Livrables
A kit protocol for the ELISA’s for hCRP, IL-6, IL-10, CCL2, PTX3, sCD25, IL-7, SCF, IGFBP-2 and BDNF (or a selection of those factors) and other found serum cytokines and growth factors discriminating active mood disorders and helpful in determining therapy responsiveness.
A PAXGENE kit protocolA kit protocol for a Q-PCR on PAXGENE material for the key genes of cluster 1 and 2 , the IFN cluster and, if relevant, also for growth and apoptosis genes discriminating active mood disorders and helpful in determining therapy responsiveness.
The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
List of seminars for patients M24Reports and programs of seminars organized for patient organizations
Website update M66Update of the website as described earlier
Website update M1The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
Website update M30The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
General public communications M24A two-yearly list of lay press articles, television documentaries and other general public communications
General public communications M60A twoyearly list of lay press articles television documentaries and other general public communications
Website update M42The 6 monthly update of the website wwwmoodinflameeu with a newsletters and photographs of our open houses
Website update M6The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
Website update M60Update of the website as described earlier
Website update M36The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
Website update M24The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
Neuro-immunology bookA neuroimmunology book for psychiatrists
Website update M18The 6 monthly update of the web-site www.moodinflame.eu (with a newsletters and photographs of our open houses
List of seminars for patients M52Reports and programs of seminars organized for patient organizations
Website update M52The 6 monthly update of the website wwwmoodinflameeu with a newsletters and photographs of our open houses
Neuro-immunology course programs M24The programs of neuroimmunology courses organized for psychiatrists
Neuro-immunology course programs M60The programs of neuroimmunology courses organized for psychiatrists
List of scientific publications till M66
Scientific publication list M52A yearly list of scientific publications and publications in clinical journals
Abstract list M66Lists of abstracts of presentations at scientifiv meetings till M66
Kick off reportReport of the kick off meeting
Abstract list M52A yearly list of abstracts of contributions to scientific meetings
Ethical approval thymosin alpha studyFirst study subject approvals package for the thymosin clinical investigations
Approval immune stratification studies (IMMUNOSTRATA)First study subject approvals package for the study with immune stratification IMMUNOSTRATA
Fourth annual meeting reportReport of the fourth annual meeting of the general assembly
Scientific publication list M24A yearly list of scientific publications and publications in clinical journals
Abstract list M24A yearly list of abstracts of contributions to scientific meetings
In silico brain analysis for inflammation/growth pathwaysReport on the in silico analysis of human brain bank specimens of patients and controls with regard to IL17 TGFbeta BDNF and inflammation eg IL6 TNF CCL20 linked pathways
Midterm recruitment immune stratification study (IMMUNOSTRATA)Midterm recruitment report for immune stratification prediction for the outcome of physical endurance therapy for MDD
Third annual meeting reportReport of the third annual meeting of the general assembly
First annual meeting reportReport of the first annual meeting of the general assembly
Socio-political contacts M60Reports of the liaison officer with the Dutch Ministry of Health other health care officials and EU officials involved in health care policy making
Midterm meeting reportReport of the midterm meeting of the general assembly, with special emphasis on the decisions made with regard to the final composition of the immune signatures and the decisions made on the choice for anti-inflammatory and T cell enforcement therapies
Data management planA data management plan
Ethical approval treatment as usual studyFirst study subject approvals package for the study with treatment as usual (simple recording of improvement of mood state in patients)
Ethical approval IL-2 studyFirst study subject approvals package for the low dose IL-2 clinical investigations
Mood state in CVIDReport on the study on the prevalence of fatigue and depression in CVID patients with and without reduced numbers of T cells
A comprehensive data bank of the laboratory and clinical data of MOODSTRATIFICATION open to the scientific community at large
Publications
Auteurs:
Carmen Schiweck, Stephan Claes, Lukas Van Oudenhove, Ginette Lafit, Thomas Vaessen, Gommaar Op de Beeck, Raf Berghmans, Annemarie Wijkhuijs, Norbert Müller, Volker Arolt, Hemmo Drexhage, Elske Vrieze
Publié dans:
Translational Psychiatry, Numéro 10/1, 2020, ISSN 2158-3188
Éditeur:
Nature Publishing Group
DOI:
10.1038/s41398-020-00979-z
Auteurs:
Olivia Manusama 1, Sajni Singh 1, Rik A Brooimans 1, Annemarie Wijkhuijs 1, Marianne van der Ent 1, Hemmo A Drexhage 2, Virgil A Dalm 1
Publié dans:
International Immunopharmacology, Numéro 2023 June, 2023, ISSN 1878-1705
Éditeur:
Elsevier
DOI:
10.1016/j.intimp.2023.110168
Auteurs:
Comai S, Melloni E, Lorenzi C, Bollettini I, Vai B, Zanardi R, Colombo C, Valtorta F, Benedetti F, Poletti S
Publié dans:
Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression, 2022, ISSN 0924-977X
Éditeur:
Elsevier BV
DOI:
10.1016/j.euroneuro.2021.11.003
Auteurs:
Lauren M. Osborne, Janneke Gilden, Astrid M. Kamperman, Witte J.G. Hoogendijk, Julie Spicer, Hemmo A. Drexhage, Veerle Bergink
Publié dans:
Brain, Behavior, and Immunity, Numéro 87, 2020, Page(s) 397-403, ISSN 0889-1591
Éditeur:
Academic Press
DOI:
10.1016/j.bbi.2020.01.007
Auteurs:
Poletti S, Mazza MG, Calesella F, Vai B, Lorenzi C, Manfredi E, Colombo C, Zanardi R, Benedetti F
Publié dans:
Circulating inflammatory markers impact cognitive functions in bipolar depression, 2021, ISSN 0022-3956
Éditeur:
Pergamon Press Ltd.
DOI:
10.1016/j.jpsychires.2021.05.071
Auteurs:
Carmen Schiweck, Mireia Valles-Colomer, Volker Arolt, Norbert Müller, Jeroen Raes, Annemarie Wijkhuijs, Stephan Claes, Hemmo Drexhage, Elske Vrieze
Publié dans:
Brain, Behavior, and Immunity, Numéro 87, 2020, Page(s) 603-609, ISSN 0889-1591
Éditeur:
Academic Press
DOI:
10.1016/j.bbi.2020.02.005
Auteurs:
Benedetti F, Poletti S, Vai B, Mazza GM, Lorenzi C, Brioschi S, Aggio V, Branchi I, Colombo C, Furlan R, Zanardi R
Publié dans:
Higher baseline interleukin-1β and TNF-α hamper antidepressant response in major depressive disorder, 2021, ISSN 0924-977X
Éditeur:
Elsevier BV
DOI:
10.1016/j.euroneuro.2020.11.009
Auteurs:
Maria S Simon 1, Magdalini Ioannou 2, Gara Arteaga-Henríquez 3 4, Annemarie Wijkhuijs 5, Raf Berghmans 6, Richard Musil 1, Norbert Müller 1, Hemmo A Drexhage 5
Publié dans:
Brain Behav Immun Health, Numéro 2023, 2023, ISSN 2666-3546
Éditeur:
elsevier
DOI:
10.1016/j.bbih.2023.100608
Auteurs:
Drexhage H.A.
Publié dans:
Journal of Affective Disorders Reports Volume 12, Numéro 12, 2023, ISSN 2666-9153
Éditeur:
Elsevier
DOI:
10.1016/j.jadr.2023.100537
Auteurs:
Sara Poletti, Mario Gennaro Mazza, Benedetta Vai, Cristina Lorenzi, Cristina Colombo, Francesco Benedetti
Publié dans:
Frontiers in Psychiatry, Numéro 11, 2020, ISSN 1664-0640
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fpsyt.2020.590095
Auteurs:
Kathrine Bang Madsen, Oleguer Plana-Ripoll, Katherine L. Musliner, Jean-Christophe Philippe Debost, Liselotte Vogdrup Petersen, Trine Munk-Olsen
Publié dans:
Journal of Affective Disorders, Numéro 280, 2021, Page(s) 250-257, ISSN 0165-0327
Éditeur:
Elsevier BV
DOI:
10.1016/j.jad.2020.11.042
Auteurs:
Scheiber C, Schulz T, Schneider JM, Bechter K, Schneider EM
Publié dans:
Old and New Biomarkers for Infection, Inflammation, and Autoimmunity in Treatment-Resistant Affective and Schizophrenic Spectrum Disorders, 2022, ISSN 1424-8247
Éditeur:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ph15030299
Auteurs:
Thomas A Pollak, Belinda R Lennox, Sabine Müller, Michael E Benros, Harald Prüss, Ludger Tebartz van Elst, Hans Klein, Johann Steiner, Thomas Frodl, Bernhard Bogerts, Li Tian, Laurent Groc, Alkomiet Hasan, Bernhard T Baune, Dominique Endres, Ebrahim Haroon, Robert Yolken, Francesco Benedetti, Angelos Halaris, Jeffrey H Meyer, Hans Stassen, Marion Leboyer, Dietmar Fuchs, Markus Otto, David A Brow
Publié dans:
The Lancet Psychiatry, Numéro 7/1, 2020, Page(s) 93-108, ISSN 2215-0366
Éditeur:
Elsevier Limited
DOI:
10.1016/s2215-0366(19)30290-1
Auteurs:
Simon MS, Burger B, Weidinger E, Arteaga-Henríquez G, Zill P, Musil R, Drexhage HA, Müller N
Publié dans:
Efficacy of Sertraline Plus Placebo or Add-On Celecoxib in Major Depressive Disorder: Macrophage Migration Inhibitory Factor as a Promising Biomarker for Remission After Sertraline-Results From a Randomized Controlled Clinical Trial., 2021, ISSN 1664-0640
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fpsyt.2021.615261
Auteurs:
Gara Arteaga-Henríquez, Maria S. Simon, Bianka Burger, Elif Weidinger, Annemarie Wijkhuijs, Volker Arolt, Tom K. Birkenhager, Richard Musil, Norbert Müller, Hemmo A. Drexhage
Publié dans:
Frontiers in Psychiatry, Numéro 10, 2019, ISSN 1664-0640
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fpsyt.2019.00458
Auteurs:
Karlijn Becking, Bartholomeus C.M. Haarman, Laura Grosse, Willem A. Nolen, Stephan Claes, Volker Arolt, Robert A. Schoevers, Hemmo A. Drexhage
Publié dans:
Journal of Neuroimmunology, Numéro 319, 2018, Page(s) 28-36, ISSN 0165-5728
Éditeur:
Elsevier BV
DOI:
10.1016/j.jneuroim.2018.03.004
Auteurs:
Gara Arteaga-Henriquez 1, Bianka Burger 2, Elif Weidinger 3, Laura Grosse 4, Natalie Moll 5, Gregor Schuetze 5, Markus Schwarz 5, Annemarie Wijkhuijs 6, Gommaar Op de Beeck 7, Raf Berghmans 7, Marjan A Versnel 6, Volker Arolt 8, Norbert Müller 2, Hemmo A Drexhage 6
Publié dans:
Activation and deactivation steps in the tryptophan breakdown pathway in major depressive disorder: A link to the monocyte inflammatory state of patients, 2021, ISSN 0278-5846
Éditeur:
Elsevier BV
DOI:
10.1016/j.pnpbp.2020.110226
Auteurs:
Madsen KB, Momen NC, Petersen LV, Plana-Ripoll O, Haarman BCM, Drexhage H, Mortensen PB, McGrath JJ, Munk-Olsen T
Publié dans:
Bidirectional associations between treatment-resistant depression and general medical conditions, 2021, ISSN 0924-977X
Éditeur:
Elsevier BV
DOI:
10.1016/j.euroneuro.2021.04.021
Auteurs:
Manusama OR, van Beveren NJM, van Hagen PM, Drexhage HA, Dalm VASH
Publié dans:
Psychological Symptoms in Primary Immunodeficiencies: a Common Comorbidity?, 2022, ISSN 0271-9142
Éditeur:
Kluwer Academic/Plenum Publishers
DOI:
10.1007/s10875-022-01207-7
Auteurs:
Mareike Aichholzer 1, Shiral S Gangadin 2 3, Iris E C Sommer 2 3, Annemarie Wijkhuis 4, Lot D de Witte 5, René S Kahn 5, Sabine Bahn 6, Hemmo A Drexhage 4, Carmen Schiweck 1
Publié dans:
Brain Behaviour Immun Health 2022, Numéro 2022, 2022, ISSN 2666-3546
Éditeur:
Elsevier Inc.
DOI:
10.1016/j.bbih.2022.100551
Auteurs:
Kathrine Bang Madsen, Liselotte Vogdrup Petersen, Oleguer Plana-Ripoll, Katherine L. Musliner, Jean-Christophe Philippe Debost, Frederikke Hordam Gronemann, Preben Bo Mortensen, Trine Munk-Olsen
Publié dans:
Therapeutic Advances in Psychopharmacology, Numéro 10, 2020, Page(s) 204512532097379, ISSN 2045-1253
Éditeur:
Katherine Bang Madsen
DOI:
10.1177/2045125320973791
Auteurs:
Branchi I, Poggini S, Capuron L, Benedetti F, Poletti S, Tamouza R, Drexhage HA, Penninx BWJH, Pariante CM; European College of Neuropsychopharmacology (ECNP) ImmunoNeuroPsychiatry Thematic Working Group and Marion Leboyer
Publié dans:
Brain-immune crosstalk in the treatment of major depressive disorder., 2021, ISSN 0924-977X
Éditeur:
Elsevier BV
DOI:
10.1016/j.euroneuro.2020.11.016
Auteurs:
Jakub Tomasik 1, Carmen Schiweck 2, Hemmo A Drexhage 3
Publié dans:
Biologic Psychiatry, Numéro 2023, 2023, ISSN 1873-2402
Éditeur:
Elsevier
DOI:
10.1016/j.biopsych.2022.10.017
Auteurs:
Ioannou M, Foiselle M, Mallet J, Stam EL, Godin O, Dubertret C, Terro E, Sommer IEC, Haarman BCM, Leboyer M, Schoevers RA.
Publié dans:
Towards precision medicine: What are the stratification hypotheses to identify homogeneous inflammatory subgroups, 2021, ISSN 0924-977X
Éditeur:
Elsevier BV
DOI:
10.1016/j.euroneuro.2020.11.001
Auteurs:
Serra I, Manusama OR, Fabian M.P. Kaiser FMP, Floriano II
Publié dans:
Activated PI3Kδ syndrome, an immunodeficiency disorder, leads to sensorimotor deficits recapitulated in a murine model – ScienceDirect, 2021, ISSN 2666-3546
Éditeur:
Elsevier Inc
DOI:
10.1016/j.bbih.2021.100377
Auteurs:
Frederikke Hørdam Gronemann, Thomas Lund, Louise Lindholdt, Kathrine Bang Madsen, Martin Balslev Jørgensen, Merete Nordentoft & Merete Osler
Publié dans:
Treatment-resistant depression and labor market affiliation in the Danish welfare society: a register-based study, 2022, ISSN 0933-7954
Éditeur:
Dr. Dietrich Steinkopff Verlag
DOI:
10.1007/s00127-022-02243-9
Auteurs:
Moss CS, Drexhage HA, Rutten S.
Publié dans:
2022
Éditeur:
Bohn Stafleu, van Loghum
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