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Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment

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Publications

Inflammatory bone marrow microenvironment

Author(s): Nils B. Leimkühler, Rebekka K. Schneider
Published in: Hematology, Issue 2019/1, 2019, Page(s) 294-302, ISSN 1520-4391
DOI: 10.1182/hematology.2019000045

Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN

Author(s): Helene Gleitz, Aurelien J.F. Dugourd, Nils Bastian Leimkühler, Inge A.M Snoeren, Stijn N.R. Fuchs, Sylvia Menzel, Susanne Ziegler, Nicolaus Kroeger, Ioanna Triviai, Guntram Büsche, Hans Kreipe, Bella Banjanin, Jessica Pritchard, Remco Hoogenboezem, Eric Bindels, Neele Schumacher, Stefan Rose-John, Shannon Elf, Julio Saez-Rodriguez, Rafael Kramann, Rebekka K Schneider
Published in: Blood, 2020, ISSN 0006-4971
DOI: 10.1182/blood.2019004095

Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis

Author(s): Hélène FE Gleitz, Rafael Kramann, Rebekka K Schneider
Published in: The Journal of Pathology, Issue 245/2, 2018, Page(s) 138-146, ISSN 0022-3417
DOI: 10.1002/path.5078

Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome

Author(s): Flavia Ribezzo, Inge A. M. Snoeren, Susanne Ziegler, Jacques Stoelben, Patricia A. Olofsen, Almira Henic, Monica Ventura Ferreira, Si Chen, Ursula S. A. Stalmann, Guntram Buesche, Remco M. Hoogenboezem, Rafael Kramann, Uwe Platzbecker, Marc H. G. P. Raaijmakers, Benjamin L. Ebert, Rebekka K. Schneider
Published in: Leukemia, Issue 33/7, 2019, Page(s) 1759-1772, ISSN 0887-6924
DOI: 10.1038/s41375-018-0350-3

Dissecting the Functional Reprogramming of the Microenvironment in Bone Marrow Fibrosis at the Single Cell Level

Author(s): Nils B. Leimkühler, Li Ronghui, Hélène F.E. Gleitz, Inge A. M. Snoeren, Stijn N.R. Fuchs, Christoph Kuppe, Ursula S. A. Stalmann, Guntram Buesche, Hans Kreipe, Ines Gütgemann, Philippe Krebs, Yara Banz, Peter Boor, Evelyn Wing-Ying Tai, Tim H. Brümmendorf, Steffen Koschmieder, Martina Crysandt, Eric Bindels, Rafael Kramann, Ivan G. Costa, Rebekka K. Schneider
Published in: SSRN Electronic Journal, 2020, ISSN 1556-5068
DOI: 10.2139/ssrn.3493957