa H. Mulder, Janine F. Felix, Charlotte A. M. Cecil, Caroline L. Relton, Esther Walton
Publié dans: Clinical Epigenetics, Numéro 12/1, 2020, ISSN 1868-7075
Éditeur: Springer Verlag
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Income inequality and social gradients in children’s height: a comparison of cohort studies from five high-income countries

Auteurs: Philippa K Bird, Kate E Pickett, Hilary Graham, Tomas Faresjö, Vincent W V Jaddoe, Johnny Ludvigsson, Hein Raat, Louise Seguin, Anne I Wijtzes, Jennifer J McGrath
Publié dans: BMJ Paediatrics Open, Numéro 3/1, 2019, Page(s) e000568, ISSN 2399-9772
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Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

Auteurs: Susana Santos, Iris Eekhout, Ellis Voerman, Romy Gaillard, Henrique Barros, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Luigi Gagliardi, Vagelis Georgiu, Keith M. Godfrey, Davide Gori, Veit Grote, Wojciech Hanke, Irva Hertz-Picciotto, Barb
Publié dans: BMC Medicine, Numéro 16/1, 2018, ISSN 1741-7015
Éditeur: BioMed Central
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Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood

Auteurs: Andres Cardenas, Sabrina Faleschini, Andrea Cortes Hidalgo, Sheryl L. Rifas-Shiman, Andrea A. Baccarelli, Dawn L. DeMeo, Augusto A. Litonjua, Alexander Neumann, Janine F. Felix, Vincent W. V. Jaddoe, Hanan El Marroun, Henning Tiemeier, Emily Oken, Marie-France Hivert, Heather H. Burris
Publié dans: Clinical Epigenetics, Numéro 11/1, 2019, ISSN 1868-7075
Éditeur: Springer Verlag
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Observed infant-parent attachment and brain morphology in middle childhood– A population-based study

Auteurs: Andrea P. Cortes Hidalgo, Ryan Muetzel, Maartje P.C.M. Luijk, Marian J. Bakermans-Kranenburg, Hanan El Marroun, Meike W. Vernooij, Marinus H. van IJzendoorn, Tonya White, Henning Tiemeier
Publié dans: Developmental Cognitive Neuroscience, Numéro 40, 2019, Page(s) 100724, ISSN 1878-9293
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DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

Auteurs: Petri Wiklund, Ville Karhunen, Rebecca C. Richmond, Priyanka Parmar, Alina Rodriguez, Maneka De Silva, Matthias Wielscher, Faisal I. Rezwan, Tom G. Richardson, Juha Veijola, Karl-Heinz Herzig, John W. Holloway, Caroline L. Relton, Sylvain Sebert, Marjo-Riitta Järvelin
Publié dans: Clinical Epigenetics, Numéro 11/1, 2019, ISSN 1868-7075
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Newborn and childhood differential DNA methylation and liver fat in school-age children

Auteurs: Madelon L. Geurtsen, Vincent W. V. Jaddoe, Lucas A. Salas, Susana Santos, Janine F. Felix
Publié dans: Clinical Epigenetics, Numéro 12/1, 2020, ISSN 1868-7075
Éditeur: Springer Verlag
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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Auteurs: Priyanka Parmar, Estelle Lowry, Giovanni Cugliari, Matthew Suderman, Rory Wilson, Ville Karhunen, Toby Andrew, Petri Wiklund, Matthias Wielscher, Simonetta Guarrera, Alexander Teumer, Benjamin Lehne, Lili Milani, Niek de Klein, Pashupati P. Mishra, Phillip E. Melton, Pooja R. Mandaviya, Silva Kasela, Jana Nano, Weihua Zhang, Yan Zhang, Andre G. Uitterlinden, Annette Peters, Ben Schöttker, Christi
Publié dans: EBioMedicine, Numéro 38, 2018, Page(s) 206-216, ISSN 2352-3964
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Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis

Auteurs: Olena Gruzieva, Cheng-Jian Xu, Paul Yousefi, Caroline Relton, Simon Kebede Merid, Carrie V. Breton, Lu Gao, Heather E. Volk, Jason I. Feinberg, Christine Ladd-Acosta, Kelly Bakulski, Charles Auffray, Nathanaël Lemonnier, Michelle Plusquin, Akram Ghantous, Zdenko Herceg, Tim S. Nawrot, Costanza Pizzi, Lorenzo Richiardi, Franca Rusconi, Paolo Vineis, Manolis Kogevinas, Janine F. Felix, Liesbeth Dui
Publié dans: Environmental Health Perspectives, Numéro 127/5, 2019, Page(s) 057012, ISSN 0091-6765
Éditeur: US Department of Health and Human Services
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Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

Auteurs: Sinjini Sikdar, Roby Joehanes, Bonnie R Joubert, Cheng-Jian Xu, Marta Vives-Usano, Faisal I Rezwan, Janine F Felix, James M Ward, Weihua Guan, Rebecca C Richmond, Jennifer A Brody, Leanne K Küpers, Nour Baïz, Siri E Håberg, Jennifer A Smith, Sarah E Reese, Stella Aslibekyan, Cathrine Hoyo, Radhika Dhingra, Christina A Markunas, Tao Xu, Lindsay M Reynolds, Allan C Just, Pooja R Mandaviya, Akram
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Exposure to Air Pollution during Pregnancy and Childhood, and White Matter Microstructure in Preadolescents

Auteurs: Małgorzata J. Lubczyńska, Ryan L. Muetzel, Hanan El Marroun, Xavier Basagaña, Maciej Strak, William Denault, Vincent W.V. Jaddoe, Manon Hillegers, Meike W. Vernooij, Gerard Hoek, Tonya White, Bert Brunekreef, Henning Tiemeier, Mònica Guxens
Publié dans: Environmental Health Perspectives, Numéro 128/2, 2020, Page(s) 027005, ISSN 0091-6765
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Epigenomics of being bullied: changes in DNA methylation following bullying exposure

Auteurs: Rosa H. Mulder, Esther Walton, Alexander Neumann, Lotte C. Houtepen, Janine F. Felix, Marian J. Bakermans-Kranenburg, Matthew Suderman, Henning Tiemeier, Marinus H. van IJzendoorn, Caroline L. Relton, Charlotte A. M. Cecil
Publié dans: Epigenetics, 2020, Page(s) 1-15, ISSN 1559-2294
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Residential Proximity to Major Roadways at Birth, DNA Methylation at Birth and Midchildhood, and Childhood Cognitive Test Scores: Project Viva(Massachusetts, USA)

Auteurs: Cheng Peng, Martijn den Dekker, Andres Cardenas, Sheryl L. Rifas-Shiman, Heike Gibson, Golareh Agha, Maria H. Harris, Brent A. Coull, Joel Schwartz, Augusto A. Litonjua, Dawn L. DeMeo, Marie-France Hivert, Matthew W. Gilman, Sharon K. Sagiv, Yvonne de Kluizenaar, Janine F. Felix, Vincent W. Jaddoe, Emily Oken, Liesbeth Duijts, Diane R. Gold, Andrea A. Baccarelli
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Éditeur: US Department of Health and Human Services
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Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

Auteurs: Herman T. den Dekker, Kimberley Burrows, Janine F. Felix, Lucas A. Salas, Ivana Nedeljkovic, Jin Yao, Sheryl L. Rifas-Shiman, Carlos Ruiz-Arenas, N. Amin, Mariona Bustamante, Dawn L. DeMeo, A. John Henderson, Caitlin G. Howe, Marie-France Hivert, M. Arfan Ikram, Johan C. de Jongste, Lies Lahousse, Pooja R. Mandaviya, Joyce B. van Meurs, Mariona Pinart, Gemma C. Sharp, Lisette Stolk, André G. U
Publié dans: European Respiratory Journal, Numéro 53/4, 2019, Page(s) 1801795, ISSN 0903-1936
Éditeur: European Respiratory Society
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A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

Auteurs: Jonathan P Bradfield, Suzanne Vogelezang, Janine F Felix, Alessandra Chesi, Øyvind Helgeland, Momoko Horikoshi, Ville Karhunen, Estelle Lowry, Diana L Cousminer, Tarunveer S Ahluwalia, Elisabeth Thiering, Eileen Tai-Hui Boh, Mohammad H Zafarmand, Natalia Vilor-Tejedor, Carol A Wang, Raimo Joro, Zhanghua Chen, William J Gauderman, Niina Pitkänen, Esteban J Parra, Lindsay Fernandez-Rhodes, Akram A
Publié dans: Human Molecular Genetics, Numéro 28/19, 2019, Page(s) 3327-3338, ISSN 0964-6906
Éditeur: Oxford University Press
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Epigenome-wide meta-analysis of DNA methylation and childhood asthma

Auteurs: Sarah E. Reese, Cheng-Jian Xu, Herman T. den Dekker, Mi Kyeong Lee, Sinjini Sikdar, Carlos Ruiz-Arenas, Simon K. Merid, Faisal I. Rezwan, Christian M. Page, Vilhelmina Ullemar, Phillip E. Melton, Sam S. Oh, Ivana V. Yang, Kimberley Burrows, Cilla Söderhäll, Dereje D. Jima, Lu Gao, Ryan Arathimos, Leanne K. Küpers, Matthias Wielscher, Peter Rzehak, Jari Lahti, Catherine Laprise, Anne-Marie Mador
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Maternal body mass index, gestational weight gain, and childhood abdominal, pericardial, and liver fat assessed by magnetic resonance imaging

Auteurs: Susana Santos, Claire Monnereau, Janine F. Felix, Liesbeth Duijts, Romy Gaillard, Vincent W. V. Jaddoe
Publié dans: International Journal of Obesity, Numéro 43/3, 2019, Page(s) 581-593, ISSN 0307-0565
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Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

Auteurs: Liang-Dar Hwang, Deborah A Lawlor, Rachel M Freathy, David M Evans, Nicole M Warrington
Publié dans: International Journal of Epidemiology, Numéro 48/5, 2019, Page(s) 1457-1467, ISSN 0300-5771
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Maternal prepregnancy body mass index and offspring white matter microstructure: results from three birth cohorts

Auteurs: Juan Verdejo-Román, Lassi Björnholm, Ryan L. Muetzel, Francisco José Torres-Espínola, Johannes Lieslehto, Vincent Jaddoe, Daniel Campos, Juha Veijola, Tonya White, Andrés Catena, Juha Nikkinen, Vesa Kiviniemi, Marjo-Riitta Järvelin, Henning Tiemeier, Cristina Campoy, Sylvain Sebert, Hanan El Marroun
Publié dans: International Journal of Obesity, Numéro 43/10, 2019, Page(s) 1995-2006, ISSN 0307-0565
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Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts

Auteurs: Tom A Bond, Ville Karhunen, Matthias Wielscher, Juha Auvinen, Minna Männikkö, Sirkka Keinänen-Kiukaanniemi, Marc J Gunter, Janine F Felix, Inga Prokopenko, Jian Yang, Peter M Visscher, David M Evans, Sylvain Sebert, Alex Lewin, Paul F O’Reilly, Debbie A Lawlor, Marjo-Riitta Jarvelin
Publié dans: International Journal of Epidemiology, 2019, ISSN 0300-5771
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A Cross‐Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children

Auteurs: Markus Juonala, Susan Ellul, Debbie A. Lawlor, Diana L. Santos Ferreira, John B. Carlin, Michael Cheung, Terence Dwyer, Melissa Wake, Richard Saffery, David P. Burgner
Publié dans: Journal of the American Heart Association, Numéro 8/14, 2019, ISSN 2047-9980
Éditeur: Wiley-Blackwell
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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Auteurs: Leanne K. Küpers, Claire Monnereau, Gemma C. Sharp, Paul Yousefi, Lucas A. Salas, Akram Ghantous, Christian M. Page, Sarah E. Reese, Allen J. Wilcox, Darina Czamara, Anne P. Starling, Alexei Novoloaca, Samantha Lent, Ritu Roy, Cathrine Hoyo, Carrie V. Breton, Catherine Allard, Allan C. Just, Kelly M. Bakulski, John W. Holloway, Todd M. Everson, Cheng-Jian Xu, Rae-Chi Huang, Diana A. van der Plaat
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
Éditeur: Nature Publishing Group
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Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes

Auteurs: Ellis Voerman, Susana Santos, Hazel Inskip, Pilar Amiano, Henrique Barros, Marie-Aline Charles, Leda Chatzi, George P. Chrousos, Eva Corpeleijn, Sarah Crozier, Myriam Doyon, Merete Eggesbø, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Davide Gori, Wojciech Hanke, Irva Hertz-Picciotto, Barbara Heude, Marie-France Hivert, Daniel Hryhorczuk, Carmen Iñiguez, Anne M. Karvone
Publié dans: JAMA, Numéro 321/17, 2019, Page(s) 1702, ISSN 0098-7484
Éditeur: American Medical Association
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Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

Auteurs: Simon Haworth, Chin Yang Shapland, Caroline Hayward, Bram P. Prins, Janine F. Felix, Carolina Medina-Gomez, Fernando Rivadeneira, Carol Wang, Tarunveer S. Ahluwalia, Martine Vrijheid, Mònica Guxens, Jordi Sunyer, Ioanna Tachmazidou, Klaudia Walter, Valentina Iotchkova, Andrew Jackson, Louise Cleal, Jennifer Huffmann, Josine L. Min, Lærke Sass, Paul R. H. J. Timmers, George Davey Smith, Simon E.
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
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DOI: 10.1038/s41467-018-07863-x

Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis

Auteurs: Bernadeta Patro Golab, Susana Santos, Ellis Voerman, Debbie A Lawlor, Vincent W V Jaddoe, Romy Gaillard, Bernadeta Patro Golab, Susana Santos, Ellis Voerman, Henrique Barros, Anna Bergström, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Graham Devereux, Merete Eggesbø, Sandra Ekström, Maria P Fantini, Sara Farchi, Francesc
Publié dans: The Lancet Child & Adolescent Health, Numéro 2/11, 2018, Page(s) 812-821, ISSN 2352-4642
Éditeur: Elsevier
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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Auteurs: Alexander Teumer, Yong Li, Sahar Ghasemi, Bram P. Prins, Matthias Wuttke, Tobias Hermle, Ayush Giri, Karsten B. Sieber, Chengxiang Qiu, Holger Kirsten, Adrienne Tin, Audrey Y. Chu, Nisha Bansal, Mary F. Feitosa, Lihua Wang, Jin-Fang Chai, Massimiliano Cocca, Christian Fuchsberger, Mathias Gorski, Anselm Hoppmann, Katrin Horn, Man Li, Jonathan Marten, Damia Noce, Teresa Nutile, Sanaz Sedaghat, Gard
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
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An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Auteurs: Jun Liu, Elena Carnero-Montoro, Jenny van Dongen, Samantha Lent, Ivana Nedeljkovic, Symen Ligthart, Pei-Chien Tsai, Tiphaine C. Martin, Pooja R. Mandaviya, Rick Jansen, Marjolein J. Peters, Liesbeth Duijts, Vincent W. V. Jaddoe, Henning Tiemeier, Janine F. Felix, Gonneke Willemsen, Eco J. C. de Geus, Audrey Y. Chu, Daniel Levy, Shih-Jen Hwang, Jan Bressler, Rahul Gondalia, Elias L. Salfati, Christ
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
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Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

Auteurs: Ellis Voerman, Susana Santos, Bernadeta Patro Golab, Pilar Amiano, Ferran Ballester, Henrique Barros, Anna Bergström, Marie-Aline Charles, Leda Chatzi, Cécile Chevrier, George P. Chrousos, Eva Corpeleijn, Nathalie Costet, Sarah Crozier, Graham Devereux, Merete Eggesbø, Sandra Ekström, Maria Pia Fantini, Sara Farchi, Francesco Forastiere, Vagelis Georgiu, Keith M. Godfrey, Davide Gori, Veit Gro
Publié dans: PLOS Medicine, Numéro 16/2, 2019, Page(s) e1002744, ISSN 1549-1676
Éditeur: Public Library of Science
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A catalog of genetic loci associated with kidney function from analyses of a million individuals

Auteurs: M. Wuttke; Y. Li; M. Li; K. B. Sieber; M. F. Feitosa; M. Gorski; A. Tin; L. Wang; A. Y. Chu; A. Hoppmann; H. Kirsten; A. Giri; J. F. Chai; G. Sveinbjornsson; B. O. Tayo; T. Nutile; C. Fuchsberger; J. Marten; M. Cocca; S. Ghasemi; Y. Xu; K. Horn; D. Noce; P. J. van der Most; S. Sedaghat; Z. Yu; M. Akiyama; S. Afaq; T. S. Ahluwalia; P. Almgren; N. Amin; J. Arnlov; S. J. L. Bakker; N. Bansal; D. Bapt
Publié dans: Nature Genetics, 2019, ISSN 1061-4036
Éditeur: Nature Publishing Group
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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Auteurs: Nicole M. Warrington, Robin N. Beaumont, Momoko Horikoshi, Felix R. Day, Øyvind Helgeland, Charles Laurin, Jonas Bacelis, Shouneng Peng, Ke Hao, Bjarke Feenstra, Andrew R. Wood, Anubha Mahajan, Jessica Tyrrell, Neil R. Robertson, N. William Rayner, Zhen Qiao, Gunn-Helen Moen, Marc Vaudel, Carmen J. Marsit, Jia Chen, Michael Nodzenski, Theresia M. Schnurr, Mohammad H. Zafarmand, Jonathan P. Bradfi
Publié dans: Nature Genetics, Numéro 51/5, 2019, Page(s) 804-814, ISSN 1061-4036
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Associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth: Findings from Mendelian randomization and parental negative control studies

Auteurs: Judith S. Brand, Romy Gaillard, Jane West, Rosemary R. C. McEachan, John Wright, Ellis Voerman, Janine F. Felix, Kate Tilling, Deborah A. Lawlor
Publié dans: PLOS Medicine, Numéro 16/11, 2019, Page(s) e1002972, ISSN 1549-1676
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GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

Auteurs: Alexessander Couto Alves, N. Maneka G. De Silva, Ville Karhunen, Ulla Sovio, Shikta Das, H. Rob Taal, Nicole M. Warrington, Alexandra M. Lewin, Marika Kaakinen, Diana L. Cousminer, Elisabeth Thiering, Nicholas J. Timpson, Tom A. Bond, Estelle Lowry, Christopher D. Brown, Xavier Estivill, Virpi Lindi, Jonathan P. Bradfield, Frank Geller, Doug Speed, Lachlan J. M. Coin, Marie Loh, Sheila J. Barton,
Publié dans: Science Advances, Numéro 5/9, 2019, Page(s) eaaw3095, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
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Caesarean section, but not induction of labour, is associated with major changes in cord blood metabolome

Auteurs: Linda Marchioro, Engy Shokry, Aisling A. Geraghty, Eileen C. O’Brien, Olaf Uhl, Berthold Koletzko, Fionnuala M. McAuliffe
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
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Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

Auteurs: Nabila Kazmi, Gemma C. Sharp, Sarah E. Reese, Florianne O. Vehmeijer, Jari Lahti, Christian M. Page, Weiming Zhang, Sheryl L. Rifas-Shiman, Faisal I. Rezwan, Andrew J. Simpkin, Kimberley Burrows, Tom G. Richardson, Diana L. Santos Ferreira, Abigail Fraser, Quaker E. Harmon, Shanshan Zhao, Vincent W.V. Jaddoe, Darina Czamara, Elisabeth B. Binder, Maria C. Magnus, Siri E. Håberg, Wenche Nystad, Ell
Publié dans: Hypertension, Numéro 74/2, 2019, Page(s) 375-383, ISSN 0194-911X
Éditeur: Lippincott Williams & Wilkins Ltd.
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Impact of infant protein supply and other early life factors on plasma metabolome at 5.5 and 8 years of age: a randomized trial

Auteurs: Franca Fabiana Kirchberg, Christian Hellmuth, Martina Totzauer, Olaf Uhl, Ricardo Closa-Monasterolo, Joaquin Escribano, Dariusz Gruszfeld, Kinga Gradowska, Elvira Verduci, Benedetta Mariani, Melissa Moretti, Déborah Rousseaux, Berthold Koletzko
Publié dans: International Journal of Obesity, Numéro 44/1, 2020, Page(s) 69-81, ISSN 0307-0565
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Validated inference of smoking habits from blood with a finite DNA methylation marker set

Auteurs: Silvana C. E. Maas, Athina Vidaki, Rory Wilson, Alexander Teumer, Fan Liu, Joyce B. J. van Meurs, André G. Uitterlinden, Dorret I. Boomsma, Eco J. C. de Geus, Gonneke Willemsen, Jenny van Dongen, Carla J. H. van der Kallen, P. Eline Slagboom, Marian Beekman, Diana van Heemst, Leonard H. van den Berg, Liesbeth Duijts, Vincent W. V. Jaddoe, Karl-Heinz Ladwig, Sonja Kunze, Annette Peters, M. Arfan I
Publié dans: European Journal of Epidemiology, Numéro 34/11, 2019, Page(s) 1055-1074, ISSN 0393-2990
Éditeur: Kluwer Academic Publishers
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Associations of maternal and fetal vitamin D status with childhood body composition and cardiovascular risk factors

Auteurs: Kozeta Miliku, Janine F. Felix, Trudy Voortman, Henning Tiemeier, Darryl W. Eyles, Thomas H. Burne, John J. McGrath, Vincent W.V. Jaddoe
Publié dans: Maternal & Child Nutrition, Numéro 15/2, 2018, Page(s) e12672, ISSN 1740-8695
Éditeur: Blackwell Publishing Inc.
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Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age

Auteurs: Ahmed Elhakeem, Monika Frysz, Kate Tilling, Jon H. Tobias, Deborah A. Lawlor
Publié dans: JAMA Network Open, Numéro 2/8, 2019, Page(s) e198918, ISSN 2574-3805
Éditeur: American Medical Association
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Association of Birth Weight With Type 2 Diabetes and Glycemic Traits

Auteurs: Tao Huang, Tiange Wang, Yan Zheng, Christina Ellervik, Xiang Li, Meng Gao, Zhe Fang, Jin-Fang Chai, Tarun veer S. Ahluwalia, Yujie Wang, Trudy Voortman, Raymond Noordam, Alexis Frazier-Wood, Markus Scholz, Emily Sonestedt, Masato Akiyama, Rajkumar Dorajoo, Ang Zhou, Tuomas O. Kilpeläinen, Marcus E. Kleber, Sarah R. Crozier, Keith M. Godfrey, Rozenn Lemaitre, Janine F. Felix, Yuan Shi, Preeti Gupt
Publié dans: JAMA Network Open, Numéro 2/9, 2019, Page(s) e1910915, ISSN 2574-3805
Éditeur: American Medical Association
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Which modifiable prenatal factors mediate the relation between socio‐economic position and a child's weight and length at birth?

Auteurs: Morgane Ballon, Jérémie Botton, Anne Forhan, Blandine Lauzon‐Guillain, Maria Melchior, Fabienne El Khoury, Aurélie Nakamura, Marie Aline Charles, Sandrine Lioret, Barbara Heude
Publié dans: Maternal & Child Nutrition, Numéro 15/4, 2019, ISSN 1740-8695
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Effect of a low glycaemic index diet during pregnancy on maternal and cord blood metabolomic profiles: results from the ROLO randomized controlled trial

Auteurs: Linda Marchioro, Aisling A. Geraghty, Olaf Uhl, Engy Shokry, Eileen C. O’Brien, Berthold Koletzko, Fionnuala M. McAuliffe
Publié dans: Nutrition & Metabolism, Numéro 16/1, 2019, ISSN 1743-7075
Éditeur: BioMed Central
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A prospective population-based study of gestational vitamin D status and brain morphology in preadolescents

Auteurs: Runyu Zou, Hanan El Marroun, John J. McGrath, Ryan L. Muetzel, Manon Hillegers, Tonya White, Henning Tiemeier
Publié dans: NeuroImage, Numéro 209, 2020, Page(s) 116514, ISSN 1053-8119
Éditeur: Academic Press
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Maternal depression during pregnancy and cord blood DNA methylation: findings from the Avon Longitudinal Study of Parents and Children

Auteurs: A. C. Viuff, G. C. Sharp, D. Rai, T. B. Henriksen, L. H. Pedersen, K. J. Kyng, N. H. Staunstrup, A. Cortes, A. Neumann, J. F. Felix, H. Tiemeier, V. W. V. Jaddoe, C. L. Relton
Publié dans: Translational Psychiatry, Numéro 8/1, 2018, ISSN 2158-3188
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Deriving the Dietary Approaches to Stop Hypertension (DASH) Score in Women from Seven Pregnancy Cohorts from the European ALPHABET Consortium

Auteurs: Adrien M. Aubert, Anne Forhan, Blandine de Lauzon-Guillain, Ling-Wei Chen, Kinga Polanska, Wojciech Hanke, Agnieszka Jankowska, Sara M. Mensink-Bout, Liesbeth Duijts, Matthew Suderman, Caroline L. Relton, Sarah R. Crozier, Nicholas C. Harvey, Cyrus Cooper, Fionnuala M. McAuliffe, Cecily C. Kelleher, Catherine M. Phillips, Barbara Heude, Jonathan Y. Bernard
Publié dans: Nutrients, Numéro 11/11, 2019, Page(s) 2706, ISSN 2072-6643
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Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health: The Early Nutrition Project Recommendations

Auteurs: Berthold Koletzko, K.M. Godfrey, Lucilla Poston, Hania Szajewska, Johannes B. van Goudoever, Marita de Waard, Brigitte Brands, Rosalie M. Grivell, Andrea R. Deussen, Jodie M. Dodd, Bernadeta Patro-Golab, Bartlomiej M. Zalewski
Publié dans: Annals of Nutrition and Metabolism, Numéro 74/2, 2019, Page(s) 93-106, ISSN 0250-6807
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Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis

Auteurs: Jacob P. Thyssen, Tarunveer S. Ahluwalia, Lavinia Paternoster, Natalia Ballardini, Anna Bergström, Erik Melén, Bo L. Chawes, Jakob Stokholm, Jonathan O'B Hourihane, Donnchadh M. O'Sullivan, Peter Bager, Mads Melbye, Mariona Bustamante, Maties Torrent, Ana Esplugues, Liesbeth Duijts, Chen Hu, Niels J. Elbert, Suzanne G. M. A. Pasmans, Tamar E. C. Nijsten, Andrea Berg, Marie Standl, Tamara Schikow
Publié dans: Allergy, 2020, ISSN 0105-4538
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Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American, and Australian cohorts

Auteurs: S Santos, E Voerman, P Amiano, H Barros, LJ Beilin, A Bergström, M‐A Charles, L Chatzi, C Chevrier, GP Chrousos, E Corpeleijn, O Costa, N Costet, S Crozier, G Devereux, M Doyon, M Eggesbø, MP Fantini, S Farchi, F Forastiere, V Georgiu, KM Godfrey, D Gori, V Grote, W Hanke, I Hertz‐Picciotto, B Heude, M‐F Hivert, D Hryhorczuk, R‐C Huang, H Inskip, AM Karvonen, LC Kenny, B Koletzko, LK Kü
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Causal Inference in Environmental Epidemiology

Auteurs: Neil Pearce, Jan P. Vandenbroucke, Deborah A. Lawlor
Publié dans: Epidemiology, Numéro 30/3, 2019, Page(s) 311-316, ISSN 1044-3983
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Commercial complementary food use amongst European infants and children: results from the EU Childhood Obesity Project

Auteurs: Melissa A. Theurich, Marta Zaragoza-Jordana, Veronica Luque, Dariusz Gruszfeld, Kinga Gradowska, Annick Xhonneux, Enrica Riva, Elvira Verduci, Pascale Poncelet, Louiza Damianidi, Berthold Koletzko, Veit Grote
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Éditeur: Dr. Dietrich Steinkopff Verlag
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Are All Breast-fed Infants Equal? Clustering Metabolomics Data to Identify Predictive Risk Clusters for Childhood Obesity

Auteurs: Franca Fabiana Kirchberg, Veit Grote, Dariusz Gruszfeld, Piotr Socha, Ricardo Closa-Monasterolo, Joaquin Escribano, Elvira Verduci, Benedetta Mariani, Jean-Paul Langhendries, Pascale Poncelet, Berthold Koletzko, Christian Hellmuth
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Maternal Early‐Pregnancy Glucose Concentrations and Liver Fat Among School‐Age Children

Auteurs: Madelon L. Geurtsen, Rama J. Wahab, Janine F. Felix, Romy Gaillard, Vincent W.V. Jaddoe
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Advancing tools for human early lifecourse exposome research and translation (ATHLETE): Project overview

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Impaired glucose regulation, depressive symptoms, and health-related quality of life

Auteurs: Jannica S Selenius, Niko S Wasenius, Hannu Kautiainen, Minna Salonen, Mikaela von Bonsdorff, Johan G Eriksson
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Perinatal Polyunsaturated Fatty Acid Status and Obesity Risk

Auteurs: H. Demmelmair, B. Koletzko
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The influence of Epstein‐Barr virus and cytomegalovirus on childhood respiratory health: A population‐based prospective cohort study

Auteurs: Evelien R. Meel, Vincent W. V. Jaddoe, Irwin K. M. Reiss, Menno C. Zelm, Johan C. Jongste, Henriëtte A. Moll, Liesbeth Duijts
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Epigenome-wide associations between observed maternal sensitivity and offspring DNA methylation: a population-based prospective study in children

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Lifestyle intervention strategies in early life to improve pregnancy outcomes and long-term health of offspring: a narrative review

Auteurs: Romy Gaillard, John Wright, Vincent W.V. Jaddoe
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The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses

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Test, Trace and Learn: lessons about COVID-19 from young people

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Maternal blood pressure and hypertensive disorders during pregnancy and childhood respiratory morbidity: the Generation R Study

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Dietary Quality and Dietary Inflammatory Potential During Pregnancy and Offspring Emotional and Behavioral Symptoms in Childhood: An Individual Participant Data Meta-analysis of Four European Cohorts

Auteurs: Kinga Polanska, Pawel Kaluzny, Adrien M. Aubert, Jonathan Y. Bernard, Liesbeth Duijts, Hanan El Marroun, Wojciech Hanke, James R. Hébert, Barbara Heude, Agnieszka Jankowska, Giulia Mancano, Sara M. Mensink-Bout, Caroline Relton, Nitin Shivappa, Matthew Suderman, Elzbieta Trafalska, Ewelina Wesolowska, Raquel Garcia-Esteban, Mònica Guxens, Maribel Casas, Catherine M. Phillips
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Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: Meta-analysis in six European population-based cohorts

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Associations of Hair Cortisol Concentrations with General and Organ Fat Measures in Childhood

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Cognitive mediation in people with dementia: Development, structural, and construct validity of the first dementia‐specific measure

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Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

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Body fat, cardiovascular risk factors and brain structure in school-age children

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Common Polygenic Variations for Psychiatric Disorders and Cognition in Relation to Brain Morphology in the General Pediatric Population

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Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

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Birthweight DNA methylation signatures in infant saliva

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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

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Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms

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Nutritional Adequacy of Commercial Complementary Cereals in Germany

Auteurs: Melissa A. Theurich, Berthold Koletzko, Veit Grote
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Association of medically assisted reproduction with offspring cord blood DNA methylation across cohorts.

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Predictors of maternal dietary quality and dietary inflammation during pregnancy: An individual participant data meta-analysis of seven European cohorts from the ALPHABET consortium

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Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach

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Physical heaviness of work and sitting at work as predictors of mortality: a 26-year follow-up of the Helsinki Birth Cohort Study

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Population estimates and determinants of severe maternal thinness in India

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A population-based study on associations of stool microbiota with atopic diseases in school-age children

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A systematic review and meta-analysis of school-based interventions with health education to reduce body mass index in adolescents aged 10 to 19 years

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Maternal polyunsaturated fatty acids during pregnancy and offspring brain development in childhood

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Cohort Profile: 46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966)

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Prenatal exposure to non‐steroidal anti‐inflammatory drugs (NSAIDs) and neurodevelopmental outcomes in children

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Epigenetic age acceleration and cardiovascular outcomes in school-age children: The Generation R Study

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Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence

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Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation

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Alcohol use and brain morphology in adolescence: A longitudinal study in three different cohorts

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Determination of saliva epigenetic age in infancy, and its association with parental socio-economic characteristics and pregnancy outcomes

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Innovative approach for first-trimester fetal organ volume measurements using a Virtual Reality system: The Generation R Next Study

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Implications of the Developmental Origins of Health and Disease concept for policy-making

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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

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Visceral adiposity and respiratory outcomes in children and adults: a systematic review

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