Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Project Information

TOBeATPAIN

Grant agreement ID: 764860

DOI 10.3030/764860

Project closed

EC signature date 5 July 2018

Start date 1 August 2018

End date 31 July 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 2 870 359,20

EU contribution € 2 870 359,20

Coordinated by

KING'S COLLEGE LONDON
United Kingdom

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Websites, patent fillings, videos etc. (1)

TOBeATPAIN Website

Documents, reports (3)

Dissemination & Communication Report II

Dissemination Communication Report

Dissemination & Communication Report I

Dissemination & Communication Report

Scientific papers in peer-reviewed journals

Scientific papers in peerreviewed journals

Other (1)

TOBeATPAIN Conference

Publications

Peer reviewed articles (16)

Pain in the neurodegenerating brain: insights into pharmacotherapy for Alzheimer disease and Parkinson disease

Author(s): Lawn, Timothy; Aman, Yahyah; Rukavina, Katarina; Sideris-Lampretsas, George; Howard, Matthew; Ballard, Clive; Ray Chaudhuri, Kallol; Malcangio, Marzia
Published in: PAIN, Issue 162, 2021, Page(s) 999-1006, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000002111

Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls

Author(s): Isabel Ellerbrock, Angelica Sandström, Jeanette Tour, Silvia Fanton, Diana Kadetoff, Martin Schalling, Karin B. Jensen, Rouslan Sitnikov, Eva Kosek
Published in: Molecular Brain, Issue 14/1, 2021, ISSN 1756-6606
Publisher: BioMed Central
DOI: 10.1186/s13041-021-00789-4

Interactions of the neuropeptide galanin with cortical spreading depolarization and cortical neuronal excitability

Author(s): Gimeno-Ferrer, F,; Eitner, A.; Bauer, R.; Lehmenkuhler, A.; Schaible, H-G.; Richter, F.
Published in: Journal of Headache and Pain, Issue 1, 2021, Page(s) Vol 22 Issue Supp 1 pg 41, ISSN 1129-2377
Publisher: Springer Nature
DOI: 10.5281/zenodo.6242314

From spreading depolarization to epilepsy with neuroinflammation: Therole of CGRP in cortex

Author(s): Fatima Gimeno-Ferrer, Annett Eitner, Reinhard Bauer, Alfred Lehmenkühler, MarieLuise Edenhofer, Michaela Kress, Hans-Georg Schaible, Frank Richter
Published in: Experimental Neurology, Issue Vol 356,, 2022, ISSN 0014-4886
Publisher: Academic Press
DOI: 10.1016/j.expneurol.2022.114152

Pain-Resolving Microglial

Author(s): Sideris-Lampretsas, George, Malcangio, Marzia
Published in: SCIENCE, Issue Vol 376, Issues 6588, 2022, Page(s) 33-34, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abo5592

Role of the immune system in neuropathic pain

Author(s): Marzia Malcangio
Published in: Scandinavian Journal of Pain, Issue 20/1, 2019, Page(s) 33-37, ISSN 1877-8860
Publisher: Elsevier BV
DOI: 10.1515/sjpain-2019-0138

The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects

Author(s): Silvia Fanton, Angelica Sandström, Jeanette Tour, Diana Kadetoff, Martin Schalling, Karin B. Jensen, Rouslan Sitnikov, Isabel Ellerbrock, Eva Kosek
Published in: Pain, Issue Publish Ahead of Print, 2021, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000002309

Pain in Parkinson's disease: new concepts in pathogenesis and treatment

Author(s): Katarina Rukavina, Valentina Leta, Carolina Sportelli, Yazead Buhidma, Susan Duty, Marzia Malcangio, Kallol Ray Chaudhuri
Published in: Current Opinion in Neurology, Issue 32, 2019, Page(s) 579-588, ISSN 0951-7383
Publisher: Lippincott Williams & Wilkins
DOI: 10.1097/wco.0000000000000711

Microglial heterogeneity in chronic pain

Author(s): George Sideris-Lampretsas, Marzia Malcangio
Published in: Brain, Behavior, and Immunity, 2021, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbi.2021.06.005

Translational value of preclinical models for rheumatoid arthritis pain

Author(s): Marzia Malcangio
Published in: Pain, Issue 161/7, 2020, Page(s) 1399-1400, ISSN 0304-3959
Publisher: Elsevier BV
DOI: 10.1097/j.pain.0000000000001851

From the low-density lipoprotein receptor–related protein 1 to neuropathic pain: a potentially novel target

Author(s): García-Fernández, Patricia; Üçeyler, Nurcan; Sommer, Claudia
Published in: PAIN Vol 6 Issue 1, Issue 1, 2021, Page(s) 898, ISSN 2471-2531
Publisher: IASP
DOI: 10.1097/PR9.0000000000000898

Animal models of Parkinson's disease: a guide to selecting the optimal model for your research

Author(s): Lama, Joana; Buhidma, Yazead; Fletcher, Edward J.R.; Duty, Susan
Published in: Neuronal Signaling, Issue 2, 2021, Page(s) Vol 5 Issue 4, ISSN 2059-6553
Publisher: Portland Press
DOI: 10.1042/NS20210026

Multiple spatial scale mapping of time-resolved brain network reconfiguration during evoked pain in patients with rheumatoid arthritis

Author(s): Silvia Fanton, Reem Altawil, Isabel Ellerbrock, Jon Lampa, Eva Kosek,Peter Fransson, William H. Thompson
Published in: Frontiers in Neuroscience, Issue 1662453X, 2022, ISSN 1662-453X
Publisher: Frontiers in Neuroscience
DOI: 10.3389/fnins.2022.942136

Potential of animal models for advancing the understanding and treatment of pain in Parkinson’s disease

Author(s): Yazead Buhidma, Katarina Rukavina, Kallol Ray Chaudhuri, Susan Duty
Published in: npj Parkinson's Disease, Issue 6/1, 2020, ISSN 2373-8057
Publisher: https://www.nature.com/npjparkd/
DOI: 10.1038/s41531-019-0104-6

Passive transfer of fibromyalgia symptoms from patients to mice

Author(s): Andreas Goebel; Emerson Krock; Clive Gentry; Mathilde R. Israel; Alexandra Jurczak; Carlos Morado Urbina; Katalin Sandor; Nisha Vastani; Margot Maurer; Ulku Cuhadar; Serena Sensi; Yuki Nomura; Joana Menezes; Azar Baharpoor; Louisa Brieskorn; Angelica Sandström; Jeanette Tour; Diana Kadetoff; Lisbet Haglund; Eva Kosek; Eva Kosek; Stuart Bevan; Camilla I. Svensson; David Andersson
Published in: JOURNAL OF CLINICAL INVESTIGATION, Issue 4, 2021, ISSN 1558-8238
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci144201

Fractalkine/CX3CR1 Pathway in Neuropathic Pain: An Update

Author(s): Rita Silva, Marzia Malcangio
Published in: Frontiers in Pain Research, Issue Volume 2 - 2021, 2021, ISSN 2673-561X
Publisher: Frontiers
DOI: 10.3389/fpain.2021.684684