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Developing Multipurpose Nicotiana Crops for Molecular Farming using New Plant Breeding Techniques

Objective

A group of New Plant Breeding Techniques (NPBT) has opened unprecedented opportunities in agriculture. Those NPBTs are at least as efficient and often more precise than previous traditional and GM techniques, while circumventing the introduction of heritable transgenes from distant species in the plant genome. Properly communicated, NPBTs are expected to gain wide acceptance, especially when applied to breeding objectives which are seen as beneficial for the society. A well-perceived objective is Molecular Farming, which refers to the use of plants for the production of valuable biomolecules (e. g. biopharmaceuticals). Cultivated tobacco (Nicotiana tabacum) and its close Australian relative Nicotiana benthamiana, are preferred species in Molecular Farming due to their favourable features: non-food crops, easy tissue regeneration, high productivity, rich secondary metabolism and availability of genetic tools. In sharp contrast, traditional tobacco cultivation is in serious decline in the EU, causing serious social problems in many rural areas. NEWCOTIANA aims to revitalize those areas by breeding efficient Nicotiana biofactories of high-value non-smoking products as alternatives for traditional tobacco crops. NEWCOTIANA will develop the most advanced tobacco NPBTs toolbox, easily transferable to other plants. This will position EU in the avant-garde of breeding innovation. This toolbox will be used to create elite multipurpose Nicotiana varieties improved in product-specific traits (bioproduct quality, stability and yield), next to more general traits as biomass, resilience and biosafety. The “Newcotiana” varieties will be carefully tested in relevant pre-industrial environments for the production of end-value chemicals, namely proteins and metabolites for health and nutriceutical use. Ethical, social and legal aspects will be closely monitored and public and stakeholder engagement will be assured using innovative science communication methodologies.

Call for proposal

H2020-NMBP-2016-2017

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Sub call

H2020-NMBP-BIO-2017

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Net EU contribution
€ 702 581,25
Address
Calle Serrano 117
28006 Madrid
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (20)

ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE
United Kingdom
Net EU contribution
€ 459 862,50
Address
Egham Hill University Of London
TW20 0EX Egham

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Region
South East (England) Surrey, East and West Sussex West Surrey
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE, L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE
Italy
Net EU contribution
€ 465 000,00
Address
Lungotevere Grande Ammiraglio Thaon Di Revel 76
00196 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 0,00
VIB VZW
Belgium
Net EU contribution
€ 359 475,00
Address
Rijvisschestraat 120
9052 Zwijnaarde - Gent

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Research Organisations
Non-EU contribution
€ 0,00
ASOCIACION EMPRESARIAL DE INVESTIGACION CENTRO TECNOLOGICO NACIONAL AGROALIMENTARIO EXTREMADURA
Spain
Net EU contribution
€ 292 107,50
Address
Ctra Villafranco A Balboa Km 1,2
06195 Villafranco Del Guadiana (Badajoz)

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Extremadura Badajoz
Activity type
Research Organisations
Non-EU contribution
€ 0,00
UNIVERSITAET FUER BODENKULTUR WIEN
Austria
Net EU contribution
€ 426 131,25
Address
Gregor Mendel Strasse 33
1180 Wien

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
JOHN INNES CENTRE
United Kingdom
Net EU contribution
€ 349 792,50
Address
Norwich Research Park Colney
NR4 7UH Norwich

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Region
East of England East Anglia Breckland and South Norfolk
Activity type
Research Organisations
Non-EU contribution
€ 0,00
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germany
Net EU contribution
€ 388 271,25
Address
Kaiserstrasse 12
76131 Karlsruhe

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Region
Baden-Württemberg Karlsruhe Karlsruhe, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
LEIBNIZ-INSTITUT FUR PFLANZENBIOCHEMIE
Germany
Net EU contribution
€ 251 250,00
Address
Weinberg 3
06120 Halle

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Region
Sachsen-Anhalt Sachsen-Anhalt Halle (Saale), Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
Net EU contribution
€ 576 125,00
Address
Hofgartenstrasse 8
80539 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BIOFACTION KG
Austria
Net EU contribution
€ 338 131,25
Address
Kundmanngasse 39/12
1030 Wien

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Wien Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 371 321,25
Address
Wellington Square University Offices
OX1 2JD Oxford

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany
Net EU contribution
€ 495 513,75
Address
Hansastrasse 27c
80686 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Philip Morris Products S.A.
Switzerland
Net EU contribution
€ 306 250,00
Address
Quai Jeanrenaud 56
2000 Neuchatel

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Region
Schweiz/Suisse/Svizzera Espace Mittelland Neuchâtel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ST GEORGE'S HOSPITAL MEDICAL SCHOOL
United Kingdom
Net EU contribution
€ 562 822,50
Address
Cranmer Terrace
SW17 0RE London

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Region
London Inner London — West Wandsworth
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
IDOASIS 2002 SL
Spain
Net EU contribution
€ 228 125,00
Address
C/ Tellez, 25 2-1
28007 Madrid

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

NATAC BIOTECH SL
Spain
Net EU contribution
€ 115 750,00
Address
C/ Poligono Industrial Las Canadas S/n
10700 Hervas

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Extremadura Cáceres
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
QUEENSLAND UNIVERSITY OF TECHNOLOGY - QLD QUT
Australia
Net EU contribution
€ 0,00
Address
George Street 2
4001 Brisbane

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 163 750,00
SESDERMA SL
Spain
Net EU contribution
€ 155 737,50
Address
Calle Massamagrell 5 Poligono Industrial Rafelbunyol
46138 Rafelbunyol

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Region
Este Comunitat Valenciana Valencia/València
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

DERMOPARTNERS S.L.
Spain
Net EU contribution
€ 36 250,00
Address
Calle Massamagrell 3 Rafelbunyol
46138 Valencia

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Region
Este Comunitat Valenciana Valencia/València
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
NEUTRAL SUPPLY CHAIN LIMITED
United Kingdom
Net EU contribution
€ 319 062,50
Address
Centrum House 36 Station Road
TW20 9LF Egham Surrey

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South East (England) Surrey, East and West Sussex West Surrey
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00