New nanomaterials for neural stem cells drug delivery

Deliverables

Agenda list of participants and synopsis of content of the NanoStem international conference

Outreach activities and public engagement

Overview of implemented outreach and public engagement activities Promotional materials and advertising photographs and links to web pages

Presentation of results at international conferences

Details of postersoral presentations by ESRs at international conferences At least one per ESR is required

Project Website

Project Website URL.

Publications of results in peer-reviewed journals

At least one publication in peerreviewed journal document uploaded per ESR

Publications

Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

Author(s): Monica L. Fernández-Quintero, Clarissa A. Seidler, Patrick K. Quoika, and Klaus R. Liedl
Published in: Frontiers of Molecular Biosciences, 2021, ISSN 2296-889X
Publisher: Frontiers Media S.A
DOI: 10.3389/fmolb.2021.639166

Reliable release testing for nanoparticles with the NanoDis System, an innovative sample and separate technique

Author(s): Sonia M.Lombardo, Nazende Günday Türeli, Marcus Koch, Marc Schneider, Akif E.Türeli
Published in: International Journal of Pharmaceutics, 2021, ISSN 0020-0255
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2021.121215

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke.

Author(s): Sara Bernardo-Castro; Inês Albino; Ángela María Barrera-Sandoval; Francesca Tomatis; João André Sousa; Emanuel Martins; Susana Simões; Miguel M. Lino; Lino Ferreira; João Sargento-Freitas
Published in: Life, Issue 20751729, 2021, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life11060482

Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review

Author(s): Sara Bernardo-Castro, Helena Donato, Lino Ferreira, João Sargento-Freitas
Published in: BMJ Open, 2020, ISSN 0959-8138
Publisher: BMJ
DOI: 10.1136/bmjopen-2020-039280

Effect of heterogeneous and homogeneous polymerisation on the structure of pNIPAm nanogels

Author(s): Alena Vdovchenko; Amanda K. Pearce; Mark Freeley; Rachel K. O'Reilly; Marina Resmini
Published in: polymer chemistry, Issue 20440804, 2021, ISSN 2044-0804
Publisher: RSC Polymer Chemistry Series
DOI: 10.1039/d1py01333e

Miniaturization and Automation of a Human In Vitro Blood-Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery.

Author(s): Moya, E., Vandenhaute, E., Rizzi, E., Boucau, M. C., Hachani, J., Maubon, N., Gosselet, F., & Dehouck, M. P.
Published in: Pharmaceutics, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13060892

Thermosensitive hydration of four acrylamide-based polymers in coil and globule conformations

Author(s): Patrick K. Quoika, Maren Podewitz, Yin Wang, Anna S. Kamenik, Johannes R. Loeffler, and Klaus R. Liedl
Published in: The Journal of Physical Chemistry B, Issue 2, 2020, Page(s) 9745 - 9756, ISSN 1520-5207
Publisher: American Chemistry Society
DOI: 10.1021/acs.jpcb.0c07232

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Author(s): Eleonora Rizzi, Clémence Deligne, Lucie Dehouck, Roberta Bilardo, Yasutero Sano, Fumitaka Shimizu, Takashi Kanda, Marina Resmini, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Published in: Jove, 2021, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/63134

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

Author(s): Roberta Bilardo,Federico Traldi,Alena Vdovchenko,Marina Resmini
Published in: Wires Nanomedicine and Nanobiotechnology, 2022, ISSN 1939-0041
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/wnan.1788

Key for crossing the BBB with nanoparticles: the rational design

Author(s): Sonia M Lombardo, Marc Schneider, Akif E Türeli, Nazende Günday Türeli
Published in: Beilstein Journal of Nanotechnology, Issue 11, 2020, Page(s) 866-883, ISSN 2190-4286
Publisher: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/bjnano.11.72

Macrocycle Cell Permeability Measured by Solvation Free Energies in Polar and Apolar Environments

Author(s): Anna S. Kamenik, Johannes Kraml, Florian Hofer, Franz Waibl, Patrick K. Quoika, Ursula Kahler, Michael Schauperl, Klaus R. Liedl
Published in: Journal of Chemical Information and Modeling, Issue 60/7, 2020, Page(s) 3508-3517, ISSN 1549-9596
Publisher: American Chemical Society
DOI: 10.1021/acs.jcim.0c00280

Implementation of the Freely Jointed Chain Model to Assess Kinetics and Thermodynamics of Thermosensitive Coil–Globule Transition by Markov States

Author(s): Patrick K. Quoika, Monica L. Fernández-Quintero, Maren Podewitz, Florian Hofer, and Klaus R. Liedl
Published in: The Journal of Physical Chemistry B, 2021, ISSN 1520-5207
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.1c01946

X-Entropy: A Parallelized Kernel Density Estimator with Automated Bandwidth Selection to Calculate Entropy

Author(s): Johannes Kraml, Florian Hofer, Patrick K. Quoika, Anna S. Kamenik, and Klaus R. Liedl
Published in: Journal of Chemical Information and Modeling, 2021, ISSN 1520-5142
Publisher: American Chemical Society
DOI: 10.1021/acs.jcim.0c01375

Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells

Author(s): Elisa Moya, Sonia Lombardo, Elodie Vandenhaute, Marc Schneider, Caroline Mysiorek, Akif Türeli, Takeshi Kanda, Fumitaka Shimizu, Yasuteru Sano, Nathalie Maubon, Fabien Gosselet, Nazende Günday-Türeli, Marie-Pierre Dehouck
Published in: International Journal of Pharmaceutics, 2022, ISSN 0020-0255
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2022.121780

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Author(s): Sara Bernardo-Castro, João André Sousa, Ana Brás, Carla Cecília, Bruno Rodrigues, Luciano Almendra, Cristina Machado, Gustavo Santo, Fernando Silva, Lino Ferreira, Isabel Santana, João Sargento-Freitas
Published in: Frontiers in Neurology, 2020, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2020.594672

Deliverables

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