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Targeting the Oncogenic Function of Myc in vivo

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Publications

Targeting MYC Proteins for Tumor Therapy

Author(s): Elmar Wolf, Martin Eilers
Published in: Annual Review of Cancer Biology, Issue 4/1, 2020, Page(s) 61-75, ISSN 2472-3428
DOI: 10.1146/annurev-cancerbio-030518-055826

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase

Author(s): Bikash Adhikari, Jelena Bozilovic, Mathias Diebold, Jessica Denise Schwarz, Julia Hofstetter, Martin Schröder, Marek Wanior, Ashwin Narain, Markus Vogt, Nevenka Dudvarski Stankovic, Apoorva Baluapuri, Lars Schönemann, Lorenz Eing, Pranjali Bhandare, Bernhard Kuster, Andreas Schlosser, Stephanie Heinzlmeir, Christoph Sotriffer, Stefan Knapp, Elmar Wolf
Published in: Nature Chemical Biology, Issue 16/11, 2020, Page(s) 1179-1188, ISSN 1552-4450
DOI: 10.1038/s41589-020-00652-y

Target gene-independent functions of MYC oncoproteins

Author(s): Apoorva Baluapuri, Elmar Wolf, Martin Eilers
Published in: Nature Reviews Molecular Cell Biology, Issue 21/5, 2020, Page(s) 255-267, ISSN 1471-0072
DOI: 10.1038/s41580-020-0215-2

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

Author(s): Apoorva Baluapuri, Julia Hofstetter, Nevenka Dudvarski Stankovic, Theresa Endres, Pranjali Bhandare, Seychelle Monique Vos, Bikash Adhikari, Jessica Denise Schwarz, Ashwin Narain, Markus Vogt, Shuang-Yan Wang, Robert Düster, Lisa Anna Jung, Jens Thorsten Vanselow, Armin Wiegering, Matthias Geyer, Hans Michael Maric, Peter Gallant, Susanne Walz, Andreas Schlosser, Patrick Cramer, Martin Eilers, El
Published in: Molecular Cell, Issue 74/4, 2019, Page(s) 674-687.e11, ISSN 1097-2765
DOI: 10.1016/j.molcel.2019.02.031