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Light-driven sustainable biocatalysis training network

Deliverables

Blogs, podcasts and newsletter

A collection of written public material used for public engagement activities.

Methodology video

As part of the public engagement strategy, a methodology video will be produced by the ESRs.

PhotoBioCat Conference website

Design and maintenance of the PhotoBioCat conference website

Website

Design, maintenance and content management of PhotoBioCat website.

Advertise ESR positions

Advertisement of the open ESR positions in the internet.

Conference organization

The PhotoBioCat project will organize a conference led by the ESRs

Research topic special issue

The project will organize a journal special issue to publish selected articles in the field of Photo Biocatalysis.

Training events

Report on the Training events conducted by the PhotoBioCat project

Network-wide training report

A detailed information on the training progress of each ESRs based on the harmonization plan of the project This report also includes the results of the participation to the MARGA Business Simulation

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Publications

Photo-biocatalytic Cascades: Combining Chemical and Enzymatic Transformations Fueled by Light

Author(s): Fatma Feyza Özgen, Michael E. Runda, and Sandy Schmidt
Published in: ChemBioChem, 2020, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000587

Flavoenzyme-mediated regioselective aromatic hydroxylation with coenzyme biomimetics

Author(s): Guarneri, A. Westphal, A. H. Leertouwer, J. Lunsonga, J. Franssen, M. C. R. Opperman, D. J. Hollmann, F. van Berkel, W. J. H. Paul, C. E.
Published in: ChemCatChem, 2020, Page(s) 1368–1375, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201902044

The Right Light: De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry

Author(s): H. E. Bonfield, K. Mercer, A. Diaz-Rodriguez, G. C. Cook, B. S. J. McKay, P. Slade, G. M. Taylor, W. Xiang Ooi, J. D. Williams, J. P. M. Roberts, J. A. Murphy, L. Schmermund, W. Kroutil, T. Mielke, J. Cartwright, G. Grogan, L. J. Edwards
Published in: ChemPhotoChem, 2020, Page(s) 45-51, ISSN 2367-0932
Publisher: Wiley-VCH
DOI: 10.1002/cptc.201900203

Artificial Light-Harvesting Complexes Enable Rieske Oxygenase Catalyzed Hydroxylations in Non-Photosynthetic cells.

Author(s): Feyza Özgen, F.; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy
Published in: Angewandte Chemie (International Ed. in English), 3, 2020, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201914519

Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations

Author(s): Markus Hobisch, Dirk Holtmann, Patricia Gomez de Santos, Miguel Alcalde, Frank Hollmann, Selin Kara
Published in: Biotechnology Advances, 2021, ISSN 0734-9750
Publisher: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107615

Internal Illumination to Overcome the Cell Density Limitation in the Scale-up of Whole-cell Photobiocatalysis

Author(s): Markus Hobisch, Jelena Spasic, Lenny Malihan-Yap, Giovanni Davide Barone, Kathrin Castiglione, Paula Tamagnini, Selin Kara, Robert Kourist
Published in: ChemSusChem, 2021, ISSN 1864-5631
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202100832

Shortening Synthetic Routes to Small Molecule Active Pharmaceutical Ingredients Employing Biocatalytic Methods

Author(s): S. Simić, E. Zukić, L. Schmermund, K. Faber, C. K. Winkler, W. Kroutil
Published in: Chem. Rev., 122, 2022, Page(s) 1052–1126, ISSN 1520-6890
Publisher: American Chemical Society (United States)
DOI: 10.1021/acs.chemrev.1c00574

Solvent-Free Photobiocatalytic Hydroxylation of Cyclohexane

Author(s): Markus Hobisch, Morten Martinus Cornelis Harald van Schie, Jinhyun Kim, Kasper Røjkjær Andersen, Miguel Alcalde, Robert Kourist, Chan Beum Park, Frank Hollmann, Selin Kara
Published in: ChemCatChem, 2020, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202000512

Synthesis of Enantiopure Sulfoxides by Concurrent Photocatalytic Oxidation and Biocatalytic Reduction

Author(s): S. Bierbaumer, L. Schmermund, A. List, C. K. Winkler, S. M. Glueck, W. Kroutil
Published in: Angewandte Chemie International Edition, 2022, Page(s) e202117103, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202117103

Alternative coenzymes for biocatalysis

Author(s): Alice Guarneri, Willem JH van Berkel, Caroline E Paul
Published in: Current Opinion in Biotechnology, 60, 2019, Page(s) 63-71, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2019.01.001

Enzymatic Ring‐Opening Polymerization of Lactones: Traditional Approaches and Alternative Strategies

Author(s): Jennifer Engel, Alex Cordellier, Lei Huang, Selin Kara
Published in: ChemCatChem, 2019, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201900976

Photo-Biocatalysis: Biotransformations in the Presence of Light

Author(s): Luca Schmermund, Valentina Jurkaš, F. Feyza Özgen, Giovanni D. Barone, Hanna C. Büchsenschütz, Christoph K. Winkler, Sandy Schmidt, Robert Kourist, Wolfgang Kroutil
Published in: ACS Catalysis, 9/5, 2019, Page(s) 4115-4144, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.9b00656

Photobiocatalytic Oxyfunctionalization with High Reaction Rate using a Baeyer–Villiger Monooxygenase from Burkholderia xenovorans in Metabolically Engineered Cyanobacteria

Author(s): Elif Erdem, Lenny Malihan-Yap, Leen Assil-Companioni, Hanna Grimm, Giovanni Davide Barone, Carole Serveau-Avesque, Agnes Amouric, Katia Duquesne, Véronique de Berardinis, Yagut Allahverdiyeva, Véronique Alphand and Robert Kourist
Published in: ACS Catalysis, 12, 2022, Page(s) 66–72, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.1c04555

Synthesis of Enantiopure Sulfoxides by Concurrent Photocatalytic Oxidation and Biocatalytic Reduction

Author(s): Sarah Bierbaumer, Luca Schermund, Alexander List, Christoph Winkler, Silvia M. Glueck, Wolfgang Kroutil
Published in: Angewandte Chemie, International Edition, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202117103

Combining Photo-Organo Redox- and Enzyme Catalysis Facilitates Asymmetric C-H Bond Functionalization

Author(s): Zhang, Wuyuan; Fueyo, Elena Fernandez; Hollmann, Frank; Martin, Laura Leemans; Pesic, Milja; Wardenga, Rainer; Höhne, Matthias; Schmidt, Sandy
Published in: European Journal of Organic Chemistry, 3, 2019, ISSN 1434-193X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.201801692

Artifizielle Lichtsammelkomplexe ermöglichen Rieske‐Oxygenase‐ katalysierte Hydroxylierungen in nicht‐photosynthetischen Zellen

Author(s): Feyza Özgen, F.; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy
Published in: Angewandte Chemie, 3, 2020, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.201914519

Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor

Author(s): C. K. Winkler, S. Simić, V. Jurkaš, S. Bierbaumer, L. Schmermund, S. Poschenrieder, S. A. Berger, E. Kulterer, R. Kourist, W. Kroutil
Published in: ChemPhotoChem, 2021, ISSN 2367-0932
Publisher: Wiely-VCH
DOI: 10.1002/cptc.202100109

Expression and activity of heterologous hydroxyisocaproate dehydrogenases in Synechocystis sp. PCC 6803 ΔhoxYH

Author(s): V. Jurkaš, C. K. Winkler, S. Poschenrieder, P. Oliveira, C. C. Pacheco, E. A. Ferreira, F. Weissensteiner, P. De Santis, S. Kara, R. Kourist, P Tamagnini*, W. Kroutil
Published in: Eng. Microbiol., 1, 2022, Page(s) 100008, ISSN 2667-3703
Publisher: Elsevier B.V.
DOI: 10.1016/j.engmic.2021.100008

Extending the Library of Light‐Dependent Protochlorophyllide Oxidoreductases and their Solvent Tolerance, Stability in Light and Cofactor Flexibility

Author(s): L. Schmermund, S. Bierbaumer, V. K. Schein, C. K. Winkler, S. Kara, W. Kroutil
Published in: ChemCatchem, 12, 2020, Page(s) 4044-4051, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202000561

Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways

Author(s): Luca Schmermund; Susanne Reischauer; Sarah Bierbaumer; Christoph K. Winkler; Alba Diaz-Rodriguez; Lee Edwards; Selin Kara; Tamara Mielke; Jared Cartwright; Gideon Grogan; Bartholomäus Pieber; Wolfgang Kroutil
Published in: Angweandte Chemie, International Edition, 133, 2021, Page(s) 7041-7045, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202100164

Divorce in the two-component BVMO family: the single oxygenase for enantioselective chemo-enzymatic Baeyer–Villiger oxidations

Author(s): R. Röllig, C. E. Paul, M. Claeys-Bruno, K Duquesne, S. Kara, V. Alphand
Published in: Organic and Biomolecular Chemistry, 2021, Page(s) 3441-3450, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1ob00015b

Flavoprotein monooxygenases and halogenases

Author(s): Paul, Caroline E. Guarneri, Alice van Berkel, Willem J.H.
Published in: Flavin‐Based Catalysis: Principles and Applications, 2021, Page(s) 169-199
Publisher: Wiley
DOI: 10.1002/9783527830138.ch7