Acetogenic bacteria: from basic physiology via gene regulation to application in industrial biotechnology

Informazioni relative al progetto

ACETOGENS

ID dell’accordo di sovvenzione: 741791

DOI 10.3030/741791

Progetto chiuso

Data della firma CE 10 Maggio 2017

Data di avvio 1 Ottobre 2017

Data di completamento 30 Settembre 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 497 140,00

Contributo UE € 2 497 140,00

Coordinato da

JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany

Pubblicazioni

Peer reviewed articles (37)

Biologische Wasserstoffspeicherung: HDCR-katalysierte Hydrogenierung von CO2 zum H2-Carrier Ameisensäure

Autori: Volker Müller, Yvonne Burger
Pubblicato in: BIOspektrum, 2022, ISSN 0947-0867
Editore: Spektrum Akademischer Verlag GmbH
DOI: 10.1007/s12268-022-1854-y

One substrate, many fates: different ways of methanol utilization in the acetogen Acetobacterium woodii

Autori: Dennis Litty, Florian Kremp, Volker Müller
Pubblicato in: Environmental Microbiology, 2022, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16011

Acetogenic Conversion of H2 and CO2 into Formic Acid and Vice Versa in a Fed-Batch-Operated Stirred-Tank Bioreactor

Autori: Fabian M. Schwarz, Florian Oswald, Volker Müller
Pubblicato in: ACS Sustainable Chem. Eng., 2021, ISSN 2168-0485
Editore: American Chemical Society
DOI: 10.1021/acssuschemeng.1c01062

Energy conservation in the acetogenic bacterium Clostridium aceticum

Autori: Anja Wiechmann, Volker Müller
Pubblicato in: Microorganisms, 2021, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms9020258

Lactate formation from fructose or C1 compounds in the acetogen Acetobacterium woodii by metabolic engineering

Autori: Jimyung Moon; Lara M. Waschinger; Volker Müller
Pubblicato in: Applied Microbiology and Biotechnology, Numero 107, 2023, Pagina/e 5491-5502, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-023-12637-7

Molecular architecture and electron transfer pathway of the Stn family transhydrogenase

Autori: Anuj Kumar, Florian Kremp, Jennifer Roth, Sven A. Freibert, Volker Müller, Jan M. Schuller
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-41212-x

Physiology and genetics of ethanologenesis in the acetogenic bacterium Acetobacterium woodii

Autori: Jimyung Moon, Volker Müller
Pubblicato in: Environmental Microbiology, Numero 23, 2021, Pagina/e 6953-6964, ISSN 1758-2229
Editore: Wiley-Blackwell
DOI: 10.1111/1462-2920.15739

A new metabolic trait in an acetogen: Mixed acid fermentation of fructose in a methylene‐tetrahydrofolate reductase mutant of <i>Acetobacterium woodii</i>

Autori: Jimyung Moon; Anja Schubert; Anja Poehlein; Rolf Daniel; Volker Müller
Pubblicato in: Environmental Microbiology Reports, Numero 15, 2023, ISSN 1758-2229
Editore: Wiley-Blackwell
DOI: 10.1111/1758-2229.13160

Formate-driven H2 production by whole cells of Thermoanaerobacter kivui

Autori: Yvonne Burger, Fabian M. Schwarz, Volker Müller 
Pubblicato in: Biotechnology for Biofuels and Bioproducts, 2022, ISSN 2731-3654
Editore: BMC
DOI: 10.1186/s13068-022-02147-5

Biosynthesis of butyrate from methanol and carbon monoxideby recombinant Acetobacterium woodi

Autori: Nilanjan Pal Chowdhury, Dennis Litty, Volker Müller
Pubblicato in: International Microbiology, 2022, ISSN 1139-6709
Editore: Sociedad Espanola de Microbiologia
DOI: 10.1007/s10123-022-00234-z

Exploring Bacterial Microcompartments in the Acetogenic Bacterium Acetobacterium woodii

Autori: Nilanjan Pal Chowdhury, Lydia Alberti, Mark Linder and Volker Müller
Pubblicato in: Frontiers in Microbiology, 2020, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2020.593467

Adh4, an alcohol dehydrogenase controls alcohol formation within bacterial mircrocompartments in the acetogenic bacterium Acetobacterium woodii

Autori: Nilanjan Pal Chowdhury, Jimyung Moon, Volker Müller
Pubblicato in: Environmental Microbiology, 2020, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15340

Membrane-anchored HDCR nanowires drive hydrogen-dependent CO2 fixation

Autori: Helge M. Dietrich, Ricardo D. Righetto, Anuj Kumar, Wojciech Wietrzynski, Raphael Trischler, Sandra K. Schuller, Jonathan Wagner, Fabian M. Schwarz, Benjamin D. Engel, Volker Müller, Jan M. Schuller
Pubblicato in: Nature, 2022, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-022-04971-z

Revealing formate production from carbon monoxide in wild type and mutants of Rnf- and Ech-containing acetogens, Acetobacterium woodii and Thermoanaerobacter kivui

Autori: Fabian M. Schwarz, Sarah Ciurus, Surbhi Jain, Christoph Baum, Anja Wiechmann, Mirko Basen, Volker Müller
Pubblicato in: Microbial biotechnology, 2020, ISSN 1751-7907
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1751-7915.13663

Growth of the acetogenic bacterium Acetobacterium woodii on glycerol and dihydroxyacetone

Autori: Dragan Trifunović, Jimyung Moon, Anja Poehlein, Rolf Daniel, Volker Müller
Pubblicato in: Environmental Microbiology, 2021, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15503

A third way of energy conservation in acetogenic bacteria

Autori: Florian Kremp, Jennifer Roth, Volker Müller 
Pubblicato in: Microbiology Spectrum, 2022, ISSN 2165-0497
Editore: American Society for Microbiology
DOI: 10.1128/spectrum.01385-22

Reprogramming the metabolism of an acetogenic bacterium to homoformatogenesis

Autori: Jimyung Moon, Anja Schubert, Lara M. Waschinger, Volker Müller
Pubblicato in: The ISME Journal, 2023, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-023-01411-2

Methanol and methyl group conversion in acetogenic bacteria: Biochemistry, physiology and application

Autori: Florian Kremp, Volker Müller
Pubblicato in: FEMS Microbiology Reviews, 2020, ISSN 0168-6445
Editore: Blackwell
DOI: 10.1093/femsre/fuaa040

A synthetic bacterial microcompartment as production platform for pyruvate from formate and acetate

Autori: Volker Müller
Pubblicato in: PNAS, 2022, ISSN 1091-6490
Editore: National Academy of Science
DOI: 10.1073/pnas.2201330119

The Sporomusa type Nfn is a novel type of electron-bifurcating transhydrogenase that links the redox pools in acetogenic bacteria

Autori: Florian Kremp, jennifer Roth, Volker Müller
Pubblicato in: Scientific reports, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-71038-2

Biological hydrogen storage and release through multiple cycles of bi-directional hydrogenation of CO2 to formic acid in a single process unit

Autori: Fabian M. Schwarz, Jimyung Moon, Florian Oswald, Volker Müller
Pubblicato in: Joule, 2022, ISSN 2542-4785
Editore: Elsevier Inc.
DOI: 10.1016/j.joule.2022.04.020

Efficient whole cell biocatalyst for formate-based hydrogen production

Autori: Patrick Kottenhahn, Kai Schuchmann, Volker Müller
Pubblicato in: Biotechnology for Biofuels, Numero 11/1, 2018, ISSN 1754-6834
Editore: Springer Nature
DOI: 10.1186/s13068-018-1082-3

Complex Multimeric [FeFe] Hydrogenases: Biochemistry, Physiology and New Opportunities for the Hydrogen Economy

Autori: Kai Schuchmann, Nilanjan Pal Chowdhury, Volker Müller
Pubblicato in: Frontiers in Microbiology, Numero 9, 2018, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2018.02911

Hydrogenation of CO2 at ambient pressure catalyzed by a highly active thermostable biocatalyst

Autori: Fabian M. Schwarz, Kai Schuchmann, Volker Müller
Pubblicato in: Biotechnology for Biofuels, Numero 11/1, 2018, ISSN 1754-6834
Editore: Springer Nature
DOI: 10.1186/s13068-018-1236-3

Whole-cell biocatalysis for hydrogen storage and syngas conversion to formate using a thermophilic acetogen

Autori: Fabian M. Schwarz, Volker Müller
Pubblicato in: Biotechnology for Biofuels, Numero 13/1, 2020, ISSN 1754-6834
Editore: BioMed Central Ltd / Springer Nature
DOI: 10.1186/s13068-020-1670-x

Alanine, a Novel Growth Substrate for the Acetogenic Bacterium Acetobacterium woodii

Autori: Judith Dönig, Volker Müller
Pubblicato in: Applied and Environmental Microbiology, Numero 84/23, 2018, ISSN 0099-2240
Editore: American Society for Microbiology
DOI: 10.1128/aem.02023-18

It does not always take two to tango: “Syntrophy” via hydrogen cycling in one bacterial cell

Autori: Anja Wiechmann, Sarah Ciurus, Florian Oswald, Vinca N. Seiler, Volker Müller
Pubblicato in: The ISME Journal, Numero 14/6, 2020, Pagina/e 1561-1570, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-020-0627-1

Formate Is Required for Growth of the Thermophilic Acetogenic Bacterium Thermoanaerobacter kivui Lacking Hydrogen-Dependent Carbon Dioxide Reductase (HDCR)

Autori: Surbhi Jain, Helge M. Dietrich, Volker Müller, Mirko Basen
Pubblicato in: Frontiers in Microbiology, Numero 11, 2020, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2020.00059

Methanol metabolism in the acetogenic bacterium Acetobacterium woodii

Autori: Florian Kremp, Anja Poehlein, Rolf Daniel, Volker Müller
Pubblicato in: Environmental Microbiology, Numero 20/12, 2018, Pagina/e 4369-4384, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.14356

Glycine betaine metabolism in the acetogenic bacterium Acetobacterium woodii

Autori: Mats Lechtenfeld, Julia Heine, Janin Sameith, Florian Kremp, Volker Müller
Pubblicato in: Environmental Microbiology, Numero 20/12, 2018, Pagina/e 4512-4525, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.14389

The monofunctional CO dehydrogenase CooS is essential for growth of Thermoanaerobacter kivui on carbon monoxide

Autori: Surbhi Jain, Alexander Katsyv, Mirko Basen, Volker Müller 
Pubblicato in: Extremophiles, 2022, ISSN 1431-0651
Editore: Springer Verlag
DOI: 10.1007/s00792-021-01251-y

Enzymatic Hydrogen Electrosynthesis at Enhanced Current Density Using a Redox Polymer

Autori: John C. Ruth, Fabian M. Schwarz, Volker Müller, Alfred M. Spormann
Pubblicato in: Catalysts, 2021, ISSN 2073-4344
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal11101197

Formate metabolism in the acetogenic bacterium Acetobacterium woodii

Autori: Jimyung Moon, Judith Dönig, Sina Kramer, Anja Poehlein, Rolf Daniel, Volker Müller
Pubblicato in: Environmental Microbiology, 2021, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.15598

Genome-scale analysis of Acetobacterium woodii identifies translational regulation of acetogenesis

Autori: Jongoh Shin, Yoseb Song, Seulgi Kang, Sangrak Jin, Jung-Kul Lee, Dong Rip Kim, Suhyung Cho, Volker Müller, Byung-Kwan Cho
Pubblicato in: mSystems, 2021, ISSN 2379-5077
Editore: American Society for Microbiology
DOI: 10.1128/msystems.00696-21

Ethanologenesis from glycerol by the gut acetogen Blautia schinkii

Autori: Raphael Trischler, Anja Poehlein, Rolf Daniel, Volker Müller
Pubblicato in: Environmental Microbiology, 2023, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16517

Capture of carbon dioxide and hydrogen by engineeredEscherichia coli: hydrogen-dependent CO2 reduction to formate

Autori: Felix Leo, Fabian M. Schwarz, Kai Schuchmann, Volker Müller
Pubblicato in: Applied Microbiology and Biotechnology, 2021, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-021-11463-z

A functional <scp>Wood–Ljungdahl</scp> pathway devoid of a formate dehydrogenase in the gut acetogens <i>Blautia wexlerae</i>, <i>Blautia luti</i> and beyond

Autori: Raphael Trischler; Jennifer Roth; Matthew T. Sorbara; Xenia Schlegel; Volker Müller
Pubblicato in: Environmental Microbiology, Numero 24, 2022, Pagina/e 3111-3123, ISSN 1462-2912
Editore: Blackwell Publishing Inc.
DOI: 10.1111/1462-2920.16029