Integration of Nano- and Biotechnology for beta-cell and islet Transplantation

Project Information

iNanoBIT

Grant agreement ID: 760986

DOI 10.3030/760986

Project closed

EC signature date 16 October 2017

Start date 1 October 2017

End date 31 March 2023

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Total cost € 6 999 997,50

EU contribution € 6 999 997,50

Coordinated by

BIOTALENTUM TUDASFEJLESZTO KFT
Hungary

Publications

Peer reviewed articles (16)

Combined Analytical Approaches to Standardize and Characterize Biomaterials Formulations: Application to Chitosan-Gelatin Cross-Linked Hydrogels

Author(s): Sofia Magli, Lorenzo Rossi, Cesare Consentino, Sabrina Bertini, Francesco Nicotra, Laura Russo
Published in: Biomolecules, Issue 11/5, 2021, Page(s) 683, ISSN 2218-273X
Publisher: International Journal of Molecular Sciences
DOI: 10.3390/biom11050683

A decade of experience with genetically tailored pig models for diabetes and metabolic research

Author(s): Silja Zettler, Simone Renner, Elisabeth Kemter, Arne Hinrichs, Nikolai Klymiuk, Mattias Backman, Evamaria Olga Riedel, Christiane Mueller, Elisabeth Streckel, Christina Braun-Reichhart, Ana Sofia Martins, Mayuko Kurome, Barbara Keßler, Valeri Zakhartchenko, Florian Flenkenthaler, Georg Josef Arnold, Thomas Fröhlich, Helmut Blum, Andreas Blutke, Rüdiger Wanke, Eckhard Wolf
Published in: Animal Reproduction, Issue 17/3, 2020, ISSN 1806-9614
Publisher: Colegio Brasileiro de Reproducao Animal
DOI: 10.1590/1984-3143-ar2020-0064

A New Approach for Glyco-Functionalization of Collagen-Based Biomaterials

Author(s): Ines Figuereido, Alice Paiotta, Roberta Dal Magro, Francesca Tinelli, Roberta Corti, Francesca Re, Valeria Cassina, Enrico Caneva, Francesco Nicotra, Laura Russo
Published in: International Journal of Molecular Sciences, Issue 20/7, 2019, Page(s) 1747, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20071747

Integration of nano‐ and biotechnology for beta‐cell and islet transplantation in type‐1 diabetes treatment

Author(s): Andras Dinnyes, Andrea Schnur, Suchitra Muenthaisong, Peter Bartenstein, Charles‐Thibault Burcez, Neal Burton, Clemens Cyran, Pierre Gianello, Elisabeth Kemter, Gabor Nemeth, Francesco Nicotra, Eszter Prepost, Yi Qiu, Laura Russo, Andras Wirth, Eckhard Wolf, Sibylle Ziegler, Julianna Kobolak
Published in: Cell Proliferation, Issue 53/5, 2020, ISSN 0960-7722
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/cpr.12785

3D printed tissue models: From hydrogels to biomedical applications

Author(s): Francesca Cadamuro; Francesco Nicotra; Laura Russo
Published in: Journal of Controlled Release, Issue 3, 2023, Page(s) Pages 726-745, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2023.01.048

Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter

Author(s): Anita Fehér, Andrea Schnúr, Suchitra Muenthaisong, Tamás Bellák, Ferhan Ayaydin, György Várady, Elisabeth Kemter, Eckhard Wolf & András Dinnyés
Published in: Scientific Reports, 2022, Page(s) Article number: 9874, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-12956-1

Replacing Needle Injection by a Novel Waterjet Technology Grants Improved Muscle Cell Delivery in Target Tissues

Author(s): Ruizhi Geng , Jasmin Knoll, Niklas Harland, Bastian Amend, Markus D. Enderle, Walter Linzenbold, Tanja Abruzzese, Claudia Kalbe, Elisabeth Kemter, Eckhard Wolf, Martin Schenk, Arnulf Stenzl, and Wilhelm K. Aicher
Published in: Cell Transplantation, 2022, Page(s) Volume 31: 1–17, ISSN 0963-6897
Publisher: Cognizant Communication Corp.
DOI: 10.1177/09636897221080943

Directed self-assembly of a xenogeneic vascularized endocrine pancreas for type 1 diabetes

Author(s): Antonio Citro, Alessia Neroni, Cataldo Pignatelli, Francesco Campo, Martina Policardi, Matteo Monieri, Silvia Pellegrini, Erica Dugnani, Fabio Manenti, Maria Chiara Maffia, Libera Valla, Elisabeth Kemter, Ilaria Marzinotto, Cristina Olgasi, Alessia Cucci, Antonia Follenzi, Vito Lampasona, Eckhard Wolf, Lorenzo Piemonti
Published in: Nature Communications, 2023, Page(s) Article number: 878, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-36582-1

Click Chemistry Protocol for 3D Bioprintable Elastin−Hyaluronic Acid Hydrogels

Author(s): Cadamuro F., Sampaolesi S., Bertolini G., Roz L., Nicotra F., Russo L
Published in: ChemNanoMat, 2023, ISSN 2199-692X
Publisher: Asian Chemical Editorial Society (ACES)
DOI: 10.1002/cnma.202200508

Porcine models for studying complications and organ crosstalk in diabetes mellitus

Author(s): Simone Renner, Andreas Blutke, Sebastian Clauss, Cornelia A. Deeg, Elisabeth Kemter, Daphne Merkus, Rüdiger Wanke, Eckhard Wolf
Published in: Cell and Tissue Research, Issue 380/2, 2020, Page(s) 341-378, ISSN 0302-766X
Publisher: Springer Verlag
DOI: 10.1007/s00441-019-03158-9

Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic?

Author(s): Elisabeth Kemter, Joachim Denner, Eckhard Wolf
Published in: Current Diabetes Reports, Issue 18/11, 2018, ISSN 1534-4827
Publisher: Current Science Inc.
DOI: 10.1007/s11892-018-1074-5

Recent progress in porcine islet isolation, culture and engraftment strategies for xenotransplantation

Author(s): Elisabeth Kemter, Eckhard Wolf
Published in: Current Opinion in Organ Transplantation, 2018, Page(s) 1, ISSN 1087-2418
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mot.0000000000000579

Glycans in nanomedicine, impact and perspectives

Author(s): Susanna Sampaolesi, Francesco Nicotra, Laura Russo
Published in: Future Medicinal Chemistry, Issue 11/1, 2019, Page(s) 43-60, ISSN 1756-8919
Publisher: Future Science Ltd.
DOI: 10.4155/fmc-2018-0368

3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate

Author(s): Julien Nicolas, Sofia Magli, Linda Rabbachin, Susanna Sampaolesi, Francesco Nicotra, Laura Russo
Published in: Biomacromolecules, Issue 21/6, 2020, Page(s) 1968-1994, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.0c00045

Transgenic pigs expressing near infrared fluorescent protein — A novel tool for noninvasive imaging of islet xenotransplants

Author(s): Kemter, E., A. Citro, L. W-v. Buerck, Y. Qui, A. Böttcher, M. Policardi, S. Pellegrini, L. Valla, M. Alunni-Fabbroni, J. Kobolak, B. Kessler, M. Kurome, V. Zakhartchenko, A. Dinnyes, C.C. Cyran, H. Lickert, L. Piemont, J. Seissler, E. Wolf.
Published in: Xenotranslpantation, 2021, ISSN 1399-3089
Publisher: IXA
DOI: 10.1111/xen.12719

3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans

Author(s): Cadamuro F., Marongiu L, Marino M., Tamini N., Nespoli L., Zucchini N., Terzi A., Altamura D., Gao Z., Giannini C., Bindi G., Smith A., Magni F., Bertini S., Granucci F., Nicotra F., Russo L.
Published in: Carbohydrate Polymers, 2023, ISSN 0144-8617
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2022.120395