New nanomaterials for neural stem cells drug delivery

Leistungen

Agenda list of participants and synopsis of content of the NanoStem international conference

Outreach activities and public engagement

Overview of implemented outreach and public engagement activities Promotional materials and advertising photographs and links to web pages

Presentation of results at international conferences

Details of postersoral presentations by ESRs at international conferences At least one per ESR is required

Project Website

Project Website URL.

Publications of results in peer-reviewed journals

At least one publication in peerreviewed journal document uploaded per ESR

Veröffentlichungen

Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics

Autoren: Monica L. Fernández-Quintero, Clarissa A. Seidler, Patrick K. Quoika, and Klaus R. Liedl
Veröffentlicht in: Frontiers of Molecular Biosciences, 2021, ISSN 2296-889X
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fmolb.2021.639166

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke.

Autoren: Sara Bernardo-Castro; Inês Albino; Ángela María Barrera-Sandoval; Francesca Tomatis; João André Sousa; Emanuel Martins; Susana Simões; Miguel M. Lino; Lino Ferreira; João Sargento-Freitas
Veröffentlicht in: Life, Issue 5, 2021, ISSN 2075-1729
Herausgeber: MDPI
DOI: 10.3390/life11060482

Coil-Globule Transition Thermodynamics of Poly(N-isopropylacrylamide).

Autoren: Podewitz, Maren; Wang, Yin; Quoika, Patrick K.; Loeffler, Johannes R.; Schauperl, Michael; Liedl, Klaus R.
Veröffentlicht in: J. Phys. Chem. B, Issue 4, 2019, ISSN 1520-5207
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jpcb.9b06125

Reliable release testing for nanoparticles with the NanoDis System, an innovative sample and separate technique

Autoren: Sonia M.Lombardo, Nazende Günday Türeli, Marcus Koch, Marc Schneider, Akif E.Türeli
Veröffentlicht in: International Journal of Pharmaceutics, 2021, ISSN 0020-0255
Herausgeber: Elsevier BV
DOI: 10.1016/j.ijpharm.2021.121215

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke.

Autoren: Sara Bernardo-Castro; Inês Albino; Ángela María Barrera-Sandoval; Francesca Tomatis; João André Sousa; Emanuel Martins; Susana Simões; Miguel M. Lino; Lino Ferreira; João Sargento-Freitas
Veröffentlicht in: Life, Issue 20751729, 2021, ISSN 2075-1729
Herausgeber: MDPI
DOI: 10.3390/life11060482

Thermosensitive Hydration of Four Acrylamide-Based Polymers in Coil and Globule Conformations.

Autoren: Patrick K. Quoika; Maren Podewitz; Yin Wang; Anna S. Kamenik; Johannes R. Loeffler; Klaus R. Liedl
Veröffentlicht in: The Journal of Physical Chemistry. B, Issue 2, 2020, ISSN 1520-5207
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jpcb.0c07232

Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review

Autoren: Sara Bernardo-Castro, Helena Donato, Lino Ferreira, João Sargento-Freitas
Veröffentlicht in: BMJ Open, 2020, ISSN 0959-8138
Herausgeber: BMJ
DOI: 10.1136/bmjopen-2020-039280

Effect of heterogeneous and homogeneous polymerisation on the structure of pNIPAm nanogels

Autoren: Alena Vdovchenko; Amanda K. Pearce; Mark Freeley; Rachel K. O'Reilly; Marina Resmini
Veröffentlicht in: polymer chemistry, Issue 20440804, 2021, ISSN 2044-0804
Herausgeber: RSC Polymer Chemistry Series
DOI: 10.1039/d1py01333e

Secretome of endothelial progenitorcells from stroke patients promotesendothelial barrier tightness and protectsagainst hypoxia-induced vascular leakage

Autoren: Loiola, R. A., García-Gabilondo, M., Grayston, A., Bugno, P., Kowalska, A., Duban-Deweer, S., Rizzi, E., Hachani, J., Sano, Y., Shimizu, F., Kanda, T., Mysiorek, C., Mazurek, M. P., Rosell, A., & Gosselet, F.
Veröffentlicht in: Stem cell research & therapy, 2021, ISSN 0967-0912
Herausgeber: Institute of Materials
DOI: 10.1186/s13287-021-02608-y

Miniaturization and Automation of a Human In Vitro Blood-Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery.

Autoren: Moya, E., Vandenhaute, E., Rizzi, E., Boucau, M. C., Hachani, J., Maubon, N., Gosselet, F., & Dehouck, M. P.
Veröffentlicht in: Pharmaceutics, 2021, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13060892

Thermosensitive hydration of four acrylamide-based polymers in coil and globule conformations

Autoren: Patrick K. Quoika, Maren Podewitz, Yin Wang, Anna S. Kamenik, Johannes R. Loeffler, and Klaus R. Liedl
Veröffentlicht in: The Journal of Physical Chemistry B, Issue 2, 2020, Page(s) 9745 - 9756, ISSN 1520-5207
Herausgeber: American Chemistry Society
DOI: 10.1021/acs.jpcb.0c07232

Effect of heterogeneous and homogeneous polymerisation on the structure of pNIPAm nanogels

Autoren: Alena Vdovchenko; Amanda K. Pearce; Mark Freeley; Rachel K. O'Reilly; Marina Resmini
Veröffentlicht in: polymer chemistry, 2021, ISSN 2044-0804
Herausgeber: RSC Polymer Chemistry Series
DOI: 10.1039/d1py01333e

A Triple Culture Cell System Modeling the Human Blood-Brain Barrier

Autoren: Eleonora Rizzi, Clémence Deligne, Lucie Dehouck, Roberta Bilardo, Yasutero Sano, Fumitaka Shimizu, Takashi Kanda, Marina Resmini, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek
Veröffentlicht in: Jove, 2021, ISSN 1940-087X
Herausgeber: MYJoVE Corporation
DOI: 10.3791/63134

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

Autoren: Roberta Bilardo,Federico Traldi,Alena Vdovchenko,Marina Resmini
Veröffentlicht in: Wires Nanomedicine and Nanobiotechnology, 2022, ISSN 1939-0041
Herausgeber: John Wiley & Sons Inc.
DOI: 10.1002/wnan.1788

Key for crossing the BBB with nanoparticles: the rational design

Autoren: Sonia M Lombardo, Marc Schneider, Akif E Türeli, Nazende Günday Türeli
Veröffentlicht in: Beilstein Journal of Nanotechnology, Issue 11, 2020, Page(s) 866-883, ISSN 2190-4286
Herausgeber: Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI: 10.3762/bjnano.11.72

Macrocycle Cell Permeability Measured by Solvation Free Energies in Polar and Apolar Environments

Autoren: Anna S. Kamenik, Johannes Kraml, Florian Hofer, Franz Waibl, Patrick K. Quoika, Ursula Kahler, Michael Schauperl, Klaus R. Liedl
Veröffentlicht in: Journal of Chemical Information and Modeling, Issue 60/7, 2020, Page(s) 3508-3517, ISSN 1549-9596
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jcim.0c00280

Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration

Autoren: HugoFernandes, AlessandraZonnari, RicardoAbreu, SezinAday, MartaBarão, InêsAlbino, MiguelLino, AnaBranco, CátiaSeabra, TâniaBarata, Ermelindo C.Leal, José GuilhermeTralhão, LinoGonçalves, Alwinde Jong, Hendrika A.B.Peters, Margreet R.de Vries, Paulada Costa Martins, Paul H.A.Quax, LinoFerreira
Veröffentlicht in: Molecular Therapy - Nucleic Acids, 2022, ISSN 0020-0255
Herausgeber: Elsevier BV
DOI: 10.1016/j.omtn.2022.03.018

Implementation of the Freely Jointed Chain Model to Assess Kinetics and Thermodynamics of Thermosensitive Coil–Globule Transition by Markov States

Autoren: Patrick K. Quoika, Monica L. Fernández-Quintero, Maren Podewitz, Florian Hofer, and Klaus R. Liedl
Veröffentlicht in: The Journal of Physical Chemistry B, 2021, ISSN 1520-5207
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jpcb.1c01946

X-Entropy: A Parallelized Kernel Density Estimator with Automated Bandwidth Selection to Calculate Entropy

Autoren: Johannes Kraml, Florian Hofer, Patrick K. Quoika, Anna S. Kamenik, and Klaus R. Liedl
Veröffentlicht in: Journal of Chemical Information and Modeling, 2021, ISSN 1520-5142
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jcim.0c01375

Interaction of surfactant coated PLGA nanoparticles with in vitro human brain-like endothelial cells

Autoren: Elisa Moya, Sonia Lombardo, Elodie Vandenhaute, Marc Schneider, Caroline Mysiorek, Akif Türeli, Takeshi Kanda, Fumitaka Shimizu, Yasuteru Sano, Nathalie Maubon, Fabien Gosselet, Nazende Günday-Türeli, Marie-Pierre Dehouck
Veröffentlicht in: International Journal of Pharmaceutics, 2022, ISSN 0020-0255
Herausgeber: Elsevier BV
DOI: 10.1016/j.ijpharm.2022.121780

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Autoren: Sara Bernardo-Castro, João André Sousa, Ana Brás, Carla Cecília, Bruno Rodrigues, Luciano Almendra, Cristina Machado, Gustavo Santo, Fernando Silva, Lino Ferreira, Isabel Santana, João Sargento-Freitas
Veröffentlicht in: Frontiers in Neurology, 2020, ISSN 1664-2295
Herausgeber: Frontiers Research Foundation
DOI: 10.3389/fneur.2020.594672

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