Dissecting the cellular and molecular dynamics of bone marrow fibrosis for improved diagnostics and treatment

Informazioni relative al progetto

deFIBER

ID dell’accordo di sovvenzione: 757339

DOI 10.3030/757339

Progetto chiuso

Data della firma CE 28 Settembre 2017

Data di avvio 1 Gennaio 2018

Data di completamento 31 Dicembre 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 498 544,00

Contributo UE € 1 498 544,00

Coordinato da

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

Pubblicazioni

Peer reviewed articles (4)

Inflammatory bone marrow microenvironment

Autori: Nils B. Leimkühler, Rebekka K. Schneider
Pubblicato in: Hematology, Numero 2019/1, 2019, Pagina/e 294-302, ISSN 1520-4391
Editore: American Society of Hematology
DOI: 10.1182/hematology.2019000045

Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN

Autori: Helene Gleitz, Aurelien J.F. Dugourd, Nils Bastian Leimkühler, Inge A.M Snoeren, Stijn N.R. Fuchs, Sylvia Menzel, Susanne Ziegler, Nicolaus Kroeger, Ioanna Triviai, Guntram Büsche, Hans Kreipe, Bella Banjanin, Jessica Pritchard, Remco Hoogenboezem, Eric Bindels, Neele Schumacher, Stefan Rose-John, Shannon Elf, Julio Saez-Rodriguez, Rafael Kramann, Rebekka K Schneider
Pubblicato in: Blood, 2020, ISSN 0006-4971
Editore: American Society of Hematology
DOI: 10.1182/blood.2019004095

Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis

Autori: Hélène FE Gleitz, Rafael Kramann, Rebekka K Schneider
Pubblicato in: The Journal of Pathology, Numero 245/2, 2018, Pagina/e 138-146, ISSN 0022-3417
Editore: John Wiley & Sons Inc.
DOI: 10.1002/path.5078

Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome

Autori: Flavia Ribezzo, Inge A. M. Snoeren, Susanne Ziegler, Jacques Stoelben, Patricia A. Olofsen, Almira Henic, Monica Ventura Ferreira, Si Chen, Ursula S. A. Stalmann, Guntram Buesche, Remco M. Hoogenboezem, Rafael Kramann, Uwe Platzbecker, Marc H. G. P. Raaijmakers, Benjamin L. Ebert, Rebekka K. Schneider
Pubblicato in: Leukemia, Numero 33/7, 2019, Pagina/e 1759-1772, ISSN 0887-6924
Editore: Nature Publishing Group
DOI: 10.1038/s41375-018-0350-3

Non-peer reviewed articles (1)

Dissecting the Functional Reprogramming of the Microenvironment in Bone Marrow Fibrosis at the Single Cell Level

Autori: Nils B. Leimkühler, Li Ronghui, Hélène F.E. Gleitz, Inge A. M. Snoeren, Stijn N.R. Fuchs, Christoph Kuppe, Ursula S. A. Stalmann, Guntram Buesche, Hans Kreipe, Ines Gütgemann, Philippe Krebs, Yara Banz, Peter Boor, Evelyn Wing-Ying Tai, Tim H. Brümmendorf, Steffen Koschmieder, Martina Crysandt, Eric Bindels, Rafael Kramann, Ivan G. Costa, Rebekka K. Schneider
Pubblicato in: SSRN Electronic Journal, 2020, ISSN 1556-5068
Editore: Sneak Peek Cell Press
DOI: 10.2139/ssrn.3493957