Objective
The research aim of PhotoNanoBone is to develop of a novel nanotechnological strategy based on stimuli-responsive nanocarriers together with a microfluidic platform for spatiotemporal control of cell reprogramming and differentiation of 3D cell cultures towards bone tissue engineering.
The project entails three steps. (1) Synthesising stimuli-responsive nanocarriers by layer-by-layer assembly and loaded with cell reprogramming factors (cargo). Polymeric walls of nanocarriers will be further functionalized with magnetic and plasmonic nanoparticles. By applying magnetic fields, nanocarriers can be locally enrichment in 3D cell culture. Upon external light irradiation, plasmonic nanoparticles will be heated, leading to local opening of the polymeric walls and subsequent cargo release. (2) Set-up of a microfluidic platform for externally controlled intracellular magnetic targeting and light-triggered release of cargo. (3) Application of the developed technology in 3D cell cultures of fibroblasts (mouse model) for bone tissue engineering.
I (the ER) will prepare, characterize and test the materials and application proposed, with the support of a multidisciplinary hub of specialists.
The prime training aim of PhotoNanoBone is to provide me with a truly solid formation in biomaterials, which will support my future career endeavors, both in the academia or industry, to be an independent researcher, a founder of a start-up company or to become key player in the biomaterials sector.
I will be hosted by the Centre for Research in Biological Chemistry and Molecular Materials (CiQUS) of the University of Santiago de Compostela, a cutting-edge multidisciplinary research center at the interface of chemistry, biomedicine and molecular materials. The training will be further strengthened by two secondments focused on the following topics: synthesis of plasmonic NP with lasers (Complutense University Madrid) and development of microfluidic platforms (Micronit Michrotecnologies).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry
- natural sciences chemical sciences inorganic chemistry transition metals
- natural sciences chemical sciences catalysis
- engineering and technology nanotechnology nano-materials
- natural sciences physical sciences optics laser physics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
15782 Santiago De Compostela
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.