Objective
"The GOLDENSENS project aims at creating a new class of enantiodiscriminating sensors for methamphetamines based on intrinsically chiral Au38(SR)24 nanoclusters. These materials have unique optical properties which make them capable of conferring chirality to thiols protecting their surface, even when ligands themselves are achiral. The result of this chirality transfer is the formation of an asymmetric environment on the cluster surface which will be used for the enantiodiscrimination of D- and L-methamphetamines which can have distinct biological effects (The D-enantiomer is diffuse as psychotropic drug, whereas the L-enantiomer have been applied in medicine as in nasal decongestant). The first objective of GOLDENSENS will be the preparation of functional Au38 clusters. The protecting thiols of these novel clusters will bear specific chemical groups able to increase the enantioselective interactions with methamphetamines. The second objective will be the investigation of chiral properties of these gold nanoclusters by a combined chiroptical techniques and theoretical calculations. Ultimately, GOLDENSENS will investigate the enantiodiscriminating activity of prepared Au38 clusters towards methamphetamines, leading to the development of novel methods for enantiomeric separation. NMR-based techniques will quantify enantioselective interactions and ""absolute configuration modulation infrared spectroscopy"" will clarify the mechanism of enantiodiscrimination by gold nanoclusters. Results and knowledge generated with GOLDENSENS will impact the understanding of chirality at the nanoscale, contributing to the growth of an emerging and frontier research field. The training provided by the project will help the experienced researcher to refine scientific and soft skills, ultimately acquiring all the abilities and competences necessary to start an independent academic career in nanotechnology.
"
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences optics spectroscopy absorption spectroscopy
- natural sciences chemical sciences catalysis
- natural sciences chemical sciences organic chemistry aliphatic compounds
- natural sciences chemical sciences organic chemistry amines
- natural sciences mathematics applied mathematics mathematical model
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1211 Geneve
Switzerland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.