Objective
Conductive polymers (CP) appear as promising stimulus-responsing electroactive biomaterial for profileration of cells. CP are versatile materials that can be synthesized in different shapes and morphologies, offering a wide range of application in biosensing, implants, drug delivery and tissue engineering. Carbon Nanotubes (CNTs) have become promising advanced materials and gained increasing importance for applications in nanomedicine, such as diagnosis, disease treatment, imaging, and tissue engineering. CNTs can interact with cells, cross the biological barriers, and modify their functions and biology. More recently, CNTs have become a new tool to specifically interact with the central nervous systems and support tissue repair after brain damage. Take into account of such findings, we hypothesize that CNTs exert functional effects on networks of cardiac myocytes and, in addition, the combination of those two materials will generate an outstanding scaffold for other electroactive cell growth, such as cardiac cells. In my current research, I have developed 3D scaffolds of CNT with a CP skeleton (polypyrrole or PEDOT) and aftewards, the goal of my research and thus the aim of the current proposal is to test such scaffolds for cardiac tissue regeneration. More specific aims are:
1) Adapt already developed smart “scaffold-matrix supports” for heart tissue engineering and test its viability, comprising CNT and conductive polymers.
2) In vitro and in vivo studies of healthy and genetically modified cardiomyocites (CM) of neonatal and adult rat hearts to determine the interactions between cells and the smart scaffolds and demonstrate that such devices promote heart cell growth and change their electrical properties.
3) Test other carbon nanomaterial scaffolds generated in the host group as supports for cardiac tissue engineering.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences medical biotechnology tissue engineering
- natural sciences chemical sciences polymer sciences
- medical and health sciences medical biotechnology nanomedicine
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-GF - Global Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
48940 Leioa
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.