Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology

Project Information

ACETOGENS

Grant agreement ID: 741791

DOI

10.3030/741791

Project closed

EC signature date 10 May 2017

Start date 1 October 2017

End date 30 September 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 497 140,00

EU contribution

€ 2 497 140,00

Coordinated by

JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (37)

Biologische Wasserstoffspeicherung: HDCR-katalysierte Hydrogenierung von CO2 zum H2-Carrier Ameisensäure

Author(s): Volker Müller, Yvonne Burger
Published in: BIOspektrum, 2022, ISSN 0947-0867
Publisher: Spektrum Akademischer Verlag GmbH
DOI: 10.1007/s12268-022-1854-y

One substrate, many fates: different ways of methanol utilization in the acetogen Acetobacterium woodii

Author(s): Dennis Litty, Florian Kremp, Volker Müller
Published in: Environmental Microbiology, 2022, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16011

Acetogenic Conversion of H2 and CO2 into Formic Acid and Vice Versa in a Fed-Batch-Operated Stirred-Tank Bioreactor

Author(s): Fabian M. Schwarz, Florian Oswald, Volker Müller
Published in: ACS Sustainable Chem. Eng., 2021, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.1c01062

Energy conservation in the acetogenic bacterium Clostridium aceticum

Author(s): Anja Wiechmann, Volker Müller
Published in: Microorganisms, 2021, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms9020258

Lactate formation from fructose or C1 compounds in the acetogen Acetobacterium woodii by metabolic engineering

Author(s): Jimyung Moon; Lara M. Waschinger; Volker Müller
Published in: Applied Microbiology and Biotechnology, Issue 107, 2023, Page(s) 5491-5502, ISSN 0175-7598
Publisher: Springer Verlag
DOI: 10.1007/s00253-023-12637-7

Molecular architecture and electron transfer pathway of the Stn family transhydrogenase

Author(s): Anuj Kumar, Florian Kremp, Jennifer Roth, Sven A. Freibert, Volker Müller, Jan M. Schuller
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-41212-x

Physiology and genetics of ethanologenesis in the acetogenic bacterium Acetobacterium woodii

Author(s): Jimyung Moon, Volker Müller
Published in: Environmental Microbiology, Issue 23, 2021, Page(s) 6953-6964, ISSN 1758-2229
Publisher: Wiley-Blackwell
DOI: 10.1111/1462-2920.15739

A new metabolic trait in an acetogen: Mixed acid fermentation of fructose in a methylene‐tetrahydrofolate reductase mutant of <i>Acetobacterium woodii</i>

Author(s): Jimyung Moon; Anja Schubert; Anja Poehlein; Rolf Daniel; Volker Müller
Published in: Environmental Microbiology Reports, Issue 15, 2023, ISSN 1758-2229
Publisher: Wiley-Blackwell
DOI: 10.1111/1758-2229.13160

Formate-driven H2 production by whole cells of Thermoanaerobacter kivui

Author(s): Yvonne Burger, Fabian M. Schwarz, Volker Müller 
Published in: Biotechnology for Biofuels and Bioproducts, 2022, ISSN 2731-3654
Publisher: BMC
DOI: 10.1186/s13068-022-02147-5

Biosynthesis of butyrate from methanol and carbon monoxideby recombinant Acetobacterium woodi

Author(s): Nilanjan Pal Chowdhury, Dennis Litty, Volker Müller
Published in: International Microbiology, 2022, ISSN 1139-6709
Publisher: Sociedad Espanola de Microbiologia
DOI: 10.1007/s10123-022-00234-z

Exploring Bacterial Microcompartments in the Acetogenic Bacterium Acetobacterium woodii

Author(s): Nilanjan Pal Chowdhury, Lydia Alberti, Mark Linder and Volker Müller
Published in: Frontiers in Microbiology, 2020, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.593467

Adh4, an alcohol dehydrogenase controls alcohol formation within bacterial mircrocompartments in the acetogenic bacterium Acetobacterium woodii

Author(s): Nilanjan Pal Chowdhury, Jimyung Moon, Volker Müller
Published in: Environmental Microbiology, 2020, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15340

Membrane-anchored HDCR nanowires drive hydrogen-dependent CO2 fixation

Author(s): Helge M. Dietrich, Ricardo D. Righetto, Anuj Kumar, Wojciech Wietrzynski, Raphael Trischler, Sandra K. Schuller, Jonathan Wagner, Fabian M. Schwarz, Benjamin D. Engel, Volker Müller, Jan M. Schuller
Published in: Nature, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04971-z

Revealing formate production from carbon monoxide in wild type and mutants of Rnf- and Ech-containing acetogens, Acetobacterium woodii and Thermoanaerobacter kivui

Author(s): Fabian M. Schwarz, Sarah Ciurus, Surbhi Jain, Christoph Baum, Anja Wiechmann, Mirko Basen, Volker Müller
Published in: Microbial biotechnology, 2020, ISSN 1751-7907
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1751-7915.13663

Growth of the acetogenic bacterium Acetobacterium woodii on glycerol and dihydroxyacetone

Author(s): Dragan Trifunović, Jimyung Moon, Anja Poehlein, Rolf Daniel, Volker Müller
Published in: Environmental Microbiology, 2021, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15503

A third way of energy conservation in acetogenic bacteria

Author(s): Florian Kremp, Jennifer Roth, Volker Müller 
Published in: Microbiology Spectrum, 2022, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.01385-22

Reprogramming the metabolism of an acetogenic bacterium to homoformatogenesis

Author(s): Jimyung Moon, Anja Schubert, Lara M. Waschinger, Volker Müller
Published in: The ISME Journal, 2023, ISSN 1751-7362
Publisher: Nature Publishing Group
DOI: 10.1038/s41396-023-01411-2

Methanol and methyl group conversion in acetogenic bacteria: Biochemistry, physiology and application

Author(s): Florian Kremp, Volker Müller
Published in: FEMS Microbiology Reviews, 2020, ISSN 0168-6445
Publisher: Blackwell
DOI: 10.1093/femsre/fuaa040

A synthetic bacterial microcompartment as production platform for pyruvate from formate and acetate

Author(s): Volker Müller
Published in: PNAS, 2022, ISSN 1091-6490
Publisher: National Academy of Science
DOI: 10.1073/pnas.2201330119

The Sporomusa type Nfn is a novel type of electron-bifurcating transhydrogenase that links the redox pools in acetogenic bacteria

Author(s): Florian Kremp, jennifer Roth, Volker Müller
Published in: Scientific reports, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-71038-2

Biological hydrogen storage and release through multiple cycles of bi-directional hydrogenation of CO2 to formic acid in a single process unit

Author(s): Fabian M. Schwarz, Jimyung Moon, Florian Oswald, Volker Müller
Published in: Joule, 2022, ISSN 2542-4785
Publisher: Elsevier Inc.
DOI: 10.1016/j.joule.2022.04.020

Efficient whole cell biocatalyst for formate-based hydrogen production

Author(s): Patrick Kottenhahn, Kai Schuchmann, Volker Müller
Published in: Biotechnology for Biofuels, Issue 11/1, 2018, ISSN 1754-6834
Publisher: Springer Nature
DOI: 10.1186/s13068-018-1082-3

Complex Multimeric [FeFe] Hydrogenases: Biochemistry, Physiology and New Opportunities for the Hydrogen Economy

Author(s): Kai Schuchmann, Nilanjan Pal Chowdhury, Volker Müller
Published in: Frontiers in Microbiology, Issue 9, 2018, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2018.02911

Hydrogenation of CO2 at ambient pressure catalyzed by a highly active thermostable biocatalyst

Author(s): Fabian M. Schwarz, Kai Schuchmann, Volker Müller
Published in: Biotechnology for Biofuels, Issue 11/1, 2018, ISSN 1754-6834
Publisher: Springer Nature
DOI: 10.1186/s13068-018-1236-3

Whole-cell biocatalysis for hydrogen storage and syngas conversion to formate using a thermophilic acetogen

Author(s): Fabian M. Schwarz, Volker Müller
Published in: Biotechnology for Biofuels, Issue 13/1, 2020, ISSN 1754-6834
Publisher: BioMed Central Ltd / Springer Nature
DOI: 10.1186/s13068-020-1670-x

Alanine, a Novel Growth Substrate for the Acetogenic Bacterium Acetobacterium woodii

Author(s): Judith Dönig, Volker Müller
Published in: Applied and Environmental Microbiology, Issue 84/23, 2018, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/aem.02023-18

It does not always take two to tango: “Syntrophy” via hydrogen cycling in one bacterial cell

Author(s): Anja Wiechmann, Sarah Ciurus, Florian Oswald, Vinca N. Seiler, Volker Müller
Published in: The ISME Journal, Issue 14/6, 2020, Page(s) 1561-1570, ISSN 1751-7362
Publisher: Nature Publishing Group
DOI: 10.1038/s41396-020-0627-1

Formate Is Required for Growth of the Thermophilic Acetogenic Bacterium Thermoanaerobacter kivui Lacking Hydrogen-Dependent Carbon Dioxide Reductase (HDCR)

Author(s): Surbhi Jain, Helge M. Dietrich, Volker Müller, Mirko Basen
Published in: Frontiers in Microbiology, Issue 11, 2020, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2020.00059

Methanol metabolism in the acetogenic bacterium Acetobacterium woodii

Author(s): Florian Kremp, Anja Poehlein, Rolf Daniel, Volker Müller
Published in: Environmental Microbiology, Issue 20/12, 2018, Page(s) 4369-4384, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.14356

Glycine betaine metabolism in the acetogenic bacterium Acetobacterium woodii

Author(s): Mats Lechtenfeld, Julia Heine, Janin Sameith, Florian Kremp, Volker Müller
Published in: Environmental Microbiology, Issue 20/12, 2018, Page(s) 4512-4525, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.14389

The monofunctional CO dehydrogenase CooS is essential for growth of Thermoanaerobacter kivui on carbon monoxide

Author(s): Surbhi Jain, Alexander Katsyv, Mirko Basen, Volker Müller 
Published in: Extremophiles, 2022, ISSN 1431-0651
Publisher: Springer Verlag
DOI: 10.1007/s00792-021-01251-y

Enzymatic Hydrogen Electrosynthesis at Enhanced Current Density Using a Redox Polymer

Author(s): John C. Ruth, Fabian M. Schwarz, Volker Müller, Alfred M. Spormann
Published in: Catalysts, 2021, ISSN 2073-4344
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal11101197

Formate metabolism in the acetogenic bacterium Acetobacterium woodii

Author(s): Jimyung Moon, Judith Dönig, Sina Kramer, Anja Poehlein, Rolf Daniel, Volker Müller
Published in: Environmental Microbiology, 2021, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15598

Genome-scale analysis of Acetobacterium woodii identifies translational regulation of acetogenesis

Author(s): Jongoh Shin, Yoseb Song, Seulgi Kang, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Suhyung Cho, Volker Müller, Byung-Kwan Cho
Published in: mSystems, 2021, ISSN 2379-5077
Publisher: American Society for Microbiology
DOI: 10.1128/msystems.00696-21

Ethanologenesis from glycerol by the gut acetogen Blautia schinkii

Author(s): Raphael Trischler, Anja Poehlein, Rolf Daniel, Volker Müller
Published in: Environmental Microbiology, 2023, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16517

Capture of carbon dioxide and hydrogen by engineeredEscherichia coli: hydrogen-dependent CO2 reduction to formate

Author(s): Felix Leo, Fabian M. Schwarz, Kai Schuchmann, Volker Müller
Published in: Applied Microbiology and Biotechnology, 2021, ISSN 0175-7598
Publisher: Springer Verlag
DOI: 10.1007/s00253-021-11463-z

A functional <scp>Wood–Ljungdahl</scp> pathway devoid of a formate dehydrogenase in the gut acetogens <i>Blautia wexlerae</i>, <i>Blautia luti</i> and beyond

Author(s): Raphael Trischler; Jennifer Roth; Matthew T. Sorbara; Xenia Schlegel; Volker Müller
Published in: Environmental Microbiology, Issue 24, 2022, Page(s) 3111-3123, ISSN 1462-2912
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16029