Microalgae As a Green source for Nutritional Ingredients for Food/Feed and Ingredients for Cosmetics by cost-Effective New Technologies

Project Information

MAGNIFICENT

Grant agreement ID: 745754

DOI 10.3030/745754

Project closed

EC signature date 4 May 2017

Start date 1 June 2017

End date 30 November 2021

Funded under

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Total cost € 5 685 015,41

EU contribution € 5 330 259,16

Coordinated by

WAGENINGEN UNIVERSITY
Netherlands

Deliverables

Documents, reports (8)

Final report on economic feasibility
Scientific publication on the potential of algae-derived PLs and β-glucans in starter feeds for marine fish larvae and juveniles

Scientific publication on the potential of algaederived PLs and glucans in starter feeds for marine fish larvae and juveniles

Agreed initial goal and scope for Techno-economic analysis
Final report on LCA and socio-economic performance

Final report on LCA and socioeconomic performance

Agreed initial goal and scope for LCA
At least one improved strain of Phaeodactylum/Isochrysis with increased fucoxanthin productivity

At least one improved strain of PhaeodactylumIsochrysis with increased fucoxanthin productivity

Harmonised protocols for characterization of algae and extracts compositio

Harmonised protocols for characterization of algae and extracts composition

Agreed initial goal and scope for S-LCA

Websites, patent fillings, videos etc. (4)

Batch of project promotional material
Batch of project promotional material UpdateM54
Project public website
Batch of project promotional material UpdateM36

Other (1)

Identity set

Publications

Peer reviewed articles (18)

Comprehensive Genome Engineering Toolbox for Microalgae Nannochloropsis oceanica Based on CRISPR-Cas Systems

Author(s): Naduthodi, Mihris Ibnu Saleem; Südfeld, Christian; Avitzigiannis, Emmanouil Klimis; Trevisan, Nicola; van Lith, Eduard; Alcaide Sancho, Javier; D'Adamo, Sarah; Barbosa, Maria; van der Oost, John
Published in: ACS Synth. Biol. 2021, 10, 12,, 2021, Page(s) 3369–3378, ISSN 1520-5126
Publisher: American Chemical Society
DOI: 10.1021/acssynbio.1c00329

Fucoxanthin and docosahexaenoic acid production by cold-adapted Tisochrysis lutea

Author(s): Gao, Fengzheng; Dominguez Cabanelas, Iago Teles; Wijffels, René H.; Barbosa, Maria J.
Published in: New Biotechnology Volume 66, 25 January 2022,, 2022, Page(s) Pages 16-24, ISSN 1871-6784
Publisher: Elsevier BV
DOI: 10.1016/j.nbt.2021.08.005

Production and monitoring of biomass and fucoxanthin with brown microalgae under outdoor conditions

Author(s): Fengzheng Gao, Marta Sá, Iago Teles (Cabanelas, ITD), René H. Wijffels, Maria J. Barbosa
Published in: Biotechnology and Bioengineering, Issue 118/3, 2021, Page(s) 1355-1365, ISSN 0006-3592
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27657

Production and high throughput quantification of fucoxanthin and lipids in Tisochrysis lutea using single-cell fluorescence

Author(s): Fengzheng Gao, Iago Teles (Cabanelas, ITD), Narcís Ferrer-Ledo, René H. Wijffels, Maria J. Barbosa
Published in: Bioresource Technology, Issue 318, 2020, Page(s) 124104, ISSN 0960-8524
Publisher: Elsevier BV
DOI: 10.1016/j.biortech.2020.124104

Process optimization of fucoxanthin production with Tisochrysis lutea

Author(s): Fengzheng Gao, Iago Teles (Cabanelas, ITD), René H Wijffels, Maria J Barbosa
Published in: Bioresource Technology, Issue 315, 2020, Page(s) 123894, ISSN 0960-8524
Publisher: Elsevier BV
DOI: 10.1016/j.biortech.2020.123894

Management of Hypercholesterolemia Through Dietary ß-glucans–Insights From a Zebrafish Model

Author(s): Gora, Adnan Hussain; Rehman, Saima; Kiron, Viswanath; Dias, Jorge; Fernandes, Jorge M. O.; Olsvik, Pål Asgeir; Siriyappagouder, Prabhugouda; Vatsos, Ioannis; Schmid-Staiger, Ulrike; Frick, Konstantin; Cardoso, Miguel
Published in: Frontiers in Nutrition, VOLUME 8, 2022, Issue 2, 2022, ISSN 2296-861X
Publisher: Frontiers
DOI: 10.3389/fnut.2021.797452

Progress of CRISPR-Cas Based Genome Editing in Photosynthetic Microbes

Author(s): Mihris Ibnu Saleem Naduthodi, Maria J. Barbosa, John van der Oost
Published in: Biotechnology Journal, Issue 13/9, 2018, Page(s) 1700591, ISSN 1860-6768
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201700591

CRISPR–Cas ribonucleoprotein mediated homology-directed repair for efficient targeted genome editing in microalgae Nannochloropsis oceanica IMET1

Author(s): Mihris Ibnu Saleem Naduthodi, Prarthana Mohanraju, Christian Südfeld, Sarah D’Adamo, Maria J. Barbosa, John van der Oost
Published in: Biotechnology for Biofuels, Issue 12/1, 2019, ISSN 1754-6834
Publisher: BMC
DOI: 10.1186/s13068-019-1401-3

Monitoring of eicosapentaenoic acid (EPA) production in the microalgae Nannochloropsis oceanica

Author(s): Marta Sá, Narcís Ferrer-Ledo, Rene Wijffels, João G. Crespo, Maria Barbosa, Claudia F. Galinha
Published in: Algal Research, Issue 45, 2020, Page(s) 101766, ISSN 2211-9264
Publisher: Elsevier BV
DOI: 10.1016/j.algal.2019.101766

Fluorescence spectroscopy and chemometrics for simultaneous monitoring of cell concentration, chlorophyll and fatty acids in Nannochloropsis oceanica

Author(s): Marta Sá, Carlo G. Bertinetto, Narcís Ferrer-Ledo, Jeroen J. Jansen, Rene Wijffels, João G. Crespo, Maria Barbosa, Claudia F. Galinha
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-64628-7

Fucoxanthin, A Carotenoid Derived from Phaeodactylum tricornutum Exerts Antiproliferative and Antioxidant Activities In Vitro

Author(s): Ulrike Neumann, Felix Derwenskus, Verena Flaiz Flister, Ulrike Schmid-Staiger, Thomas Hirth, Stephan Bischoff
Published in: Antioxidants, Issue 8/6, 2019, Page(s) 183, ISSN 2076-3921
Publisher: MDPI
DOI: 10.3390/antiox8060183

Pressurized extraction of unsaturated fatty acids and carotenoids from wet Chlorella vulgaris and Phaeodactylum tricornutum biomass using subcritical liquids

Author(s): Felix Derwenskus, Felix Metz, Andrea Gille, Ulrike Schmid-Staiger, Karlis Briviba, Ursula Schließmann, Thomas Hirth
Published in: GCB Bioenergy, Issue 11/1, 2019, Page(s) 335-344, ISSN 1757-1693
Publisher: Wiley-VCH Verlag
DOI: 10.1111/gcbb.12563

A Lipophilic Fucoxanthin-Rich Phaeodactylum tricornutum Extract Ameliorates Effects of Diet-Induced Obesity in C57BL/6J Mice

Author(s): Andrea Gille, Bojan Stojnic, Felix Derwenskus, Andreas Trautmann, Ulrike Schmid-Staiger, Clemens Posten, Karlis Briviba, Andreu Palou, M. Bonet, Joan Ribot
Published in: Nutrients, Issue 11/4, 2019, Page(s) 796, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu11040796

Improved fucoxanthin and docosahexaenoic acid productivities of a sorted self-settling Tisochrysis lutea phenotype at pilot scale

Author(s): Fengzheng Gao, Marta Sá, Iago Teles Dominguez Cabanelas, René H. Wijffels, Maria J. Barbosa
Published in: Bioresource Technology, Issue 325, 2021, Page(s) 124725, ISSN 0960-8524
Publisher: Elsevier BV
DOI: 10.1016/j.biortech.2021.124725

Fucoxanthin production from Tisochrysis lutea and Phaeodactylum tricornutum at industrial scale

Author(s): Hugo Pereira, Marta Sá, Inês Maia, Alexandre Rodrigues, Iago Teles, Rene H. Wijffels, João Navalho, Maria Barbosa
Published in: Algal Research, Issue 56, 2021, Page(s) 102322, ISSN 2211-9264
Publisher: Elsevier BV
DOI: 10.1016/j.algal.2021.102322

Light spectra as triggers for sorting improved strains of Tisochrysis lutea

Author(s): Fengzheng Gao, Sep Woolschot, Iago Teles Dominguez Cabanelas, René H. Wijffels, Maria J. Barbosa
Published in: Bioresource Technology, 2020, Page(s) 124434, ISSN 0960-8524
Publisher: Elsevier BV
DOI: 10.1016/j.biortech.2020.124434

Eutectic solvents with tuneable hydrophobicity: lipid dissolution and recovery

Author(s): Calvin Lo, Jeltzlin Semerel, Corjan van den Berg, René H. Wijffels, Michel H. M. Eppink
Published in: RSC Advances, Issue 11/14, 2021, Page(s) 8142-8149, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1ra00306b

Synthetic Biology Approaches To Enhance Microalgal Productivity

Author(s): Mihris Ibnu Saleem Naduthodi, Nico J. Claassens, Sarah D’Adamo, John van der Oost, Maria J. Barbosa
Published in: Trends in Biotechnology, 2021, ISSN 0167-7799
Publisher: Elsevier BV
DOI: 10.1016/j.tibtech.2020.12.010

Other (2)

Info sheet Magnificent

Author(s): Reith, Hans
Published in: Issue 2, 2018
Publisher: Magnificent consortium
DOI: 10.5281/zenodo.3197286

Unlocking the MAGNIFICENT potential of algae in functional aquafeeds

Author(s): Dias, Jorge
Published in: Aquafeed of the future Webinar, October 30 2020, Issue 1, 2020
Publisher: http://eatip.eu/wp-content/uploads/2020/11/Jorge-Dias_ALGAE.pdf
DOI: 10.5281/zenodo.4290226