Integration of Nano- and Biotechnology for beta-cell and islet Transplantation

Informations projet

iNanoBIT

N° de convention de subvention: 760986

DOI 10.3030/760986

Projet clôturé

Date de signature de la CE 16 Octobre 2017

Date de début 1 Octobre 2017

Date de fin 31 Mars 2023

Financé au titre de

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Coût total € 6 999 997,50

Contribution de l’UE € 6 999 997,50

Coordonné par

BIOTALENTUM TUDASFEJLESZTO KFT
Hungary

Publications

Peer reviewed articles (16)

Combined Analytical Approaches to Standardize and Characterize Biomaterials Formulations: Application to Chitosan-Gelatin Cross-Linked Hydrogels

Auteurs: Sofia Magli, Lorenzo Rossi, Cesare Consentino, Sabrina Bertini, Francesco Nicotra, Laura Russo
Publié dans: Biomolecules, Numéro 11/5, 2021, Page(s) 683, ISSN 2218-273X
Éditeur: International Journal of Molecular Sciences
DOI: 10.3390/biom11050683

A decade of experience with genetically tailored pig models for diabetes and metabolic research

Auteurs: Silja Zettler, Simone Renner, Elisabeth Kemter, Arne Hinrichs, Nikolai Klymiuk, Mattias Backman, Evamaria Olga Riedel, Christiane Mueller, Elisabeth Streckel, Christina Braun-Reichhart, Ana Sofia Martins, Mayuko Kurome, Barbara Keßler, Valeri Zakhartchenko, Florian Flenkenthaler, Georg Josef Arnold, Thomas Fröhlich, Helmut Blum, Andreas Blutke, Rüdiger Wanke, Eckhard Wolf
Publié dans: Animal Reproduction, Numéro 17/3, 2020, ISSN 1806-9614
Éditeur: Colegio Brasileiro de Reproducao Animal
DOI: 10.1590/1984-3143-ar2020-0064

A New Approach for Glyco-Functionalization of Collagen-Based Biomaterials

Auteurs: Ines Figuereido, Alice Paiotta, Roberta Dal Magro, Francesca Tinelli, Roberta Corti, Francesca Re, Valeria Cassina, Enrico Caneva, Francesco Nicotra, Laura Russo
Publié dans: International Journal of Molecular Sciences, Numéro 20/7, 2019, Page(s) 1747, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20071747

Integration of nano‐ and biotechnology for beta‐cell and islet transplantation in type‐1 diabetes treatment

Auteurs: Andras Dinnyes, Andrea Schnur, Suchitra Muenthaisong, Peter Bartenstein, Charles‐Thibault Burcez, Neal Burton, Clemens Cyran, Pierre Gianello, Elisabeth Kemter, Gabor Nemeth, Francesco Nicotra, Eszter Prepost, Yi Qiu, Laura Russo, Andras Wirth, Eckhard Wolf, Sibylle Ziegler, Julianna Kobolak
Publié dans: Cell Proliferation, Numéro 53/5, 2020, ISSN 0960-7722
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cpr.12785

3D printed tissue models: From hydrogels to biomedical applications

Auteurs: Francesca Cadamuro; Francesco Nicotra; Laura Russo
Publié dans: Journal of Controlled Release, Numéro 3, 2023, Page(s) Pages 726-745, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2023.01.048

Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter

Auteurs: Anita Fehér, Andrea Schnúr, Suchitra Muenthaisong, Tamás Bellák, Ferhan Ayaydin, György Várady, Elisabeth Kemter, Eckhard Wolf & András Dinnyés
Publié dans: Scientific Reports, 2022, Page(s) Article number: 9874, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-12956-1

Replacing Needle Injection by a Novel Waterjet Technology Grants Improved Muscle Cell Delivery in Target Tissues

Auteurs: Ruizhi Geng , Jasmin Knoll, Niklas Harland, Bastian Amend, Markus D. Enderle, Walter Linzenbold, Tanja Abruzzese, Claudia Kalbe, Elisabeth Kemter, Eckhard Wolf, Martin Schenk, Arnulf Stenzl, and Wilhelm K. Aicher
Publié dans: Cell Transplantation, 2022, Page(s) Volume 31: 1–17, ISSN 0963-6897
Éditeur: Cognizant Communication Corp.
DOI: 10.1177/09636897221080943

Directed self-assembly of a xenogeneic vascularized endocrine pancreas for type 1 diabetes

Auteurs: Antonio Citro, Alessia Neroni, Cataldo Pignatelli, Francesco Campo, Martina Policardi, Matteo Monieri, Silvia Pellegrini, Erica Dugnani, Fabio Manenti, Maria Chiara Maffia, Libera Valla, Elisabeth Kemter, Ilaria Marzinotto, Cristina Olgasi, Alessia Cucci, Antonia Follenzi, Vito Lampasona, Eckhard Wolf, Lorenzo Piemonti
Publié dans: Nature Communications, 2023, Page(s) Article number: 878, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-36582-1

Click Chemistry Protocol for 3D Bioprintable Elastin−Hyaluronic Acid Hydrogels

Auteurs: Cadamuro F., Sampaolesi S., Bertolini G., Roz L., Nicotra F., Russo L
Publié dans: ChemNanoMat, 2023, ISSN 2199-692X
Éditeur: Asian Chemical Editorial Society (ACES)
DOI: 10.1002/cnma.202200508

Porcine models for studying complications and organ crosstalk in diabetes mellitus

Auteurs: Simone Renner, Andreas Blutke, Sebastian Clauss, Cornelia A. Deeg, Elisabeth Kemter, Daphne Merkus, Rüdiger Wanke, Eckhard Wolf
Publié dans: Cell and Tissue Research, Numéro 380/2, 2020, Page(s) 341-378, ISSN 0302-766X
Éditeur: Springer Verlag
DOI: 10.1007/s00441-019-03158-9

Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic?

Auteurs: Elisabeth Kemter, Joachim Denner, Eckhard Wolf
Publié dans: Current Diabetes Reports, Numéro 18/11, 2018, ISSN 1534-4827
Éditeur: Current Science Inc.
DOI: 10.1007/s11892-018-1074-5

Recent progress in porcine islet isolation, culture and engraftment strategies for xenotransplantation

Auteurs: Elisabeth Kemter, Eckhard Wolf
Publié dans: Current Opinion in Organ Transplantation, 2018, Page(s) 1, ISSN 1087-2418
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mot.0000000000000579

Glycans in nanomedicine, impact and perspectives

Auteurs: Susanna Sampaolesi, Francesco Nicotra, Laura Russo
Publié dans: Future Medicinal Chemistry, Numéro 11/1, 2019, Page(s) 43-60, ISSN 1756-8919
Éditeur: Future Science Ltd.
DOI: 10.4155/fmc-2018-0368

3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate

Auteurs: Julien Nicolas, Sofia Magli, Linda Rabbachin, Susanna Sampaolesi, Francesco Nicotra, Laura Russo
Publié dans: Biomacromolecules, Numéro 21/6, 2020, Page(s) 1968-1994, ISSN 1525-7797
Éditeur: American Chemical Society
DOI: 10.1021/acs.biomac.0c00045

Transgenic pigs expressing near infrared fluorescent protein — A novel tool for noninvasive imaging of islet xenotransplants

Auteurs: Kemter, E., A. Citro, L. W-v. Buerck, Y. Qui, A. Böttcher, M. Policardi, S. Pellegrini, L. Valla, M. Alunni-Fabbroni, J. Kobolak, B. Kessler, M. Kurome, V. Zakhartchenko, A. Dinnyes, C.C. Cyran, H. Lickert, L. Piemont, J. Seissler, E. Wolf.
Publié dans: Xenotranslpantation, 2021, ISSN 1399-3089
Éditeur: IXA
DOI: 10.1111/xen.12719

3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans

Auteurs: Cadamuro F., Marongiu L, Marino M., Tamini N., Nespoli L., Zucchini N., Terzi A., Altamura D., Gao Z., Giannini C., Bindi G., Smith A., Magni F., Bertini S., Granucci F., Nicotra F., Russo L.
Publié dans: Carbohydrate Polymers, 2023, ISSN 0144-8617
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2022.120395