Lipid asymmetry: a cellular battery?

Project Information

ASYMMEM

Grant agreement ID: 758334

DOI

10.3030/758334

Project closed

EC signature date 28 September 2017

Start date 1 January 2018

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Live-cell lipid biochemistry reveals a role of diacylglycerol side-chain composition for cellular lipid dynamics and protein affinities

Author(s): Milena Schuhmacher, Andreas T. Grasskamp, Pavel Barahtjan, Nicolai Wagner, Benoit Lombardot, Jan S. Schuhmacher, Pia Sala, Annett Lohmann, Ian Henry, Andrej Shevchenko, Ünal Coskun, Alexander M. Walter, André Nadler
Published in: Proceedings of the National Academy of Sciences, Issue 117/14, 2020, Page(s) 7729-7738, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1912684117

Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics

Author(s): Kai Schuhmann, HongKee Moon, Henrik Thomas, Jacobo Miranda Ackerman, Michael Groessl, Nicolai Wagner, Markus Kellmann, Ian Henry, André Nadler, Andrej Shevchenko
Published in: Analytical Chemistry, Issue 91/18, 2019, Page(s) 12085-12093, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.9b03270

A Coumarin Triflate Reagent Enables One‐Step Synthesis of Photo‐Caged Lipid Metabolites for Studying Cell Signaling

Author(s): Nicolai Wagner, Milena Schuhmacher, Annett Lohmann, André Nadler
Published in: Chemistry – A European Journal, Issue 25/68, 2019, Page(s) 15483-15487, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201903909

A Click Cage: Organelle‐Specific Uncaging of Lipid Messengers

Author(s): Nicolai Wagner, Milena Stephan, Doris Höglinger, André Nadler
Published in: Angewandte Chemie International Edition, Issue 57/40, 2018, Page(s) 13339-13343, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201807497

Other (5)

Caged lipid probes for controlling lipid levels on subcellular scales

Author(s): Cristina Jiménez-López; André Nadler
Published in: Current Opinion in Chemical Biology, 2023
Publisher: Elsevier
DOI: 10.1016/j.cbpa.2022.102234

Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse

Author(s): Jane C Stinchcombe, Yukako Asano, Christopher J G Kaufman, Kristin Böhlig, Christopher J Peddie, Lucy M Collinson, André Nadler, Gillian M Griffiths
Published in: Science, 2023
Publisher: Science
DOI: 10.1126/science.abp8933

The Road to Quantitative Lipid Biochemistry in Living Cells

Author(s): Juan M. Iglesias-Artola; André Nadler
Published in: American Chemical Society, 2023
Publisher: ACS Publications
DOI: 10.1021/acs.accounts.2c00804

Adressing lipid structural diversity in signalling: Photochemcial probes for live-cell lipid biochemistry (reprint)

Author(s): Milena Schuhmacher, Andreas T. Grasskamp, Nicolai Wagner, Benoit Lomardot, Jan. S. Schuhmacher, Pia Sala, Annett Lohmann, Ian Henry, Andrej Shevchenko, Ünal Coskun, Alexander Walter, André Nadler
Published in: BioRxiv, 2019
Publisher: Preprint from bioRxiv
DOI: 10.1101/711291

Quantifying single cell lipid signaling kinetics after photo-stimulation

Author(s): David T. Gonzales; Milena Schuhmacher; H. Mathilda Lennartz; Juan M. Iglesias-Artola; Sascha M. Kuhn; Pavel Barahtjan; Christoph Zechner; André Nadler
Published in: Biophysical Journal, 2023
Publisher: CellPress
DOI: 10.1016/j.bpj.2023.11.013