The Translational Cancer Faster Forward doctoral programme – CanFaster

Informazioni relative al progetto

CanFaster

ID dell’accordo di sovvenzione: 754299

DOI

10.3030/754299

Progetto chiuso

Data della firma CE 7 Aprile 2017

Data di avvio 1 Giugno 2017

Data di completamento 28 Febbraio 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 3 348 480,00

Contributo UE

€ 1 674 240,00

Coordinato da

LUNDS UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Thesis and dissertations (6)

Molecular Investigations of high-risk Mantle Cell Lymphoma : Genetic factors and the impact of the microenvironment

Autori: Joana de Matos Rodrigues
Pubblicato in: 2022
Editore: Department of Immunotechnology, Lund University

Genetic predisposition for Multiple Myeloma. Identification and functional characterization of risk variants

Autori: Laura Duran Lozano
Pubblicato in: 2022, ISBN 978-91-8021-294-6
Editore: Lund University, Faculty of Medicine

Recovery from Breast Cancer : Investigating the role of resilience in breast cancer survivorship

Autori: Katarina Velickovic
Pubblicato in: 2022, ISBN 978-91-8039-473-4
Editore: Lund University

The immune microenvironment in mantle cell lymphoma : Targeted liquid and spatial proteomic analyses

Autori: Lavanya Lokhande
Pubblicato in: 2023, ISBN 978-91-8039-546-5
Editore: Department of Immunotechnology, Lund University

Dissection of the tonsillar cancer immune microenvironment : Perspectives of the myeloid APC – T-cell axis

Autori: David Gomez Jimenez
Pubblicato in: 2022
Editore: Department of Immunology, Lund University

Novel methods of malignant brain tumor treatment utilizing the tumor microenvironment

Autori: Jan Kopecky
Pubblicato in: 2022, ISBN 978-91-8021-251-9
Editore: Lund University, Faculty of Medicine

Peer reviewed articles (27)

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

Autori: Ram Ajore, Abhishek Niroula, Maroulio Pertesi, Caterina Cafaro, Malte Thodberg, Molly Went, Erik L. Bao, Laura Duran-Lozano, Aitzkoa Lopez de Lapuente Portilla, Thorunn Olafsdottir, Nerea Ugidos-Damboriena, Olafur Magnusson, Mehmet Samur, Caleb A. Lareau, Gisli H. Halldorsson, Gudmar Thorleifsson, Gudmundur L. Norddahl, Kristbjorg Gunnarsdottir, Asta Försti, Hartmut Goldschmidt, Kari Hemminki, Fr
Pubblicato in: Nature Communications, Numero 13/1, 2022, Pagina/e 151, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-27666-x

Intratumoral administration of the antisecretory peptide AF16 cures murine gliomas and modulates macrophage functions

Autori: Jan Kopecky; Julio Enríquez Pérez; Håkan Eriksson; Edward Visse; Peter Siesjö; Anna Darabi
Pubblicato in: Scientific Reports, Numero 12/1, 2022, Pagina/e 4609, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-08618-x

Immune-related protein signature in serum stratify relapsed mantle cell lymphoma patients based on risk

Autori: Lavanya Lokhande, Venera Kuci Emruli, Arne Kolstad, Martin Hutchings, Riikka Räty, Mats Jerkeman, Sara Ek
Pubblicato in: BMC Cancer, Numero 20/1, 2020, ISSN 1471-2407
Editore: BioMed Central
DOI: 10.1186/s12885-020-07678-4

Single-cell analysis of myeloid cells in HPV+ tonsillar cancer

Autori: David Gomez Jimenez, Can Altunbulakli, Sabine Swoboda, Aastha Sobti, David Askmyr,Ashfaq Ali, Lennart Greiff, Malin Lindstedt
Pubblicato in: Frontiers in Immunology, Numero 13, 2022, ISSN 2692-8205
Editore: bioRxiv
DOI: 10.1101/2022.10.04.510291

Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets

Autori: Joana M. Rodrigues, Anna Porwit, May Hassan, Sara Ek, Mats Jerkeman
Pubblicato in: Leukemia & Lymphoma, 2021, Pagina/e 1-11, ISSN 1042-8194
Editore: Taylor & Francis
DOI: 10.1080/10428194.2021.1933480

Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high dose chemotherapy independent of MIPI and complement established high-risk factors

Autori: Anna Sandström Gerdtsson, Joana de Matos Rodrigues, Christian Winther Eskelund, Simon Husby, Kirsten Grønbæk, Riikka Räty, Arne Kolstad, Christian Geisler, Anna Porwit, Mats Jerkeman, Sara Ek
Pubblicato in: Haematologica, 2022, ISSN 0390-6078
Editore: Ferrata Storti Foundation
DOI: 10.3324/haematol.2022.281420

Clinical associations of ESR2 (estrogen receptor beta) expression across thousands of primary breast tumors

Autori: Hina Dalal; Malin Dahlgren; Sergii Gladchuk; Christian Brueffer; Sofia K. Gruvberger-Saal; Lao H. Saal
Pubblicato in: Scientific Reports, Numero 20452322, 2022, Pagina/e 4696, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-08210-3

Serum proteome modulations upon treatment provides biological insight on response to treatment in relapsed mantle cell lymphoma

Autori: Lavanya Lokhande, Venera Kuci Emruli, Christian Winther Eskelund, Arne Kolstad, Martin Hutchings, Riikka Räty, Carsten Utoft Niemann, Kirsten Grønbæk, Mats Jerkeman, Sara Ek
Pubblicato in: Cancer Reports, Numero 5/7, 2022, Pagina/e e1524, ISSN 2573-8348
Editore: Wiley Periodicals, LLC
DOI: 10.1002/cnr2.1524

Germline variants at SOHLH2 influence multiple myeloma risk

Autori: Laura Duran-Lozano, Gudmar Thorleifsson, Aitzkoa Lopez de Lapuente Portilla, Abhishek Niroula, Molly Went, Malte Thodberg, Maroulio Pertesi, Ram Ajore, Caterina Cafaro, Pall I. Olason, Lilja Stefansdottir, G. Bragi Walters, Gisli H. Halldorsson, Ingemar Turesson, Martin F. Kaiser, Niels Weinhold, Niels Abildgaard, Niels Frost Andersen, Ulf-Henrik Mellqvist, Anders Waage, Annette Juul-Vangsted, Unn
Pubblicato in: Blood Cancer Journal, Numero 11/4, 2021, ISSN 2044-5385
Editore: Nature Publishing Group
DOI: 10.1038/s41408-021-00468-6

Physical Activity and Long-Term Risk of Breast Cancer, Associations with Time in Life and Body Composition in the Prospective Malmö Diet and Cancer Study

Autori: Öykü Boraka, Marie Klintman, Ann H. Rosendahl
Pubblicato in: Cancers, Numero 14/8, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081960

Size‑based isolation and detection of renal carcinoma cells from whole blood

Autori: Roger De Alwis Jennifer Hansson David Lindgren Sarah Schoch Alexander Tejera Bianca Scholtz Peter Elfving Christina Möller Helén Nilsson Martin Johansson Håkan Axelson
Pubblicato in: Molecular and Clinical Oncology, Numero 16/5, 2022, ISSN 2049-9469
Editore: Spandidos Publications UK
DOI: 10.3892/mco.2022.2534

Clinical and biological impact of SAMHD1 expression in mantle cell lymphoma

Autori: Magali Merrien, Agata M Wasik, Elin Ljung, Mohammad H A Morsy, Joana de Matos Rodrigues, Mattias Carlsten, Georgios Z Rassidakis, Birger Christensson, Arne Kolstad, Mats Jerkeman, Sara Ek, Nikolas Herold, Björn E Wahlin, Birgitta Sander.
Pubblicato in: Virchows Archiv, Numero 480/3, 2021, Pagina/e 655-666, ISSN 0945-6317
Editore: Springer Verlag
DOI: 10.1007/s00428-021-03228-w

Tonsillar Cancer with High CD8+ T-Cell Infiltration Features Increased Levels of Dendritic Cells and Transcriptional Regulation Associated with an Inflamed Tumor Microenvironment.

Autori: David Gomez Jimenez, Aastha Sobti, David Askmyr, Christina Sakellariou, Sofia Carreira Santos, Sabine Swoboda, Ola Forslund, Lennart Greiff, Malin Lindstedt
Pubblicato in: Cancers, Numero 20726694, 2021, Pagina/e 5341, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13215341

p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Autori: Joana M. Rodrigues, May Hassan, Catja Freiburghaus, Christian W. Eskelund, Christian Geisler, Riikka Räty, Arne Kolstad, Christer Sundström, Ingrid Glimelius, Kirsten Grønbæk, Anna Kwiecinska, Anna Porwit, Mats Jerkeman, Sara Ek
Pubblicato in: British Journal of Haematology, Numero 191/5, 2020, ISSN 0007-1048
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17023

Plasma proteome profiling of healthy individuals across the life span in a Sicilian cohort with long-lived individuals

Autori: Valentina Siino, Ashfaq Ali, Giulia Accardi, Anna Aiello, Mattia E. Ligotti, Sergio Mosquim Junior, Giuseppina Candore, Calogero Caruso, Fredrik Levander, Sonya Vasto
Pubblicato in: Aging Cell, Numero 14749718, 2022, Pagina/e e13684, ISSN 1474-9718
Editore: Blackwell Publishing Inc.
DOI: 10.1111/acel.13684

Genome-wide association study on 13 167 individuals identifies regulators of blood CD34+cell levels

Autori: Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Caterina Cafaro, Zain Ali, Natsumi Miharada, Gudmar Thorleifsson, Kristijonas Žemaitis, Antton Lamarca Arrizabalaga, Malte Thodberg, Maroulio Pertesi, Parashar Dhapola, Erik Bao, Abhishek Niroula, Divya Bali, Gudmundur Norddahl, Nerea Ugidos Damboriena, Vijay G. Sankaran, Göran Karlsson, Unnur Thorsteinsdottir, Jonas Larsson, Kari Stefansson, Bj
Pubblicato in: Blood, Numero 139 (11), 2022, Pagina/e 1659–1669, ISSN 1528-0020
Editore: American Society of Hematology
DOI: 10.1182/blood.2021013220

Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization

Autori: Valeria Governa, Hugo Talbot, Kelin Gonçalves de Oliveira, Myriam Cerezo-Magaña, Anna Bång-Rudenstam, Maria C Johansson, Ann-Sofie Månsson, Karin Forsberg-Nilsson, György Marko-Varga, Julio Enríquez Pérez, Anna Darabi, Johan Malmström, Johan Bengzon, Charlotte Welinder, Mattias Belting
Pubblicato in: PNAS, Numero 119/9, 2022, ISSN 1091-6490
Editore: Washington D.C.: The Academy
DOI: 10.1073/pnas.2114456119

Convection-enhanced delivery of temozolomide and whole cell tumor immunizations in GL261 and KR158 experimental mouse gliomas

Autori: Julio Enríquez Pérez, Jan Kopecky, Edward Visse, Anna Darabi, Peter Siesjö
Pubblicato in: BMC Cancer, Numero 20/1, 2020, ISSN 1471-2407
Editore: BioMed Central
DOI: 10.1186/s12885-019-6502-7

Psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) in a non-clinical population in Sweden

Autori: Katarina Velickovic, Ingalill Rahm Hallberg, Ulrika Axelsson, Carl A. K. Borrebaeck, Lisa Rydén, Per Johnsson, Johanna Månsson
Pubblicato in: Health and Quality of Life Outcomes, Numero 18/1, 2020, ISSN 1477-7525
Editore: BioMed Central
DOI: 10.1186/s12955-020-01383-3

CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

Autori: Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, Maria Rodriguez-Zabala, Marion Chapellier, Carl Högberg, Mia Eriksson, David Yudovich, Mansi Shah, Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Benjamin L. Ebert, Ravi Bhatia, Marcus Järås
Pubblicato in: Cell Reports, Numero 31/8, 2020, Pagina/e 107684, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.107684

Case Report: Co-Infection of Streptococcus Dysgalactiae Subspecies Equisimilis and HPV11 in Laryngeal Papilloma

Autori: Aastha Sobti, Malin Lindstedt, Fredrik Andersson, Roland Rydell, Ola Forslund
Pubblicato in: Annals of Case Reports, Numero 7: 993, 2022, ISSN 2574-7754
Editore: Gavin Publishers
DOI: 10.29011/2574-7754.100993

Immune Phenotypes of Nasopharyngeal Cancer

Autori: Johan S. Nilsson, Aastha Sobti, Sabine Swoboda, Jonas S. Erjefält, Ola Forslund, Malin Lindstedt, Lennart Greiff
Pubblicato in: Cancers, Numero 12/11, 2020, Pagina/e 3428, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12113428

Immune delineation of laryngeal papilloma reveals enhanced neutrophil associated gene profile

Autori: Aastha Sobti, Christina Sakellariou, Maile Nilsson, Stefan Schwartz, Katarina Olofsson, Roland Rydell, Malin Lindstedt, Ola Forslund
Pubblicato in: European Journal of Immunology, Numero 15214141, 2021, Pagina/e 2535-2539, ISSN 1521-4141
Editore: Wiley-VCH GmbH
DOI: 10.1002/eji.202149202

Choice of High-Throughput Proteomics Method Affects Data Integration with Transcriptomics and the Potential Use in Biomarker Discovery

Autori: Sergio Mosquim Junior, Valentina Siino, Lisa Rydén, Johan Vallon-Christersson, Fredrik Levander
Pubblicato in: Cancers, Numero 14(23), 2022, Pagina/e 5761, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14235761

Subpopulations of Organoid-Forming Cells Have Different Motility

Autori: David Gomez Jimenez, Sofia Carreira Santos, Lennart Greiff, Kersti Alm, Malin Lindstedt
Pubblicato in: Applied Sciences, Numero 10/13, 2020, Pagina/e 4673, ISSN 2076-3417
Editore: mdpi
DOI: 10.3390/app10134673

Infiltration of CD163‐, PD‐L1‐ and FoxP3‐positive cells adversely affects outcome in patients with mantle cell lymphoma independent of established risk factors

Autori: Joana M. Rodrigues, Anna Nikkarinen, Peter Hollander, Caroline E. Weibull, Riikka Räty, Arne Kolstad, Rose‐Marie Amini, Anna Porwit, Mats Jerkeman, Sara Ek, Ingrid Glimelius
Pubblicato in: British Journal of Haematology, Numero 193/3, 2021, Pagina/e 520-531, ISSN 0007-1048
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17366

One-year recovery from breast cancer: Importance of tumor and treatment-related factors, resilience, and sociodemographic factors for health-related quality of life

Autori: Katarina Veličković, Carl A K Borrebaeck, Pär-Ola Bendahl, Cecilia Hegardt, Per Johnsson, Corinna Richter, Lisa Rydén, Ingalill Rahm Hallberg
Pubblicato in: Frontiers in Oncology, Numero 12, 2022, Pagina/e 891850, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.891850