Stress as a modifier of atherosclerosis - Novel mechanistic insights and therapeutic avenues -

Informazioni relative al progetto

STRATO

ID dell’accordo di sovvenzione: 759272

DOI

10.3030/759272

Progetto chiuso

Data della firma CE 19 Dicembre 2017

Data di avvio 1 Febbraio 2018

Data di completamento 31 Gennaio 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 477 680,00

Contributo UE

€ 1 477 680,00

Coordinato da

DEUTSCHES HERZZENTRUM MUNCHEN
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (1)

Data Management Plan

Pubblicazioni

Peer reviewed articles (14)

Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation

Autori: Ulrike Meyer-Lindemann; Ulrike Meyer-Lindemann; Carina Mauersberger; Carina Mauersberger; Anna-Christina Schmidt; Anna-Christina Schmidt; Aldo Moggio; Julia Hinterdobler; Julia Hinterdobler; Xinghai Li; David Khangholi; David Khangholi; Jan Hettwer; Jan Hettwer; Christian Gräßer; Christian Gräßer; Alexander Dutsch; Alexander Dutsch; Heribert Schunkert; Heribert Schunkert; Thorsten Kessler; Tho
Pubblicato in: Frontiers in immunology, Numero 13/2022, 2022, ISSN 1664-3224
Editore: Frontiers in immunology
DOI: 10.3389/fimmu.2022.898690

The Impact of Exercise on Immunity, Metabolism, and Atherosclerosis

Autori: Ulrike Meyer-Lindemann; Aldo Moggio; Alexander Dutsch; Thorsten Kessler; Hendrik B. Sager
Pubblicato in: International Journal of Molecular Sciences, Numero Vol 24, Iss 4, 2023, Pagina/e 3394, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24043394

Immune cell-based cardiovascular risk assessment: spotlight on the neutrophil-lymphocyte ratio

Autori: Sager HB, Koenig W.
Pubblicato in: Eur Heart J., Numero 2021 Mar, 2021, Pagina/e 904-906, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehaa1104

Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction

Autori: Moggio A, Schunkert H, Kessler T, Sager HB.
Pubblicato in: International Journal of Molecular Sciences, Numero 23, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232415814

Functional investigation of the coronary artery disease gene SVEP1

Autori: Michael J. Winkler; Philipp Müller; Amin M. Sharifi; Jana Wobst; Hanna Winter; Michal Mokry; Lijiang Ma; Sander W. van der Laan; Shichao Pang; Benedikt Miritsch; Julia Hinterdobler; Julia Werner; Barbara Stiller; Ulrich Güldener; Tom R. Webb; Folkert W. Asselbergs; Folkert W. Asselbergs; Johan L.M. Björkegren; Johan L.M. Björkegren; Johan L.M. Björkegren; Lars Maegdefessel; Heribert Schunkert
Pubblicato in: Basic Research in Cardiology, Numero 115, 2020, ISSN 0300-8428
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-020-00828-6

Where the Action Is—Leukocyte Recruitment in Atherosclerosis

Autori: Carina Mauersberger; Carina Mauersberger; Julia Hinterdobler; Julia Hinterdobler; Heribert Schunkert; Heribert Schunkert; Thorsten Kessler; Thorsten Kessler; Hendrik B. Sager; Hendrik B. Sager
Pubblicato in: Frontiers in Cardiovascular Medicine, Numero Vol 8 (2022), 2022, ISSN 2297-055X
Editore: Lausanne: Frontiers Media S.A., 2014
DOI: 10.3389/fcvm.2021.813984

Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis

Autori: Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB.
Pubblicato in: Cardiovascular Research, Numero Volume 118, Numero 13, 2022, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab337

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation

Autori: Mauersberger, Carina; Sager, Hendrik B; Wobst, Jana; Dang, Tan An; Lambrecht, Laura; Koplev, Simon; Stroth, Marlène; Bettaga, Noomen; Schlossmann, Jens; Wunder, Frank; Friebe, Andreas; Björkegren, Johan LM; Dietz, Lisa; Maas, Sanne L; Van Der Vorst, Emiel PC; Sandner, Peter; Soehnlein, Oliver; Schunkert, Heribert; Kessler, Thorsten
Pubblicato in: Nature Cardiovascular Research, Numero 12/2022, 2022, ISSN 2731-0590
Editore: Nature Cardiovascular Research (Nat Cardiovasc Res)
DOI: 10.1038/s44161-022-00175-w

Acute inflammation and long-term cardiovascular risk: Identifying an unrecognised vulnerable gap

Autori: Hendrik B Sager, Wolfgang Koenig
Pubblicato in: European Journal of Preventive Cardiology, Numero 24/18, 2017, Pagina/e 1956-1957, ISSN 2047-4873
Editore: SAGE Publications Ltd
DOI: 10.1177/2047487317736869

Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction

Autori: Hendrik B. Sager, Oliver Husser, Sabine Steffens, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Gjin Ndrepepa, Thorsten Kessler
Pubblicato in: Journal of Translational Medicine, Numero 17/1, 2019, ISSN 1479-5876
Editore: BioMed Central
DOI: 10.1186/s12967-019-1934-z

Management of hypercalcaemia-induced heart failure using mechanical circulatory support

Autori: Katharina Knoll, Volkhard Kurowski, Heribert Schunkert, Hendrik B Sager
Pubblicato in: European Journal of Cardio-Thoracic Surgery, Numero 54/4, 2018, Pagina/e 784-785, ISSN 1010-7940
Editore: Elsevier BV
DOI: 10.1093/ejcts/ezy139

Impact of Acute and Chronic Psychosocial Stress on Vascular Inflammation

Autori: Hinterdobler J, Schunkert H, Kessler T, Sager HB.
Pubblicato in: Antioxid Redox Signal, Numero Volume 35, Numero 18, 2021, ISSN 1523-0864
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ars.2021.0153

Association of In-Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long-Term Mortality in Patients With Acute ST-Segment-Elevation Myocardial Infarction

Autori: Dutsch A, Graesser C, Voll F, Novacek S, Eggerstedt R, Armbruster NL, Laugwitz KL, Cassese S, Schunkert H, Ndrepepa G, Kastrati A, Kessler T, Sager HB.
Pubblicato in: Journal of the American Heart Association, Numero 2022 Sep 6, 2022, ISSN 2047-9980
Editore: Wiley-Blackwell
DOI: 10.1161/jaha.121.024857

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.

Autori: Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB.
Pubblicato in: European Heart Journal, Numero Volume 42, Numero 39, 2021, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehab371