Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing

Project Information

SystGeneEdit

Grant agreement ID: 742804

DOI

10.3030/742804

Project closed

EC signature date 16 May 2017

Start date 1 November 2017

End date 31 October 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 995,00

EU contribution

€ 2 499 995,00

Coordinated by

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

CRISPRi screens reveal genes modulating yeast growth in lignocellulose hydrolysate

Author(s): Gutmann F, Jann C, Pereira F, Johansson A, Steinmetz LM, Patil KR
Published in: Biotechnology for Biofuels, 2021, ISSN 2731-3654
Publisher: Springer Nature
DOI: 10.1186/s13068-021-01880-7

High-throughput functional characterization of protein phosphorylation sites in yeast

Author(s): Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P
Published in: Nature Biotechnology, 2022, ISSN 1087-0156
Publisher: Nature Publishing Group
DOI: 10.1038/s41587-021-01051-x

Fast and inexpensive whole genome sequencing library preparation from intact yeast cells

Author(s): Vonesch SC, Li S, Szu Tu C, Hennig BP, Dobrev N, Steinmetz LM
Published in: G3 Genes|Genomes|Genetics, 2020, ISSN 2160-1836
Publisher: Genetics Society of America
DOI: 10.1101/2020.09.03.280990

High-speed fluorescence image-enabled cell sorting

Author(s): Schraivogel D, Kuhn TM, Rauscher B, Rodríguez-Martínez M, Paulsen M, Owsley K, Middlebrook A, Tischer C, Ramasz B, Ordoñez-Rueda D, Dees M, Cuylen-Haering S, Diebold E, Steinmetz LM
Published in: Science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abj3013

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization

Author(s): Chiara Baccin, Jude Al-Sabah, Lars Velten, Patrick M. Helbling, Florian Grünschläger, Pablo Hernández-Malmierca, César Nombela-Arrieta, Lars M. Steinmetz, Andreas Trumpp, Simon Haas
Published in: Nature Cell Biology, Issue 22/1, 2020, Page(s) 38-48, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-019-0439-6

Targeted Perturb-seq enables genome-scale genetic screens in single cells

Author(s): Daniel Schraivogel, Andreas R. Gschwind, Jennifer H. Milbank, Daniel R. Leonce, Petra Jakob, Lukas Mathur, Jan O. Korbel, Christoph A. Merten, Lars Velten, Lars M. Steinmetz
Published in: Nature Methods, Issue 17/6, 2020, Page(s) 629-635, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-020-0837-5

Thesis and dissertations (1)

Mechanisms of Cellular Stress Adaptation

Author(s): Jann, C
Published in: 2020
Publisher: Doctor of Science - ETH Zurich
DOI: 10.3929/ethz-b-000480073

Other (1)

Towards a systematic map of the functional role of protein phosphorylation

Author(s): C. Viéitez, B. P. Busby, D. Ochoa, A. Mateus, M. Galardini, A. Jawed, D. Memon, C. Potel, S. C. Vonesch, C. Szu Tu, M. Shahraz, F. Stein, L. M. Steinmetz, M. Savitski, A. Typas, P. Beltrao
Published in: bioRXiv, 2019
Publisher: bioRXiv
DOI: 10.1101/872770