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New nanomaterials for neural stem cells drug delivery


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Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

Author(s): Monica L. Fernández-Quintero, Clarissa A. Seidler, Patrick K. Quoika, and Klaus R. Liedl
Published in: Frontiers of Molecular Biosciences, 2021, ISSN 2296-889X
Publisher: Frontiers Media S.A
DOI: 10.3389/fmolb.2021.639166

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke.

Author(s): Sara Bernardo-Castro; Inês Albino; Ángela María Barrera-Sandoval; Francesca Tomatis; João André Sousa; Emanuel Martins; Susana Simões; Miguel M. Lino; Lino Ferreira; João Sargento-Freitas
Published in: Life, 5, 2021, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life11060482

Coil-Globule Transition Thermodynamics of Poly(N-isopropylacrylamide).

Author(s): Podewitz, Maren; Wang, Yin; Quoika, Patrick K.; Loeffler, Johannes R.; Schauperl, Michael; Liedl, Klaus R.
Published in: J. Phys. Chem. B, 4, 2019, ISSN 1520-5207
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.9b06125

Reliable release testing for nanoparticles with the NanoDis System, an innovative sample and separate technique

Author(s): Sonia M.Lombardo, Nazende Günday Türeli, Marcus Koch, Marc Schneider, Akif E.Türeli
Published in: International Journal of Pharmaceutics, 2021, ISSN 0020-0255
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2021.121215

Thermosensitive Hydration of Four Acrylamide-Based Polymers in Coil and Globule Conformations.

Author(s): Patrick K. Quoika; Maren Podewitz; Yin Wang; Anna S. Kamenik; Johannes R. Loeffler; Klaus R. Liedl
Published in: The Journal of Physical Chemistry. B, 2, 2020, ISSN 1520-5207
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.0c07232

Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review

Author(s): Sara Bernardo-Castro, Helena Donato, Lino Ferreira, João Sargento-Freitas
Published in: BMJ Open, 2020, ISSN 0959-8138
Publisher: BMJ
DOI: 10.1136/bmjopen-2020-039280

Secretome of endothelial progenitorcells from stroke patients promotesendothelial barrier tightness and protectsagainst hypoxia-induced vascular leakage

Author(s): Loiola, R. A., García-Gabilondo, M., Grayston, A., Bugno, P., Kowalska, A., Duban-Deweer, S., Rizzi, E., Hachani, J., Sano, Y., Shimizu, F., Kanda, T., Mysiorek, C., Mazurek, M. P., Rosell, A., & Gosselet, F.
Published in: Stem cell research & therapy, 2021, ISSN 0967-0912
Publisher: Institute of Materials
DOI: 10.1186/s13287-021-02608-y

Miniaturization and Automation of a Human In Vitro Blood-Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery.

Author(s): Moya, E., Vandenhaute, E., Rizzi, E., Boucau, M. C., Hachani, J., Maubon, N., Gosselet, F., & Dehouck, M. P.
Published in: Pharmaceutics, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13060892

Effect of heterogeneous and homogeneous polymerisation on the structure of pNIPAm nanogels

Author(s): Alena Vdovchenko; Amanda K. Pearce; Mark Freeley; Rachel K. O'Reilly; Marina Resmini
Published in: polymer chemistry, 2021, ISSN 2044-0804
Publisher: RSC Polymer Chemistry Series
DOI: 10.1039/d1py01333e

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Author(s): Eleonora Rizzi, Clémence Deligne, Lucie Dehouck, Roberta Bilardo, Yasutero Sano, Fumitaka Shimizu, Takashi Kanda, Marina Resmini, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Published in: Jove, 2021, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/63134

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

Author(s): Roberta Bilardo,Federico Traldi,Alena Vdovchenko,Marina Resmini
Published in: Wires Nanomedicine and Nanobiotechnology, 2022, ISSN 1939-0041
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/wnan.1788

Key for crossing the BBB with nanoparticles: the rational design

Author(s): Sonia M Lombardo, Marc Schneider, Akif E Türeli, Nazende Günday Türeli
Published in: Beilstein Journal of Nanotechnology, 11, 2020, Page(s) 866-883, ISSN 2190-4286
Publisher: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/bjnano.11.72

Macrocycle Cell Permeability Measured by Solvation Free Energies in Polar and Apolar Environments

Author(s): Anna S. Kamenik, Johannes Kraml, Florian Hofer, Franz Waibl, Patrick K. Quoika, Ursula Kahler, Michael Schauperl, Klaus R. Liedl
Published in: Journal of Chemical Information and Modeling, 60/7, 2020, Page(s) 3508-3517, ISSN 1549-9596
Publisher: American Chemical Society
DOI: 10.1021/acs.jcim.0c00280

Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration

Author(s): HugoFernandes, AlessandraZonnari, RicardoAbreu, SezinAday, MartaBarão, InêsAlbino, MiguelLino, AnaBranco, CátiaSeabra, TâniaBarata, Ermelindo C.Leal, José GuilhermeTralhão, LinoGonçalves, Alwinde Jong, Hendrika A.B.Peters, Margreet Vries, Paulada Costa Martins, Paul H.A.Quax, LinoFerreira
Published in: Molecular Therapy - Nucleic Acids, 2022, ISSN 0020-0255
Publisher: Elsevier BV
DOI: 10.1016/j.omtn.2022.03.018

Implementation of the Freely Jointed Chain Model to Assess Kinetics and Thermodynamics of Thermosensitive Coil–Globule Transition by Markov States

Author(s): Patrick K. Quoika, Monica L. Fernández-Quintero, Maren Podewitz, Florian Hofer, and Klaus R. Liedl
Published in: The Journal of Physical Chemistry B, 2021, ISSN 1520-5207
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.1c01946

X-Entropy: A Parallelized Kernel Density Estimator with Automated Bandwidth Selection to Calculate Entropy

Author(s): Johannes Kraml, Florian Hofer, Patrick K. Quoika, Anna S. Kamenik, and Klaus R. Liedl
Published in: Journal of Chemical Information and Modeling, 2021, ISSN 1520-5142
Publisher: American Chemical Society
DOI: 10.1021/acs.jcim.0c01375

Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells

Author(s): Elisa Moya, Sonia Lombardo, Elodie Vandenhaute, Marc Schneider, Caroline Mysiorek, Akif Türeli, Takeshi Kanda, Fumitaka Shimizu, Yasuteru Sano, Nathalie Maubon, Fabien Gosselet, Nazende Günday-Türeli, Marie-Pierre Dehouck
Published in: International Journal of Pharmaceutics, 2022, ISSN 0020-0255
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2022.121780

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Author(s): Sara Bernardo-Castro, João André Sousa, Ana Brás, Carla Cecília, Bruno Rodrigues, Luciano Almendra, Cristina Machado, Gustavo Santo, Fernando Silva, Lino Ferreira, Isabel Santana, João Sargento-Freitas
Published in: Frontiers in Neurology, 2020, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2020.594672