REsponsive theranostic nanosystems for Advanced Cancer Treatment

Project Information

REACT

Grant agreement ID: 758887

DOI 10.3030/758887

Project closed

EC signature date 13 August 2018

Start date 1 January 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 498 345,77

EU contribution € 1 498 345,77

Coordinated by

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

MRI-based sensing of pH-responsive content release from mesoporous silica nanoparticles

Author(s): Mirjana Mundžić, Jelena Lazović, Minja Mladenović, Aleksandra Pavlović, Amelia Ultimo, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez, Maria Jose Santos-Martinez, Nikola Ž. Knežević
Published in: Journal of Sol-Gel Science and Technology, Issue 111, 2024, Page(s) 95-105, ISSN 0928-0707
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10971-024-06422-9

Chlorotoxin-functionalized mesoporous silica nanoparticles for pH-responsive paclitaxel delivery to Glioblastoma multiforme

Author(s): Mirjana Mundžić, Amelia Ultimo, Minja Mladenović, Aleksandra Pavlović, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez, Maria Jose Santos-Martinez, Nikola Ž. Knežević
Published in: Heliyon, Issue 11, 2025, Page(s) e41151, ISSN 2405-8440
Publisher: Elsevier
DOI: 10.1016/j.heliyon.2024.e41151

Advanced mesoporous silica nanocarriers in cancer theranostics and gene editing applications

Author(s): Kristina Živojević, Minja Mladenović, Mila Djisalov, Mirjana Mundzic, Eduardo Ruiz-Hernandez, Ivana Gadjanski, Nikola Ž. Knežević
Published in: Journal of Controlled Release, Issue 337, 2021, Page(s) 193-211, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2021.07.029

In Situ-Forming Gels Loaded with Stimuli-Responsive Gated Mesoporous Silica Nanoparticles for Local Sustained Drug Delivery

Author(s): Cristina de la Torre, Carmen Coll, Amelia Ultimo, Félix Sancenón, Ramón Martínez-Máñez, Eduardo Ruiz-Hernández
Published in: Pharmaceutics, Issue 15, 2025, Page(s) 1071, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15041071

Biocompatible copolymer formulations to treat glioblastoma multiforme

Author(s): Luiza C.S. Erthal, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez
Published in: Acta Biomaterialia, Issue 121, 2021, Page(s) 89-102, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2020.11.030

Intranasal Polymeric and Lipid-Based Nanocarriers for CNS Drug Delivery

Author(s): Rebecca Maher, Almudena Moreno-Borrallo, Dhruvi Jindal, Binh T. Mai, Eduardo Ruiz-Hernandez, Andrew Harkin
Published in: Pharmaceutics, Issue 15, 2023, Page(s) 746, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15030746

Amino-Functionalized Mesoporous Silica Nanoparticle-Encapsulated Octahedral Organoruthenium Complex as an Efficient Platform for Combatting Cancer

Author(s): Marina Martínez-Carmona, Quy P. Ho, Jérémy Morand, Ana García, Enrique Ortega, Luiza C. S. Erthal, Eduardo Ruiz-Hernandez, M. Dolores Santana, José Ruiz, Maria Vallet-Regí, Yurii K. Gun’ko
Published in: Inorganic Chemistry, Issue 59/14, 2020, Page(s) 10275-10284, ISSN 0020-1669
Publisher: American Chemical Society
DOI: 10.1021/acs.inorgchem.0c01436

Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme

Author(s): Luiza C. S. Erthal, Yang Shi, Kieron J. Sweeney, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez
Published in: Scientific Reports, Issue 13, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-32257-5

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery

Author(s): Amelia Ultimo, Mar Orzaez, Maria J. Santos-Martinez, Ramón Martínez-Máñez, María D. Marcos, Félix Sancenón, Eduardo Ruiz-Hernández
Published in: International Journal of Molecular Sciences, Issue 24, 2025, Page(s) 2753, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032753

Other (1)

pH-responsive Nanosystems for Targeted Drug Delivery to Glioblastoma Multiforme and MRI-facilitated Monitoring of Content Release

Author(s): Mirjana Mundžić, Amelia Ultimo, Jelena Lazović, Minja Mladenović, Aleksandra Pavlović, Oliviero Gobbo, Eduardo Ruiz-Hernandez, Maria Santos-Martinez, Nikola Knežević
Published in: Research Square, 2023
Publisher: Research Square Platform LLC
DOI: 10.21203/rs.3.rs-3709910/v1