HD-DittoGraph: a digital human Embryonic Stem Cell platform for Huntington's repeats

Project Information

HD-DittoGraph

Grant agreement ID: 742436

DOI

10.3030/742436

Project closed

EC signature date 29 November 2017

Start date 1 March 2018

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 040 943,00

EU contribution

€ 2 040 943,00

Coordinated by

UNIVERSITA DEGLI STUDI DI MILANO
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (2)

When repetita no-longer iuvant: somatic instability of the CAG triplet in Huntington’s disease

Author(s): Elena Cattaneo, Davide Scalzo, Martina Zobel, Raffaele Iennaco, Camilla Maffezzini, Dario Besusso, Simone Maestri
Published in: Nucleic Acids Research, Issue 53, 2025, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkae1204

Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids

Author(s): Maura Galimberti, Maria R. Nucera, Vittoria D. Bocchi, Paola Conforti, Elena Vezzoli, Matteo Cereda, Camilla Maffezzini, Raffaele Iennaco, Andrea Scolz, Andrea Falqui, Chiara Cordiglieri, Martina Cremona, Ira Espuny-Camacho, Andrea Faedo, Dan P. Felsenfeld, Thomas F. Vogt, Valeria Ranzani, Chiara Zuccato, Dario Besusso, Elena Cattaneo
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-50877-x