Deliverables Documents, reports (14) Minutes of the Steering Committee meeting at M36 Minutes of the 6th Steering Committee meeting Minutes of the Steering Committee meeting at M30 Minutes of the 5th Steering Committee meeting Scientific action check meeting M24 Scientific action check meeting related to reporting period 1 Minutes of the Steering Committee meetings at M12 Minutes of the 2nd Steering Committee meeting List of ICT system specifications Based on all partners’ available technologies as on its own insight on future biomedical devices, this deliverable will define the specification of the Lab on Chip’s key parameters including size, form factor, throughput, maximum sensitivity, available power, frequency range, waveform modulation, ambient sensitivity Minutes of the Steering Committee meeting at M18 Minutes of the 3rd Steering Committee meeting Biological protocols This deliverable will define the protocols to be used for biological analysis, including: - cell culture protocol (UNILIM, ENEA and UNIPD) - protocols to isolate MB and GM CSC (ENEA, UNIPD and UNILIM) - in vitro ionizing radiations protocol (UNILIM and ENEA) - in vivo ionizing radiations protocol (ENEA) - tumour graft protocols for MB and GBM (UNIPD and ENEA). Minutes of the Final Steering Committee meeting at M48 Minutes of the 7th and last Steering Committee meeting Minutes of the Steering Committee meetings at M6 Minutes of the 1st Steering Committee meeting In vitro CSCs isolation and characterization in human GBM and MB models "This deliverable will present the results and the validation of the ""out of lab on chip"" CSCs isolation and biological characterization in GBM and MB cell lines according to the protocols defined in Task 1.1." Minutes of the Steering Committee meeting at M24 Minutes of the 4th Steering Committee meeting Scientific action check meeting M12 Scientific action check meeting related to project end of first year. Synergic effects of EM field/radiation dose to sensitize CSC in vivo This deliverable will presents results of in vivo tests combining non-ioninzing and ionizing radiation exposure of tumorand the evaluation of a possible reduction of standard treatment dose if combined with EM pretreatment of CSCs with equivalent efficiency. Scientific action check meeting M42 Scientific action check meeting related to reporting period 1 Open Research Data Pilot (1) Data Management Plan A data Management Plan will be set to define data generated by the project to be kept confidential Websites, patent fillings, videos etc. (3) Stakeholders management workshop To prepare the next step of the technology development, we beleve that it is necessary to convince and mobilize both the medical and industrial worlds. To enhance the project visibility and stakeholder awareness, a “Stakeholders management” workshop will be organized in order to disseminate largely the project outcome and prepare for future R&D project or investments. Project identity set (logo, brochure…) This deliverable will deal with SUMACTEC visual identidy for efficient communication: logo, brochure, flyer... Public Website To promote the project and facilitate the communication and dissemination a public Website will be created and dedicatedfor SUMCASTEC. This website will display information about the project and will also be used as a resource for internal and external information dissemination. This website will also include a secure section for intraconsortium document share and exchange. Publications Peer reviewed articles (8) Microsecond Pulsed Electric Fields: An Effective Way to Selectively Target and Radiosensitize Medulloblastoma Cancer Stem Cells Author(s): Mirella Tanori, Arianna Casciati, Alessandro Zambotti, Rosanna Pinto, Isabella Gianlorenzi, Alessandro Pannicelli, Paola Giardullo, Barbara Benassi, Carmela Marino, Mariateresa Mancuso, Caterina Merla Published in: International Journal of Radiation Oncology*Biology*Physics, Issue 109/5, 2021, Page(s) 1495-1507, ISSN 0360-3016 Publisher: Elsevier BV DOI: 10.1016/j.ijrobp.2020.11.047 Microdosimetry Using Rhodamine B Within Macro- and Microsystems for Radiofrequency Signals Exposures of Biological Samples Author(s): Amani Nefzi, Lynn Carr, Claire Dalmay, Arnaud Pothier, Philippe Leveque, Delia Arnaud-Cormos Published in: IEEE Transactions on Microwave Theory and Techniques, Issue 68/3, 2020, Page(s) 1142-1150, ISSN 0018-9480 Publisher: Institute of Electrical and Electronics Engineers DOI: 10.1109/tmtt.2019.2950191 High-voltage 10 ns delayed paired or bipolar pulses for in vitro bioelectric experiments Author(s): Rosa Orlacchio, Lynn Carr, Cristiano Palego, Delia Arnaud-Cormos, Philippe Leveque Published in: Bioelectrochemistry, Issue 137, 2021, Page(s) 107648, ISSN 1567-5394 Publisher: Elsevier BV DOI: 10.1016/j.bioelechem.2020.107648 Push–pull configuration of high-power MOSFETs for generation of nanosecond pulses for electropermeabilization of cells Author(s): Ilan Wyn Davies; Caterina Merla; Arianna Casciati; Mirella Tanori; Alessandro Zambotti; Mariateresa Mancuso; John Bishop; Malcom White; Cristiano Palego; Christopher Hancock Published in: International Journal of Microwave and Wireless Technologies, 2019, Page(s) 1–13., ISSN 1759-0795 Publisher: Cambridge University Press DOI: 10.1017/s1759078719000576 Experimental observation of a photonic hook Author(s): I. V. Minin, O. V. Minin, G. M. Katyba, N. V. Chernomyrdin, V. N. Kurlov, K. I. Zaytsev, L. Yue, Z. Wang, D. N. Christodoulides Published in: Applied Physics Letters, Issue 114/3, 2019, Page(s) 031105, ISSN 0003-6951 Publisher: American Institute of Physics DOI: 10.1063/1.5065899 UHF-Dielectrophoresis Crossover Frequency as a New Marker for Discrimination of Glioblastoma Undifferentiated Cells Author(s): Remi Manczak, Sofiane Saada, Thomas Provent, Claire Dalmay, Barbara Bessette, Gaelle Begaud, Serge Battu, Pierre Blondy, Marie-Odile Jauberteau, Canan Baristiran Kaynak, Mehmet Kaynak, Cristiano Palego, Fabrice Lalloue, Arnaud Pothier Published in: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 2019, Page(s) 1-1, ISSN 2469-7249 Publisher: IEEE DOI: 10.1109/jerm.2019.2895539 Human Medulloblastoma Cell Lines: Investigating on Cancer Stem Cell-Like Phenotype Author(s): Arianna Casciati, Mirella Tanori, Rémi Manczak, Sofiane Saada, Barbara Tanno, Paola Giardullo, Elena Porcù, Elena Rampazzo, Luca Persano, Giampietro Viola, Claire Dalmay, Fabrice Lalloué, Arnaud Pothier, Caterina Merla, Mariateresa Mancuso Published in: Cancers, Issue 12/1, 2020, Page(s) 226, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers12010226 A New Label-Free Approach to Glioblastoma Cancer Stem Cell Sorting and Detection Author(s): Aurélie Lacroix, Elise Deluche, Ling Yan Zhang, Claire Dalmay, Carole Mélin, Jonathan Leroy, Meissa Babay, Christophe Morand Du Puch, Stéphanie Giraud, Barbara Bessette, Gaëlle Bégaud, Sofiane Saada, Christophe Lautrette, Arnaud Pothier, Serge Battu, Fabrice Lalloué Published in: Analytical Chemistry, Issue 91/14, 2019, Page(s) 8948-8957, ISSN 0003-2700 Publisher: American Chemical Society DOI: 10.1021/acs.analchem.9b00913 Conference proceedings (71) A Novel Ultrashort Electric Field Pulse Generator using Avalanche Breakdown Transistors and the Open Circuit Transmission Line Technique for Nanosecond Electroporation Author(s): I. W. Davies and C. P. Hancock Published in: 2019 3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.4701937 ltrashort electric pulses: an effective way to target cancer stem cells Author(s): M. Tanori ENEA, Rome ; A. Casciati; P. Giardullo; B. Tanno; A. Zambotti; B. Benassi; R. Pinto; I. Davis; C. Palego; C. Hancock; C. Marino; M. Mancuso; C. Merla Published in: 2019 3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine, and Food & Environmental Technologies, 2019 Publisher: zenodo DOI: 10.5281/zenodo.3612388 Investigating the role of pulsed electric fields as radiosensitizers of medulloblastoma cancer stem cells Author(s): Mirella Tanori , Arianna Casciati, Paola Giardullo, Alessandro Zambotti, Rosanna Pinto, Carmela Marino, Caterina Merla and Mariateresa Mancuso Published in: 2019 65th Annual Meeting of the Radiation Research Society, 2019 Publisher: Zenodo The effect of nsPEF on glioblastoma cancer-like stem cell transcription and protein expression Author(s): Lynn Carr; Cristiano Palego; Sofiane Saada; Barbara Bessette; Arnaud Pothier; Delia Arnaud-Cormos; Philippe Leveque; Fabrice Lalloué Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4700367 Dielectric parameters extraction and modeling of brain cancer stem-like cells Author(s): C. Merla, C. Palego, S. Ghamal, N. Karim, R. Pinto, M. Tanori, A. Casciati, A. Zambotti, M. Mancuso Published in: 2020 IEEE IMBIOC conference Workshop, 2020 Publisher: Zenodo Immature cancer cell discrimination using combined high frequency Electromagnetic Fields and dielectrophoresis forces Author(s): C. Dalmay, R. Manczak, S. Saada, T. Provent, B. Bessette, A. Casciati, M. Tanori, E Porcù, E Rampazzo, L Persano, C. Baristiran Kaynak, M. Kaynak, C. Palego, G. Viola, C. Merla, M. Mancuso, F. Lalloue, A. Pothier Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4700388 Discrimination Cellulaire par Dielectrophorèse Ultra Haute Fréquence : Etude des Fréquences de Transition de Cellules de Glioblastomes Author(s): R. Manczak, S. Saada, T. Provent, C. Dalmay, B. Bessette, G. Begaud, S. Battu, P. Blondy, M.O. Jauberteau, C. Baristiran Kaynak, M. Kaynak, C. Palego, F. Lalloue, A. Pothier Published in: 2019 JNM conference, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.2652355 Continuous Cell Sorting by High Frequencies Dielectrophoresis Author(s): T. Provent, R. Manczak, S. Saada, C.Dalmay, B. Bessette, P. Blondy, G. Begaud, S. Battu, M.O. Jauberteau, F. Lalloué, A. Pothier Published in: 2019 Plumee conference, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.2652342 Radio Frequency sensors & lab-on-chip technologies: news opportunities for biomedical diagnosis Author(s): A. Pothier , M. Babay, C. Dalmay , D. Cordeau, R. Manczak, S. Saada, B. Bessette, F. Lalloue, C. Merla , M. Mancuso, M. Tanori3, A. Casciati,E. Porcù, E. Rampazzo ,L. Persano, G.Viola, C. Palego, E.C Durmaz, C.B Kayank and M. Kaynak Published in: 2021 EUMW Conference Workshop, 2021 Publisher: IEEE Ultra-High Frequencies continuous biological cell sorting based on repulsive and low dielectrophoresis forces Author(s): Thomas Provent, Remi Manczak, Sofiane Saada, Claire Dalmay, Barbara Bessette, Gaelle Begaud, Serge Battu, Pierre Blondy, Marie Odile Jauberteau, Fabrice Lalloue, Arnaud Pothier Published in: 2019 IEEE MTT-S International Microwave Symposium (IMS), 2019, Page(s) 224-227, ISBN 978-1-7281-1309-8 Publisher: IEEE DOI: 10.1109/mwsym.2019.8701063 Human medulloblastoma cell lines: investigating on cancer stem cell-like phenotype Author(s): A. Casciati; M. Tanori; B. Tanno; P. Giardullo; E. Porcù; E. Rampazzo; L. Persano; G. Viola; R. Manczak; S. Saada; C. Dalmay; F. Lalloué; A. Pothier; C. Merla; M. Mancuso; Published in: 2019 3rd SUNRISE Meeting on New Advances in Cancer Stem Cells, 2019 Publisher: zenodo DOI: 10.5281/zenodo.3603294 Des ondes électromagnétiques peuvent-elles être utilisées pour identifier et neutraliser des cellules souches cancéreuses? Author(s): A. Pothier, R. Manczak, S. Saada, T. Provent, M. Tanori , A. Casciati , E. Porcù , E. Rampazzo , C. Dalmay, B. Bessette, G. Begaud, S. Battu, C, Merla , B. Tanno , L. Persano ,P. Blondy, M.O. Jauberteau, C. Baristiran Kaynak, M. Kaynak, C. Palego, G.Viola, M. Mancuso , F. Lalloue Published in: 2019 JNM conference, 2019 Publisher: Zenodo Lab-On-Chip platform for neutralization of cancer stem cells Author(s): Cristiano Palego, Nissar Karim, Amira Eltokhy, Lynn Carr, Emre Can, Canan Baristiran, Mehmet Kaynak, Arnaud Pothier, Delia Arnaud-Cormos & Philippe Leveque Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4707171 Microsystem and Lab-On-Chip technologies might promote future generation of new tools for biological analysis Author(s): T. Provent, R. Manczak, S. Saada, C.Dalmay, B. Bessette, P. Blondy, G. Begaud, S. Battu, M.O. Jauberteau, F. Lalloué, A. Pothier Published in: 2019 SUMCASTEC Biomedical Applications of Electromagnetic Energy Workshop, 2019 Publisher: SUMCASTEC DOI: 10.5281/zenodo.3408571 Microfluidic device for high-frequency dielectrophoresis characterization and single-cell discrimination Author(s): Elisa Lambert, Elodie Barthout, Thomas Provent, Rémi Manczak , Sofiane Saada, Claire Dalmay, Barbara Bessette, Fabrice Lalloué , Arnaud Pothier Published in: 2021 TECH DAY: Single Cell Analysis Conference, 2021 Publisher: Zenodo Design and Implementation of Injection Locked Oscillator Biosensors Author(s): M. Babay, C. Dalmay, B. Barelaud, E.C. Durmaz, C. Baristiran Kaynak, M. Kaynak, D. Cordeau, A. Pothier Published in: 2019 49th European Microwave Conference (EuMC), 2019, Page(s) 168-171, ISBN 978-2-87487-055-2 Publisher: IEEE DOI: 10.23919/eumc.2019.8910746 BiCMOS integrated microfluidic cell sorting platform for CSC cell study Author(s): Arnaud Pothier Published in: 2018 Sumcastec workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Zenodo Progress in dielectric spectroscopy for biological cell characterization and cell sorting at MHz frequencies Author(s): A. Pothier; R. Manczak; S. Saada; M. Tanori; A. Casciati; E. Porcù; E. Rampazzo; C. Dalmay; B. Bessette; G. Begaud; S. Battu; C. Merla; B. Tanno; L. Persano; P. Blondy; M.O. Jauberteau; C. Baristiran Kaynak; M. Kaynak; C. Palego; G. Viola; M. Mancuso; F. Lalloue Published in: 2019 Européan Microwave Conference Week conference Workshop, 2019 Publisher: Zenodo High frequency Electromagnetic Fields sensing based on lab-on-chip technology for Cancer Stem Cells Isolation and Analysis Author(s): Claire Dalmay, Barbara Bessette, Fabrice Lalloué, Arnaud Pothier Published in: 2020 IEEE IMBIOC conference Workshop, 2020 Publisher: Zenodo HF-Dielectrophoresis crossover frequency measurements do allow discriminating cancerous stem cells from differentiated cells Author(s): A. Pothier, R. Manczak, S. Saada, T. Provent, M. Tanori , A. Casciati , E. Porcù , E. Rampazzo , C. Dalmay, B. Bessette, G. Begaud, S. Battu, C, Merla , B. Tanno , L. Persano ,P. Blondy, M.O. Jauberteau, C. Baristiran Kaynak, M. Kaynak, C. Palego, G.Viola, M. Mancuso , F. Lalloue Published in: 2019 SUMCASTEC Biomedical Applications of Electromagnetic Energy Workshop, 2019 Publisher: Zenodo A Novel Ultrashort Electric Field Pulse Generator using Avalanche Breakdown Transistors and the Open Circuit Transmission Line Technique for Nanosecond Electroporation Author(s): Ilan Wyn Davies; Christopher Paul Hancock Published in: 2019 IEEE Asia-Pacific Microwave Conference, 2019 Publisher: IEEE DOI: 10.1109/apmc46564.2019.9038660 Push-Pull Configuration of High Power MOSFETs for Generation of Nanosecond Pulses for Electropermeabilization of Medulobastoma Cells Author(s): I. W. Davies Published in: 2019 Bangor University College of Environmental Sciences and Engineering (CoESE) PhD conference, 2019 Publisher: zenodo Discrimination of Glioblastoma Cancer Stem Cells by their UHF-Dielectrophoresis Crossover Frequency Author(s): S. Saada, R. Manczak, B. Bessette, L Persano, E Percu, G. Begaud, C. Dalmay, S Battu, P. Blondy, M. Inac, C. Baristiran Kaynak, M. Kaynak, C. Palego, G Viola, M.O. Jauberteau, A. Pothier, F. Lalloué Published in: 2018 11th International Conference on Cancer Stem Cells and Oncology Research, 2018 Publisher: Zenodo DOI: 10.5281/zenodo.4699734 Rhodamine B Temperature Dosimetry of Biological Samples Interacting with Electromagnetic Fields in Macrosystems Author(s): Amani Nefzi, Lynn Carr, Claire Dalmay, Arnaud Pothier, Philippe Leveque, Delia Arnaud-Cormos Published in: 2019 IEEE MTT-S International Microwave Symposium (IMS), 2019, Page(s) 1454-1457, ISBN 978-1-7281-1309-8 Publisher: IEEE DOI: 10.1109/mwsym.2019.8700784 Bipolar nanosecond pulse electric field generator using open circuit transmission line technique andavalanche transistors for nanosecond electroporation Author(s): Ilan Davies1 & Christopher Hancock Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4707197 Lab-On-A-Chip For Cellular Analysis By Dielectric Spectroscopy Based On Injection Locked Oscillators Author(s): M. Babay, C. Dalmay, B. Barelaud, M. Kaynak, E. Can Durmaz, C. Baristiran Kaynak D.Cordeau, A. Pothier Published in: 2019 Plumee conference, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.2652075 Stem Glioblastoma Cancer Stem like Cells discrimination by UHF-Dielectrophoresis Crossover Frequency Author(s): S. Saada, R. Manczak, B. Bessette, L Persano, E Percu, G. Begaud, C. Dalmay, S Battu, P. Blondy, M. Inac, C. Baristiran Kaynak, M. Kaynak, C. Palego, G Viola, M.O. Jauberteau, A. Pothier, F. Lalloué Published in: 2019 Brain Tumor Meeting, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.3408553 Electromanipulate biological cells with high frequency signals: a new way to characterize cell aggressiveness in the frame of cancer treatment Author(s): R. Manczak; S. Saada; T. Provent; C. Dalmay; B. Bessette; C.Merla; B. Tanno; M. Mancuso; C. Baristiran Kaynak; M. Kaynak; C. Palego; F. Lalloue; A. Pothier Published in: 2019 IEEE IMS conference Workhop, 2019 Publisher: IEEE Dielectric Spectroscopy and RF and Microwave Passive Microsystems for Biological Applications and Discrimination of Cells Author(s): A. Pothier, C.Dalmay, F. Hjeij P. Blondy, F.Lalloué, B.Bessette, M.Kaynak, C. Palego Published in: 2017 IEEE MTT-S International Microwave Symposium (IMS) Workshop, 2017 Publisher: IEEE Biological cell discrimination based on their high frequency dielectropheretic signatures at UHF frequencies Author(s): F. Hjeij, C. Dalmay, B. Bessette, G. Begaud, A. Bessaudou, Pierre Blondy, M. O. Jauberteau, F. Lalloue, C. Baristiran Kaynak, Mehmet Kaynak, W. Gamal, C. Palego, Arnaud Pothier Published in: 2017 IEEE MTT-S International Microwave Symposium (IMS), 2017, Page(s) 533-536, ISBN 978-1-5090-6360-4 Publisher: IEEE DOI: 10.1109/MWSYM.2017.8058618 Oxide surface roughness optimization of BiCMOS beol wafers for 200 mm wafer level microfluidic packaging based on fusion bonding Author(s): M. Inac, M. Wietstruck, A. Goritz, B. Cetindogan, C. Baristiran-Kaynak, M. Lisker, A. Kruger, A. Trusch, U. Saarow, P. Heinrich, T. Voss, M. Kaynak Published in: 2017 IEEE 19th Electronics Packaging Technology Conference (EPTC), 2017, Page(s) 1-4, ISBN 978-1-5386-3042-6 Publisher: IEEE DOI: 10.1109/eptc.2017.8277523 BiCMOS Integrated Microfluidic Packaging by Wafer Bonding for Lab-on-Chip Applications Author(s): Mesut Inac, Matthias Wietstruck, Alexander Goritz, Barbaros Cetindogan, Canan Baristiran-Kaynak, Steffen Marschmeyer, Mirko Fraschke, Thomas Voss, Andreas Mai, Cristiano Palego, Arnaud Pothier, Mehmet Kaynak Published in: 2017 IEEE 67th Electronic Components and Technology Conference (ECTC), 2017, Page(s) 786-791, ISBN 978-1-5090-6315-4 Publisher: IEEE DOI: 10.1109/ECTC.2017.153 BiCMOS Embedded Microfluidic Technology Based on Wafer Bonding Techniques for Biosensor Applications Author(s): M. Inac, M. Wietstruck, A. Göritz, B. Cetindogan, C. Baristiran Kaynak, S. Marschmeyer, M. Fraschke, T. Voss, A. Mai, C. Palego, A. Pothier, M. Kaynak Published in: 2017 MikroSystemTechnik Kongress (MST 2017), 2017, Page(s) 273-276, ISBN 978-3-8007-4491-6 Publisher: VDE Verband der Elektrotechnik Elektronik Informationstechnik BiCMOS/microfluidics lab-on-chip Author(s): C. Palego, C. Hancock, A. Porch, M. Kaynak Published in: 2017 Engineering Wales Conference, 2017 Publisher: National Research Network in Advanced Engineering and Materials BiCMOS Microfluidic Microwave Platform for Biological Cell Sensing and Manipulation Author(s): B. Cetindogan, ,M. Inac, A. Goritz, M. Wietstruck, C. Baristiran-Kaynak, C. Palego, A. Pothier, ,M. Kaynak Published in: 2017 IEEE MTT-S International Microwave Symposium (IMS), Issue Workshop on Thermal vs non-thermal effects of electromagnetic waves for biomedical application, 2017 Publisher: IEEE Advanced RF, Microwave and Millimeter Wave Energy Based Systemsto Address A Range of Unmet and Growing Clinical Needs Author(s): C. Hancock Published in: 2017 IEEE MTT-S International Microwave Symposium (IMS) Workshop, Issue Workshop on Thermal vs non-thermal effects of electromagnetic waves for biomedical application, 2017 Publisher: IEEE The Effect of Surface Optimization on Post-grinding Yield of 200 mm Wafer Level Packaging Applications Author(s): Mesut Inac, Matthias Wietstruck, Alexander Goritz, Barbaros Cetindogan, Canan Baristiran-Kaynak, Marco Lisker, Andreas Kruger, Ulrike Saarow, Patric Heinrich, Thomas Voss, Kasim Altin, Mehmet Kaynak Published in: 2018 7th Electronic System-Integration Technology Conference (ESTC), 2018, Page(s) 1-4, ISBN 978-1-5386-6814-6 Publisher: IEEE DOI: 10.1109/ESTC.2018.8546457 Push-Pull Configuration of High Power MOSFETs for Generation of Nanosecond Pulses for Electropermeabilization of Isolated Cancer Stem Cells Author(s): I.W. Davies, C. Merla, M. Tanori, A. Zambotti, J. Bishop, C. Palego, C. P. Hancock Published in: 2018 48th European Microwave Conference (EuMC), 2018, Page(s) 866-869, ISBN 978-2-87487-051-4 Publisher: IEEE DOI: 10.23919/EuMC.2018.8541734 Electropermeabilization of Isolated Cancer Stem Cells with a Novel and Versatile Nanosecond Pulse Generator Author(s): I. W. Davies, C. Merla, A. Casciati, A. Zambotti, J. Bishop, G. Hodgkins, C. Palego, C. P. Hancock Published in: 2018 IEEE International Microwave Biomedical Conference (IMBioC), 2018, Page(s) 106-108, ISBN 978-1-5386-5918-2 Publisher: IEEE DOI: 10.1109/IMBIOC.2018.8428941 Permittivity measurements of brain cancer cell solutions: towards the electric characterisation of single cancer stem cells Author(s): Gamal, Wesam; Pinto, Rosanna; Tanori, Mirella; Casciati, Arianna; Mancuso, Mariateresa; Persano, Luca; Viola, Giampietro; Saada, Sofiane; Bessette, Barbara; Lalloue, Fabrice; Pothier, Arnaud; Palego, Cristiano; Merla, Caterina Published in: 2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med), 2018 Publisher: EMF-Med DOI: 10.5281/zenodo.1443523 High-Frequency Dielectrophoresis Characterization of Differentiated vs Undifferentiated Medulloblastoma Cells Author(s): Remi Manczak, Sofiane Saada, Mirella Tanori, Arianna Casciati, Claire Dalmay, Barbara Bessette, Gaelle Begaud, Serge Battu, Pierre Blondy, Marie Odile Jauberteau, Canan Baristiran Kaynak, Mehmet Kaynak, Cristiano Palego, Caterina Merla, Barbara Tanno, Mariateresa Mancuso, Fabrice Lalloue, Arnaud Pothier Published in: 2018 EMF-Med 1st World Conference on Biomedical Applications of Electromagnetic Fields (EMF-Med), 2018, Page(s) 1-2, ISBN 978-9-5329-0079-8 Publisher: IEEE DOI: 10.23919/EMF-MED.2018.8526006 Tracking Cancer Cells with Microfluidic High Frequency DEP Cytometer Implemented on BiCMOS Lab-on-Chip Platform Author(s): R. Manczak, F. Hjeij, T. Provent, S. Saada, C. Dalmay, B. Bessette, G. Begaud, S. Battu, P. Blondy, M.O. Jauberteau, F. Lalloue, M. Inac, C. Baristiran Kaynak, M. Kaynak, C. Palego, A. Pothier Published in: 2018 IEEE/MTT-S International Microwave Symposium - IMS, 2018, Page(s) 104-107, ISBN 978-1-5386-5067-7 Publisher: IEEE DOI: 10.1109/MWSYM.2018.8439466 New therapeutic strategy for medulloblastoma: µs pulse electric fields exposure targeting cancer stem cells to promote radiosensitization Author(s): Mirella Tanori, Arianna Casciati, Barbara Tanno, Paola Giardullo, Alessandro Zambotti, Carmela Marino, Caterina Merla, Mariateresa Mancuso Published in: 2019 International Conference on Radiation in Various Fields of Research (RAD 2019), 2019 Publisher: RAD 2019 Ultra-High Frequencies continuous biological cell sorting based on repulsive and low dielectrophoresis forces, Author(s): T. Provent, R. Manczak, S. Saada, C.Dalmay, B. Bessette, P. Blondy, G. Begaud, S. Battu, M.O. Jauberteau, F. Lalloué, A. Pothier Published in: 2019 IEEE MTT-S International Microwave Symposium (IMS), 2019 Publisher: IEEE On-chip Flow Cell Sorting System Based on High frequency Dielectrophoresis implemented on CMOS technology Author(s): R Manzac, A Pothier. C. Dalamy, P. Blondy, S. Saada, F. Lalloue Published in: 2018 Workshop of GDR Micronanofluidics, 2018 Publisher: Gdr Micronanofluidics Ultra-short pulsed electric fields: a first study on cancer stem cells Author(s): C. Merla Published in: 2018 Workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Bangor University BiCMOS integrated microfluidic cell sorting platform for CSC cell study Author(s): A Pothier Published in: 2018 Workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Bangor University Isolation and characterization of the Cancer Stem cells (CSCs): one question, many answers Author(s): S Saada Published in: 2018 Workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Bangor University Dielectric characterization of brain cancer cell lines Author(s): W Gamal Published in: 2018 Workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Bangor University Strategy for brain stem cell sorting with SDFF Author(s): G. Begaud; B. Bessette; S. Saad; R. Manczak; M. Mancuso; F. Lalloue; C. Dalmay; A Pothier; P.J.P. Cardot; S. Battu Published in: 2018 International Symposium on Field and Flow Based Separations, 2018 Publisher: ISFFS Novel and versatile instrumentation for electro-manipulation of cancer stem cells Author(s): I. Davies; C. Merla; A. Zambotti; A. Casciati; M. Tanori; J. Bishop; C. Palego; M. Mancuso; C. Hancock Published in: 2018 BioEM 2018 The Joint Annual Meeting of The Bioelectromagnetics Society and the European BioElectromagnetics Association, 2018 Publisher: BioEM DOI: 10.5281/zenodo.2529512 Detection and Neutralization of Cancerous Stem Cells with lab on chip Author(s): A. Pothier Published in: 2018 Workshop of GDR Happybio 06-08 November 201, 2018 Publisher: GDR Happybio Glioblastoma Cancer Stem like Cells discrimination by UHF-Dielectrophoresis Crossover Frequency Author(s): S. Saada , R. Manczak, B. Bessette, G.Begaud, C. Dalmay, S. Battu,P.Blondy, M. Inac, C. Baristiran Kaynak, M. Kaynak, C.Palego, M.0 Jauberteau, A. Pothier, F.Lalloue Published in: 2018 Workshop of French Canceropole GSO, 2018 Publisher: Canceropole GSO Tiny chips: from bee wearable electronics to cancer stem cells seek and destroy Author(s): C. Palego Published in: 2018 Center for High Frequency Electronics Seminar, 2018 Publisher: Cardiff University Discrimination of Glioblastoma Cancer Stem Cells by their UHF-Dielectrophoresis Crossover Frequency Author(s): S. Saada , R. Manczak, B. Bessette, G.Begaud, C. Dalmay, S. Battu,P.Blondy, M. Inac, C. Baristiran Kaynak, M. Kaynak, C.Palego, M.0 Jauberteau, A. Pothier, F.Lalloue Published in: 2018 International Conference on Cancer Stem Cells and Oncology Research, 2018 Publisher: ICCS Electro-permeabilization of isolated cancer stem cells with a push-pull configuration of high power MOSFETs Author(s): I. Davies Published in: 2018 Sumcastec workshop on EM field interaction with biological tissues for cancer and regenerative medicine, 2018 Publisher: Bangor University Highly Sensitive Capacitive Sensor Based on Injection Locked Oscillators with ppm Sensing Resolution Author(s): Meissa Babay, Clement Hallepee, Claire Dalmay, Bruno Barelaud, Emre Can Durmaz, Canan Baristiran Kaynak, Mehmet Kaynak, David Cordeau, Arnaud Pothier Published in: 2020 IEEE/MTT-S International Microwave Symposium (IMS), 2020, Page(s) 456-459, ISBN 978-1-7281-6815-9 Publisher: IEEE DOI: 10.1109/ims30576.2020.9223884 Ultrashort electric pulses: a way to sensitize cancer stem cells Author(s): M. Tanori, C. Casciati, P. Giardullo, B. Benassi, B. Tanno, A. Zambotti, R. Pinto, I. Davis, C. Palego, C. Hancook, C. Marino, M. Mancuso, C. Merla Published in: 2019 SUMCASTEC Biomedical Applications of Electromagnetic Energy Workshop, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.4707045 Ultrashort electric pulses: an effective way to target cancer stem cells Author(s): M. Tanori, C. Casciati, P. Giardullo, B. Tanno, A. Zambotti, B. Benassi, R. Pinto, I. W. Davis, C. Palego, C. Hancok, C. Marino, M. Mancuso and C. Merla Published in: 2021 URSI GASS, 2021 Publisher: URSI DOI: 10.5281/zenodo.4707081 New Generation of Microwave Lab-on-Chip for Cancer Stem Cells Neutralization using Electromagnetic Waves Stimulation Author(s): Saada S., Bessette B, Manczak R, Begaud G, Dalmay C, Battu S, Blondy P, Inac M, Baristiran Kaynak C, Kaynak M, Palego C, Jauberteau MO, Pothier A and Lalloué F Published in: 2017 RoadShow Cancer, 2017 Publisher: zenodo Ultrashort pulsed electric fields as specific radiosensitizer of medulloblastoma cancer stem cells Author(s): M. Tanori, C. Casciati, P. Giardullo, B. Benassi, B. Tanno, A. Zambotti, R. Pinto, C. Marino, M. Mancuso, C. Merla Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4707461 SUMCASTEC: Track, target and neutralize cancer stem cells in solid tumors using micro and nano technologies and electromagnetic waves Author(s): Arnaud Pothier Published in: 2017 Roawshow cancer, 2017 Publisher: zenodo Generating Bipolar nsPulsed Electric Field using Transmission Line & Avalanche Transistors Author(s): Ilan W. Davies, Chris P. Hancock Published in: 2020 50th European Microwave Conference (EuMC), 2021, Page(s) 1003-1006, ISBN 978-2-87487-059-0 Publisher: IEEE DOI: 10.23919/eumc48046.2021.9338198 Targeting in vitro 3D models of glioblastoma with sinusoidal EM fields Author(s): Elena Rampazzo, Luca Persano, Caterina Merla, Arianna Casciati, Mirella Tanori, Mariateresa Mancuso, Christopher Hancock, George Hodgkins, Ilan W. Davis, Cristiano Palego, Nissar Karim, Alice Cani, Silvia Bresolin & Giampietro Viola Published in: 2020 BIOEM Conference, 2020 Publisher: Bioelectromagnetics Society DOI: 10.5281/zenodo.4707146 Potentialités d’architectures de biocapteurs basées sur des oscillateurs hyperfréquences verrouillés par injection Author(s): M. Babay, C. Dalmay, B. Barelaud, M. Kaynak, E. Can Durmaz, C. Baristiran Kaynak D.Cordeau, A. Pothier Published in: 2019 JNM conference, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.2652695 New Method for Detection and Neutralization of Cancer Stem Cells (CSCs) in Brain Tumors Using Electromagnetic Signatures Author(s): Saada S., Bessette B, Manczak R, Begaud G, Dalmay C, Battu S, Blondy P, Inac M, Baristiran Kaynak C, Kaynak M, Palego C, Jauberteau MO, Pothier A and Lalloué F Published in: 2019 Assemblée Générale Ligue contre le cancer Régional, 2019 Publisher: zenodo Cytomètre électromagnétique pour tri continu de cellules biologiques basé sur l’effet de forces diélectrophoretiques hautes fréquences Author(s): T. Provent, R. Manczak, S. Saada, C.Dalmay, B. Bessette, P. Blondy, G. Begaud, S. Battu, M.O. Jauberteau, F. Lalloué, A. Pothier Published in: 2019 JNM conference, 2019 Publisher: Zenodo DOI: 10.5281/zenodo.2652699 Strategy for Brain Cancer Stem Cell sorting with SdFFF. Routine BTSC subpopulations preparation for biosensor calibration Author(s): Bégaud, G., Bessette, B., Saada, S., Manczak, R.,Mancuso, M., Lalloué, F., Dalmay, C., Pothier, A., Cardot, P.J.P., Battu, S., S. Saada, R. Manczak, B. Bessette, L Persano, E Porcù, G. Begaud, C. Dalmay, S Battu, P. Blondy, C. Baristiran Kaynak, M. Kaynak, C. Palego, G Viola, M.O. Jauberteau, A. Pothier, F. Lalloué Published in: 2018 19th International Symposium on Field- and Flow-Based Separation, 2018 Publisher: zenodo Discrimination of Glioblastoma Cancer Stem Cells by their UHF-Dielectrophoresis Crossover Frequency Author(s): S. Saada, R. Manczak, B. Bessette , C. Dalmay, G. Begaud, S. Battu, P. Blondy, M.O. Jauberteau, M. Inac, C. Baristiran Kaynak, M. Kaynak, C. Palego, A. Pothier and F. Lalloue Published in: 2018 11th International Conference on Cancer Stem Cells and Oncology Research, 2018 Publisher: zenodo Micro-Pulse Electric Fields exposure targeting medulloblastoma cancer stem cells Author(s): M. Tanori; A. Casciati; B. Tanno; P. Giardullo; A. Zambotti; C. Marino; C. Merla; M. Mancuso Published in: 2019 3rd SUNRISE Meeting on New Advances in Cancer Stem Cells, 2019 Publisher: zenodo DOI: 10.5281/zenodo.3602738 A High Frequency Dielectrophoresis Cytometer for Continuous Flow Biological Cells Refinement Author(s): Thomas Provent, Audrey Mauvy, Remi Manczak, Sofiane Saada, Claire Dalmay, Barbara Bessette, Fabrice Lalloue, Arnaud Pothier Published in: 2020 50th European Microwave Conference (EuMC), 2021, Page(s) 921-924, ISBN 978-2-87487-059-0 Publisher: IEEE DOI: 10.23919/eumc48046.2021.9338228 Other (1) Discrimination and Neutralization of Cancer Stem-like Cells (CSCs) (Glioblastoma) Author(s): Saada S., Bessette B, Manczak R, Begaud G, Dalmay C, Battu S, Blondy P, Inac M, Baristiran Kaynak C, Kaynak M, Palego C, Jauberteau MO, Pothier A and Lalloué F Published in: 2019 Annual day GEIST, 2019 Publisher: zenodo Intellectual Property Rights Patent (2) Electrosurgical Generator Application/Publication number: GB 1805124.3 Date: 2018-03-29 Applicant(s): CREO MEDICAL LIMITED Electrosurgical Generator Application/Publication number: GB 1805124.3 Date: 2018-03-29 Applicant(s): CREO MEDICAL LIMITED Searching for OpenAIRE data... 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