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Scaling-up Packages of Interventions for Cardiovascular disease prevention in selected sites in Europe and Sub-Saharan Africa: An implementation research (SPICES Project)

Objective

The overall research objective of the SPICES project is to implement and evaluate a comprehensive CVD prevention and control program in five settings: a rural & semi-urban community in a low-income country (Uganda), middle income (South Africa) and vulnerable groups in three high-income countries (Belgium, France and United Kingdom) as well as to identify and compare the barriers and facilitators across study contexts. The project will be evaluated using a mix of formative assessments; pre/post and trial designs. At the beginning of the project, we will conduct baseline assessments including literature reviews, formative studies, household surveys (where feasible) and learn lessons from other projects to understand healthcare and lifestyle practices, barriers, and facilitators. A cost-effectiveness and cost benefit analysis will be included. In addition, the teams will conduct site exchanges visits to learn from each other and organise policy dialogues to ensure sustainability and maximise impact of the interventions. The implementation outcomes—acceptability, adoption, appropriateness, feasibility, fidelity, implementation cost, coverage, and sustainability will be evaluated – in order to understand the factors affecting the implementation, the processes, and the accruing results. The intervention of the SPICES project will aim to: (1) improve patients ’risk profiles (LDL-cholesterol, blood pressure, HbA1c (among patients with diabetes), modify lifestyles (diet and exercise and smoking cessation) and achieve recommended cholesterol, blood pressure and glycaemic control targets; (2) increase proportion of patients receiving appropriate BP, cholesterol and diabetes medication; (3) and mitigate the number of people developing complications such a stroke and myocardial infarction.

Call for proposal

H2020-SC1-2016-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action
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Coordinator

UNIVERSITEIT ANTWERPEN
Address
Prinsstraat 13
2000 Antwerpen
Belgium
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 599 662,50

Participants (6)

MAKERERE UNIVERSITY
Uganda
EU contribution
€ 901 837,50
Address
Main Campus
256 Kampala
Activity type
Higher or Secondary Education Establishments
CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE BREST
France
EU contribution
€ 1 022 137,50
Address
Avenue Marechal Foch 5
29609 Brest
Activity type
Research Organisations
THE UNIVERSITY OF MANCHESTER

Participation ended

United Kingdom
EU contribution
€ 61 950,10
Address
Oxford Road
M13 9PL Manchester
Activity type
Higher or Secondary Education Establishments
THE NOTTINGHAM TRENT UNIVERSITY
United Kingdom
EU contribution
€ 651 671,25
Address
50 Shakespeare Street
NG1 4FQ Nottingham
Activity type
Higher or Secondary Education Establishments
University of Limpopo
South Africa
EU contribution
€ 788 125
Address
P/bag 1106
0727 Polokwane
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF SUSSEX
United Kingdom
EU contribution
€ 876 654,90
Address
Sussex House Falmer
BN1 9RH Brighton
Activity type
Higher or Secondary Education Establishments