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GRACIOUS: Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products

Objective

Manufacturing and functionalising materials at the nanoscale leads to a whole array of nanomaterials (NMs) varying in e.g. size, morphology and surface characteristics. Apart from expected benefits, distinctive properties of NMs may also affect (environmental) health risks. Safety assessment requires sufficient information for each NM, but testing every unique NM for their potential adverse effects is virtually impossible. More efficient ways to obtain safety information are needed, which could be achieved by applying grouping and read-across approaches to NMs. On a conceptual level, regulatory accepted approaches for grouping and read-across for NMs already exist, but actual application remains difficult as the required knowledge is not systematically brought together, lacks data curation or is still missing. GRACIOUS will address this urgent need by developing a framework for grouping and read-across based on physicochemical, release, exposure, environmental fate, toxicokinetic and toxicological information. This framework will be delivered as a practical e-tool, fit-for-purpose for various key (regulatory and industrial) stakeholders, who will be engaged from the start of the project. To develop the framework, GRACIOUS will build upon currently available approaches by collating, curating and assimilating existing and new knowledge on intrinsic and extrinsic physicochemical properties in relation to their (environmental) health risk. The resulting framework will support safe innovation by enabling considerations of safety a.o. via grouping and read-across in industrial decision making at various stages of product development. For regulators and policy makers, GRACIOUS will facilitate actual application of grouping and read-across of NMs to enable risk analysis of NMs without extensive testing.

Call for proposal

H2020-NMBP-2016-2017

See other projects for this call

Sub call

H2020-NMBP-2017-two-stage

Coordinator

HERIOT-WATT UNIVERSITY
Net EU contribution
€ 860 792,50
Address
Riccarton
EH14 4AS Edinburgh
United Kingdom

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Region
Scotland Eastern Scotland Edinburgh
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (24)

BASF SE
Germany
Net EU contribution
€ 695 868,75
Address
Carl Bosch Strasse 38
67063 Ludwigshafen Am Rhein

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
GREENDECISION SRL
Italy
Net EU contribution
€ 405 675,00
Address
Via Torino 155/a
30172 Venezia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Est Veneto Venezia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
INSTITUTE OF OCCUPATIONAL MEDICINE
United Kingdom
Net EU contribution
€ 314 975,00
Address
Research Avenue North, Riccarton 45
EH14 4AP Edinburgh

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Scotland Eastern Scotland Edinburgh
Activity type
Research Organisations
Other funding
€ 0,00
EUROPEAN RESEARCH SERVICES GMBH
Germany
Net EU contribution
€ 301 537,50
Address
Huefferstr. 5
48149 Muenster

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Region
Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
YORDAS LIMITED
United Kingdom
Net EU contribution
€ 117 000,00
Address
50-54 Berry Lane
PR3 3JP Longridge Preston

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
North West (England) Lancashire Mid Lancashire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
DET NATIONALE FORSKNINGSCENTER FOR ARBEJDSMILJØ
Denmark
Net EU contribution
€ 411 162,50
Address
Lerso Parkalle 105
2100 Kobenhavn

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Region
Danmark Hovedstaden Byen København
Activity type
Research Organisations
Other funding
€ 0,00
BUNDESINSTITUT FUER RISIKOBEWERTUNG
Germany
Net EU contribution
€ 416 955,00
Address
Max Dohrn Strasse 8-10
10589 Berlin

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Region
Berlin Berlin Berlin
Activity type
Research Organisations
Other funding
€ 0,00
UNITED KINGDOM RESEARCH AND INNOVATION

Participation ended

United Kingdom
Net EU contribution
€ 97 133,75
Address
Polaris House North Star Avenue
SN2 1FL Swindon
Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon
Activity type
Research Organisations
Other funding
€ 0,00
UNIVERSITAT WIEN
Austria
Net EU contribution
€ 309 037,50
Address
Universitatsring 1
1010 Wien

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Region
Ostösterreich Wien Wien
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy
Net EU contribution
€ 217 502,50
Address
Via Morego 30
16163 Genova

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Region
Nord-Ovest Liguria Genova
Activity type
Research Organisations
Other funding
€ 0,00
RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU
Netherlands
Net EU contribution
€ 531 968,75
Address
Antonie Van Leeuwenhoeklaan 9
3721 MA Bilthoven

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Region
West-Nederland Utrecht Utrecht
Activity type
Research Organisations
Other funding
€ 0,00
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
Net EU contribution
€ 217 588,75
Address
Raemistrasse 101
8092 Zuerich

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ACONDICIONAMIENTO TARRASENSE ASSOCIACION
Spain
Net EU contribution
€ 395 787,50
Address
Carrer De La Innovacio 2
08225 Terrassa

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
Nouryon PULP AND PERFORMANCE CHEMICALS AB
Sweden
Net EU contribution
€ 99 975,00
Address
.
445 80 Bohus

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Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
IDEACONSULT LIMITED LIABILITY COMPANY
Bulgaria
Net EU contribution
€ 216 593,75
Address
Angel Kanchev 4
1000 Sofia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Югозападна и Южна централна България Югозападен София (столица)
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
JRC -JOINT RESEARCH CENTRE- EUROPEAN COMMISSION
Belgium
Net EU contribution
€ 323 947,50
Address
Rue De La Loi 200
1049 Brussels

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Research Organisations
Other funding
€ 0,00
UNILEVER U.K. CENTRAL RESOURCES LIMITED

Participation ended

United Kingdom
Net EU contribution
€ 9 451,25
Address
Unilever House, Victoria Embankment 100
EC4Y 0DY London
Region
London Inner London — West Camden and City of London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
THINKWORKS BV
Netherlands
Net EU contribution
€ 249 343,75
Address
Rotterdamseweg 183 C
2629 HD Delft

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Delft en Westland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
ARIZONA BOARD OF REGENTS
United States
Net EU contribution
€ 0,00
Address
660 S Mill Avenue Centerpoint 312
85281 Tempe

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 40 000,00
DUKE UNIVERSITY
United States
Net EU contribution
€ 0,00
Address
Allen Building 207
27708 Durham Nc

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 140 750,00
ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS
Greece
Net EU contribution
€ 148 468,75
Address
Artemidos 6 Kai Epidavrou
151 25 Maroussi

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Region
Αττική Aττική Βόρειος Τομέας Αθηνών
Activity type
Research Organisations
Other funding
€ 0,00
EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT
Switzerland
Net EU contribution
€ 173 787,50
Address
Ueberlandstrasse 129
8600 Dubendorf

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
YORDAS GMBH
Germany
Net EU contribution
€ 132 162,50
Address
Aussere Nurnberger Strasse 62
91301 Forchheim

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Region
Bayern Oberfranken Forchheim
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UK CENTRE FOR ECOLOGY & HYDROLOGY
United Kingdom
Net EU contribution
€ 352 653,75
Address
Maclean Building Benson Lane Crowmarsh Gifford
OX10 8BB Oxford

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Research Organisations
Other funding
€ 0,00