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Translational implications of the discovery of brain-draining lymphatics

Publications

Development and plasticity of meningeal lymphatic vessels

Author(s): Salli Antila, Sinem Karaman, Harri Nurmi, Mikko Airavaara, Merja H. Voutilainen, Thomas Mathivet, Dmitri Chilov, Zhilin Li, Tapani Koppinen, Jun-Hee Park, Shentong Fang, Aleksanteri Aspelund, Mart Saarma, Anne Eichmann, Jean-Léon Thomas, Kari Alitalo
Published in: The Journal of Experimental Medicine, Issue 214/12, 2017, Page(s) 3645-3667, ISSN 0022-1007
DOI: 10.1084/jem.20170391

Vascular endothelial growth factor signaling in development and disease

Author(s): Sinem Karaman, Veli-Matti Leppänen, Kari Alitalo
Published in: Development, Issue 145/14, 2018, Page(s) dev151019, ISSN 0950-1991
DOI: 10.1242/dev.151019

Understanding the functions and relationships of the glymphatic system and meningeal lymphatics

Author(s): Antoine Louveau, Benjamin A. Plog, Salli Antila, Kari Alitalo, Maiken Nedergaard, Jonathan Kipnis
Published in: Journal of Clinical Investigation, Issue 127/9, 2017, Page(s) 3210-3219, ISSN 0021-9738
DOI: 10.1172/jci90603

Anatomy and function of the vertebral column lymphatic network in mice

Author(s): Laurent Jacob, Ligia Simoes Braga Boisserand, Luiz Henrique Medeiros Geraldo, Jose de Brito Neto, Thomas Mathivet, Salli Antila, Besma Barka, Yunling Xu, Jean-Mickael Thomas, Juliette Pestel, Marie-Stéphane Aigrot, Eric Song, Harri Nurmi, Seyoung Lee, Kari Alitalo, Nicolas Renier, Anne Eichmann, Jean-Leon Thomas
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-12568-w

KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

Author(s): Sawan Kumar Jha, Khushbu Rauniyar, Ewa Chronowska, Kenny Mattonet, Eunice Wairimu Maina, Hannu Koistinen, Ulf-Håkan Stenman, Kari Alitalo, Michael Jeltsch
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
DOI: 10.7554/elife.44478

Cardiac lymphatics in health and disease

Author(s): Ebba Brakenhielm, Kari Alitalo
Published in: Nature Reviews Cardiology, Issue 16/1, 2019, Page(s) 56-68, ISSN 1759-5002
DOI: 10.1038/s41569-018-0087-8

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS

Author(s): Zhilin Li, Emilia A. Korhonen, Arianna Merlini, Judith Strauss, Eleonoora Wihuri, Harri Nurmi, Salli Antila, Jennifer Paech, Urban Deutsch, Britta Engelhardt, Sudhakar Chintharlapalli, Gou Young Koh, Alexander Flügel, Kari Alitalo
Published in: Journal of Clinical Investigation, Issue 130/4, 2020, Page(s) 1977-1990, ISSN 0021-9738
DOI: 10.1172/jci130308

Stimulation and Inhibition of Lymphangiogenesis Via Adeno-Associated Viral Gene Delivery

Author(s): Sinem Karaman, Harri Nurmi, Salli Antila, Kari Alitalo
Published in: Lymphangiogenesis - Methods and Protocols, Issue 1846, 2018, Page(s) 291-300
DOI: 10.1007/978-1-4939-8712-2_19