Light-driven sustainable biocatalysis training network

Informations projet

PhotoBioCat

N° de convention de subvention: 764920

DOI 10.3030/764920

Projet clôturé

Date de signature de la CE 2 Août 2017

Date de début 1 Janvier 2018

Date de fin 31 Decembre 2021

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total € 3 029 067,08

Contribution de l’UE € 3 029 067,08

Coordonné par

TECHNISCHE UNIVERSITAET GRAZ
Austria

Livrables

Websites, patent fillings, videos etc. (4)

Blogs, podcasts and newsletter

A collection of written public material used for public engagement activities.

Methodology video

As part of the public engagement strategy, a methodology video will be produced by the ESRs.

PhotoBioCat Conference website

Design and maintenance of the PhotoBioCat conference website

Website

Design, maintenance and content management of PhotoBioCat website.

Other (3)

Advertise ESR positions

Advertisement of the open ESR positions in the internet.

Conference organization

The PhotoBioCat project will organize a conference led by the ESRs

Research topic special issue

The project will organize a journal special issue to publish selected articles in the field of Photo Biocatalysis.

Documents, reports (2)

Training events

Report on the Training events conducted by the PhotoBioCat project

Network-wide training report

A detailed information on the training progress of each ESRs based on the harmonization plan of the project This report also includes the results of the participation to the MARGA Business Simulation

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (22)

Photo-biocatalytic Cascades: Combining Chemical and Enzymatic Transformations Fueled by Light

Auteurs: Fatma Feyza Özgen, Michael E. Runda, and Sandy Schmidt
Publié dans: ChemBioChem, 2020, ISSN 1439-4227
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202000587

Flavoenzyme-mediated regioselective aromatic hydroxylation with coenzyme biomimetics

Auteurs: Guarneri, A. Westphal, A. H. Leertouwer, J. Lunsonga, J. Franssen, M. C. R. Opperman, D. J. Hollmann, F. van Berkel, W. J. H. Paul, C. E.
Publié dans: ChemCatChem, 2020, Page(s) 1368–1375, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201902044

The Right Light: De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry

Auteurs: H. E. Bonfield, K. Mercer, A. Diaz-Rodriguez, G. C. Cook, B. S. J. McKay, P. Slade, G. M. Taylor, W. Xiang Ooi, J. D. Williams, J. P. M. Roberts, J. A. Murphy, L. Schmermund, W. Kroutil, T. Mielke, J. Cartwright, G. Grogan, L. J. Edwards
Publié dans: ChemPhotoChem, 2020, Page(s) 45-51, ISSN 2367-0932
Éditeur: Wiley-VCH
DOI: 10.1002/cptc.201900203

The Synthesis of Chiral γ-Lactones by Merging Decatungstate Photocatalysis with Biocatalysis

Auteurs: Fatma Feyza Özgen, Alexandra Jorea, Luca Capaldo, Robert Kourist, Davide Ravelli, Sandy Schmidt
Publié dans: ChemCatChem, 2022, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202200855

Artificial Light-Harvesting Complexes Enable Rieske Oxygenase Catalyzed Hydroxylations in Non-Photosynthetic cells.

Auteurs: Feyza Özgen, F.; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy
Publié dans: Angewandte Chemie (International Ed. in English), Numéro 3, 2020, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201914519

Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations

Auteurs: Markus Hobisch, Dirk Holtmann, Patricia Gomez de Santos, Miguel Alcalde, Frank Hollmann, Selin Kara
Publié dans: Biotechnology Advances, 2021, ISSN 0734-9750
Éditeur: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107615

Internal Illumination to Overcome the Cell Density Limitation in the Scale-up of Whole-cell Photobiocatalysis

Auteurs: Markus Hobisch, Jelena Spasic, Lenny Malihan-Yap, Giovanni Davide Barone, Kathrin Castiglione, Paula Tamagnini, Selin Kara, Robert Kourist
Publié dans: ChemSusChem, 2021, ISSN 1864-5631
Éditeur: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cssc.202100832

Shortening Synthetic Routes to Small Molecule Active Pharmaceutical Ingredients Employing Biocatalytic Methods

Auteurs: S. Simić, E. Zukić, L. Schmermund, K. Faber, C. K. Winkler, W. Kroutil
Publié dans: Chem. Rev., Numéro 122, 2022, Page(s) 1052–1126, ISSN 1520-6890
Éditeur: American Chemical Society (United States)
DOI: 10.1021/acs.chemrev.1c00574

Solvent-Free Photobiocatalytic Hydroxylation of Cyclohexane

Auteurs: Markus Hobisch, Morten Martinus Cornelis Harald van Schie, Jinhyun Kim, Kasper Røjkjær Andersen, Miguel Alcalde, Robert Kourist, Chan Beum Park, Frank Hollmann, Selin Kara
Publié dans: ChemCatChem, 2020, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202000512

Synthesis of Enantiopure Sulfoxides by Concurrent Photocatalytic Oxidation and Biocatalytic Reduction

Auteurs: S. Bierbaumer, L. Schmermund, A. List, C. K. Winkler, S. M. Glueck, W. Kroutil
Publié dans: Angewandte Chemie International Edition, 2022, Page(s) e202117103, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202117103

Enzymatic Oxy- and Amino-Functionalization in Biocatalytic Cascade Synthesis: Recent Advances and Future Perspectives

Auteurs: Eleonora Grandi, Fatma Feyza Özgen, Sandy Schmidt, Gerrit J. Poelarends
Publié dans: Angewandte Chemie International Edition, 2023, ISSN 1521-3757
Éditeur: Wiley VCH
DOI: 10.1002/anie.202309012

Alternative coenzymes for biocatalysis

Auteurs: Alice Guarneri, Willem JH van Berkel, Caroline E Paul
Publié dans: Current Opinion in Biotechnology, Numéro 60, 2019, Page(s) 63-71, ISSN 0958-1669
Éditeur: Elsevier BV
DOI: 10.1016/j.copbio.2019.01.001

Enzymatic Ring‐Opening Polymerization of Lactones: Traditional Approaches and Alternative Strategies

Auteurs: Jennifer Engel, Alex Cordellier, Lei Huang, Selin Kara
Publié dans: ChemCatChem, 2019, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201900976

Photo-Biocatalysis: Biotransformations in the Presence of Light

Auteurs: Luca Schmermund, Valentina Jurkaš, F. Feyza Özgen, Giovanni D. Barone, Hanna C. Büchsenschütz, Christoph K. Winkler, Sandy Schmidt, Robert Kourist, Wolfgang Kroutil
Publié dans: ACS Catalysis, Numéro 9/5, 2019, Page(s) 4115-4144, ISSN 2155-5435
Éditeur: American Chemical Society
DOI: 10.1021/acscatal.9b00656

Photobiocatalytic Oxyfunctionalization with High Reaction Rate using a Baeyer–Villiger Monooxygenase from Burkholderia xenovorans in Metabolically Engineered Cyanobacteria

Auteurs: Elif Erdem, Lenny Malihan-Yap, Leen Assil-Companioni, Hanna Grimm, Giovanni Davide Barone, Carole Serveau-Avesque, Agnes Amouric, Katia Duquesne, Véronique de Berardinis, Yagut Allahverdiyeva, Véronique Alphand and Robert Kourist
Publié dans: ACS Catalysis, Numéro 12, 2022, Page(s) 66–72, ISSN 2155-5435
Éditeur: American Chemical Society
DOI: 10.1021/acscatal.1c04555

Artifizielle Lichtsammelkomplexe ermöglichen Rieske‐Oxygenase‐ katalysierte Hydroxylierungen in nicht‐photosynthetischen Zellen

Auteurs: Feyza Özgen, F.; Runda, Michael E.; Burek, Bastien O.; Wied, Peter; Bloh, Jonathan Z.; Kourist, Robert; Schmidt, Sandy
Publié dans: Angewandte Chemie, Numéro 3, 2020, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/ange.201914519

An Optimized System for the Study of Rieske Oxygenase-catalyzed Hydroxylation Reactions In vitro

Auteurs: Michael Ernst Runda, Bastian Kremser, Fatma Feyza Özgen, Sandy Schmidt
Publié dans: ChemCatChem, 2023, ISSN 1867-3899
Éditeur: Wiley-VCH
DOI: 10.1002/cctc.202300371

Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor

Auteurs: C. K. Winkler, S. Simić, V. Jurkaš, S. Bierbaumer, L. Schmermund, S. Poschenrieder, S. A. Berger, E. Kulterer, R. Kourist, W. Kroutil
Publié dans: ChemPhotoChem, 2021, ISSN 2367-0932
Éditeur: Wiely-VCH
DOI: 10.1002/cptc.202100109

Expression and activity of heterologous hydroxyisocaproate dehydrogenases in Synechocystis sp. PCC 6803 ΔhoxYH

Auteurs: V. Jurkaš, C. K. Winkler, S. Poschenrieder, P. Oliveira, C. C. Pacheco, E. A. Ferreira, F. Weissensteiner, P. De Santis, S. Kara, R. Kourist, P Tamagnini*, W. Kroutil
Publié dans: Eng. Microbiol., Numéro 1, 2022, Page(s) 100008, ISSN 2667-3703
Éditeur: Elsevier B.V.
DOI: 10.1016/j.engmic.2021.100008

Extending the Library of Light‐Dependent Protochlorophyllide Oxidoreductases and their Solvent Tolerance, Stability in Light and Cofactor Flexibility

Auteurs: L. Schmermund, S. Bierbaumer, V. K. Schein, C. K. Winkler, S. Kara, W. Kroutil
Publié dans: ChemCatchem, Numéro 12, 2020, Page(s) 4044-4051, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202000561

Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways

Auteurs: Luca Schmermund; Susanne Reischauer; Sarah Bierbaumer; Christoph K. Winkler; Alba Diaz-Rodriguez; Lee Edwards; Selin Kara; Tamara Mielke; Jared Cartwright; Gideon Grogan; Bartholomäus Pieber; Wolfgang Kroutil
Publié dans: Angweandte Chemie, International Edition, Numéro 133, 2021, Page(s) 7041-7045, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202100164

Divorce in the two-component BVMO family: the single oxygenase for enantioselective chemo-enzymatic Baeyer–Villiger oxidations

Auteurs: R. Röllig, C. E. Paul, M. Claeys-Bruno, K Duquesne, S. Kara, V. Alphand
Publié dans: Organic and Biomolecular Chemistry, 2021, Page(s) 3441-3450, ISSN 1477-0520
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d1ob00015b