Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues - | STRATO | Project | Results | H2020 | CORDIS

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Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation

Auteurs: Ulrike Meyer-Lindemann; Ulrike Meyer-Lindemann; Carina Mauersberger; Carina Mauersberger; Anna-Christina Schmidt; Anna-Christina Schmidt; Aldo Moggio; Julia Hinterdobler; Julia Hinterdobler; Xinghai Li; David Khangholi; David Khangholi; Jan Hettwer; Jan Hettwer; Christian Gräßer; Christian Gräßer; Alexander Dutsch; Alexander Dutsch; Heribert Schunkert; Heribert Schunkert; Thorsten Kessler; Tho
Publié dans: Frontiers in immunology, Numéro 13/2022, 2022, ISSN 1664-3224
Éditeur: Frontiers in immunology
DOI: 10.3389/fimmu.2022.898690

The Impact of Exercise on Immunity, Metabolism, and Atherosclerosis

Auteurs: Ulrike Meyer-Lindemann; Aldo Moggio; Alexander Dutsch; Thorsten Kessler; Hendrik B. Sager
Publié dans: International Journal of Molecular Sciences, Numéro Vol 24, Iss 4, 2023, Page(s) 3394, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24043394

Immune cell-based cardiovascular risk assessment: spotlight on the neutrophil-lymphocyte ratio

Auteurs: Sager HB, Koenig W.
Publié dans: Eur Heart J., Numéro 2021 Mar, 2021, Page(s) 904-906, ISSN 0195-668X
Éditeur: Oxford University Press
DOI: 10.1093/eurheartj/ehaa1104

Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction

Auteurs: Moggio A, Schunkert H, Kessler T, Sager HB.
Publié dans: International Journal of Molecular Sciences, Numéro 23, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232415814

Functional investigation of the coronary artery disease gene SVEP1

Auteurs: Michael J. Winkler; Philipp Müller; Amin M. Sharifi; Jana Wobst; Hanna Winter; Michal Mokry; Lijiang Ma; Sander W. van der Laan; Shichao Pang; Benedikt Miritsch; Julia Hinterdobler; Julia Werner; Barbara Stiller; Ulrich Güldener; Tom R. Webb; Folkert W. Asselbergs; Folkert W. Asselbergs; Johan L.M. Björkegren; Johan L.M. Björkegren; Johan L.M. Björkegren; Lars Maegdefessel; Heribert Schunkert
Publié dans: Basic Research in Cardiology, Numéro 115, 2020, ISSN 0300-8428
Éditeur: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-020-00828-6

Where the Action Is—Leukocyte Recruitment in Atherosclerosis

Auteurs: Carina Mauersberger; Carina Mauersberger; Julia Hinterdobler; Julia Hinterdobler; Heribert Schunkert; Heribert Schunkert; Thorsten Kessler; Thorsten Kessler; Hendrik B. Sager; Hendrik B. Sager
Publié dans: Frontiers in Cardiovascular Medicine, Numéro Vol 8 (2022), 2022, ISSN 2297-055X
Éditeur: Lausanne: Frontiers Media S.A., 2014
DOI: 10.3389/fcvm.2021.813984

Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis

Auteurs: Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB.
Publié dans: Cardiovascular Research, Numéro Volume 118, Numéro 13, 2022, ISSN 0008-6363
Éditeur: Elsevier BV
DOI: 10.1093/cvr/cvab337

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation

Auteurs: Mauersberger, Carina; Sager, Hendrik B; Wobst, Jana; Dang, Tan An; Lambrecht, Laura; Koplev, Simon; Stroth, Marlène; Bettaga, Noomen; Schlossmann, Jens; Wunder, Frank; Friebe, Andreas; Björkegren, Johan LM; Dietz, Lisa; Maas, Sanne L; Van Der Vorst, Emiel PC; Sandner, Peter; Soehnlein, Oliver; Schunkert, Heribert; Kessler, Thorsten
Publié dans: Nature Cardiovascular Research, Numéro 12/2022, 2022, ISSN 2731-0590
Éditeur: Nature Cardiovascular Research (Nat Cardiovasc Res)
DOI: 10.1038/s44161-022-00175-w

Acute inflammation and long-term cardiovascular risk: Identifying an unrecognised vulnerable gap

Auteurs: Hendrik B Sager, Wolfgang Koenig
Publié dans: European Journal of Preventive Cardiology, Numéro 24/18, 2017, Page(s) 1956-1957, ISSN 2047-4873
Éditeur: SAGE Publications Ltd
DOI: 10.1177/2047487317736869

Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction

Auteurs: Hendrik B. Sager, Oliver Husser, Sabine Steffens, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Gjin Ndrepepa, Thorsten Kessler
Publié dans: Journal of Translational Medicine, Numéro 17/1, 2019, ISSN 1479-5876
Éditeur: BioMed Central
DOI: 10.1186/s12967-019-1934-z

Management of hypercalcaemia-induced heart failure using mechanical circulatory support

Auteurs: Katharina Knoll, Volkhard Kurowski, Heribert Schunkert, Hendrik B Sager
Publié dans: European Journal of Cardio-Thoracic Surgery, Numéro 54/4, 2018, Page(s) 784-785, ISSN 1010-7940
Éditeur: Elsevier BV
DOI: 10.1093/ejcts/ezy139

Impact of Acute and Chronic Psychosocial Stress on Vascular Inflammation

Auteurs: Hinterdobler J, Schunkert H, Kessler T, Sager HB.
Publié dans: Antioxid Redox Signal, Numéro Volume 35, Numéro 18, 2021, ISSN 1523-0864
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2021.0153

Association of In-Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long-Term Mortality in Patients With Acute ST-Segment-Elevation Myocardial Infarction

Auteurs: Dutsch A, Graesser C, Voll F, Novacek S, Eggerstedt R, Armbruster NL, Laugwitz KL, Cassese S, Schunkert H, Ndrepepa G, Kastrati A, Kessler T, Sager HB.
Publié dans: Journal of the American Heart Association, Numéro 2022 Sep 6, 2022, ISSN 2047-9980
Éditeur: Wiley-Blackwell
DOI: 10.1161/jaha.121.024857

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.

Auteurs: Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB.
Publié dans: European Heart Journal, Numéro Volume 42, Numéro 39, 2021, ISSN 0195-668X
Éditeur: Oxford University Press
DOI: 10.1093/eurheartj/ehab371

Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues -

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