The Translational Cancer Faster Forward doctoral programme – CanFaster

Información del proyecto

CanFaster

Identificador del acuerdo de subvención: 754299

DOI

10.3030/754299

Proyecto cerrado

Fecha de la firma de la CE 7 Abril 2017

Fecha de inicio 1 Junio 2017

Fecha de finalización 28 Febrero 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 3 348 480,00

Aportación de la UE

€ 1 674 240,00

Coordinado por

LUNDS UNIVERSITET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Thesis and dissertations (6)

Molecular Investigations of high-risk Mantle Cell Lymphoma : Genetic factors and the impact of the microenvironment

Autores: Joana de Matos Rodrigues
Publicado en: 2022
Editor: Department of Immunotechnology, Lund University

Genetic predisposition for Multiple Myeloma. Identification and functional characterization of risk variants

Autores: Laura Duran Lozano
Publicado en: 2022, ISBN 978-91-8021-294-6
Editor: Lund University, Faculty of Medicine

Recovery from Breast Cancer : Investigating the role of resilience in breast cancer survivorship

Autores: Katarina Velickovic
Publicado en: 2022, ISBN 978-91-8039-473-4
Editor: Lund University

The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

Autores: Lavanya Lokhande
Publicado en: 2023, ISBN 978-91-8039-546-5
Editor: Department of Immunotechnology, Lund University

Dissection of the tonsillar cancer immune microenvironment : Perspectives of the myeloid APC – T-cell axis

Autores: David Gomez Jimenez
Publicado en: 2022
Editor: Department of Immunology, Lund University

Novel methods of malignant brain tumor treatment utilizing the tumor microenvironment

Autores: Jan Kopecky
Publicado en: 2022, ISBN 978-91-8021-251-9
Editor: Lund University, Faculty of Medicine

Peer reviewed articles (27)

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

Autores: Ram Ajore, Abhishek Niroula, Maroulio Pertesi, Caterina Cafaro, Malte Thodberg, Molly Went, Erik L. Bao, Laura Duran-Lozano, Aitzkoa Lopez de Lapuente Portilla, Thorunn Olafsdottir, Nerea Ugidos-Damboriena, Olafur Magnusson, Mehmet Samur, Caleb A. Lareau, Gisli H. Halldorsson, Gudmar Thorleifsson, Gudmundur L. Norddahl, Kristbjorg Gunnarsdottir, Asta Försti, Hartmut Goldschmidt, Kari Hemminki, Fr
Publicado en: Nature Communications, Edición 13/1, 2022, Página(s) 151, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-27666-x

Intratumoral administration of the antisecretory peptide AF16 cures murine gliomas and modulates macrophage functions

Autores: Jan Kopecky; Julio Enríquez Pérez; Håkan Eriksson; Edward Visse; Peter Siesjö; Anna Darabi
Publicado en: Scientific Reports, Edición 12/1, 2022, Página(s) 4609, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-08618-x

Immune-related protein signature in serum stratify relapsed mantle cell lymphoma patients based on risk

Autores: Lavanya Lokhande, Venera Kuci Emruli, Arne Kolstad, Martin Hutchings, Riikka Räty, Mats Jerkeman, Sara Ek
Publicado en: BMC Cancer, Edición 20/1, 2020, ISSN 1471-2407
Editor: BioMed Central
DOI: 10.1186/s12885-020-07678-4

Single-cell analysis of myeloid cells in HPV+ tonsillar cancer

Autores: David Gomez Jimenez, Can Altunbulakli, Sabine Swoboda, Aastha Sobti, David Askmyr,Ashfaq Ali, Lennart Greiff, Malin Lindstedt
Publicado en: Frontiers in Immunology, Edición 13, 2022, ISSN 2692-8205
Editor: bioRxiv
DOI: 10.1101/2022.10.04.510291

Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets

Autores: Joana M. Rodrigues, Anna Porwit, May Hassan, Sara Ek, Mats Jerkeman
Publicado en: Leukemia & Lymphoma, 2021, Página(s) 1-11, ISSN 1042-8194
Editor: Taylor & Francis
DOI: 10.1080/10428194.2021.1933480

Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high dose chemotherapy independent of MIPI and complement established high-risk factors

Autores: Anna Sandström Gerdtsson, Joana de Matos Rodrigues, Christian Winther Eskelund, Simon Husby, Kirsten Grønbæk, Riikka Räty, Arne Kolstad, Christian Geisler, Anna Porwit, Mats Jerkeman, Sara Ek
Publicado en: Haematologica, 2022, ISSN 0390-6078
Editor: Ferrata Storti Foundation
DOI: 10.3324/haematol.2022.281420

Clinical associations of ESR2 (estrogen receptor beta) expression across thousands of primary breast tumors

Autores: Hina Dalal; Malin Dahlgren; Sergii Gladchuk; Christian Brueffer; Sofia K. Gruvberger-Saal; Lao H. Saal
Publicado en: Scientific Reports, Edición 20452322, 2022, Página(s) 4696, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-08210-3

Serum proteome modulations upon treatment provides biological insight on response to treatment in relapsed mantle cell lymphoma

Autores: Lavanya Lokhande, Venera Kuci Emruli, Christian Winther Eskelund, Arne Kolstad, Martin Hutchings, Riikka Räty, Carsten Utoft Niemann, Kirsten Grønbæk, Mats Jerkeman, Sara Ek
Publicado en: Cancer Reports, Edición 5/7, 2022, Página(s) e1524, ISSN 2573-8348
Editor: Wiley Periodicals, LLC
DOI: 10.1002/cnr2.1524

Germline variants at SOHLH2 influence multiple myeloma risk

Autores: Laura Duran-Lozano, Gudmar Thorleifsson, Aitzkoa Lopez de Lapuente Portilla, Abhishek Niroula, Molly Went, Malte Thodberg, Maroulio Pertesi, Ram Ajore, Caterina Cafaro, Pall I. Olason, Lilja Stefansdottir, G. Bragi Walters, Gisli H. Halldorsson, Ingemar Turesson, Martin F. Kaiser, Niels Weinhold, Niels Abildgaard, Niels Frost Andersen, Ulf-Henrik Mellqvist, Anders Waage, Annette Juul-Vangsted, Unn
Publicado en: Blood Cancer Journal, Edición 11/4, 2021, ISSN 2044-5385
Editor: Nature Publishing Group
DOI: 10.1038/s41408-021-00468-6

Physical Activity and Long-Term Risk of Breast Cancer, Associations with Time in Life and Body Composition in the Prospective Malmö Diet and Cancer Study

Autores: Öykü Boraka, Marie Klintman, Ann H. Rosendahl
Publicado en: Cancers, Edición 14/8, 2022, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081960

Size‑based isolation and detection of renal carcinoma cells from whole blood

Autores: Roger De Alwis Jennifer Hansson David Lindgren Sarah Schoch Alexander Tejera Bianca Scholtz Peter Elfving Christina Möller Helén Nilsson Martin Johansson Håkan Axelson
Publicado en: Molecular and Clinical Oncology, Edición 16/5, 2022, ISSN 2049-9469
Editor: Spandidos Publications UK
DOI: 10.3892/mco.2022.2534

Clinical and biological impact of SAMHD1 expression in mantle cell lymphoma

Autores: Magali Merrien, Agata M Wasik, Elin Ljung, Mohammad H A Morsy, Joana de Matos Rodrigues, Mattias Carlsten, Georgios Z Rassidakis, Birger Christensson, Arne Kolstad, Mats Jerkeman, Sara Ek, Nikolas Herold, Björn E Wahlin, Birgitta Sander.
Publicado en: Virchows Archiv, Edición 480/3, 2021, Página(s) 655-666, ISSN 0945-6317
Editor: Springer Verlag
DOI: 10.1007/s00428-021-03228-w

Tonsillar Cancer with High CD8+ T-Cell Infiltration Features Increased Levels of Dendritic Cells and Transcriptional Regulation Associated with an Inflamed Tumor Microenvironment.

Autores: David Gomez Jimenez, Aastha Sobti, David Askmyr, Christina Sakellariou, Sofia Carreira Santos, Sabine Swoboda, Ola Forslund, Lennart Greiff, Malin Lindstedt
Publicado en: Cancers, Edición 20726694, 2021, Página(s) 5341, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13215341

p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Autores: Joana M. Rodrigues, May Hassan, Catja Freiburghaus, Christian W. Eskelund, Christian Geisler, Riikka Räty, Arne Kolstad, Christer Sundström, Ingrid Glimelius, Kirsten Grønbæk, Anna Kwiecinska, Anna Porwit, Mats Jerkeman, Sara Ek
Publicado en: British Journal of Haematology, Edición 191/5, 2020, ISSN 0007-1048
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17023

Plasma proteome profiling of healthy individuals across the life span in a Sicilian cohort with long-lived individuals

Autores: Valentina Siino, Ashfaq Ali, Giulia Accardi, Anna Aiello, Mattia E. Ligotti, Sergio Mosquim Junior, Giuseppina Candore, Calogero Caruso, Fredrik Levander, Sonya Vasto
Publicado en: Aging Cell, Edición 14749718, 2022, Página(s) e13684, ISSN 1474-9718
Editor: Blackwell Publishing Inc.
DOI: 10.1111/acel.13684

Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels

Autores: Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Caterina Cafaro, Zain Ali, Natsumi Miharada, Gudmar Thorleifsson, Kristijonas Žemaitis, Antton Lamarca Arrizabalaga, Malte Thodberg, Maroulio Pertesi, Parashar Dhapola, Erik Bao, Abhishek Niroula, Divya Bali, Gudmundur Norddahl, Nerea Ugidos Damboriena, Vijay G. Sankaran, Göran Karlsson, Unnur Thorsteinsdottir, Jonas Larsson, Kari Stefansson, Bj
Publicado en: Blood, Edición 139 (11), 2022, Página(s) 1659–1669, ISSN 1528-0020
Editor: American Society of Hematology
DOI: 10.1182/blood.2021013220

Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization

Autores: Valeria Governa, Hugo Talbot, Kelin Gonçalves de Oliveira, Myriam Cerezo-Magaña, Anna Bång-Rudenstam, Maria C Johansson, Ann-Sofie Månsson, Karin Forsberg-Nilsson, György Marko-Varga, Julio Enríquez Pérez, Anna Darabi, Johan Malmström, Johan Bengzon, Charlotte Welinder, Mattias Belting
Publicado en: PNAS, Edición 119/9, 2022, ISSN 1091-6490
Editor: Washington D.C.: The Academy
DOI: 10.1073/pnas.2114456119

Convection-enhanced delivery of temozolomide and whole cell tumor immunizations in GL261 and KR158 experimental mouse gliomas

Autores: Julio Enríquez Pérez, Jan Kopecky, Edward Visse, Anna Darabi, Peter Siesjö
Publicado en: BMC Cancer, Edición 20/1, 2020, ISSN 1471-2407
Editor: BioMed Central
DOI: 10.1186/s12885-019-6502-7

Psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) in a non-clinical population in Sweden

Autores: Katarina Velickovic, Ingalill Rahm Hallberg, Ulrika Axelsson, Carl A. K. Borrebaeck, Lisa Rydén, Per Johnsson, Johanna Månsson
Publicado en: Health and Quality of Life Outcomes, Edición 18/1, 2020, ISSN 1477-7525
Editor: BioMed Central
DOI: 10.1186/s12955-020-01383-3

CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

Autores: Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, Maria Rodriguez-Zabala, Marion Chapellier, Carl Högberg, Mia Eriksson, David Yudovich, Mansi Shah, Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Benjamin L. Ebert, Ravi Bhatia, Marcus Järås
Publicado en: Cell Reports, Edición 31/8, 2020, Página(s) 107684, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2020.107684

Case Report: Co-Infection of Streptococcus Dysgalactiae Subspecies Equisimilis and HPV11 in Laryngeal Papilloma

Autores: Aastha Sobti, Malin Lindstedt, Fredrik Andersson, Roland Rydell, Ola Forslund
Publicado en: Annals of Case Reports, Edición 7: 993, 2022, ISSN 2574-7754
Editor: Gavin Publishers
DOI: 10.29011/2574-7754.100993

Immune Phenotypes of Nasopharyngeal Cancer

Autores: Johan S. Nilsson, Aastha Sobti, Sabine Swoboda, Jonas S. Erjefält, Ola Forslund, Malin Lindstedt, Lennart Greiff
Publicado en: Cancers, Edición 12/11, 2020, Página(s) 3428, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12113428

Immune delineation of laryngeal papilloma reveals enhanced neutrophil associated gene profile

Autores: Aastha Sobti, Christina Sakellariou, Maile Nilsson, Stefan Schwartz, Katarina Olofsson, Roland Rydell, Malin Lindstedt, Ola Forslund
Publicado en: European Journal of Immunology, Edición 15214141, 2021, Página(s) 2535-2539, ISSN 1521-4141
Editor: Wiley-VCH GmbH
DOI: 10.1002/eji.202149202

Choice of High-Throughput Proteomics Method Affects Data Integration with Transcriptomics and the Potential Use in Biomarker Discovery

Autores: Sergio Mosquim Junior, Valentina Siino, Lisa Rydén, Johan Vallon-Christersson, Fredrik Levander
Publicado en: Cancers, Edición 14(23), 2022, Página(s) 5761, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14235761

Subpopulations of Organoid-Forming Cells Have Different Motility

Autores: David Gomez Jimenez, Sofia Carreira Santos, Lennart Greiff, Kersti Alm, Malin Lindstedt
Publicado en: Applied Sciences, Edición 10/13, 2020, Página(s) 4673, ISSN 2076-3417
Editor: mdpi
DOI: 10.3390/app10134673

Infiltration of CD163‐, PD‐L1‐ and FoxP3‐positive cells adversely affects outcome in patients with mantle cell lymphoma independent of established risk factors

Autores: Joana M. Rodrigues, Anna Nikkarinen, Peter Hollander, Caroline E. Weibull, Riikka Räty, Arne Kolstad, Rose‐Marie Amini, Anna Porwit, Mats Jerkeman, Sara Ek, Ingrid Glimelius
Publicado en: British Journal of Haematology, Edición 193/3, 2021, Página(s) 520-531, ISSN 0007-1048
Editor: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17366

One-year recovery from breast cancer: Importance of tumor and treatment-related factors, resilience, and sociodemographic factors for health-related quality of life

Autores: Katarina Veličković, Carl A K Borrebaeck, Pär-Ola Bendahl, Cecilia Hegardt, Per Johnsson, Corinna Richter, Lisa Rydén, Ingalill Rahm Hallberg
Publicado en: Frontiers in Oncology, Edición 12, 2022, Página(s) 891850, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.891850