Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Project Information

TOBeATPAIN

Grant agreement ID: 764860

DOI

10.3030/764860

Project closed

EC signature date 5 July 2018

Start date 1 August 2018

End date 31 July 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 2 870 359,20

EU contribution

€ 2 870 359,20

Coordinated by

KING'S COLLEGE LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Websites, patent fillings, videos etc. (1)

TOBeATPAIN Website

Documents, reports (3)

Dissemination & Communication Report II

Dissemination Communication Report

Dissemination & Communication Report I

Dissemination & Communication Report

Scientific papers in peer-reviewed journals

Scientific papers in peerreviewed journals

Other (1)

TOBeATPAIN Conference

Publications

Peer reviewed articles (16)

Pain in the neurodegenerating brain: insights into pharmacotherapy for Alzheimer disease and Parkinson disease

Author(s): Lawn, Timothy; Aman, Yahyah; Rukavina, Katarina; Sideris-Lampretsas, George; Howard, Matthew; Ballard, Clive; Ray Chaudhuri, Kallol; Malcangio, Marzia
Published in: PAIN, Issue 162, 2021, Page(s) 999-1006, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000002111

Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls

Author(s): Isabel Ellerbrock, Angelica Sandström, Jeanette Tour, Silvia Fanton, Diana Kadetoff, Martin Schalling, Karin B. Jensen, Rouslan Sitnikov, Eva Kosek
Published in: Molecular Brain, Issue 14/1, 2021, ISSN 1756-6606
Publisher: BioMed Central
DOI: 10.1186/s13041-021-00789-4

Interactions of the neuropeptide galanin with cortical spreading depolarization and cortical neuronal excitability

Author(s): Gimeno-Ferrer, F,; Eitner, A.; Bauer, R.; Lehmenkuhler, A.; Schaible, H-G.; Richter, F.
Published in: Journal of Headache and Pain, Issue 1, 2021, Page(s) Vol 22 Issue Supp 1 pg 41, ISSN 1129-2377
Publisher: Springer Nature
DOI: 10.5281/zenodo.6242314

From spreading depolarization to epilepsy with neuroinflammation: Therole of CGRP in cortex

Author(s): Fatima Gimeno-Ferrer, Annett Eitner, Reinhard Bauer, Alfred Lehmenkühler, MarieLuise Edenhofer, Michaela Kress, Hans-Georg Schaible, Frank Richter
Published in: Experimental Neurology, Issue Vol 356,, 2022, ISSN 0014-4886
Publisher: Academic Press
DOI: 10.1016/j.expneurol.2022.114152

Pain-Resolving Microglial

Author(s): Sideris-Lampretsas, George, Malcangio, Marzia
Published in: SCIENCE, Issue Vol 376, Issues 6588, 2022, Page(s) 33-34, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abo5592

Role of the immune system in neuropathic pain

Author(s): Marzia Malcangio
Published in: Scandinavian Journal of Pain, Issue 20/1, 2019, Page(s) 33-37, ISSN 1877-8860
Publisher: Elsevier BV
DOI: 10.1515/sjpain-2019-0138

The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects

Author(s): Silvia Fanton, Angelica Sandström, Jeanette Tour, Diana Kadetoff, Martin Schalling, Karin B. Jensen, Rouslan Sitnikov, Isabel Ellerbrock, Eva Kosek
Published in: Pain, Issue Publish Ahead of Print, 2021, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000002309

Pain in Parkinson's disease: new concepts in pathogenesis and treatment

Author(s): Katarina Rukavina, Valentina Leta, Carolina Sportelli, Yazead Buhidma, Susan Duty, Marzia Malcangio, Kallol Ray Chaudhuri
Published in: Current Opinion in Neurology, Issue 32, 2019, Page(s) 579-588, ISSN 0951-7383
Publisher: Lippincott Williams & Wilkins
DOI: 10.1097/wco.0000000000000711

Microglial heterogeneity in chronic pain

Author(s): George Sideris-Lampretsas, Marzia Malcangio
Published in: Brain, Behavior, and Immunity, 2021, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2021.06.005

Translational value of preclinical models for rheumatoid arthritis pain

Author(s): Marzia Malcangio
Published in: Pain, Issue 161/7, 2020, Page(s) 1399-1400, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000001851

From the low-density lipoprotein receptor–related protein 1 to neuropathic pain: a potentially novel target

Author(s): García-Fernández, Patricia; Üçeyler, Nurcan; Sommer, Claudia
Published in: PAIN Vol 6 Issue 1, Issue 1, 2021, Page(s) 898, ISSN 2471-2531
Publisher: IASP
DOI: 10.1097/PR9.0000000000000898

Animal models of Parkinson's disease: a guide to selecting the optimal model for your research

Author(s): Lama, Joana; Buhidma, Yazead; Fletcher, Edward J.R.; Duty, Susan
Published in: Neuronal Signaling, Issue 2, 2021, Page(s) Vol 5 Issue 4, ISSN 2059-6553
Publisher: Portland Press
DOI: 10.1042/NS20210026

Multiple spatial scale mapping of time-resolved brain network reconfiguration during evoked pain in patients with rheumatoid arthritis

Author(s): Silvia Fanton, Reem Altawil, Isabel Ellerbrock, Jon Lampa, Eva Kosek,Peter Fransson, William H. Thompson
Published in: Frontiers in Neuroscience, Issue 1662453X, 2022, ISSN 1662-453X
Publisher: Frontiers in Neuroscience
DOI: 10.3389/fnins.2022.942136

Potential of animal models for advancing the understanding and treatment of pain in Parkinson’s disease

Author(s): Yazead Buhidma, Katarina Rukavina, Kallol Ray Chaudhuri, Susan Duty
Published in: npj Parkinson's Disease, Issue 6/1, 2020, ISSN 2373-8057
Publisher: https://www.nature.com/npjparkd/
DOI: 10.1038/s41531-019-0104-6

Passive transfer of fibromyalgia symptoms from patients to mice

Author(s): Andreas Goebel; Emerson Krock; Clive Gentry; Mathilde R. Israel; Alexandra Jurczak; Carlos Morado Urbina; Katalin Sandor; Nisha Vastani; Margot Maurer; Ulku Cuhadar; Serena Sensi; Yuki Nomura; Joana Menezes; Azar Baharpoor; Louisa Brieskorn; Angelica Sandström; Jeanette Tour; Diana Kadetoff; Lisbet Haglund; Eva Kosek; Eva Kosek; Stuart Bevan; Camilla I. Svensson; David Andersson
Published in: JOURNAL OF CLINICAL INVESTIGATION, Issue 4, 2021, ISSN 1558-8238
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci144201

Fractalkine/CX3CR1 Pathway in Neuropathic Pain: An Update

Author(s): Rita Silva, Marzia Malcangio
Published in: Frontiers in Pain Research, Issue Volume 2 - 2021, 2021, ISSN 2673-561X
Publisher: Frontiers
DOI: 10.3389/fpain.2021.684684