Molecular mechanisms of interferon-induced antiviral restriction and signalling

Project Information

ANTIViR

Grant agreement ID: 759226

DOI

10.3030/759226

Project closed

EC signature date 14 November 2017

Start date 1 December 2017

End date 30 November 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 793,77

EU contribution

€ 1 499 793,77

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs

Author(s): Antoine Rebendenne, Priyanka Roy, Boris Bonaventure, Ana Luiza Chaves Valadão, Lowiese Desmarets, Mary Arnaud-Arnould, Yves Rouillé, Marine Tauziet, Donatella Giovannini, Jawida Touhami, Yenarae Lee, Peter DeWeirdt, Mudra Hegde, Serge Urbach, Khadija El Koulali, Francisco Garcia de Gracia, Joe McKellar, Jean Dubuisson, Mélanie Wencker, Sandrine Belouzard, Olivier Moncorgé, John G. Doench and C
Published in: Nature Genetics, 2022, ISSN 1546-1718
Publisher: NPG
DOI: 10.1038/s41588-022-01110-2

Crystal structure of the TLDc domain of human NCOA7-AS.

Author(s): Mary Arnaud-Arnould; Marine Tauziet; Olivier Moncorgé; Caroline Goujon; Mickaël Blaise
Published in: Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS, Issue 2, 2021, ISSN 2053-230X
Publisher: John Wiley and Sons Ltd
DOI: 10.1107/s2053230x21006853

DExH/D-box helicases at the frontline of intrinsic and innate immunity against viral infections

Author(s): Boris Bonaventure, Caroline Goujon
Published in: Journal of General Virology, 2022, ISSN 1465-2099
Publisher: Microbiology Society
DOI: 10.1099/jgv.0.001766

Clash of the titans: interferons and SARS-CoV-2

Author(s): Nolwenn Jouvenet, Caroline Goujon, Arinjay Banerjee
Published in: Trends in Immunology, 2021, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2021.10.009

Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells

Author(s): Rémi Planès, Miriam Pinilla, Karin Santoni, Audrey Hessel, Charlotte Passemar, Kenneth Lay, Perrine Paillette, Ana-Luiza Chaves Valadão, Kim Samirah Robinson, Paul Bastard, Nathaniel Lam, Ricardo Fadrique, Ida Rossi, David Pericat, Salimata Bagayoko, Stephen Adonai Leon-Icaza, Yoann Rombouts, Eric Perouzel, Michèle Tiraby, COVID Human Genetic Effort; Qian Zhang, Pietro Cicuta, Emmanuelle Jouan
Published in: Molecular Cell, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.04.033

The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry

Author(s): Tomas Doyle, Olivier Moncorgé, Boris Bonaventure, Darja Pollpeter, Marion Lussignol, Marine Tauziet, Luis Apolonia, Maria-Teresa Catanese, Caroline Goujon, Michael H. Malim
Published in: Nature Microbiology, Issue 3/12, 2018, Page(s) 1369-1376, ISSN 2058-5276
Publisher: Springer Nature
DOI: 10.1038/s41564-018-0273-9

Mammalian and Avian Host Cell Influenza A Restriction Factors

Author(s): Joe McKellar, Antoine Rebendenne, Mélanie Wencker, Olivier Moncorgé, Caroline Goujon
Published in: Viruses, 2021, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030522

The <scp>DEAD</scp> box <scp>RNA</scp> helicase <scp>DDX42</scp> is an intrinsic inhibitor of positive‐strand <scp>RNA</scp> viruses

Author(s): Boris Bonaventure; Antoine Rebendenne; Ana Luiza Chaves Valadão; Mary Arnaud‐Arnould; Ségolène Gracias; Francisco Garcia de Gracia; Joe McKellar; Emmanuel Labaronne; Marine Tauziet; Valérie Vivet‐Boudou; Eric Bernard; Laurence Briant; Nathalie Gros; Wassila Djilli; Valérie Courgnaud; Hugues Parrinello; Stéphanie Rialle; Mickaël Blaise; Laurent Lacroix; Marc Lavigne; Jean‐Christophe Pa
Published in: EMBO reports, 2022, ISSN 1469-3178
Publisher: Wiley
DOI: 10.15252/embr.202154061

SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells

Author(s): Antoine Rebendenne, Ana Luiza Chaves Valadao, Marine Tauziet, Ghizlane Maarifi, Boris Bonaventure, Joe McKellar, Sébastien Nisole, Mary Arnaud-Arnould, Olivier Moncorgé, Caroline Goujon
Published in: Journal of Virology, 2021, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.02415-20

An evolutionarily conserved N-terminal leucine is essential for MX1 GTPase antiviral activity against different families of RNA viruses

Author(s): Joe McKellar, Mary Arnaud-Arnould, Laurent Chaloin, Marine Tauziet, Charlotte Arpin-André, Oriane Pourcelot, Mickaël Blaise, Olivier Moncorgé, and Caroline Goujon
Published in: Journal of Biological Chemistry, 2023, ISSN 1083-351X
Publisher: American Society for Biochemistry and Molecular Biology, Inc.
DOI: 10.1016/j.jbc.2022.102747

Other (1)

Human MX1 induces the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

Author(s): Joe McKellar, Francisco García de Gracia, Corentin Aubé, Ana Luiza Chaves Valadão, Marine Tauziet, Mary Arnaud-Arnould, Antoine Rebendenne, Aymeric Neyret, Emmanuel Labaronne, Emiliano P. Ricci, Bénédicte Delaval, Raphael Gaudin, Nadia Naffakh, Sarah Gallois-Montbrun, Olivier Moncorgé, Caroline Goujon
Published in: bioRxiv, 2024
Publisher: bioRxiv