Improving Genome Editing Efficiency (IMGENE)

Informations projet

IMGENE

N° de convention de subvention: 765269

DOI

10.3030/765269

Projet clôturé

Date de signature de la CE 18 Juillet 2017

Date de début 1 Septembre 2017

Date de fin 31 Août 2021

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 2 068 409,16

Contribution de l’UE

€ 2 068 409,16

Coordonné par

KOBENHAVNS UNIVERSITET
Denmark

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (9)

Final report on 5 ECTS in transferable skill training per ESR

Final report on 5 ECTS in transferable skill training per ESR will be written

Establishment of Supervisory Board

A Supervisory Board will be established

Common ESR outreach activity (1st Summer School)

Common ESR outreach activity (1st Summer School) will be undertaken

Common ESR outreach activity (2nd Summer School)

Common ESR outreach activity (2nd Summer School) will be undertaken

Report on recruitment

A report on recruitment will be written

Final report on 5 ECTS in ethics training per ESR

Final report on 5 ECTS in ethics training per ESR will be written

IMGENE twitter, facebook, and 3-min movies (genome editing, ethics)

IMGENE twitteraccount, facebook page, and 3-min movies (on e.g. genome editing, ethics) will be created

Common ESR outreach activity (3rd Summer School)

Common ESR outreach activity 3rd Summer School will be undertaken

Final report on 5 ECTS in outreach and dissemination training per ESR

Final report on 5 ECTS in outreach and dissemination training per ESR will be written

Open Research Data Pilot (1)

Data Management Plan

A Data Management Plan will be written

Websites, patent fillings, videos etc. (1)

IMGENE homepage

A project homepage will be established

Publications

Peer reviewed articles (7)

CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review

Auteurs: Syding, Linn Amanda; Nickl, Petr; Kasparek, Petr; Sedlacek, Radislav
Publié dans: CELLS, Numéro Volume: 9 Numéro: 4 Article Number: 993, 2020, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9040993

Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny

Auteurs: Francesca Tasca, Qian Wang, Manuel A.F.V. Gonçalves
Publié dans: Cells, Numéro 9/4, 2020, Page(s) 953, ISSN 2073-4409
Éditeur: cells
DOI: 10.3390/cells9040953

DNA Damage: From Threat to Treatment

Auteurs: Antonio Carusillo, Claudio Mussolino
Publié dans: Cells, Numéro 9/7, 2020, Page(s) 1665, ISSN 2073-4409
Éditeur: PMC
DOI: 10.3390/cells9071665

A versatile reporter system for multiplexed screening of effective epigenome editors

Auteurs: Maria Silvia Roman Azcona, Yongxing Fang, Antonio Carusillo, Toni Cathomen, Claudio Mussolino
Publié dans: Nature Protocols, Numéro 15/10, 2020, Page(s) 3410-3440, ISSN 1754-2189
Éditeur: Nature Publishing Group
DOI: 10.1038/s41596-020-0380-y

Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery

Auteurs: Anders Lundin, Michelle J. Porritt, Himjyot Jaiswal, Frank Seeliger, Camilla Johansson, Abdel Wahad Bidar, Lukas Badertscher, Sandra Wimberger, Emma J. Davies, Elizabeth Hardaker, Carla P. Martins, Emily James, Therese Admyre, Amir Taheri-Ghahfarokhi, Jenna Bradley, Anna Schantz, Babak Alaeimahabadi, Maryam Clausen, Xiufeng Xu, Lorenz M. Mayr, Roberto Nitsch, Mohammad Bohlooly-Y, Simon T. Barry, M
Publié dans: Nature Communications, Numéro 11/1, 2020, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-020-18548-9

Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

Auteurs: Nadja Bischoff, Sandra Wimberger, Marcello Maresca, Cord Brakebusch
Publié dans: Cells, Numéro 9/5, 2020, Page(s) 1318, ISSN 2073-4409
Éditeur: cells
DOI: 10.3390/cells9051318

Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Auteurs: Xiaoyu Chen, Francesca Tasca, Qian Wang, Jin Liu, Josephine M Janssen, Marcella D Brescia, Milena Bellin, Karoly Szuhai, Josefin Kenrick, Richard L Frock, Manuel A F V Gonçalves
Publié dans: Nucleic Acids Research, 2019, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkz1121