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A combined in vitro and in vivo approach to dissect biochemical network evolution.


Evolved interactions stabilize many coexisting phases in multicomponent liquids

Author(s): David Zwicker and Liedewij Laan
Published in: PNAS, 2022, ISSN 1091-6490
Publisher: National Academy of Science
DOI: 10.1073/pnas.2201250119

Predicting evolution using regulatory architecture

Author(s): Philippe Nghe, Marjon de Vos, Enzo Kingma, Manjunatha Kogenaru, Frank Poelwijk, Liedewij Laan, Sander Tans
Published in: Annu Rev Biophys, 2020, ISSN 1936-1238
Publisher: Annual Review
DOI: 10.1146/annurev-biophys-070317-032939

The Path towards Predicting Evolution as Illustrated in Yeast Cell Polarity

Author(s): Werner Daalman, Els Sweep, Liedewij Laan
Published in: Cells, Issue 9/12, 2020, Page(s) 2534, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells9122534

Complexity and self-organization in the evolution of cell polarization

Author(s): Marieke Glazenburg and Liedewij Laan
Published in: Journal of Cell Science, 2023, ISSN 1477-9137
Publisher: Company of Biologists
DOI: 10.1242/jcs.259639

A tractable physical model for the yeast polarity predicts epistasis and fitness

Author(s): Werner Karl-Gustav Daalman, Els Sweep, and Liedewij Laan
Published in: Phil. Trans. R. Soc. B, 2023, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2022.0044

A guide to the in vitro reconstitution of Cdc42 GTPase activity and its regulation

Author(s): Sophie Tschirpke, Frank van Opstal, Ramon van der Valk , Daalman Werner K-G., Liedewij Laan
Published in: 2023
Publisher: na
DOI: 10.1101/2023.04.24.538075

Adaptability and evolution of the cell polarization machinery in budding yeast

Author(s): Fridtjof Brauns, Leila M. Iñigo de la Cruz, Werner K.-G. Daalman, Ilse de Bruin, Jacob Halatek, Liedewij Laan, Erwin Frey
Published in: 2020
Publisher: BiorXiv
DOI: 10.1101/2020.09.09.290510

Pleiotropy allows recovery of phenotypic plasticity in constant environments

Author(s): Enzo Kingma, Eveline T. Diepeveen, Leila Iñigo de la Cruz, Liedewij Laan
Published in: 2020
Publisher: BiorXiv
DOI: 10.1101/2020.06.02.123208

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